Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process von Du, Jun, Suzuki, Haruhiko, Nagase, Fumihiko, Akhand, Anwarul A, Ma, Xiu-Yang, Yokoyama, Toshihiro, Miyata, Toshio, Nakashima, Izumi

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High-affinity uptake of kynurenine and nitric oxide-mediated inhibition of indoleamine 2,3-dioxygenase in bone marrow-derived myeloid dendritic cells von Hara, Toshiaki, Ogasawara, Nanako, Akimoto, Hidetoshi, Takikawa, Osamu, Hiramatsu, Rie, Kawabe, Tsutomu, Isobe, Ken-ichi, Nagase, Fumihiko

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Binding activity of H-Ras is necessary for in vivo inhibition of ASK1 activity von DU, Jun, CAI, Shao Hui, SHI, Zhe, NAGASE, Fumihiko

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Phorbol 12-Myristate 13-Acetate Protects Jurkat Cells from Methylglyoxal-Induced Apoptosis by Preventing c-Jun N-Terminal Kinase-Mediated Leakage of Cytochrome c in an Extracellula... von Takagi, Yoshikazu, Du, Jun, Ma, Xiu-Yang, Nakashima, Izumi, Nagase, Fumihiko

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Involvement of MEKK1/ERK/P21Waf1/Cip1 signal transduction pathway in inhibition of IGF-I-mediated cell growth response by methylglyoxal von Du, Jun, Cai, Shaohui, Suzuki, Haruhiko, Akhand, Anwarul A., Ma, Xiuyang, Takagi, Yoshikazu, Miyata, Toshio, Nakashima, Izumi, Nagase, Fumihiko

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Hemoglobin induces the expression of indoleamine 2,3-dioxygenase in dendritic cells through the activation of PI3K, PKC, and NF-κB and the generation of reactive oxygen species von Ogasawara, Nanako, Oguro, Takashi, Sakabe, Toshitsugu, Matsushima, Miyoko, Takikawa, Osamu, Isobe, Ken-ichi, Nagase, Fumihiko

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Cinnabarinic acid generated from 3-hydroxyanthranilic acid strongly induces apoptosis in thymocytes through the generation of reactive oxygen species and the induction of caspase von Hiramatsu, Rie, Hara, Toshiaki, Akimoto, Hidetoshi, Takikawa, Osamu, Kawabe, Tsutomu, Isobe, Ken-ichi, Nagase, Fumihiko

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Characterization of the Immunoregulatory Action of Saikosaponin-d von Kato, Masashi, Pu, Mei-Yi, Isobe, Ken-Ichi, Iwamoto, Takashi, Nagase, Fumihiko, Lwin, Tint, Zhang, Yue-Hua, Hattori, Taku, Yanagita, Noriyuki, Nakashima, Izumi

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Methylglyoxal induces apoptosis in Jurkat leukemia T cells by activating c-Jun N-Terminal kinase von Du, Jun, Suzuki, Haruhiko, Nagase, Fumihiko, Akhand, Anwarul A., Yokoyama, Toshihiro, Miyata, Toshio, Kurokawa, Kiyoshi, Nakashima, Izumi

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Diazotization of kynurenine by acidified nitrite secreted from indoleamine 2,3-dioxygenase-expressing myeloid dendritic cells von Hara, Toshiaki, Yamakura, Fumiyuki, Takikawa, Osamu, Hiramatsu, Rie, Kawabe, Tsutomu, Isobe, Ken-ichi, Nagase, Fumihiko

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Induction of Apoptosis and Tyrosine Phosphorylation of Cellular Proteins in T Cells and Non-T Cells by Stimulation with Concanavalin A von Nagase, Fumihiko, Abo, Tomoko, Hiramatsu, Kumiko, Suzuki, Shin-ichi, Du, Jun, Nakashima, Izumi

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Cytokine-Independent Proliferation of IL-2-Nonproducing CTL Clones in Association with High TCR-Signal Transduction Responses von Nagase, Fumihiko, Lwin, Tint, Nakashima, Izumi

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TCR-Independent Induction of Low Responsiveness by Chemically Fixed Cells in Alloreactive CTL Clones and Its Prevention through Cognate Cell-Cell Interaction von Lwin, Tint, Nakashima, Izumi, Nagase, Fumihiko

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Down-Regulation of T-Cell Proliferation in Response to Soluble Anti-CD3 Antibodies through Development of Redirected Cytolytic Activity Eliminating Costimulatory Cells von Lwin, Tint, Nakashima, Izumi, Nagase, Fumihiko

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Redox-linked cell surface-oriented signaling for T-cell death von Akhand, Anwarul A, Du, Jun, Liu, Wei, Hossain, Khaled, Miyata, Toshio, Nagase, Fumihiko, Kato, Masashi, Suzuki, Haruhiko, Nakashima, Izumi

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Menadione biphasically controls JNK-linked cell death in leukemia Jurkat T cells von Ma, Xiuyang, Du, Jun, Nakashima, Izumi, Nagase, Fumihiko

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Hemoglobin induces the expression of indoleamine 2,3-dioxygenase in dendritic cells through the activation of PI3K, PKC, and NF-kappaB and the generation of reactive oxygen species von Ogasawara, Nanako, Oguro, Takashi, Sakabe, Toshitsugu, Matsushima, Miyoko, Takikawa, Osamu, Isobe, Ken-ichi, Nagase, Fumihiko

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Expression of chimeric receptor composed of immunoglobulin-derived V resions and T-cell receptor-derived C regions von Kuwana, Yoshihisa, Asakura, Yoshihiro, Utsunomiya, Naoko, Nakanishi, Mamoru, Arata, Yohji, Itoh, Seiga, Nagase, Fumihiko, Kurosawa, Yoshikazu

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Enhancement of 3-hydroxyanthranilic acid-induced T cell apoptosis through cinnabarinic acid generation von Hiramatsu, Rie, Hara, Toshiaki, Akimoto, Hidetoshi, Takikawa, Osamu, Kawabe, Tsutomu, Nagase, Fumihiko

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Involvement of MEKK1/ERK/P21 Waf1/Cip1 signal transduction pathway in inhibition of IGF‐I‐mediated cell growth response by methylglyoxal von Du, Jun, Cai, Shaohui, Suzuki, Haruhiko, Akhand, Anwarul A., Ma, Xiuyang, Takagi, Yoshikazu, Miyata, Toshio, Nakashima, Izumi, Nagase, Fumihiko

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