Oral berotralstat for the prophylaxis of hereditary angioedema attacks in patients in Japan: A phase 3 randomized trial von Ohsawa, Isao, Honda, Daisuke, Suzuki, Yusuke, Fukuda, Tomoo, Kohga, Keisuke, Morita, Eishin, Moriwaki, Shinichi, Ishikawa, Osamu, Sasaki, Yoshihiro, Tago, Masaki, Chittick, Greg, Cornpropst, Melanie, Murray, Sharon C., Dobo, Sylvia M., Nagy, Eniko, Van Dyke, Sharon, Reese, Lacy, Best, Jessica M., Iocca, Heather, Collis, Phil, Sheridan, William P., Hide, Michihiro

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Randomized Trial of the Efficacy and Safety of Berotralstat (BCX7353) as an Oral Prophylactic Therapy for Hereditary Angioedema: Results of APeX-2 Through 48 Weeks (Part 2) von Wedner, H. James, Aygören-Pürsün, Emel, Bernstein, Jonathan, Craig, Timothy, Gower, Richard, Jacobs, Joshua S., Johnston, Douglas T., Lumry, William R., Zuraw, Bruce L., Best, Jessica M., Iocca, Heather A., Murray, Sharon C., Desai, Bhavisha, Nagy, Eniko, Sheridan, William P., Kiani-Alikhan, Sorena

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Long‐term safety and effectiveness of berotralstat for hereditary angioedema: The open‐label APeX‐S study von Farkas, Henriette, Stobiecki, Marcin, Peter, Jonny, Kinaciyan, Tamar, Maurer, Marcus, Aygören‐Pürsün, Emel, Kiani‐Alikhan, Sorena, Wu, Adrian, Reshef, Avner, Bygum, Anette, Fain, Olivier, Hagin, David, Huissoon, Aarnoud, Jeseňák, Miloš, Lindsay, Karen, Panovska, Vesna Grivcheva, Steiner, Urs C., Zubrinich, Celia, Best, Jessica M., Cornpropst, Melanie, Dix, Daniel, Dobo, Sylvia M., Iocca, Heather A., Desai, Bhavisha, Murray, Sharon C., Nagy, Eniko, Sheridan, William P.

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Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: A randomized, double-blind, placebo-controlled phase 3 trial von Zuraw, Bruce, Lumry, William R., Johnston, Douglas T., Aygören-Pürsün, Emel, Banerji, Aleena, Bernstein, Jonathan A., Christiansen, Sandra C., Jacobs, Joshua S., Sitz, Karl V., Gower, Richard G., Gagnon, Remi, Wedner, H. James, Kinaciyan, Tamar, Hakl, Roman, Hanzlíková, Jana, Anderson, John T., McNeil, Donald L., Fritz, Stephen B., Yang, William H., Tachdjian, Raffi, Busse, Paula J., Craig, Timothy J., Li, H. Henry, Farkas, Henriette, Best, Jessica M., Clemons, Desiree, Cornpropst, Melanie, Dobo, Sylvia M., Iocca, Heather A., Kargl, Deborah, Nagy, Eniko, Murray, Sharon C., Collis, Phil, Sheridan, William P., Maurer, Marcus, Riedl, Marc A.

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Phase I Study of GSK461364, a Specific and Competitive Polo-like Kinase 1 Inhibitor, in Patients with Advanced Solid Malignancies von OLMOS, David, BARKER, Douglas, SMITH, Deborah A, MURRAY, Sharon C, LAMPKIN, Thomas A, DAR, Mohammed M, WILSON, Richard, DE BONO, Johann S, BLAGDEN, Sarah P, SHARMA, Rohini, BRUNETTO, Andre T, YAP, Timothy A, TAEGTMEYER, Anne B, BARRIUSO, Jorge, MEDANI, Hanine, DEGENHARDT, Yan Y, ALLRED, Alicia J

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Single-Dose Safety and Pharmacokinetics of Brecanavir, a Novel Human Immunodeficiency Virus Protease Inhibitor von FORD, Susan L, SUNILA REDDY, Y, ANDERSON, Maggie T, MURRAY, Sharon C, FERNANDEZ, Pedro, STEIN, Daniel S, JOHNSON, Mark A

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Safety and Pharmacokinetics of Brecanavir, a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor, following Repeat Administration with and without Ritonavir in Healthy Adu... von SUNILA REDDY, Y, FORD, Susan L, ANDERSON, Maggie T, MURRAY, Sharon C, NG-CASHIN, Judith, JOHNSON, Mark A

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A dose-escalation study of recombinant human interleukin-18 in combination with rituximab in patients with non-Hodgkin lymphoma von Robertson, Michael J, Kline, Justin, Struemper, Herbert, Koch, Kevin M, Bauman, John W, Gardner, Olivia S, Murray, Sharon C, Germaschewski, Fiona, Weisenbach, Jill, Jonak, Zdenka, Toso, John F

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Single-Dose Pharmacokinetics and Pharmacodynamics of Sergliflozin Etabonate, a Novel Inhibitor of Glucose Reabsorption, in Healthy Volunteers and Patients With Type 2 Diabetes Mell... von Hussey, Elizabeth K., Clark, Richard V., Amin, Dipti M., Kipnes, Mark S., O'Connor-Semmes, Robin L., O'Driscoll, Eilis C., Leong, Jenny, Murray, Sharon C., Dobbins, Robert L., Layko, Debbi, Nunez, Derek J. R.

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Multiple-Dose Pharmacokinetics and Pharmacodynamics of Sergliflozin Etabonate, a Novel Inhibitor of Glucose Reabsorption, in Healthy Overweight and Obese Subjects: A Randomized Dou... von Hussey, Elizabeth K., Dobbins, Robert L., Stoltz, Randall R., Stockman, Nancy L., O'Connor-Semmes, Robin L., Kapur, Anita, Murray, Sharon C., Layko, Debbi, Nunez, Derek J. R.

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Effect of hepatic or renal impairment on the pharmacokinetics of casopitant, a NK-1 receptor antagonist von Bauman, John W., Antal, Joyce M., Adams, Laurel M., Johnson, Brendan M., Murray, Sharon C., Peng, Bin, Kirby, Lyndon C., Lebowitz, Peter F., Marbury, Thomas C., Swan, Suzanne, Gutierrez, Maria

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Sample Size Calculations for Crossover Thorough QT Studies: Satisfaction of Regulatory Threshold and Assay Sensitivity von Anand, Suraj P., Murray, Sharon C., Koch, Gary G.

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Effect of Casopitant, a Novel NK-1 Receptor Antagonist, on the Pharmacokinetics and Pharmacodynamics of Steady-State Warfarin von Kirby, Lyndon C., Johnson, Brendan M., Adams, Laurel M., Eberwein, Derek J., Zhang, Ke, Murray, Sharon C., Lates, Christian D., Blum, Robert A., Morris, Shannon R.

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Intestinal effects of sulfate in drinking water on normal human subjects von HEIZER, W. D, SANDLER, R. S, SEAL, E. JR, MURRAY, S. C, BUSBY, M. G, SCHLIEBE, B. G, PUSEK, S. N

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Long‐term safety and effectiveness of berotralstat for hereditary angioedema: The open‐label APeX‐S study von Farkas, Henriette, Stobiecki, Marcin, Peter, Jonny, Kinaciyan, Tamar, Maurer, Marcus, Aygören‐Pürsün, Emel, Kiani‐Alikhan, Sorena, Wu, Adrian, Reshef, Avner, Bygum, Anette, Fain, Olivier, Hagin, David, Huissoon, Aarnoud, Jeseňák, Miloš, Lindsay, Karen, Panovska, Vesna Grivcheva, Steiner, Urs C, Zubrinich, Celia, Best, Jessica M, Cornpropst, Melanie, Dix, Daniel, Dobo, Sylvia M, Iocca, Heather A, Desai, Bhavisha, Murray, Sharon C, Nagy, Eniko, Sheridan, William P

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Next Generation Pharmaceutical Impactor (A new Impactor for Pharmaceutical inhaler testing). Part II: Archival calibration von MARPLE, Virgil A, OLSON, Bernard A, SANTHANAKRISHNAN, Kumaragovindham, MITCHELL, Jolyon P, MURRAY, Sharon C, HUDSON-CURTIS, Buffy L

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A Dose-Escalation Study of Recombinant Human Interleukin-18 in Combination with Rituximab in Patients with Non-Hodgkin's Lymphoma von Robertson, Michael J., Kline, Justin, Struemper, Herbert, Koch, Kevin M., Bauman, John W., Gardner, Olivia S., Murray, Sharon C., Germaschewski, Fiona, Weisenbach, Jill, Jonak, Zdenka, Toso, John F.

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Aspirin and nonsteroidal anti-inflammatory agents and risk for colorectal adenomas von Sandler, Robert S., Galanko, Joseph C., Murray, Sharon C., Helm, James F., Woosley, John T.

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Micronutrients and the Risk of Colorectal Adenomas von Tseng, Marilyn, Murray, Sharon C., Kupper, Lawrence L., Sandier, Robert S.

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Abstract C132: Effect of hepatic or renal impairment on the pharmacokinetics of casopitant von Bauman, John W., Antal, Joyce M., Adams, Laurel M., Johnson, Brendan M., Murray, Sharon C., Kirby, Lyndon C., Lebowitz, Peter F., Peng, Bin, Marbury, Thomas C., Swan, Suzanne, Gutierrez, Maria

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