Dose-dependent improvements in outcome with adenoviral expression of interleukin-10 in a murine model of multisystem organ failure von McAuliffe, P F, Murday, M E, Efron, P A, Scumpia, P O, Ungaro, R, Abouhamze, Amer, Tannahill, C L, Hutchins, B, LaFace, D, Moldawer, L L

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Adenoviral Delivery of Human and Viral IL-10 in Murine Sepsis von Minter, Rebecca M, Ferry, Maria A, Murday, Michelle E, Tannahill, Cynthia L, Bahjat, Frances R, Oberholzer, Caroline, Oberholzer, Andreas, LaFace, Drake, Hutchins, Beth, Wen, Shufen, Shinoda, Jeremy, Copeland, Edward M., III, Moldawer, Lyle L

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NOVEL PHARMACOKINETICS OF vIL-10 IN LUNG TISSUE: 272 von Murday, M. E., Shofnos, J., Minter, R. M., Moldawer, L. L.

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Clinical Presentation and Penetrance of Pheochromocytoma/Paraganglioma Syndromes von Benn, Diana E., Gimenez-Roqueplo, Anne-Paule, Reilly, Jennifer R., Bertherat, Jérôme, Burgess, John, Byth, Karen, Croxson, Michael, Dahia, Patricia L. M., Elston, Marianne, Gimm, Oliver, Henley, David, Herman, Philippe, Murday, Victoria, Niccoli-Sire, Patricia, Pasieka, Janice L., Rohmer, Vincent, Tucker, Kathy, Jeunemaitre, Xavier, Marsh, Deborah J., Plouin, Pierre-François, Robinson, Bruce G.

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Mutation update for the CSB/ERCC6 and CSA/ERCC8 genes involved in Cockayne syndrome von Laugel, V, Dalloz, C, Durand, M, Sauvanaud, F, Kristensen, U, Vincent, M.C, Pasquier, L, Odent, S, Cormier-Daire, V, Gener, B, Tobias, E.S, Tolmie, J.L, Martin-Coignard, D, Drouin-Garraud, V, Heron, D, Journel, H, Raffo, E, Vigneron, J, Lyonnet, S, Murday, V, Gubser-Mercati, D, Funalot, B, Brueton, L, Sanchez del Pozo, J, Muñoz, E, Gennery, A.R, Salih, M, Noruzinia, M, Prescott, K, Ramos, L, Stark, Z, Fieggen, K, Chabrol, B, Sarda, P, Edery, P, Bloch-Zupan, A, Fawcett, H, Pham, D, Egly, J.M, Lehmann, A.R, Sarasin, A, Dollfus, H

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Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2 von Afzal, Ali R., Rajab, Anna, Fenske, Christiane D., Oldridge, Michael, Elanko, Navaratnam, Ternes-Pereira, Eliana, Tüysüz, Beyhan, Murday, Victoria A., Patton, Michael A., Wilkie, Andrew O.M., Jeffery, Steve

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Evidence for 28 genetic disorders discovered by combining healthcare and research data von Kaplanis, Joanna, Samocha, Kaitlin E., Wiel, Laurens, Zhang, Zhancheng, Arvai, Kevin J., Eberhardt, Ruth Y., Gallone, Giuseppe, Lelieveld, Stefan H., Martin, Hilary C., McRae, Jeremy F., Short, Patrick J., Torene, Rebecca I., de Boer, Elke, Danecek, Petr, Gardner, Eugene J., Huang, Ni, Lord, Jenny, Martincorena, Iñigo, Pfundt, Rolph, Reijnders, Margot R. F., Yeung, Alison, Yntema, Helger G., Vissers, Lisenka E. L. M., Juusola, Jane, Wright, Caroline F., Brunner, Han G., Firth, Helen V., FitzPatrick, David R., Barrett, Jeffrey C., Hurles, Matthew E., Gilissen, Christian, Retterer, Kyle

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Cancer Risks for BRCA1 and BRCA2 Mutation Carriers: Results From Prospective Analysis of EMBRACE von MAVADDAT, Nasim, PEOCK, Susan, DAVIDSON, Rosemarie, ECCLES, Diana, COLE, Trevor, COOK, Jackie, BREWER, Carole, TISCHKOWITZ, Marc, DOUGLAS, Fiona, HODGSON, Shirley, WALKER, Lisa, PORTEOUS, Mary E, FROST, Debra, MORRISON, Patrick J, SIDE, Lucy E, KENNEDY, M. John, HOUGHTON, Catherine, DONALDSON, Alan, ROGERS, Mark T, DORKINS, Huw, MIEDZYBRODZKA, Zosia, GREGORY, Helen, EASON, Jacqueline, ELLIS, Steve, BARWELL, Julian, MCCANN, Emma, MURRAY, Alex, ANTONIOU, Antonis C, EASTON, Douglas F, PLATTE, Radka, FINEBERG, Elena, EVANS, D. Gareth, IZATT, Louise, EELES, Rosalind A, ADLARD, Julian

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PTEN Mutation Spectrum and Genotype-Phenotype Correlations in Bannayan-Riley-Ruvalcaba Syndrome Suggest a Single Entity With Cowden Syndrome von Marsh, Debbie J., Kum, Jennifer B., Lunetta, Kathryn L., Bennett, Michael J., Gorlin, Robert J., Ahmed, S. Faisal, Bodurtha, Joann, Crowe, Carol, Curtis, Mary A., Dasouki, Majed, Dunn, Teresa, Feit, Howard, Geraghty, Michael T., Graham, John M., Hodgson, Shirley V., Hunter, Alasdair, Korf, Bruce R., Manchester, David, Miesfeldt, Susan, Murday, Victoria A., Nathanson, Katherine L., Parisi, Melissa, Pober, Barbara, Romano, Corrado, Tolmie, John L., Trembath, Richard, Winter, Robin M., Zackai, Elaine H., Zori, Roberto T., Weng, Liang-Ping, Dahia, Patricia L. M., Eng, Charis

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Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas von Palles, Claire, Cazier, Jean-Baptiste, Howarth, Kimberley M, Domingo, Enric, Jones, Angela M, Broderick, Peter, Kemp, Zoe, Spain, Sarah L, Guarino, Estrella, Salguero, Israel, Sherborne, Amy, Chubb, Daniel, Carvajal-Carmona, Luis G, Ma, Yusanne, Kaur, Kulvinder, Dobbins, Sara, Barclay, Ella, Gorman, Maggie, Martin, Lynn, Kovac, Michal B, Humphray, Sean, Lucassen, Anneke, Holmes, Christopher C, Bentley, David, Donnelly, Peter, Taylor, Jenny, Petridis, Christos, Roylance, Rebecca, Sawyer, Elinor J, Kerr, David J, Clark, Susan, Grimes, Jonathan, Kearsey, Stephen E, Thomas, Huw J W, McVean, Gilean, Houlston, Richard S, Tomlinson, Ian

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Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) von MAVADDAT, Nasim, BARROWDALE, Daniel, MULLIGAN, Anna Marie, COUCH, Fergus J, ENGEL, Christoph, MCGUFFOG, Lesley, HEALER, Sue, SINILNIKOVA, Olga M, SOUTHEY, Melissa C, TERRY, Mary Beth, GOLDGAR, David, O'MALLEY, Frances, ANDRULIS, Irene L, JOHN, Esther M, JANAVICIUS, Ramunas, TIHOMIROVA, Laima, HANSEN, Thomas V. O, NIELSEN, Finn C, OSORIO, Ana, STAVROPOULOU, Alexandra, BENITEZ, Javier, MANOUKIAN, Siranoush, PEISSEL, Bernard, DOMCHEK, Susan M, BARILE, Monica, VOLORIO, Sara, PASIN, Barbara, DOLCETTI, Riccardo, PUTIGNANO, Anna Laura, OTTINI, Laura, RADICE, Paolo, HAMANN, Ute, RASHID, Muhammad U, HOGERVORST, Frans B, ECCLES, Diana, KRIEGE, Mieke, VAN DER LUIJT, Rob B, HEBON, PEOCK, Susan, FROST, Debra, GARETH EVANS, D, BREWER, Carole, WALKER, Lisa, ROGERS, Mark T, SIDE, Lucy E, NEVANLINNA, Heli, HOUGHTON, Catherine, EMBRACE, WEAVER, Joellen, GODWIN, Andrew K, SCHMUTZLER, Rita K, WAPPENSCHMIDT, Barbara, MEINDL, Alfons, KAST, Karin, RAMUS, Susan J, SPURDLE, Amanda, ROBSON, Mark, SHERMAN, Mark

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Mutations in FAM20C Are Associated with Lethal Osteosclerotic Bone Dysplasia (Raine Syndrome), Highlighting a Crucial Molecule in Bone Development von Simpson, M.A., Hsu, R., Keir, L.S., Hao, J., Sivapalan, G., Ernst, L.M., Zackai, E.H., Al-Gazali, L.I., Hulskamp, G., Kingston, H.M., Prescott, T.E., Ion, A., Patton, M.A., Murday, V., George, A., Crosby, A.H.

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Obesity, Aspirin, and Risk of Colorectal Cancer in Carriers of Hereditary Colorectal Cancer: A Prospective Investigation in the CAPP2 Study von Movahedi, Mohammad, Bishop, D Timothy, Macrae, Finlay, Mecklin, Jukka-Pekka, Moeslein, Gabriela, Olschwang, Sylviane, Eccles, Diana, Evans, D Gareth, Maher, Eamonn R, Bertario, Lucio, Bisgaard, Marie-Luise, Dunlop, Malcolm G, Ho, Judy W C, Hodgson, Shirley V, Lindblom, Annika, Lubinski, Jan, Morrison, Patrick J, Murday, Victoria, Ramesar, Raj S, Side, Lucy, Scott, Rodney J, Thomas, Huw J W, Vasen, Hans F, Burn, John, Mathers, John C

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Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial von Mathers, John C, Prof, Movahedi, Mohammad, PhD, Macrae, Finlay, Prof, Mecklin, Jukka-Pekka, MD, Moeslein, Gabriela, MD, Olschwang, Sylviane, MD, Eccles, Diana, Prof, Evans, Gareth, Prof, Maher, Eamonn R, Prof, Bertario, Lucio, MD, Bisgaard, Marie-Luise, MD, Dunlop, Malcolm, Prof, Ho, Judy WC, MD, Hodgson, Shirley, Prof, Lindblom, Annika, MD, Lubinski, Jan, Prof, Morrison, Patrick J, Prof, Murday, Victoria, MD, Ramesar, Raj, Prof, Side, Lucy, MD, Scott, Rodney J, PhD, Thomas, Huw JW, PhD, Vasen, Hans, MD, Gerdes, Anne-Marie, Prof, Barker, Gail, Crawford, Gillian, MSc, Elliott, Faye, MSc, Pylvanainen, Kirsi, CRA, Wijnen, Juul, PhD, Fodde, Riccardo, Prof, Lynch, Henry, Prof, Bishop, D Timothy, PhD, Burn, John, Prof Sir

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Mesh Pouch Pexy in the Management of J-Pouch Prolapse von Changchien, Eric M, Griffin, John A, Murday, Michelle E, Bossart, Peter W

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Localization of the gene for Cowden disease to chromosome 10q22–23 von Nelen, M.R., Padberg, G.W., Peeters, E.A.J., Lin, A.Y., Helm, B. van den, Frants, R.R., Goulon, V., Goldstein, A.M., Reen, M.M.M van, Eastern, D.F., Eeles, R.A., Hodgson, S., Mulvihill, J.J., Murday, V.A., Tucker, M.A., Mariman, E.C.M., Starink, T.M., Ponder, B.A.J., Ropers, H.H., Kremer, H., Longy, M., Eng, C.

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A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures von Sharp, Andrew J, Mefford, Heather C, Li, Kelly, Baker, Carl, Skinner, Cindy, Stevenson, Roger E, Schroer, Richard J, Novara, Francesca, De Gregori, Manuela, Ciccone, Roberto, Broomer, Adam, Casuga, Iris, Wang, Yu, Xiao, Chunlin, Barbacioru, Catalin, Gimelli, Giorgio, Bernardina, Bernardo Dalla, Torniero, Claudia, Giorda, Roberto, Regan, Regina, Murday, Victoria, Mansour, Sahar, Fichera, Marco, Castiglia, Lucia, Failla, Pinella, Ventura, Mario, Jiang, Zhaoshi, Cooper, Gregory M, Knight, Samantha J L, Romano, Corrado, Zuffardi, Orsetta, Chen, Caifu, Schwartz, Charles E, Eichler, Evan E

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Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk von Dunlop, Malcolm G, Dobbins, Sara E, Farrington, Susan Mary, Jones, Angela M, Palles, Claire, Whiffin, Nicola, Tenesa, Albert, Spain, Sarah, Broderick, Peter, Ooi, Li-Yin, Domingo, Enric, Smillie, Claire, Henrion, Marc, Frampton, Matthew, Martin, Lynn, Grimes, Graeme, Gorman, Maggie, Semple, Colin, Ma, Yusanne P, Barclay, Ella, Prendergast, James, Cazier, Jean-Baptiste, Olver, Bianca, Penegar, Steven, Lubbe, Steven, Chander, Ian, Carvajal-Carmona, Luis G, Ballereau, Stephane, Lloyd, Amy, Vijayakrishnan, Jayaram, Zgaga, Lina, Rudan, Igor, Theodoratou, Evropi, Starr, John M, Deary, Ian, Kirac, Iva, Kovacević, Dujo, Aaltonen, Lauri A, Renkonen-Sinisalo, Laura, Mecklin, Jukka-Pekka, Matsuda, Koichi, Nakamura, Yusuke, Okada, Yukinori, Gallinger, Steven, Duggan, David J, Conti, David, Newcomb, Polly, Hopper, John, Jenkins, Mark A, Schumacher, Fredrick, Casey, Graham, Easton, Douglas, Shah, Mitul, Pharoah, Paul, Lindblom, Annika, Liu, Tao, Smith, Christopher G, West, Hannah, Cheadle, Jeremy P, Midgley, Rachel, Kerr, David J, Campbell, Harry, Tomlinson, Ian P, Houlston, Richard S

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Molecular Analysis of Pheochromocytoma after Maternal Transmission of SDHD Mutation Elucidates Mechanism of Parent-of-Origin Effect von Yeap, Phey M, Tobias, Edward S, Mavraki, Eleni, Fletcher, Alexander, Bradshaw, Nicola, Freel, E. Marie, Cooke, Alexander, Murday, Victoria A, Davidson, H. Rosemarie, Perry, Colin G, Lindsay, Robert S

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Analysis of rare disruptive germline mutations in 2135 enriched BRCA-negative breast cancers excludes additional high-impact susceptibility genes von Loveday, C., Garrett, A., Hanks, S., Berg, J., Brady, A.F., Cook, J., Donaldson, A., Douglas, F., Greenhalgh, L., Miedzybrodzka, Z., Morrison, P.J., Paterson, J., Ahmed, M., Bardsley, C., Barton, D., Bartlett, M., Baxter, L., Belk, R., Berg, J., Brant, S., Brewer, C., Brice, G., Brooks, C., Campbell, J., Castle, B., Cole, T., Collins, A., Cruger, D., Cummings, C., Davidson, R., Day, L., Dolling, C., Douglas, F., Drummond, S., Edwards, M., Edwards, E., Edwardson, J., Elmslie, F., Evans, G., Ghali, N., Greenhalgh, L., Henderson, A., Hodgson, S., Houlston, R.S., Hunt, V., Izatt, L., Jacobs, C., Jobson, I., Kennedy, M.J., Kightley, C., Kohut, K., Kumar, A., Levene, S., Logan, P., Magee, A., Mansour, S., McBride, D., McEntagart, M., McKeown, C., McLeod, D., Melville, A., Miedzybrodzka, Z., Murday, V., Myhill, K., Myring, J., Pearson, P., Pichert, G., Platt, K., Porteous, M., Protheroe, L., Pugh, S., Randhawa, K., Riddick, C., Robertson, L., Robinson, A., Rowe, S., Schofield, A., Scott, G., Sharif, S., Shaw, A., Shaw, J., Shea-Simonds, J., Side, L., Simon, K., Slater, S., Smith, K., Soloway, J., Steel, M., Stewart, H., Thomas, M., Turner, H., Wakeling, E., Watt, C., Watts, S., Whyte, C., Eccles, D., Evans, D.G., Hanson, H., Houlston, R.S., Turnbull, C.

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