Protein kinase A-mediated phosphorylation of the NF2 tumor suppressor protein merlin at serine 10 affects the actin cytoskeleton von Laulajainen, M, Muranen, T, Carpén, O, Grönholm, M

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A functional association between merlin and HEI10, a cell cycle regulator von GRÖNHOLM, M, MURANEN, T, TOBY, G. G, UTERMARK, T, HANEMANN, C. O, GOLEMIS, E. A, CARPEN, O

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Multistep Phosphorylation by Oncogenic Kinases Enhances the Degradation of the NF2 Tumor Suppressor Merlin von Laulajainen, Minja, Muranen, Taru, Nyman, Tuula A, Carpén, Olli, Grönholm, Mikaela

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DL1-1: Adaptive Resistance to Targeted Therapies von Brugge, JS, Muranen, T, Zoeller, J, Worster, D, Iwanicki, M, Selfors, L, Mills, G

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Cell cycle-dependent nucleocytoplasmic shuttling of the neurofibromatosis 2 tumour suppressor merlin von MURANEN, Taru, GRÖNHOLM, Mikaela, HERMA RENKEMA, G, CARPEN, Olli

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A search for modifying genetic factors in CHEK2:c.1100delC breast cancer patients von Wendt, Camilla, Muranen, Taru A., Mielikäinen, Lotta, Thutkawkorapin, Jessada, Blomqvist, Carl, Jiao, Xiang, Ehrencrona, Hans, Tham, Emma, Arver, Brita, Melin, Beatrice, Kuchinskaya, Ekaterina, Stenmark Askmalm, Marie, Paulsson-Karlsson, Ylva, Einbeigi, Zakaria, von Wachenfeldt Väppling, Anna, Kalso, Eija, Tasmuth, Tiina, Kallioniemi, Anne, Aittomäki, Kristiina, Nevanlinna, Heli, Borg, Åke, Lindblom, Annika

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Fgf receptor genes and breast cancer susceptibility: results from the breast cancer association consortium von Agarwal, D, Pineda, S, Michailidou, K, Alonso, M R, Dennis, J, Wang, Q, Meyer, K B, Menéndez-Rodríguez, P, Mendiola, M, González-Neira, A, Margolin, S, Orr, N, Jones, M, Matsuo, K, Ito, H, Iwata, H, Kondo, N, Hartman, M, Hui, M, Lim, W Y, T-C Iau, P, Sawyer, E, Tomlinson, I, Kerin, M, Kang, D, Noh, D-Y, Southey, M C, Teo, S H, Tay, W-T, Knight, J A, Tchatchou, S, Schmidt, M K, Rosenberg, E H, van't Veer, L J, Beckmann, M W, Yu, J-C, Hou, M-F, Tseng, C-C, Stram, D O, Muir, K, Stewart-Brown, S, Siriwanarangsan, P, Zheng, W, Deming-Halverson, S, Shrubsole, M J, Long, J, Lu, W, Zhang, B, Radice, P, Peterlongo, P, Manoukian, S, McKay, J, Toland, A E, Yannoukakos, D, Fletcher, O, Silva, I dos Santos, Peto, J, Marme, F, Guénel, P, Truong, T, Sanchez, M, Mulot, C, Brenner, H, Arndt, V, Mannermaa, A, Kosma, V-M, Hartikainen, J M, Lambrechts, D, Yesilyurt, B T, Floris, G, Leunen, K, Rudolph, A, Wang, X, Vachon, C, Purrington, K, Giles, G G, Severi, G, Haiman, C A, Simard, J, Labrèche, F, Winqvist, R, Jukkola-Vuorinen, A, Grip, M, Tollenaar, R A E M, Seynaeve, C, Figueroa, J D, Eriksson, M, Hooning, M J, Collée, J M, Tilanus-Linthorst, M, Lubinski, J, Jaworska-Bieniek, K, Durda, K, Muranen, T A, Hall, P, Chenevix-Trench, G, Easton, D F, Pharoah, P D P, Arias-Perez, J I, Milne, R L

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Germ-line variation at a functional p53 binding site increases susceptibility to breast cancer development von Liu, Jianjun, Desai, Kartiki Vasant, Li, Yuqing, Banu, Shakeela, Lee, Yew Kok, Qu, Dianbo, Heikkinen, Tuomas, Aaltonen, Kirsimari, Muranen, Taru A., Kajiji, Tasneem Shabbir, Bonnard, Carine, Aittomäki, Kristiina, von Smitten, Karl, Blomqvist, Carl, Hopper, John L., Southey, Melissa C., Brauch, Hiltrud, Chenevix-Trench, Georgia, Beesley, Jonathan, Spurdle, Amanda B., Chen, Xiaoqing, Czene, Kamila, Hall, Per, Nevanlinna, Heli, Liu, Edison T.

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Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK21100delC Carriers von Schmidt, MK, Hogervorst, F, van Hien, R, Cornelissen, S, Broeks, A, Adank, MA, Meijers, H, Waisfisz, Q, Hollestelle, A, Schutte, M, van den Ouweland, A, Hooning, M, Andrulis, IL, Anton-Culver, H, Antonenkova, NN, Antoniou, AC, Arndt, V, Bermisheva, M, Bogdanova, NV, Bolla, MK, Brauch, H, Brenner, H, Brüning, T, Burwinkel, B, Chang-Claude, J, Chenevix-Trench, G, Couch, FJ, Cox, A, Cross, SS, Czene, K, Dunning, AM, Fasching, PA, Figueroa, J, Fletcher, O, Flyger, H, Galle, E, García-Closas, M, Giles, GG, Haeberle, L, Hall, P, Hillemanns, P, Hopper, JL, Jakubowska, A, John, EM, Jones, M, Khusnutdinova, E, Knight, JA, Kosma, V-M, Kristensen, V, Lee, A, Lindblom, A, Lubinski, J, Mannermaa, A, Margolin, S, Meindl, A, Milne, RL, Muranen, TA, Newcomb, PA, Offit, K, Park-Simon, T-W, Peto, J, Pharoah, PDP, Robson, M, Rudolph, A, Sawyer, EJ, Schmutzler, RK, Seynaeve, C, Soens, J, Southey, MC, Spurdle, AB, Surowy, H, Swerdlow, A, Tollenaar, RAEM, Tomlinson, I, Trentham-Dietz, A, Vachon, C, Wang, Q, Whittemore, AS, Ziogas, A, van der Kolk, L, Nevanlinna, H, Dörk, T, Bojesen, S, Easton, DF

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Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy von Lei, J, Rudolph, A, Moysich, KB, Rafiq, S, Behrens, S, Goode, EL, Pharoah, PD, Seibold, P, Fasching, PA, Andrulis, IL, Kristensen, VN, Couch, FJ, Hamann, U, Hooning, MJ, Nevanlinna, H, Eilber, U, Bolla, MK, Dennis, J, Wang, Q, Lindblom, A, Mannermaa, A, Lambrechts, D, García-Closas, M, Hall, P, Chenevix-Trench, G, Shah, M, Luben, R, Haeberle, L, Ekici, AB, Beckmann, MW, Knight, JA, Glendon, G, Tchatchou, S, Alnæs, GI, Borresen-Dale, AL, Nord, S, Olson, JE, Hallberg, E, Vachon, C, Torres, D, Ulmer, HU, Rüdiger, T, Jager, A, van Deurzen, CH, Tilanus-Linthorst, MM, Muranen, TA, Aittomäki, K, Blomqvist, C, Margolin, S, Kosma, VM, Hartikainen, JM, Kataja, V, Hatse, S, Wildiers, H, Smeets, A, Figueroa, J, Chanock, SJ, Lissowska, J, Li, J, Humphreys, K, Phillips, KA, kConFab Investigators, Linn, S, Cornelissen, S, van den Broek, SA, Kang, D, Choi, JY, Park, SK, Yoo, KY, Hsiung, CN, Wu, PE, Hou, MF, Shen, CY, Teo, SH, Taib, NA, Yip, CH, Ho, GF, Matsuo, K, Ito, H, Iwata, H, Tajima, K, Dunning, AM, Benitez, J, Czene, K, Sucheston, LE, Maishman, T, Tapper, WJ, Eccles, D, Easton, DF, Schmidt, MK, Chang-Claude, J

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Abstract IA04: Stroma-driven resistance to PI3K/mTOR inhibition von Muranen, Taru

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Cell-cell and cell-matrix interactions von Muranen, Taru

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Ovarian Cancer Dissemination-A Cell Biologist's Perspective von Farsinejad, Sadaf, Cattabiani, Thomas, Muranen, Taru, Iwanicki, Marcin

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Inhibition of PI3K/mTOR Leads to Adaptive Resistance in Matrix-Attached Cancer Cells von Muranen, Taru, Selfors, Laura M., Worster, Devin T., Iwanicki, Marcin P., Song, Loling, Morales, Fabiana C., Gao, Sizhen, Mills, Gordon B., Brugge, Joan S.

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Recurrent moderate‐risk mutations in Finnish breast and ovarian cancer patients von Nurmi, Anna, Muranen, Taru A., Pelttari, Liisa M., Kiiski, Johanna I., Heikkinen, Tuomas, Lehto, Sini, Kallioniemi, Anne, Schleutker, Johanna, Bützow, Ralf, Blomqvist, Carl, Aittomäki, Kristiina, Nevanlinna, Heli

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Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications von Muranen, Taru A, Greco, Dario, Fagerholm, Rainer, Kilpivaara, Outi, Kämpjärvi, Kati, Aittomäki, Kristiina, Blomqvist, Carl, Heikkilä, Päivi, Borg, Ake, Nevanlinna, Heli

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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis von Locasale, Jason W, Cantley, Lewis C, Vander Heiden, Matthew G, Grassian, Alexandra R, Melman, Tamar, Lyssiotis, Costas A, Mattaini, Katherine R, Bass, Adam J, Heffron, Gregory, Metallo, Christian M, Muranen, Taru, Sharfi, Hadar, Sasaki, Atsuo T, Anastasiou, Dimitrios, Mullarky, Edouard, Vokes, Natalie I, Sasaki, Mika, Beroukhim, Rameen, Stephanopoulos, Gregory, Ligon, Azra H, Meyerson, Matthew, Richardson, Andrea L, Chin, Lynda, Wagner, Gerhard, Asara, John M, Brugge, Joan S

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Contacting co-culture of human retinal microvascular endothelial cells alters barrier function of human embryonic stem cell derived retinal pigment epithelial cells von Skottman, H., Muranen, J., Lähdekorpi, H., Pajula, E., Mäkelä, K., Koivusalo, L., Koistinen, A., Uusitalo, H., Kaarniranta, K., Juuti-Uusitalo, K.

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E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium von Horne, Hisani N., Oh, Hannah, Sherman, Mark E., Palakal, Maya, Hewitt, Stephen M., Schmidt, Marjanka K., Milne, Roger L., Hardisson, David, Benitez, Javier, Blomqvist, Carl, Bolla, Manjeet K., Brenner, Hermann, Chang-Claude, Jenny, Cora, Renata, Couch, Fergus J., Cuk, Katarina, Devilee, Peter, Easton, Douglas F., Eccles, Diana M., Eilber, Ursula, Hartikainen, Jaana M., Heikkilä, Päivi, Holleczek, Bernd, Hooning, Maartje J., Jones, Michael, Keeman, Renske, Mannermaa, Arto, Martens, John W. M., Muranen, Taru A., Nevanlinna, Heli, Olson, Janet E., Orr, Nick, Perez, Jose I. A., Pharoah, Paul D. P., Ruddy, Kathryn J., Saum, Kai-Uwe, Schoemaker, Minouk J., Seynaeve, Caroline, Sironen, Reijo, Smit, Vincent T. H. B. M., Swerdlow, Anthony J., Tengström, Maria, Thomas, Abigail S., Timmermans, A. Mieke, Tollenaar, Rob A. E. M., Troester, Melissa A., van Asperen, Christi J., van Deurzen, Carolien H. M., Van Leeuwen, Flora F., Van’t Veer, Laura J., García-Closas, Montserrat, Figueroa, Jonine D.

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Alcohol Consumption and Survival after a Breast Cancer Diagnosis: A Literature-Based Meta-analysis and Collaborative Analysis of Data for 29,239 Cases von ALI, Alaa M. G, SCHMIDT, Marjanka K, FLYGER, Henrik, CHANG-CLAUDE, Jenny, VRIELING, Alina, RUDOLPH, Anja, SEIBOLD, Petra, NEVANLINNA, Heli, MURANEN, Taru A, AALTONEN, Kirsimari, BLOMQVIST, Carl, MATSUO, Keitaro, BOLLA, Manjeet K, ITO, Hidemi, IWATA, Hiroji, HORIO, Akiyo, JOHN, Esther M, SHERMAN, Mark, LISSOWSKA, Jolanta, FIGUEROA, Jonine, GARCIA-CLOSAS, Montserrat, ANTON-CULVER, Hoda, SHAH, Mitul, QIN WANG, HOPPER, John L, TRICHOPOULOU, Antonia, BUENO-DE-MESQUITA, Bas, KROGH, Vittorio, WEIDERPASS, Elisabete, ANDERSSON, Anne, CLAVEL-CHAPELON, Françoise, DOSSUS, Laure, FAGHERAZZI, Guy, PEETERS, Petra H, GAGO-DOMINGUEZ, M, OLSEN, Anja, WISHART, Gordon C, EASTON, Douglas F, BORGQUIST, Signe, OVERVAD, Kim, BARRICADE, Aurelio, GONZALEZ, Carlos A, SANCHEZ, María-José, AMIANO, Pilar, RIBOLI, Elio, CASTELAO, J. Esteban, TIM KEY, PHAROAH, Paul D, CARRACEDO, Angel, GARZON, Victor Muñoz, BOJESEN, Stig E, NORDESTGAARD, Børge G

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