Malonyl Coenzyme A Decarboxylase Inhibition Protects the Ischemic Heart by Inhibiting Fatty Acid Oxidation and Stimulating Glucose Oxidation von Dyck, Jason R.B, Cheng, Jie-Fei, Stanley, William C, Barr, Rick, Chandler, Margaret P, Brown, Steven, Wallace, David, Arrhenius, Thomas, Harmon, Charles, Yang, Guang, Nadzan, Alex M, Lopaschuk, Gary D

Volltext

Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists von Mukherjee, Ranjan, Davies, Peter J. A, Crombie, Diane L, Bischoff, Eric D, Cesario, Rosemary M, Jow, Lily, Hamann, Lawrence G, Boehm, Marcus F, Mondon, Carl E, Nadzan, Alex M, Paterniti, James R, Heyman, Richard A

Volltext

Discovery of Potent and Orally Available Malonyl-CoA Decarboxylase Inhibitors as Cardioprotective Agents von Cheng, Jie-Fei, Huang, Yujin, Penuliar, Richard, Nishimoto, Masahiro, Liu, Larry, Arrhenius, Thomas, Yang, Guang, O'Leary, Eoin, Barbosa, Miguel, Barr, Rick, Dyck, Jason R. B, Lopaschuk, Gary D, Nadzan, Alex M

Volltext

Activation of specific RXR heterodimers by an antagonist of RXR homodimers von Lala, Deepak S, Mukherjee, Ranjan, Schulman, Ira G, Koch, Stacie S. Canan, Dardashti, Laura J, Nadzan, Alex M, Croston, Glenn E, Evans, Ronald M, Heyman, Richard A

Volltext

Identification of the First Retinoid X Receptor Homodimer Antagonist von Canan Koch, Stacie S, Dardashti, Laura J, Hebert, Jonathan J, White, Steven K, Croston, Glenn E, Flatten, Karen S, Heyman, Richard A, Nadzan, Alex M

Volltext

Design and Synthesis of Potent Retinoid X Receptor Selective Ligands That Induce Apoptosis in Leukemia Cells von Boehm, Marcus F, Zhang, Lin, Zhi, Lin, McClurg, Michael R, Berger, Elain, Wagoner, Murriel, Mais, Dale E, Suto, Carla M, Davies, Peter J. A, Heyman, Richard A, Nadzan, Alex M

Volltext

Synthesis and Structure−Activity Relationship of Small-Molecule Malonyl Coenzyme A Decarboxylase Inhibitors von Cheng, Jie-Fei, Chen, Mi, Wallace, David, Tith, Souvothy, Haramura, Masayuki, Liu, Bin, Mak, Chi Ching, Arrhenius, Thomas, Reily, Sean, Brown, Steven, Thorn, Vicki, Harmon, Charles, Barr, Rick, Dyck, Jason R. B, Lopaschuk, Gary D, Nadzan, Alex M

Volltext

Novel trifluoroacetophenone derivatives as malonyl-CoA decarboxylase inhibitors von Wallace, David M., Haramura, Masayuki, Cheng, Jie-Fei, Arrhenius, Thomas, Nadzan, Alex M.

Volltext

Design and synthesis of heterocyclic malonyl-CoA decarboxylase inhibitors von Cheng, Jie-Fei, Chen, Mi, Liu, Bin, Hou, Zheng, Arrhenius, Thomas, Nadzan, Alex M.

Volltext

Synthesis of Retinoid X Receptor-Specific Ligands That Are Potent Inducers of Adipogenesis in 3T3-L1 Cells von Canan Koch, Stacie S, Dardashti, Laura J, Cesario, Rosemary M, Croston, Glenn E, Boehm, Marcus F, Heyman, Richard A, Nadzan, Alex M

Volltext

Aza-retinoids as novel retinoid X receptor-specific agonists von Farmer, Luc J., Marron, Kristen S., Canan Koch, Stacie S., Hwang, C.K., Kallel, E Adam, Zhi, Lin, Nadzan, Alex M., Robertson, Dave W., Bennani, Youssef L.

Volltext

Heteroaryl substituted bis-trifluoromethyl carbinols as malonyl-CoA decarboxylase inhibitors von Cheng, Jie-Fei, Mak, Chi Ching, Huang, Yujin, Penuliar, Richard, Nishimoto, Masahiro, Zhang, Lin, Chen, Mi, Wallace, David, Arrhenius, Thomas, Chu, Donald, Yang, Guang, Barbosa, Miguel, Barr, Rick, Dyck, Jason R.B., Lopaschuk, Gary D., Nadzan, Alex M.

Volltext

Conformationally constrained amino acids. Synthesis and optical resolution of 3-substituted proline derivatives von Chung, John Y. L, Wasicak, James T, Arnold, William A, May, Catherine S, Nadzan, Alex M, Holladay, Mark W

Volltext

Retinoic acid receptor ligands based on the 6-cyclopropyl-2,4-hexadienoic acid von Farmer, Luc J., Zhi, Lin, Jeong, Susan, Lamph, William W., Osburn, Deborah L., Croston, Glenn, Flatten, Karen S., Heyman, Rich A., Nadzan, Alex M.

Volltext

Expression, purification, and characterization of human malonyl-CoA decarboxylase von Zhou, Demin, Yuen, Phoebe, Chu, Donald, Thon, Vicki, McConnell, Steve, Brown, Steven, Tsang, Andria, Pena, Michael, Russell, Anna, Cheng, Jie-Fei, Nadzan, Alex M., Barbosa, Miguel S., Dyck, Jason R.B., Lopaschuk, Gary D., Yang, Guang

Volltext

A novel retinoic acid receptor-selective retinoid, ALRT1550, has potent antitumor activity against human oral squamous carcinoma xenografts in nude mice von SHALINSKY, D. R, BISCHOFF, E. D, LAMPH, W. W, ZHANG, L, BOEHM, M. F, DAVIES, P. J. A, NADZAN, A. M, HEYMAN, R. A

Volltext

Hybrid cholecystokinin (CCK) antagonists: new implications in the design and modification of CCK antagonists von Kerwin, James F, Nadzan, Alex M, Kopecka, Hana, Lin, Chun Wel, Miller, Thomas, Witte, David, Burt, Stanley

Volltext

The Intracellular Receptor and Signal Transducers and Activators of Transcription Factor Superfamilies: Novel Targets for Small-Molecule Drug Discovery von Rosen, Jonathan, Day, Adrienne, Jones, Todd K, Jones, E. Tracy Turner, Nadzan, Alex M, Stein, Robert B

Volltext

Discovery of Novel Retinoic Acid Receptor Agonists Having Potent Antiproliferative Activity in Cervical Cancer Cells von Zhang, Lin, Nadzan, Alex M, Heyman, Richard A, Love, Deborah L, Mais, Dale E, Croston, Glenn, Lamph, William W, Boehm, Marcus F

Volltext

Synthesis of .alpha.-benzyl .gamma.-lactam, .alpha.-benzyl .delta.-lactam, and .alpha.-benzylproline derivatives as conformationally restricted analogs of phenylalaninamide von Holladay, Mark W, Nadzan, Alex M

Volltext