Regulation of Tissue Inflammation by 12-Lipoxygenases von Kulkarni, Abhishek, Nadler, Jerry L, Mirmira, Raghavendra G, Casimiro, Isabel

Volltext

Eliminating or blocking 12/15-lipoxygenase reduces neutrophil recruitment in mouse models of acute lung injury von Rossaint, Jan, Nadler, Jerry L, Ley, Klaus, Zarbock, Alexander

Volltext

Functional and pathological roles of the 12- and 15-lipoxygenases von Dobrian, Anca D., Lieb, David C., Cole, Banumathi K., Taylor-Fishwick, David A., Chakrabarti, Swarup K., Nadler, Jerry L.

Volltext

Interleukin-12 (IL-12)/STAT4 Axis Is an Important Element for β-Cell Dysfunction Induced by Inflammatory Cytokines von Weaver, Jessica R, Nadler, Jerry L, Taylor-Fishwick, David A

Volltext

Macrophage-specific lipoxygenase deletion amplify cardiac repair activating Treg cells in chronic heart failure von Kain, Vasundhara, Grilo, Gabriel Araujo, Upadhyay, Gunjan, Nadler, Jerry L, Serhan, Charles N, Halade, Ganesh V

Volltext

Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease von Uderhardt, Stefan, Ackermann, Jochen A, Fillep, Tobias, Hammond, Victoria J, Willeit, Johann, Santer, Peter, Mayr, Manuel, Biburger, Markus, Miller, Meike, Zellner, Katie R, Stark, Konstantin, Zarbock, Alexander, Rossaint, Jan, Schubert, Irene, Mielenz, Dirk, Dietel, Barbara, Raaz-Schrauder, Dorette, Ay, Cihan, Gremmel, Thomas, Thaler, Johannes, Heim, Christian, Herrmann, Martin, Collins, Peter W, Schabbauer, Gernot, Mackman, Nigel, Voehringer, David, Nadler, Jerry L, Lee, James J, Massberg, Steffen, Rauh, Manfred, Kiechl, Stefan, Schett, Georg, O'Donnell, Valerie B, Krönke, Gerhard

Volltext

Lipid Inflammatory Mediators in Diabetic Vascular Disease von Natarajan, Rama, Nadler, Jerry L

Volltext

Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes von Nyalwidhe, Julius O, Grzesik, Wojciech J, Burch, Tanya C, Semeraro, Michele L, Waseem, Tayab, Gerling, Ivan C, Mirmira, Raghavendra G, Morris, Margaret A, Nadler, Jerry L

Volltext

Proteomic Analysis of Disease Stratified Human Pancreas Tissue Indicates Unique Signature of Type 1 Diabetes von Burch, Tanya C, Morris, Margaret A, Campbell-Thompson, Martha, Pugliese, Alberto, Nadler, Jerry L, Nyalwidhe, Julius O

Volltext

Expression Pattern of 12-Lipoxygenase in Human Islets With Type 1 Diabetes and Type 2 Diabetes von Grzesik, Wojciech J, Nadler, Joseph L, Machida, Yui, Nadler, Jerry L, Imai, Yumi, Morris, Margaret A

Volltext

12/15-Lipoxygenase Products Induce Inflammation and Impair Insulin Signaling in 3T3-L1 Adipocytes von Chakrabarti, Swarup K., Cole, Banumathi K., Wen, Yeshao, Keller, Susanna R., Nadler, Jerry L.

Volltext

Lipids and immunoinflammatory pathways of beta cell destruction von Imai, Yumi, Dobrian, Anca D., Morris, Margaret A., Taylor-Fishwick, David A., Nadler, Jerry L.

Volltext

Docking and mutagenesis studies lead to improved inhibitor development of ML355 for human platelet 12-lipoxygenase von Tsai, Wan-Chen, Aleem, Ansari M., Tena, Jennyfer, Rivera-Velazquez, Mirella, Brah, Harman Singh, Tripathi, Sarvind, D'silva, Melinee, Nadler, Jerry L., Kalyanaraman, Chakrapani, Jacobson, Matthew P., Holman, Theodore

Volltext

Complement Activation and STAT4 Expression Are Associated with Early Inflammation in Diabetic Wounds von Cunnion, Kenji M, Krishna, Neel K, Pallera, Haree K, Pineros-Fernandez, Angela, Rivera, Magdielis Gregory, Hair, Pamela S, Lassiter, Brittany P, Huyck, Ryan, Clements, Mary A, Hood, Antoinette F, Rodeheaver, George T, Cottler, Patrick S, Nadler, Jerry L, Dobrian, Anca D

Volltext

Neutrophil-specific STAT4 deficiency attenuates atherosclerotic burden and improves plaque stability via reduction in neutrophil activation and recruitment into aortas of Ldlr -/-... von Keeter, W Coles, Moriarty, Alina K, Akers, Rachel, Ma, Shelby, Mussbacher, Marion, Nadler, Jerry L, Galkina, Elena V

Volltext

STAT4 Play A Critical Role in Aging and High Fat Diet‐Associated Decline in Long‐Term, Activity‐Dependent Potentiation of Synaptic Transmission von Stanton, Patric K., Nadler, Jerry L., Zhang, Xiao‐lei, Hollander, Callie, Ma, Haoqin, Yang, Xinyuan, D’silva, Melinee, Stahr, Natalie, Moriarty, Alina, Keeter, Coles, Galkina, Elena V.

Volltext

5-Lipoxygenase, but Not 12/15-Lipoxygenase, Contributes to Degeneration of Retinal Capillaries in a Mouse Model of Diabetic Retinopathy von GUBITOSI-KLUG, Rose A, TALAHALLI, Ramaprasad, YUNPENG DU, NADLER, Jerry L, KERN, Timothy S

Volltext

Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative–nitrosative stress and p38 MAPK activation von Stavniichuk, Roman, Drel, Viktor R., Shevalye, Hanna, Maksimchyk, Yury, Kuchmerovska, Tamara M., Nadler, Jerry L., Obrosova, Irina G.

Volltext

Inflammatory mechanisms of diabetic complications von Williams, Michael D, Nadler, Jerry L

Volltext

Inhibition of 12/15-Lipoxygenase Protects Against β-Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes von Hernandez-Perez, Marimar, Chopra, Gaurav, Fine, Jonathan, Conteh, Abass M, Anderson, Ryan M, Linnemann, Amelia K, Benjamin, Chanelle, Nelson, Jennifer B, Benninger, Kara S, Nadler, Jerry L, Maloney, David J, Tersey, Sarah A, Mirmira, Raghavendra G

Volltext