Protein Knockdown Using Methyl Bestatin−Ligand Hybrid Molecules: Design and Synthesis of Inducers of Ubiquitination-Mediated Degradation of Cellular Retinoic Acid-Binding Proteins... von Itoh, Yukihiro, Ishikawa, Minoru, Naito, Mikihiko, Hashimoto, Yuichi

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Targeted protein degradation and drug discovery von Naito, Mikihiko

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Development of protein degradation inducers of oncogenic BCR‐ABL protein by conjugation of ABL kinase inhibitors and IAP ligands von Shibata, Norihito, Miyamoto, Naoki, Nagai, Katsunori, Shimokawa, Kenichiro, Sameshima, Tomoya, Ohoka, Nobumichi, Hattori, Takayuki, Imaeda, Yasuhiro, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko

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Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy von Yamano, Koji, Kikuchi, Reika, Kojima, Waka, Hayashida, Ryota, Koyano, Fumika, Kawawaki, Junko, Shoda, Takuji, Demizu, Yosuke, Naito, Mikihiko, Tanaka, Keiji, Matsuda, Noriyuki

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Influence of EGFR-activating mutations on sensitivity to tyrosine kinase inhibitors in a KRAS mutant non-small cell lung cancer cell line von Tsukumo, Yoshinori, Naito, Mikihiko, Suzuki, Takayoshi

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Evaluation of off‐target effects of gapmer antisense oligonucleotides using human cells von Yoshida, Tokuyuki, Naito, Yuki, Yasuhara, Hidenori, Sasaki, Kiyomi, Kawaji, Hideya, Kawai, Jun, Naito, Mikihiko, Okuda, Haruhiro, Obika, Satoshi, Inoue, Takao

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Design and synthesis of peptide-based chimeric molecules to induce degradation of the estrogen and androgen receptors von Yokoo, Hidetomo, Ohoka, Nobumichi, Naito, Mikihiko, Demizu, Yosuke

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In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs) von Ohoka, Nobumichi, Okuhira, Keiichiro, Ito, Masahiro, Nagai, Katsunori, Shibata, Norihito, Hattori, Takayuki, Ujikawa, Osamu, Shimokawa, Kenichiro, Sano, Osamu, Koyama, Ryokichi, Fujita, Hisashi, Teratani, Mika, Matsumoto, Hirokazu, Imaeda, Yasuhiro, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko

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Different Degradation Mechanisms of Inhibitor of Apoptosis Proteins (IAPs) by the Specific and Nongenetic IAP-Dependent Protein Eraser (SNIPER) von Ohoka, Nobumichi, Ujikawa, Osamu, Shimokawa, Kenichiro, Sameshima, Tomoya, Shibata, Norihito, Hattori, Takayuki, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko

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Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand von Demizu, Yosuke, Shibata, Norihito, Hattori, Takayuki, Ohoka, Nobumichi, Motoi, Hiromi, Misawa, Takashi, Shoda, Takuji, Naito, Mikihiko, Kurihara, Masaaki

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Degradation of HaloTag-fused nuclear proteins using bestatin-HaloTag ligand hybrid molecules von Tomoshige, Shusuke, Naito, Mikihiko, Hashimoto, Yuichi, Ishikawa, Minoru

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Design, synthesis and biological evaluation of nuclear receptor-degradation inducers von Itoh, Yukihiro, Kitaguchi, Risa, Ishikawa, Minoru, Naito, Mikihiko, Hashimoto, Yuichi

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Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells von Shibata, Norihito, Ohoka, Nobumichi, Tsuji, Genichiro, Demizu, Yosuke, Miyawaza, Keiji, Ui-Tei, Kumiko, Akiyama, Tetsu, Naito, Mikihiko

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Development of 2-aminoisobutyric acid (Aib)-rich cell-penetrating foldamers for efficient siRNA delivery von Misawa, Takashi, Ohoka, Nobumichi, Oba, Makoto, Yamashita, Hiroko, Tanaka, Masakazu, Naito, Mikihiko, Demizu, Yosuke

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SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib von Ohoka, Nobumichi, Nagai, Katsunori, Shibata, Norihito, Hattori, Takayuki, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko

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Targeted Protein Degradation by Chimeric Small Molecules, PROTACs and SNIPERs von Naito, Mikihiko, Ohoka, Nobumichi, Shibata, Norihito, Tsukumo, Yoshinori

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Development of hybrid small molecules that induce degradation of estrogen receptor‐alpha and necrotic cell death in breast cancer cells von Okuhira, Keiichiro, Demizu, Yosuke, Hattori, Takayuki, Ohoka, Nobumichi, Shibata, Norihito, Nishimaki‐Mogami, Tomoko, Okuda, Haruhiro, Kurihara, Masaaki, Naito, Mikihiko

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Selective Degradation of Target Proteins by Chimeric Small-Molecular Drugs, PROTACs and SNIPERs von Ishikawa, Minoru, Tomoshige, Shusuke, Demizu, Yosuke, Naito, Mikihiko

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Hybrid molecule between platanic acid and LCL-161 as a yes-associated protein degrader von Nakano, Naoko, Fukuda, Kazuo, Tashiro, Etsu, Ishikawa, Haruka, Nagano, Waka, Kawamoto, Rie, Mori, Alice, Watanabe, Misao, Yamazaki, Ryu, Nakane, Takahisa, Naito, Mikihiko, Okamoto, Iwao, Itoh, Susumu

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Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal von Tsuruo, Takashi, Naito, Mikihiko, Tomida, Akihiro, Fujita, Naoya, Mashima, Tetsuo, Sakamoto, Hiroshi, Haga, Naomi

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