MicroRNAs in metabolism and metabolic disorders von Rottiers, Veerle, Näär, Anders M.

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SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait von Wu, Su, Näär, Anders M.

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SIRT6 Recruits SNF2H to DNA Break Sites, Preventing Genomic Instability through Chromatin Remodeling von Toiber, Debra, Erdel, Fabian, Bouazoune, Karim, Silberman, Dafne M., Zhong, Lei, Mulligan, Peter, Sebastian, Carlos, Cosentino, Claudia, Martinez-Pastor, Barbara, Giacosa, Sofia, D’Urso, Agustina, Näär, Anders M., Kingston, Robert, Rippe, Karsten, Mostoslavsky, Raul

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A lipid-free and insulin-supplemented medium supports De Novo fatty acid synthesis gene activation in melanoma cells von Wu, Su, Näär, Anders M

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miR-33: A Metabolic Conundrum von Näär, Anders M.

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A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans von Walker, Amy K., Jacobs, René L., Watts, Jennifer L., Rottiers, Veerle, Jiang, Karen, Finnegan, Deirdre M., Shioda, Toshi, Hansen, Malene, Yang, Fajun, Niebergall, Lorissa J., Vance, Dennis E., Tzoneva, Monika, Hart, Anne C., Näär, Anders M.

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Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression von Hancock, Melissa L., Meyer, Rebecca C., Mistry, Meeta, Khetani, Radhika S., Wagschal, Alexandre, Shin, Taehwan, Ho Sui, Shannan J., Näär, Anders M., Flanagan, John G.

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An intranasal ASO therapeutic targeting SARS-CoV-2 von Zhu, Chi, Lee, Justin Y., Woo, Jia Z., Xu, Lei, Nguyenla, Xammy, Yamashiro, Livia H., Ji, Fei, Biering, Scott B., Van Dis, Erik, Gonzalez, Federico, Fox, Douglas, Wehri, Eddie, Rustagi, Arjun, Pinsky, Benjamin A., Schaletzky, Julia, Blish, Catherine A., Chiu, Charles, Harris, Eva, Sadreyev, Ruslan I., Stanley, Sarah, Kauppinen, Sakari, Rouskin, Silvi, Näär, Anders M.

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MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels von Goedeke, Leigh, Rotllan, Noemi, Canfrán-Duque, Alberto, Aranda, Juan F, Ramírez, Cristina M, Araldi, Elisa, Lin, Chin-Sheng, Anderson, Norma N, Wagschal, Alexandre, de Cabo, Rafael, Horton, Jay D, Lasunción, Miguel A, Näär, Anders M, Suárez, Yajaira, Fernández-Hernando, Carlos

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SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling von Biering, Scott B., Gomes de Sousa, Francielle Tramontini, Tjang, Laurentia V., Pahmeier, Felix, Zhu, Chi, Ruan, Richard, Blanc, Sophie F., Patel, Trishna S., Worthington, Caroline M., Glasner, Dustin R., Castillo-Rojas, Bryan, Servellita, Venice, Lo, Nicholas T. N., Wong, Marcus P., Warnes, Colin M., Sandoval, Daniel R., Clausen, Thomas Mandel, Santos, Yale A., Fox, Douglas M., Ortega, Victoria, Näär, Anders M., Baric, Ralph S., Stanley, Sarah A., Aguilar, Hector C., Esko, Jeffrey D., Chiu, Charles Y., Pak, John E., Beatty, P. Robert, Harris, Eva

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A nuclear receptor-like pathway regulating multidrug resistance in fungi von Thakur, Jitendra K., Arthanari, Haribabu, Yang, Fajun, Pan, Shih-Jung, Fan, Xiaochun, Breger, Julia, Frueh, Dominique P., Gulshan, Kailash, Li, Darrick K., Mylonakis, Eleftherios, Struhl, Kevin, Moye-Rowley, W. Scott, Cormack, Brendan P., Wagner, Gerhard, Näär, Anders M.

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A SIRT1-LSD1 Corepressor Complex Regulates Notch Target Gene Expression and Development von Mulligan, Peter, Yang, Fajun, Di Stefano, Luisa, Ji, Jun-Yuan, Ouyang, Jian, Nishikawa, Joy L., Toiber, Debra, Kulkarni, Madhura, Wang, Qun, Najafi-Shoushtari, S. Hani, Mostoslavsky, Raul, Gygi, Steven P., Gill, Grace, Dyson, Nicholas J., Näär, Anders M.

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The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis von Hong, Xin, Roh, Whijae, Sullivan, Ryan J, Wong, Keith H K, Wittner, Ben S, Guo, Hongshan, Dubash, Taronish D, Sade-Feldman, Moshe, Wesley, Benjamin, Horwitz, Elad, Boland, Genevieve M, Marvin, Dieuwke L, Bonesteel, Todd, Lu, Chenyue, Aguet, François, Burr, Risa, Freeman, Samuel S, Parida, Laxmi, Calhoun, Katherine, Jewett, Michelle K, Nieman, Linda T, Hacohen, Nir, Näär, Anders M, Ting, David T, Toner, Mehmet, Stott, Shannon L, Getz, Gad, Maheswaran, Shyamala, Haber, Daniel A

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miRNA regulation of LDL-cholesterol metabolism von Goedeke, Leigh, Wagschal, Alexandre, Fernández-Hernando, Carlos, Näär, Anders M.

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Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP von Walker, Amy K, Yang, Fajun, Jiang, Karen, Ji, Jun-Yuan, Watts, Jennifer L, Purushotham, Aparna, Boss, Olivier, Hirsch, Michael L, Ribich, Scott, Smith, Jesse J, Israelian, Kristine, Westphal, Christoph H, Rodgers, Joseph T, Shioda, Toshi, Elson, Sarah L, Mulligan, Peter, Najafi-Shoushtari, Hani, Black, Josh C, Thakur, Jitendra K, Kadyk, Lisa C, Whetstine, Johnathan R, Mostoslavsky, Raul, Puigserver, Pere, Li, Xiaoling, Dyson, Nicholas J, Hart, Anne C, Näär, Anders M

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An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis von Yang, Fajun, Vought, Bryan W., Satterlee, John S., Walker, Amy K., Jim Sun, Z.-Y., Watts, Jennifer L., DeBeaumont, Rosalie, Mako Saito, R., Hyberts, Sven G., Yang, Shaosong, Macol, Christine, Iyer, Lakshmanan, Tjian, Robert, van den Heuvel, Sander, Hart, Anne C., Wagner, Gerhard, Näär, Anders M.

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Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence von Sedic, Maja, Skibinski, Adam, Brown, Nelson, Gallardo, Mercedes, Mulligan, Peter, Martinez, Paula, Keller, Patricia J., Glover, Eugene, Richardson, Andrea L., Cowan, Janet, Toland, Amanda E., Ravichandran, Krithika, Riethman, Harold, Naber, Stephen P., Näär, Anders M., Blasco, Maria A., Hinds, Philip W., Kuperwasser, Charlotte

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MicroRNA-33 Regulates the Innate Immune Response via ATP Binding Cassette Transporter-mediated Remodeling of Membrane Microdomains von Lai, Lihua, Azzam, Kathleen M., Lin, Wan-Chi, Rai, Prashant, Lowe, Julie M., Gabor, Kristin A., Madenspacher, Jennifer H., Aloor, Jim J., Parks, John S., Näär, Anders M., Fessler, Michael B.

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Targeting of miR-33 ameliorates phenotypes linked to age-related macular degeneration von Gnanaguru, Gopalan, Wagschal, Alexandre, Oh, Justin, Saez-Torres, Kahira L., Li, Tong, Temel, Ryan E., Kleinman, Mark E., Näär, Anders M., D’Amore, Patricia A.

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A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening von Gorgulla, Christoph, Padmanabha Das, Krishna M., Leigh, Kendra E., Cespugli, Marco, Fischer, Patrick D., Wang, Zi-Fu, Tesseyre, Guilhem, Pandita, Shreya, Shnapir, Alec, Calderaio, Anthony, Gechev, Minko, Rose, Alexander, Lewis, Noam, Hutcheson, Colin, Yaffe, Erez, Luxenburg, Roni, Herce, Henry D., Durmaz, Vedat, Halazonetis, Thanos D., Fackeldey, Konstantin, Patten, J.J., Chuprina, Alexander, Dziuba, Igor, Plekhova, Alla, Moroz, Yurii, Radchenko, Dmytro, Tarkhanova, Olga, Yavnyuk, Irina, Gruber, Christian, Yust, Ryan, Payne, Dave, Näär, Anders M., Namchuk, Mark N., Davey, Robert A., Wagner, Gerhard, Kinney, Jamie, Arthanari, Haribabu

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