PHARMACOLOGICAL ACTIVITY OF CB‐103 IN HAEMATOLOGICAL MALIGNANCIES – AN ORAL PAN‐NOTCH INHIBITOR WITH A NOVEL MODE OF ACTION von Weber, D., Lehal, R., Frismantas, V., Bourquin, J., Bauer, M., Murone, M., Radtke, F.

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fission yeast dma1 gene is a component of the spindle assembly checkpoint, required to prevent septum formation and premature exit from mitosis if spindle function is compromised von Murone, M, Simanis, V

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Abstract P4-07-05: A novel, first in class Notch transcriptional inhibitor, CB-103 has activity on luminal breast cancer stem cells in combination with fulvestrant von Majumder, S, Crabtree, J, Hossain, F, Murone, M, Lehal, R, Miele, L

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Wnt/Wingless Signaling Requires BCL9/Legless-Mediated Recruitment of Pygopus to the Nuclear β-Catenin-TCF Complex von Kramps, Thomas, Peter, Oliver, Brunner, Erich, Nellen, Denise, Froesch, Barbara, Chatterjee, Sandipan, Murone, Maximilien, Züllig, Stephanie, Basler, Konrad

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66PPharmacological activity of CB-103: An oral pan-NOTCH inhibitor targeting the NOTCH transcription complex von Weber, D, Lehal, R, Frismantas, V, Bourquin, J-P, Bauer, M, Murone, M, Radtke, F

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Pharmacological activity of CB-103: An oral pan-NOTCH inhibitor with a novel mode of action von Weber, D., Lehal, R., Frismantas, V., Bourquin, J-P., Bauer, M., Murone, M., Radtke, F.

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Pharmacological activity of CB-103: An oral pan-NOTCH inhibitor targeting the NOTCH transcription complex von Weber, D., Lehal, R., Frismantas, V., Bourquin, J.-P., Bauer, M., Murone, M., Radtke, F.

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Hematopoietic Deficiencies in c‐mpl and TPO Knockout Mice von Murone, Maximilien, Carpenter, David A., de Sauvage, Frederic J.

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562P Target engagement and clinical safety of CB-103, a first-in-class small molecule inhibitor of the NOTCH transcription complex von Pedrazzoli, A.B. Azaro, Garcia, J.M. Perez, Cortés, J., Miranda, E. Lopez, Colombo, I., Garralda, E., Hess, D., Nuciforo, P.G., Vivancos, A., Ferrarotto, R., Schoenborn-Kellenberger, O., Jorga, K., Vigolo, M., Beni, L., Lehal, R., Murone, M., Bauer, M., Pisa, P., Vogl, F.D., Stathis, A.

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Activating Smoothened mutations in sporadic basal-cell carcinoma von Jr, Ervin H. Epstein, de Sauvage, Frederic J, Xie, Jingwu, Murone, Maximilien, Luoh, Shiuh-Ming, Ryan, Anne, Gu, Qimin, Zhang, Chaohui, Bonifas, Jeannette M, Lam, Ching-Wan, Hynes, Mary, Goddard, Audrey, Rosenthal, Arnon

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Sonic hedgehog signaling by the Patched–Smoothened receptor complex von Murone, Maximilien, Rosenthal, Arnon, de Sauvage, Frederic J.

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Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli von Stone, D M, Murone, M, Luoh, S, Ye, W, Armanini, M P, Gurney, A, Phillips, H, Brush, J, Goddard, A, de Sauvage, F J, Rosenthal, A

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The seven-transmembrane receptor Smoothened cell-autonomously induces multiple ventral cell types von Hynes, Mary, Rosenthal, Arnon, Ye, Weilan, Wang, Kevin, Stone, Donna, Murone, Maximilien, Sauvage, Frederic de

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Gli regulation by the opposing activities of Fused and Suppressor of Fused von de Sauvage, Frederic J, Murone, Maximilien, Luoh, Shiuh-Ming, Stone, Donna, Li, Wenlu, Gurney, Austin, Armanini, Mark, Grey, Christa, Rosenthal, Arnon

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Hedgehog Signal Transduction: From Flies to Vertebrates von Murone, Maximilien, Rosenthal, Arnon, de Sauvage, Frederic J.

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The S. pombe zfs1 gene is required to prevent septation if mitotic progression is inhibited von Beltraminelli, N, Murone, M, Simanis, V

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Efficacy of Low-Dose Intermittent Subcutaneous Interleukin (IL)–2 in Antiviral Drug–Experienced Human Immunodeficiency Virus–Infected Persons with Detectable Virus Load: A Controll... von Tambussi, Giuseppe, Ghezzi, Silvia, Nozza, Silvia, Vallanti, Giuliana, Magenta, Lorenzo, Guffanti, Monica, Brambilla, Andrea, Vicenzi, Elisa, Carrera, Paola, Racca, Sara, Soldini, Laura, Gianotti, Nicola, Murone, Michelangelo, Veglia, Fabrizio, Poli, Guido, Lazzarin, Adriano

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Urinary hydroxylysine glycosides : solid phase extraction and reversed phase chromatographic measurement von CASARI, E, MURONE, M, GRAZIOLI, V

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Dual role of TNF‐α in NK / LAK cell‐mediated lysis of chronically HIV‐infected U1 cells. Concomitant enhancement of HIV expression and sensitization of cell‐mediated lysis... von Fortis, Claudio, Biswas, Priscilla, Soldini, Laura, Veglia, Fabrizio, Careddu, Anna Maria, Delfanti, Fanny, Mantelli, Barbara, Murone, Michelangelo, Lazzarin, Adriano, Poli, Guido

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Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex von Kramps, T, Peter, O, Brunner, E, Nellen, D, Froesch, B, Chatterjee, S, Murone, M, Züllig, S, Basler, K

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