Letter to the editor regarding Heringa et al. (2020) paper entitled “Use of the Kinetically-derived Maximum Dose concept in selection of top doses for toxicity studies hampers prop... von Terry, Claire, Domoradzki, Jeanne Y., Fleming, Carrie R., Gehen, Sean C., Mingoia, Robert T., Murphy, Lynea A., Bartels, Michael J.

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Propiconazole-enhanced hepatic cell proliferation is associated with dysregulation of the cholesterol biosynthesis pathway leading to activation of Erk1/2 through Ras farnesylation von Murphy, Lynea A., Moore, Tanya, Nesnow, Stephen

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The hepatocarcinogenic conazoles: cyproconazole, epoxiconazole, and propiconazole induce a common set of toxicological and transcriptional responses von Hester, Susan, Moore, Tanya, Padgett, William T, Murphy, Lynea, Wood, Charles E, Nesnow, Stephen

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Dose-response analysis of epigenetic, metabolic, and apical endpoints after short-term exposure to experimental hepatotoxicants von Miousse, Isabelle R., Murphy, Lynea A., Lin, Haixia, Schisler, Melissa R., Sun, Jinchun, Chalbot, Marie-Cecile G., Sura, Radhakrishna, Johnson, Kamin, LeBaron, Matthew J., Kavouras, Ilias G., Schnackenberg, Laura K., Beger, Richard D., Rasoulpour, Reza J., Koturbash, Igor

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Phosphorylation of CAP-G is required for its chromosomal DNA localization during mitosis von Murphy, Lynea A., Sarge, Kevin D.

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Bridging Sex-Specific Differences in the CAR-Mediated Hepatocarcinogenesis of Nitrapyrin Using Molecular and Apical Endpoints von Murphy, Lynea, LeBaron, Matthew J, Johnson, Kamin, Rasoulpour, Reza J, Wang, Xiujuan, LaRocca, Jessica

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Integration of novel approaches demonstrates simultaneous metabolic inactivation and CAR-mediated hepatocarcinogenesis of a nitrification inhibitor von LaRocca, Jessica L, Rasoulpour, Reza J, Gollapudi, B Bhaskar, Eisenbrandt, David L, Murphy, Lynea A, LeBaron, Matthew J

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HSF1-TPR Interaction Facilitates Export of Stress-induced HSP70 mRNA von Skaggs, Hollie S., Xing, Hongyan, Wilkerson, Donald C., Murphy, Lynea A., Hong, Yiling, Mayhew, Christopher N., Sarge, Kevin D.

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Regulation and Function of SUMO Modification von Hilgarth, Roland S., Murphy, Lynea A., Skaggs, Hollie S., Wilkerson, Donald C., Xing, Hongyan, Sarge, Kevin D.

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Interaction of HSF1 and HSF2 with the Hspa1b Promoter in Mouse Epididymal Spermatozoa von Wilkerson, Donald C, Murphy, Lynea A, Sarge, Kevin D

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Concurrent evaluation of general, immune, and genetic toxicity endpoints as part of an integrated testing strategy von Schisler, Melissa R., Sura, Radhakrishna, Visconti, Nicolo R., Sosinski, Lindsay K., Murphy, Lynea A., LeBaron, Matthew J., Boverhof, Darrell R.

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PRC1 associates with the hsp70i promoter and interacts with HSF2 during mitosis von Murphy, Lynea A., Wilkerson, Donald C., Hong, Yiling, Sarge, Kevin D.

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Interaction of HSF1 and HSF2 with the Hspa1b Promoter in Mouse Epididymal Spermatozoa1 von Wilkerson, Donald C, Murphy, Lynea A, Sarge, Kevin D

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A rat subchronic study transcriptional point of departure estimates a carcinogenicity study apical point of departure von Bianchi, Enrica, Costa, Eduardo, Yan, Zhongyu (June), Murphy, Lynea, Howell, Jessica, Anderson, Donna, Mukerji, Push, Venkatraman, Anand, Terry, Claire, Johnson, Kamin J.

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Identification of Xenopus heat shock transcription factor–2: conserved role of sumoylation in regulating deoxyribonucleic acid–binding activity of heat shock transcription factor–2... von Hilgarth, Roland S., Murphy, Lynea A., O'Connor, Colleen M., Clark, James A., Park-Sarge, Ok-Kyong, Sarge, Kevin D.

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Abstract 1076: Reversible effect of all- trans -retinoic acid on AML12 hepatocyte proliferation and cell cycle progression von Murphy, Lynea, Moore, Tanya, Nesnow, Stephen

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Challenges and opportunities for overcoming dog use in agrochemical evaluation and registration von Bishop, Patricia

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Integrating toxicokinetics into the human health risk assessment process for agrochemicals: Halauxifen-methyl von Terry, Claire, Murphy, Lynea, McCoy, Alene, Aggarwal, Manoj, McFadden, Lisa, Rasoulpour, Reza, Rick, David, Bartels, Michael, Billington, Richard

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Aryl hydrocarbon receptor mode-of-action and human relevance framework for halauxifen-methyl induced rodent liver effects von Murphy, Lynea, LeBaron, Matthew, Marshall, Valerie, McCoy, Alene, Kan, Lynn, Boverhof, Darrell, Bartels, Michael, Terry, Claire, Billington, Richard, Rasoulpour, Reza

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Predicting the Future: Opportunities and Challenges for the Chemical Industry to Apply 21st-Century Toxicity Testing von Settivari, Raja S, Ball, Nicholas, Murphy, Lynea, Rasoulpour, Reza, Boverhof, Darrell R, Carney, Edward W

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