Spatial profiling of endoplasmic reticulum stress markers in tumor associated cells predicts patient outcomes in pancreatic cancer von Porter, Georgia, Norris, Murray, Apte, Minoti, Merlot, Angelica

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ABC transporters in cancer: more than just drug efflux pumps von Fletcher, Jamie I., Haber, Michelle, Henderson, Michelle J., Norris, Murray D.

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ABC transporters as mediators of drug resistance and contributors to cancer cell biology von Fletcher, Jamie I, Williams, Rebekka T, Henderson, Michelle J, Norris, Murray D, Haber, Michelle

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SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability von Marshall, Glenn M, Liu, Pei Y, Gherardi, Samuele, Scarlett, Christopher J, Bedalov, Antonio, Xu, Ning, Iraci, Nuncio, Valli, Emanuele, Ling, Dora, Thomas, Wayne, van Bekkum, Margo, Sekyere, Eric, Jankowski, Kacper, Trahair, Toby, Mackenzie, Karen L, Haber, Michelle, Norris, Murray D, Biankin, Andrew V, Perini, Giovanni, Liu, Tao

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Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas von Khan, Aaminah, Gamble, Laura D., Upton, Dannielle H., Ung, Caitlin, Yu, Denise M. T., Ehteda, Anahid, Pandher, Ruby, Mayoh, Chelsea, Hébert, Steven, Jabado, Nada, Kleinman, Claudia L., Burns, Mark R., Norris, Murray D., Haber, Michelle, Tsoli, Maria, Ziegler, David S.

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Too many targets, not enough patients: rethinking neuroblastoma clinical trials von Fletcher, Jamie I., Ziegler, David S., Trahair, Toby N., Marshall, Glenn M., Haber, Michelle, Norris, Murray D.

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The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35 von Liu, Pei Y., Tee, Andrew E., Milazzo, Giorgio, Hannan, Katherine M., Maag, Jesper, Mondal, Sujanna, Atmadibrata, Bernard, Bartonicek, Nenad, Peng, Hui, Ho, Nicholas, Mayoh, Chelsea, Ciaccio, Roberto, Sun, Yuting, Henderson, Michelle J., Gao, Jixuan, Everaert, Celine, Hulme, Amy J., Wong, Matthew, Lan, Qing, Cheung, Belamy B., Shi, Leming, Wang, Jenny Y., Simon, Thorsten, Fischer, Matthias, Zhang, Xu D., Marshall, Glenn M., Norris, Murray D., Haber, Michelle, Vandesompele, Jo, Li, Jinyan, Mestdagh, Pieter, Hannan, Ross D., Dinger, Marcel E., Perini, Giovanni, Liu, Tao

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A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers von Jung, MoonSun, Russell, Amanda J, Liu, Bing, George, Joshy, Liu, Pei Yan, Liu, Tao, DeFazio, Anna, Bowtell, David D L, Oberthuer, André, London, Wendy B, Fletcher, Jamie I, Haber, Michelle, Norris, Murray D, Henderson, Michelle J

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JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma von Wong, Matthew, Sun, Yuting, Xi, Zhichao, Milazzo, Giorgio, Poulos, Rebecca C., Bartenhagen, Christoph, Bell, Jessica L., Mayoh, Chelsea, Ho, Nicholas, Tee, Andrew E., Chen, Xiaoqiong, Li, Yang, Ciaccio, Roberto, Liu, Pei Y., Jiang, Chen C., Lan, Qing, Jayatilleke, Nisitha, Cheung, Belamy B., Haber, Michelle, Norris, Murray D., Zhang, Xu D., Marshall, Glenn M., Wang, Jenny Y., Hüttelmaier, Stefan, Fischer, Matthias, Wong, Jason W. H., Xu, Hongxi, Perini, Giovanni, Dong, Qihan, George, Rani E., Liu, Tao

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The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expression von Tee, Andrew E, Liu, Bing, Song, Renhua, Li, Jinyan, Pasquier, Eddy, Cheung, Belamy B, Jiang, Cizhong, Marshall, Glenn M, Haber, Michelle, Norris, Murray D, Fletcher, Jamie I, Dinger, Marcel E, Liu, Tao

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Potent antileukemic activity of curaxin CBL0137 against MLL‐rearranged leukemia von Somers, Klaartje, Kosciolek, Angelika, Bongers, Angelika, El‐Ayoubi, Ali, Karsa, Mawar, Mayoh, Chelsea, Wadham, Carol, Middlemiss, Shiloh, Neznanov, Nickolay, Kees, Ursula R., Lock, Richard B., Gudkov, Andrei, Sutton, Rosemary, Gurova, Katerina, Haber, Michelle, Norris, Murray D., Henderson, Michelle J.

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Network Modeling of microRNA-mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN von Ooi, Chi Yan, Carter, Daniel R, Liu, Bing, Mayoh, Chelsea, Beckers, Anneleen, Lalwani, Amit, Nagy, Zsuzsanna, De Brouwer, Sara, Decaesteker, Bieke, Hung, Tzong-Tyng, Norris, Murray D, Haber, Michelle, Liu, Tao, De Preter, Katleen, Speleman, Frank, Cheung, Belamy B, Marshall, Glenn M

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Inflammatory response to retrotransposons drives tumor drug resistance that can be prevented by reverse transcriptase inhibitors von Novototskaya-Vlasova, Ksenia A., Neznanov, Nickolay S., Molodtsov, Ivan, Hall, Brandon M., Commane, Mairead, Gleiberman, Anatoli S., Murray, Jayne, Haber, Michelle, Norris, Murray D., Leonova, Katerina I., Gudkov, Andrei V.

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Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG von Ehteda, Anahid, Simon, Sandy, Franshaw, Laura, Giorgi, Federico M., Liu, Jie, Joshi, Swapna, Rouaen, Jourdin R.C., Pang, Chi Nam Ignatius, Pandher, Ruby, Mayoh, Chelsea, Tang, Yujie, Khan, Aaminah, Ung, Caitlin, Tolhurst, Ornella, Kankean, Anne, Hayden, Elisha, Lehmann, Rebecca, Shen, Sylvie, Gopalakrishnan, Anjana, Trebilcock, Peter, Gurova, Katerina, Gudkov, Andrei V., Norris, Murray D., Haber, Michelle, Vittorio, Orazio, Tsoli, Maria, Ziegler, David S.

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Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition von Khan, Aaminah, Valli, Emanuele, Lam, Hayley, Scott, David A., Murray, Jayne, Hanssen, Kimberley M., Eden, Georgina, Gamble, Laura D., Pandher, Rupinder, Flemming, Claudia L., Allan, Sophie, Osterman, Andrei L., Haber, Michelle, Norris, Murray D., Fletcher, Jamie I., Yu, Denise M. T.

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High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment von Heatley, Susan L, Sadras, Teresa, Kok, Chung H, Nievergall, Eva, Quek, Kelly, Dang, Phuong, McClure, Barbara, Venn, Nicola, Moore, Sarah, Suttle, Jeffrey, Law, Tamara, Ng, Anthea, Muskovic, Walter, Norris, Murray D, Revesz, Tamas, Osborn, Michael, Moore, Andrew S, Suppiah, Ram, Fraser, Chris, Alvaro, Frank, Hughes, Timothy P, Mullighan, Charles G, Marshall, Glenn M, Pozza, Luciano Dalla, Yeung, David T, Sutton, Rosemary, White, Deborah L

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Polyamine Antagonist Therapies Inhibit Neuroblastoma Initiation and Progression von Evageliou, Nicholas F, Haber, Michelle, Vu, Annette, Laetsch, Theodore W, Murray, Jayne, Gamble, Laura D, Cheng, Ngan Ching, Liu, Kangning, Reese, Megan, Corrigan, Kelly A, Ziegler, David S, Webber, Hannah, Hayes, Candice S, Pawel, Bruce, Marshall, Glenn M, Zhao, Huaqing, Gilmour, Susan K, Norris, Murray D, Hogarty, Michael D

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OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis von Korotchkina, Lioubov, Kazyulkin, Denis, Komarov, Pavel G., Polinsky, Alex, Andrianova, Ekaterina L., Joshi, Sangeeta, Gupta, Mahima, Vujcic, Slavoljub, Kononov, Eugene, Toshkov, Ilia, Tian, Yuan, Krasnov, Peter, Chernov, Mikhail V., Veith, Jean, Antoch, Marina P., Middlemiss, Shiloh, Somers, Klaartje, Lock, Richard B., Norris, Murray D., Henderson, Michelle J., Haber, Michelle, Chernova, Olga B., Gudkov, Andrei V.

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Macrophage-Derived IL1β and TNFα Regulate Arginine Metabolism in Neuroblastoma von Fultang, Livingstone, Gamble, Laura D, Gneo, Luciana, Berry, Andrea M, Egan, Sharon A, De Bie, Fenna, Yogev, Orli, Eden, Georgina L, Booth, Sarah, Brownhill, Samantha, Vardon, Ashley, McConville, Carmel M, Cheng, Paul N, Norris, Murray D, Etchevers, Heather C, Murray, Jayne, Ziegler, David S, Chesler, Louis, Schmidt, Ronny, Burchill, Susan A, Haber, Michelle, De Santo, Carmela, Mussai, Francis

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Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy von Kamili, Alvin, Gifford, Andrew J., Li, Nancy, Mayoh, Chelsea, Chow, Shu-Oi, Failes, Timothy W., Eden, Georgina L., Cadiz, Roxanne, Xie, Jinhan, Lukeis, Robyn E., Norris, Murray D., Haber, Michelle, McCowage, Geoffrey B., Arndt, Greg M., Trahair, Toby N., Fletcher, Jamie I.

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