The PCSK9 discovery, an inactive protease with varied functions in hypercholesterolemia, viral infections, and cancer von Seidah, Nabil G.

Volltext

The biology and therapeutic targeting of the proprotein convertases von Seidah, Nabil G., Prat, Annik

Volltext

The Multifaceted Biology of PCSK9 von Seidah, Nabil G, Prat, Annik

Volltext

Proprotein convertase subtilisin/kexin type 9 (PCSK9) can mediate degradation of the low density lipoprotein receptor-related protein 1 (LRP-1) von Canuel, Maryssa, Sun, Xiaowei, Asselin, Marie-Claude, Paramithiotis, Eustache, Prat, Annik, Seidah, Nabil G

Volltext

PCSK9: A Key Modulator of Cardiovascular Health von Seidah, Nabil G, Awan, Zuhier, Chrétien, Michel, Mbikay, Majambu

Volltext

Expanding Biology of PCSK9: Roles in Atherosclerosis and Beyond von Seidah, Nabil G., Garçon, Damien

Volltext

New developments in proprotein convertase subtilisin–kexin 9's biology and clinical implications von Seidah, Nabil G.

Volltext

The Proprotein Convertases in Hypercholesterolemia and Cardiovascular Diseases: Emphasis on Proprotein Convertase Subtilisin/Kexin 9 von Seidah, Nabil G, Abifadel, Marianne, Prost, Stefan, Boileau, Catherine, Prat, Annik

Volltext

Novel strategies to target proprotein convertase subtilisin kexin 9: beyond monoclonal antibodies von Seidah, Nabil G, Prat, Annik, Pirillo, Angela, Catapano, Alberico Luigi, Norata, Giuseppe Danilo

Volltext

The Elusive Inhibitory Function of the Acidic N-Terminal Segment of the Prodomain of PCSK9: The Plot Thickens von Seidah, Nabil G.

Volltext

Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models von Kim, Kyeongdae, Shim, Dahee, Lee, Jun Seong, Zaitsev, Konstantin, Williams, Jesse W, Kim, Ki-Wook, Jang, Man-Young, Seok Jang, Hyung, Yun, Tae Jin, Lee, Seung Hyun, Yoon, Won Kee, Prat, Annik, Seidah, Nabil G, Choi, Jungsoon, Lee, Seung-Pyo, Yoon, Sang-Ho, Nam, Jin Wu, Seong, Je Kyung, Oh, Goo Taeg, Randolph, Gwendalyn J, Artyomov, Maxim N, Cheong, Cheolho, Choi, Jae-Hoon

Volltext

What lies ahead for the proprotein convertases? von Seidah, Nabil G.

Volltext

Lipoprotein(a) Catabolism Is Regulated by Proprotein Convertase Subtilisin/Kexin Type 9 through the Low Density Lipoprotein Receptor von Romagnuolo, Rocco, Scipione, Corey A., Boffa, Michael B., Marcovina, Santica M., Seidah, Nabil G., Koschinsky, Marlys L.

Volltext

How Do Enveloped Viruses Exploit the Secretory Proprotein Convertases to Regulate Infectivity and Spread? von Seidah, Nabil G., Pasquato, Antonella, Andréo, Ursula

Volltext

Cleavage of a Neuroinvasive Human Respiratory Virus Spike Glycoprotein by Proprotein Convertases Modulates Neurovirulence and Virus Spread within the Central Nervous System von Le Coupanec, Alain, Desforges, Marc, Meessen-Pinard, Mathieu, Dubé, Mathieu, Day, Robert, Seidah, Nabil G, Talbot, Pierre J

Volltext

Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity von Essalmani, Rachid, Jain, Jaspreet, Susan-Resiga, Delia, Andréo, Ursula, Evagelidis, Alexandra, Derbali, Rabeb Mouna, Huynh, David N, Dallaire, Frédéric, Laporte, Mélanie, Delpal, Adrien, Sutto-Ortiz, Priscila, Coutard, Bruno, Mapa, Claudine, Wilcoxen, Keith, Decroly, Etienne, Nq Pham, Tram, Cohen, Éric A, Seidah, Nabil G

Volltext

Gene Inactivation of Proprotein Convertase Subtilisin/Kexin Type 9 Reduces Atherosclerosis in Mice von DENIS, Maxime, MARCINKIEWICZ, Jadwiga, ZAID, Ahmed, GAUTHIER, Dany, POIRIER, Steve, LAZURE, Claude, SEIDAH, Nabil G, PRAT, Annik

Volltext

Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation von Seidah, Nabil G, Poirier, Steve, Denis, Maxime, Parker, Rex, Miao, Bowman, Mapelli, Claudio, Prat, Annik, Wassef, Hanny, Davignon, Jean, Hajjar, Katherine A, Mayer, Gaétan

Volltext

Processing of Human Toll-like Receptor 7 by Furin-like Proprotein Convertases Is Required for Its Accumulation and Activity in Endosomes von Hipp, Madeleine M., Shepherd, Dawn, Gileadi, Uzi, Aichinger, Michael C., Kessler, Benedikt M., Edelmann, Mariola J., Essalmani, Rachid, Seidah, Nabil G., Reis e Sousa, Caetano, Cerundolo, Vincenzo

Volltext

PCSK9 as a therapeutic target of dyslipidemia von Seidah, Nabil G

Volltext