A fully-virulent retargeted oncolytic HSV armed with IL-12 elicits local immunity and vaccine therapy towards distant tumors von Leoni, Valerio, Vannini, Andrea, Gatta, Valentina, Rambaldi, Julie, Sanapo, Mara, Barboni, Catia, Zaghini, Anna, Nanni, Patrizia, Lollini, Pier-Luigi, Casiraghi, Costanza, Campadelli-Fiume, Gabriella

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Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations von Nanni, Patrizia, Landuzzi, Lorena, Manara, Maria Cristina, Righi, Alberto, Nicoletti, Giordano, Cristalli, Camilla, Pasello, Michela, Parra, Alessandro, Carrabotta, Marianna, Ferracin, Manuela, Palladini, Arianna, Ianzano, Marianna L., Giusti, Veronica, Ruzzi, Francesca, Magnani, Mauro, Donati, Davide Maria, Picci, Piero, Lollini, Pier-Luigi, Scotlandi, Katia

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Targeting PCSK9, through an innovative cVLP-based vaccine, enhanced the therapeutic activity of a cVLP-HER2 vaccine in a preclinical model of HER2-positive mammary carcinoma von Scalambra, Laura, Ruzzi, Francesca, Pittino, Olga Maria, Semprini, Maria Sofia, Cappello, Chiara, Angelicola, Stefania, Palladini, Arianna, Nanni, Patrizia, Goksøyr, Louise, Fougeroux, Cyrielle, Penichet, Manuel L, Sander, Adam Frederik, Lollini, Pier-Luigi

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Early stability and late random tumor progression of a HER2-positive primary breast cancer patient-derived xenograft von Landuzzi, Lorena, Palladini, Arianna, Ceccarelli, Claudio, Asioli, Sofia, Nicoletti, Giordano, Giusti, Veronica, Ruzzi, Francesca, Ianzano, Marianna L., Scalambra, Laura, Laranga, Roberta, Balboni, Tania, Arigoni, Maddalena, Olivero, Martina, Calogero, Raffaele A., De Giovanni, Carla, Dall’Ora, Massimiliano, Di Oto, Enrico, Santini, Donatella, Foschini, Maria Pia, Cucchi, Maria Cristina, Zanotti, Simone, Taffurelli, Mario, Nanni, Patrizia, Lollini, Pier-Luigi

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Evolution of HER2-positive mammary carcinoma: HER2 loss reveals claudin-low traits in cancer progression von Giusti, Veronica, Ruzzi, Francesca, Landuzzi, Lorena, Ianzano, Marianna L., Laranga, Roberta, Nironi, Elena, Scalambra, Laura, Nicoletti, Giordano, De Giovanni, Carla, Olivero, Martina, Arigoni, Maddalena, Calogero, Raffaele, Nanni, Patrizia, Palladini, Arianna, Lollini, Pier-Luigi

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Activated d16HER2 homodimers and SRC kinase mediate optimal efficacy for trastuzumab von Castagnoli, Lorenzo, Iezzi, Manuela, Ghedini, Gaia C, Ciravolo, Valentina, Marzano, Giulia, Lamolinara, Alessia, Zappasodi, Roberta, Gasparini, Patrizia, Campiglio, Manuela, Amici, Augusto, Chiodoni, Claudia, Palladini, Arianna, Lollini, Pier Luigi, Triulzi, Tiziana, Menard, Sylvie, Nanni, Patrizia, Tagliabue, Elda, Pupa, Serenella M

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Systemic delivery of HER2-retargeted oncolytic-HSV by mesenchymal stromal cells protects from lung and brain metastases von Leoni, Valerio, Gatta, Valentina, Palladini, Arianna, Nicoletti, Giordano, Ranieri, Dario, Dall'Ora, Massimiliano, Grosso, Valentina, Rossi, Martina, Alviano, Francesco, Bonsi, Laura, Nanni, Patrizia, Lollini, Pier-Luigi, Campadelli-Fiume, Gabriella

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Virus-like particle display of HER2 induces potent anti-cancer responses von Palladini, Arianna, Thrane, Susan, Janitzek, Christoph M., Pihl, Jessica, Clemmensen, Stine B., de Jongh, Willem Adriaan, Clausen, Thomas M., Nicoletti, Giordano, Landuzzi, Lorena, Penichet, Manuel L., Balboni, Tania, Ianzano, Marianna L., Giusti, Veronica, Theander, Thor G., Nielsen, Morten A., Salanti, Ali, Lollini, Pier-Luigi, Nanni, Patrizia, Sander, Adam F.

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Lipid rafts, caveolae, and epidermal growth factor receptor family: friends or foes? von Ruzzi, Francesca, Cappello, Chiara, Semprini, Maria Sofia, Scalambra, Laura, Angelicola, Stefania, Pittino, Olga Maria, Landuzzi, Lorena, Palladini, Arianna, Nanni, Patrizia, Lollini, Pier-Luigi

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Multiorgan metastasis of human HER-2+ breast cancer in Rag2-/-;Il2rg-/- mice and treatment with PI3K inhibitor von Nanni, Patrizia, Nicoletti, Giordano, Palladini, Arianna, Croci, Stefania, Murgo, Annalisa, Ianzano, Marianna L, Grosso, Valentina, Stivani, Valeria, Antognoli, Agnese, Lamolinara, Alessia, Landuzzi, Lorena, di Tomaso, Emmanuelle, Iezzi, Manuela, De Giovanni, Carla, Lollini, Pier-Luigi

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Immune targeting of autocrine IGF2 hampers rhabdomyosarcoma growth and metastasis von De Giovanni, Carla, Nanni, Patrizia, Landuzzi, Lorena, Ianzano, Marianna L, Nicoletti, Giordano, Croci, Stefania, Palladini, Arianna, Lollini, Pier-Luigi

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Preclinical In vivo Study of New Insulin-Like Growth Factor-I Receptor–Specific Inhibitor in Ewing's Sarcoma von MANARA, Maria C, LANDUZZI, Lorena, SCOTLANDI, Katia, NANNI, Patrizia, NICOLETTI, Giordano, ZAMBELLI, Diana, LOLLINI, Pier Luigi, NANNI, Cristina, HOFMANN, Francesco, GARCIA-ECHEVERRIA, Carlos, PICCI, Piero

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Cancer immunoprevention: from mice to early clinical trials von Palladini, Arianna, Landuzzi, Lorena, Lollini, Pier-Luigi, Nanni, Patrizia

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Inhibition of human tumor growth in mice by an oncolytic herpes simplex virus designed to target solely HER-2-positive cells von Menotti, Laura, Nicoletti, Giordano, Gatta, Valentina, Croci, Stefania, Landuzzi, Lorena, De Giovanni, Carla, Nanni, Patrizia, Lollini, Pier-Luigi, Campadelli-Fiume, Gabriella

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Rethinking herpes simplex virus: the way to oncolytic agents von Campadelli-Fiume, Gabriella, De Giovanni, Carla, Gatta, Valentina, Nanni, Patrizia, Lollini, Pier-Luigi, Menotti, Laura

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HER Tyrosine Kinase Family and Rhabdomyosarcoma: Role in Onset and Targeted Therapy von De Giovanni, Carla, Landuzzi, Lorena, Palladini, Arianna, Nicoletti, Giordano, Nanni, Patrizia, Lollini, Pier-Luigi

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Modeling the competition between lung metastases and the immune system using agents von Pennisi, Marzio, Pappalardo, Francesco, Palladini, Ariannna, Nicoletti, Giordano, Nanni, Patrizia, Lollini, Pier-Luigi, Motta, Santo

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The Promise of Preventive Cancer Vaccines von Lollini, Pier-Luigi, Cavallo, Federica, Nanni, Patrizia, Quaglino, Elena

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Preclinical therapy of disseminated HER-2⁺ ovarian and breast carcinomas with a HER-2-retargeted oncolytic herpesvirus von Nanni, Patrizia, Gatta, Valentina, Menotti, Laura, De Giovanni, Carla, Ianzano, Marianna, Palladini, Arianna, Grosso, Valentina, Dall'ora, Massimiliano, Croci, Stefania, Nicoletti, Giordano, Landuzzi, Lorena, Iezzi, Manuela, Campadelli-Fiume, Gabriella, Lollini, Pier-Luigi

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OX40 triggering concomitant to IL12-engineered cell vaccine hampers the immunoprevention of HER2/neu-driven mammary carcinogenesis von Nanni, Patrizia, De Giovanni, Carla, Burocchi, Alessia, Nicoletti, Giordano, Landuzzi, Lorena, Palladini, Arianna, Ianzano, Marianna Lucia, Arioli, Ivano, Colombo, Mario P., Lollini, Pier-Luigi

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