The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models von Katayama, Ryohei, Gong, Bo, Togashi, Noriko, Miyamoto, Masaya, Kiga, Masaki, Iwasaki, Shiho, Kamai, Yasuki, Tominaga, Yuichi, Takeda, Yasuyuki, Kagoshima, Yoshiko, Shimizu, Yuki, Seto, Yosuke, Oh-hara, Tomoko, Koike, Sumie, Nakao, Naoki, Hanzawa, Hiroyuki, Watanabe, Kengo, Yoda, Satoshi, Yanagitani, Noriko, Hata, Aaron N., Shaw, Alice T., Nishio, Makoto, Fujita, Naoya, Isoyama, Takeshi

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Novel LCAT (Lecithin:Cholesterol Acyltransferase) Activator DS-8190a Prevents the Progression of Plaque Accumulation in Atherosclerosis Models von Sasaki, Masato, Delawary, Mina, Sakurai, Hidetaka, Kobayashi, Hideki, Nakao, Naoki, Tsuru, Hiromi, Fukushima, Yumiko, Honzumi, Shoko, Moriyama, Sachiko, Wada, Naoya, Kaneko, Toshio, Yamada, Keisuke, Terasaka, Naoki, Kubota, Kazuishi

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Four cases of cytokine storm after COVID-19 vaccination: Case report von Murata, Kazuhiro, Nakao, Naoki, Ishiuchi, Naoki, Fukui, Takafumi, Katsuya, Narutaka, Fukumoto, Wataru, Oka, Hiroko, Yoshikawa, Naotaka, Nagao, Takafumi, Namera, Akira, Kakimoto, Naoya, Oue, Naohide, Awai, Kazuo, Yoshimoto, Kanji, Nagao, Masataka

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Comparison of therapeutic effects of mesenchymal stem cells derived from superficial and deep subcutaneous adipose tissues von Ishiuchi, Naoki, Nakashima, Ayumu, Maeda, Satoshi, Miura, Yoshie, Miyasako, Kisho, Sasaki, Kensuke, Uchiki, Toshio, Sasaki, Ayano, Nagamatsu, Shogo, Nakao, Naoki, Nagao, Masataka, Masaki, Takao

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Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors von Goto, Taiji, Shiina, Akiko, Yoshino, Toshiharu, Mizukami, Kiyoshi, Hirahara, Kazuki, Suzuki, Osamu, Sogawa, Yoshitaka, Takahashi, Tomoko, Mikkaichi, Tsuyoshi, Nakao, Naoki, Takahashi, Mizuki, Hasegawa, Masashi, Sasaki, Shigeki

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Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT von Nakao, Naoki, Ueno, Masaharu, Sakai, Shota, Egawa, Daichi, Hanzawa, Hiroyuki, Kawasaki, Shohei, Kumagai, Keigo, Suzuki, Makoto, Kobayashi, Shu, Hanada, Kentaro

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Reassessment of the unique mode of binding between angiotensin II type 1 receptor and their blockers von Miura, Shin-Ichiro, Nakao, Naoki, Hanzawa, Hiroyuki, Matsuo, Yoshino, Saku, Keijiro, Karnik, Sadashiva S

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Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors von Goto, Taiji, Shiina, Akiko, Yoshino, Toshiharu, Mizukami, Kiyoshi, Hirahara, Kazuki, Suzuki, Osamu, Sogawa, Yoshitaka, Takahashi, Tomoko, Mikkaichi, Tsuyoshi, Nakao, Naoki, Takahashi, Mizuki, Hasegawa, Masashi, Sasaki, Shigeki

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Identification of the 5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives as highly selective PDE4B inhibitors von Goto, Taiji, Shiina, Akiko, Murata, Takeshi, Tomii, Masato, Yamazaki, Takanori, Yoshida, Ken-ichi, Yoshino, Toshiharu, Suzuki, Osamu, Sogawa, Yoshitaka, Mizukami, Kiyoshi, Takagi, Nana, Yoshitomi, Tomomi, Etori, Maki, Tsuchida, Hiroshi, Mikkaichi, Tsuyoshi, Nakao, Naoki, Takahashi, Mizuki, Takahashi, Hisashi, Sasaki, Shigeki

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Small molecules with similar structures exhibit agonist, neutral antagonist or inverse agonist activity toward angiotensin II type 1 receptor von Miura, Shin-ichiro, Kiya, Yoshihiro, Hanzawa, Hiroyuki, Nakao, Naoki, Fujino, Masahiro, Imaizumi, Satoshi, Matsuo, Yoshino, Yanagisawa, Hiroaki, Koike, Hiroyuki, Komuro, Issei, Karnik, Sadashiva S, Saku, Keijiro

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Path Planning and Traveling Control for Pesticide-Spraying Robot in Greenhouse von Nakao, Naoki, Suzuki, Hiroshi, Kitajima, Takahiro, Kuwahara, Akinobu, Yasuno, Takashi

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Clinical and genetic characterizations of 16q-linked autosomal dominant spinocerebellar ataxia (AD-SCA) and frequency analysis of AD-SCA in the Japanese population von Nozaki, Hiroaki, Ikeuchi, Takeshi, Kawakami, Akio, Kimura, Akio, Koide, Reiji, Tsuchiya, Miyuki, Nakmura, Yuusaku, Mutoh, Tatsuro, Yamamoto, Hiroko, Nakao, Naoki, Sahashi, Ko, Nishizawa, Masatoyo, Onodera, Osamu

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U.S. Phase I First-in-human Study of Taletrectinib (DS-6051b/AB-106), a ROS1/TRK Inhibitor, in Patients with Advanced Solid Tumors von Papadopoulos, Kyriakos P, Borazanci, Erkut, Shaw, Alice T, Katayama, Ryohei, Shimizu, Yuki, Zhu, Viola W, Sun, Thomas Yang, Wakelee, Heather A, Madison, Russell, Schrock, Alexa B, Senaldi, Giorgio, Nakao, Naoki, Hanzawa, Hiroyuki, Tachibana, Masaya, Isoyama, Takeshi, Nakamaru, Kenji, Deng, Chenhui, Li, Meijing, Fan, Frank, Zhao, Qinying, Gao, Yanfei, Seto, Takashi, Jänne, Pasi A, Ou, Sai-Hong Ignatius

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Age estimation using post-mortem computed tomography and fetal dental radiographic findings in an early to mid-pregnancy fetus: A case report von Oka, Hiroko, Asao, Yuria, Ohbayashi, Nami, Nakao, Naoki, Ishiuchi, Naoki, Fukumoto, Wataru, Matsumoto, Yoriaki, Kakimoto, Naoya, Nagao, Masataka, Kozai, Katsuyuki

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Multiple Endocrine Neoplasia Type I and Cushing's Syndrome Due to an Aggressive ACTH Producing Thymic Carcinoid von Takagi, Junko, Otake, Kazuo, Morishita, Munehiko, Kato, Harumichi, Nakao, Naoki, Yoshikawa, Kazuhiro, Ikeda, Hiroshi, Hirooka, Yoshifumi, Hattori, Yoshinobu, Larsson, Catharina, Nogimori, Tsuyoshi

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Dental radiographic information of term newborn babies within the first month: Analyzing five radiographic cases along with physical attributes in Japan von Oka, Hiroko, Asao, Yuria, Nakao, Naoki, Mitsuhata, Chieko, Matsumoto, Yoriaki, Nomura, Ryota, Kakimoto, Naoya, Nagao, Masataka, Kozai, Katsuyuki

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A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase von Kuki, Naoki, Walmsley, David L, Kanai, Kazuo, Takechi, Sho, Yoshida, Masao, Murakami, Ryo, Takano, Kohei, Tominaga, Yuichi, Takahashi, Mizuki, Ito, Shuichiro, Nakao, Naoki, Angove, Hayley, Baker, Lisa M, Carter, Edward, Dokurno, Pawel, Le Strat, Loic, Macias, Alba T, Molyneaux, Carrie-Anne, Murray, James B, Surgenor, Allan E, Hamada, Tomoaki, Hubbard, Roderick E

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(R) salsolinol N-methyltransferase activity increases in parkinsonian lymphocytes von Naoi, Makoto, Maruyama, Wakako, Nakao, Naoki, Ibi, Tohru, Sahashi, Ko, Benedetti, Margherita Strolin

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Growth Hormone Insensitivity Syndrome Associated with Syringomyelia and Type I Chiari Malformation von TAKAGI, Junko, OTAKE, Kazuo, TAKAHASHI, Masahiko, NAKAO, Naoki, HIROOKA, Yoshifumi, SAHASHI, Ko, NOGIMORI, Tsuyoshi

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A case of cerebral infarction due to invasive sino-orbital aspergillosis von Ando, Hiroaki, Niwa, Jun-ichi, Izumi, Masayuki, Nakao, Naoki, Doyu, Manabu

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