First Clinical Application of an Actively Reversible Direct Factor IXa Inhibitor as an Anticoagulation Strategy in Patients Undergoing Percutaneous Coronary Intervention von COHEN, Mauricio G, PURDY, Drew A, ZELENKOFSKE, Steven, ALEXANDER, John H, HARRINGTON, Robert A, RUSCONI, Christopher P, BECKER, Richard C, ROSSI, Joseph S, GRINFELD, Liliana R, MYLES, Shelley K, ABERLE, Laura H, GREENBAUM, Adam B, FRY, Edward, CHAN, Mark Y, TONKENS, Ross M

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First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology : A phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled re... von DYKE, Christopher K, STEINHUBL, Steven R, BECKER, Richard C, RUSCONI, Christopher P, KLEIMAN, Neal S, CANNON, Richard O, ABERLE, Laura G, MIN LIN, MYLES, Shelley K, MELLONI, Chiara, HARRINGTON, Robert A, ALEXANDER, John H

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Phase 1b Randomized Study of Antidote-Controlled Modulation of Factor IXa Activity in Patients With Stable Coronary Artery Disease von CHAN, Mark Y, COHEN, Mauricio G, VORCHHEIMER, David A, CHRONOS, Nicholas, MELLONI, Chiara, ALEXANDER, John H, HARRINGTON, Robert A, TONKENS, Ross M, BECKER, Richard C, RUSCONI, Christopher P, DYKE, Christopher K, MYLES, Shelley K, ABERLE, Laura G, MIN LIN, WALDER, James, STEINHUBL, Steven R, GILCHRIST, Ian C, KLEIMAN, Neal S

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FACTOR IXA INHIBITION WITH REG1 PROVIDES RAPID ONSET, STABLE AND ACTIVELY CONTROLLED ANTICOAGULATION DURING PCI von Cohen, Mauricio G, Purdy, Drew A, Rossi, Joseph S, Grinfeld, Liliana R, Myles, Shelley K, Aberle, Laura H, Greenbaum, Adam B, Fry, Edward, Chan, Mark Y, Zelenkofske, Steven, Alexander, John H, Harrington, Robert A, Rusconi, Christopher P, Becker, Richard C

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Abstract 2780: A First-in-Class Oligonucleotide Drug-Antidote Pair Efficiently Modulates Factor IXa Activity in Human Subjects - A Nascent Platform for Antidote-Controlled Periproc... von Chan, Mark Y, Cohen, Mauricio G, Rusconi, Christopher P, Alexander, John H, Myles, Shelley K, Aberle, Laura G, Lin, Min, Melloni, Chiara, Tonkens, Ross M, Harrington, Robert A, Becker, Richard C

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Evaluation of a New Heparin Agent in Percutaneous Coronary Intervention Results of the Phase 2 Evaluation of M118 IN pErcutaNeous Coronary intErvention (EMINENCE) Trial von RAO, Sunil V, MELLONI, Chiara, RIVERA, Ernesto, ALEXANDER, John H, FIER, Ian, ROACH, James, BECKER, Richard C, MYLES-DIMAURO, Shelley, BRODERICK, Samuel, KOSINSKI, Andrzej S, KLEIMAN, Neal S, DZAVIK, Vladimir, TANGUAY, Jean Francois, CHANDNA, Harish, GAMMON, Roger

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