Contacting co-culture of human retinal microvascular endothelial cells alters barrier function of human embryonic stem cell derived retinal pigment epithelial cells von Skottman, H., Muranen, J., Lähdekorpi, H., Pajula, E., Mäkelä, K., Koivusalo, L., Koistinen, A., Uusitalo, H., Kaarniranta, K., Juuti-Uusitalo, K.

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Comparison of media for the enumeration of klebsiella from aquatic samples contaminated with domestic and industrial waste waters von Muranen, P. J. J., Niemi, R. M., Niemelä, S. I., Niinioja, R.

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E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium von Horne, Hisani N., Oh, Hannah, Sherman, Mark E., Palakal, Maya, Hewitt, Stephen M., Schmidt, Marjanka K., Milne, Roger L., Hardisson, David, Benitez, Javier, Blomqvist, Carl, Bolla, Manjeet K., Brenner, Hermann, Chang-Claude, Jenny, Cora, Renata, Couch, Fergus J., Cuk, Katarina, Devilee, Peter, Easton, Douglas F., Eccles, Diana M., Eilber, Ursula, Hartikainen, Jaana M., Heikkilä, Päivi, Holleczek, Bernd, Hooning, Maartje J., Jones, Michael, Keeman, Renske, Mannermaa, Arto, Martens, John W. M., Muranen, Taru A., Nevanlinna, Heli, Olson, Janet E., Orr, Nick, Perez, Jose I. A., Pharoah, Paul D. P., Ruddy, Kathryn J., Saum, Kai-Uwe, Schoemaker, Minouk J., Seynaeve, Caroline, Sironen, Reijo, Smit, Vincent T. H. B. M., Swerdlow, Anthony J., Tengström, Maria, Thomas, Abigail S., Timmermans, A. Mieke, Tollenaar, Rob A. E. M., Troester, Melissa A., van Asperen, Christi J., van Deurzen, Carolien H. M., Van Leeuwen, Flora F., Van’t Veer, Laura J., García-Closas, Montserrat, Figueroa, Jonine D.

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Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53 von Lee, Jonathan D., Menasche, Bridget L., Mavrikaki, Maria, Uyemura, Madison M., Hong, Su Min, Kozlova, Nina, Wei, Jin, Alfajaro, Mia M., Filler, Renata B., Müller, Arne, Saxena, Tanvi, Posey, Ryan R., Cheung, Priscilla, Muranen, Taru, Heng, Yujing J., Paulo, Joao A., Wilen, Craig B., Slack, Frank J.

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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis von Locasale, Jason W, Cantley, Lewis C, Vander Heiden, Matthew G, Grassian, Alexandra R, Melman, Tamar, Lyssiotis, Costas A, Mattaini, Katherine R, Bass, Adam J, Heffron, Gregory, Metallo, Christian M, Muranen, Taru, Sharfi, Hadar, Sasaki, Atsuo T, Anastasiou, Dimitrios, Mullarky, Edouard, Vokes, Natalie I, Sasaki, Mika, Beroukhim, Rameen, Stephanopoulos, Gregory, Ligon, Azra H, Meyerson, Matthew, Richardson, Andrea L, Chin, Lynda, Wagner, Gerhard, Asara, John M, Brugge, Joan S

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The Spectrum of FANCM Protein Truncating Variants in European Breast Cancer Cases von Figlioli, Gisella, Kvist, Anders, Tham, Emma, Soukupova, Jana, Kleiblova, Petra, Muranen, Taru A, Andrieu, Nadine, Azzollini, Jacopo, Balmaña, Judith, Barroso, Alicia, Benítez, Javier, Bertelsen, Birgitte, Blanco, Ana, Bonanni, Bernardo, Borg, Åke, Brunet, Joan, Calistri, Daniele, Calvello, Mariarosaria, Chvojka, Stepan, Cortesi, Laura, Darder, Esther, Del Valle, Jesús, Diez, Orland, Eon-Marchais, Séverine, Fostira, Florentia, Gensini, Francesca, Houdayer, Claude, Janatova, Marketa, Kiiski, Johanna I, Konstantopoulou, Irene, Kubelka-Sabit, Katerina, Lázaro, Conxi, Lesueur, Fabienne, Manoukian, Siranoush, Marcinkute, Ruta, Mickys, Ugnius, Moncoutier, Virginie, Myszka, Aleksander, Nguyen-Dumont, Tu, Nielsen, Finn Cilius, Norvilas, Rimvydas, Olah, Edith, Osorio, Ana, Papi, Laura, Peissel, Bernard, Peixoto, Ana, Plaseska-Karanfilska, Dijana, Pócza, Timea, Rossing, Maria, Rudaitis, Vilius, Santamariña, Marta, Santos, Catarina, Smichkoska, Snezhana, Southey, Melissa C, Stoppa-Lyonnet, Dominique, Teixeira, Manuel, Törngren, Therese, Toss, Angela, Urioste, Miguel, Vega, Ana, Vlckova, Zdenka, Yannoukakos, Drakoulis, Zampiga, Valentina, Kleibl, Zdenek, Radice, Paolo, Nevanlinna, Heli, Ehrencrona, Hans, Janavicius, Ramunas, Peterlongo, Paolo

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Alcohol Consumption and Survival after a Breast Cancer Diagnosis: A Literature-Based Meta-analysis and Collaborative Analysis of Data for 29,239 Cases von ALI, Alaa M. G, SCHMIDT, Marjanka K, FLYGER, Henrik, CHANG-CLAUDE, Jenny, VRIELING, Alina, RUDOLPH, Anja, SEIBOLD, Petra, NEVANLINNA, Heli, MURANEN, Taru A, AALTONEN, Kirsimari, BLOMQVIST, Carl, MATSUO, Keitaro, BOLLA, Manjeet K, ITO, Hidemi, IWATA, Hiroji, HORIO, Akiyo, JOHN, Esther M, SHERMAN, Mark, LISSOWSKA, Jolanta, FIGUEROA, Jonine, GARCIA-CLOSAS, Montserrat, ANTON-CULVER, Hoda, SHAH, Mitul, QIN WANG, HOPPER, John L, TRICHOPOULOU, Antonia, BUENO-DE-MESQUITA, Bas, KROGH, Vittorio, WEIDERPASS, Elisabete, ANDERSSON, Anne, CLAVEL-CHAPELON, Françoise, DOSSUS, Laure, FAGHERAZZI, Guy, PEETERS, Petra H, GAGO-DOMINGUEZ, M, OLSEN, Anja, WISHART, Gordon C, EASTON, Douglas F, BORGQUIST, Signe, OVERVAD, Kim, BARRICADE, Aurelio, GONZALEZ, Carlos A, SANCHEZ, María-José, AMIANO, Pilar, RIBOLI, Elio, CASTELAO, J. Esteban, TIM KEY, PHAROAH, Paul D, CARRACEDO, Angel, GARZON, Victor Muñoz, BOJESEN, Stig E, NORDESTGAARD, Børge G

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Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium von Muranen, Taru A, Blomqvist, Carl, Dörk, Thilo, Jakubowska, Anna, Heikkilä, Päivi, Fagerholm, Rainer, Greco, Dario, Aittomäki, Kristiina, Bojesen, Stig E, Shah, Mitul, Dunning, Alison M, Rhenius, Valerie, Hall, Per, Czene, Kamila, Brand, Judith S, Darabi, Hatef, Chang-Claude, Jenny, Rudolph, Anja, Nordestgaard, Børge G, Couch, Fergus J, Hart, Steven N, Figueroa, Jonine, García-Closas, Montserrat, Fasching, Peter A, Beckmann, Matthias W, Li, Jingmei, Liu, Jianjun, Andrulis, Irene L, Winqvist, Robert, Pylkäs, Katri, Mannermaa, Arto, Kataja, Vesa, Lindblom, Annika, Margolin, Sara, Lubinski, Jan, Dubrowinskaja, Natalia, Bolla, Manjeet K, Dennis, Joe, Michailidou, Kyriaki, Wang, Qin, Easton, Douglas F, Pharoah, Paul D P, Schmidt, Marjanka K, Nevanlinna, Heli

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Mendelian randomization study of adiposity-related traits and risk of breast, ovarian, prostate, lung and colorectal cancer von Gao, Chi, Patel, Chirag J, Michailidou, Kyriaki, Peters, Ulrike, Gong, Jian, Schildkraut, Joellen, Schumacher, Fredrick R, Zheng, Wei, Boffetta, Paolo, Stucker, Isabelle, Willett, Walter, Gruber, Stephen, Easton, Douglas F, Hunter, David J, Sellers, Thomas A, Haiman, Christopher, Henderson, Brian E, Hung, Rayjean J, Amos, Christopher, Pierce, Brandon L, Lindström, Sara, Kraft, Peter

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776P Multi-omics analysis of chemo-refractory high-grade serous carcinoma patients: Insights from the DECIDER study von Afenteva, D., Muranen, T.A., Rajavuori, A., Jamalzadeh, S., Zhang, K., Ariotta, V., Isoviita, V-M., Lahtinen, A., Lavikka, K.A., Lehtonen, O., Li, Y., Marchi, G., Oikkonen, J., Salloum, S., Huhtinen, K., Hietanen, S., Virtanen, A., Hynninen, J., Hautaniemi, S.

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Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines von Zhao, Wei, Li, Jun, Chen, Mei-Ju M., Luo, Yikai, Ju, Zhenlin, Nesser, Nicole K., Johnson-Camacho, Katie, Boniface, Christopher T., Lawrence, Yancey, Pande, Nupur T., Davies, Michael A., Herlyn, Meenhard, Muranen, Taru, Zervantonakis, Ioannis K., von Euw, Erika, Schultz, Andre, Kumar, Shwetha V., Korkut, Anil, Spellman, Paul T., Akbani, Rehan, Slamon, Dennis J., Gray, Joe W., Brugge, Joan S., Lu, Yiling, Mills, Gordon B., Liang, Han

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54P Integrative omics workflow identifies credible druggable targets in high-grade serous cancer von Muranen, T.A., Hainari, A., Oikkonen, J., Afenteva, D., Senkowski, W., Wennerberg, K., Hynninen, J., Hautaniemi, S.

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Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK21100delC Carriers von Schmidt, Marjanka K, Hogervorst, Frans, van Hien, Richard, Cornelissen, Sten, Broeks, Annegien, Adank, Muriel A, Meijers, Hanne, Waisfisz, Quinten, Hollestelle, Antoinette, Schutte, Mieke, van den Ouweland, Ans, Hooning, Maartje, Andrulis, Irene L, Anton-Culver, Hoda, Antonenkova, Natalia N, Antoniou, Antonis C, Arndt, Volker, Bermisheva, Marina, Bogdanova, Natalia V, Bolla, Manjeet K, Brauch, Hiltrud, Brenner, Hermann, Brüning, Thomas, Burwinkel, Barbara, Chang-Claude, Jenny, Chenevix-Trench, Georgia, Couch, Fergus J, Cox, Angela, Cross, Simon S, Czene, Kamila, Dunning, Alison M, Fasching, Peter A, Figueroa, Jonine, Fletcher, Olivia, Flyger, Henrik, Galle, Eva, García-Closas, Montserrat, Giles, Graham G, Haeberle, Lothar, Hall, Per, Hillemanns, Peter, Hopper, John L, Jakubowska, Anna, John, Esther M, Jones, Michael, Khusnutdinova, Elza, Knight, Julia A, Kosma, Veli-Matti, Kristensen, Vessela, Lee, Andrew, Lindblom, Annika, Lubinski, Jan, Mannermaa, Arto, Margolin, Sara, Meindl, Alfons, Milne, Roger L, Muranen, Taru A, Newcomb, Polly A, Offit, Kenneth, Park-Simon, Tjoung-Won, Peto, Julian, Pharoah, Paul D P, Robson, Mark, Rudolph, Anja, Sawyer, Elinor J, Schmutzler, Rita K, Seynaeve, Caroline, Soens, Julie, Southey, Melissa C, Spurdle, Amanda B, Surowy, Harald, Swerdlow, Anthony, Tollenaar, Rob A E M, Tomlinson, Ian, Trentham-Dietz, Amy, Vachon, Celine, Wang, Qin, Whittemore, Alice S, Ziogas, Argyrios, van der Kolk, Lizet, Nevanlinna, Heli, Dörk, Thilo, Bojesen, Stig, Easton, Douglas F

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582P Longitudinal, multi-sample characterization of HGSC from DECIDER: A Finnish observational study von Oikkonen, J., Virtanen, A., Li, Y., Isoviita, V-M., Zhang, K., Jamalzadeh, S., Marchi, G., Häkkinen, A., Muranen, T.A., Lahtinen, A., Hietanen, S., Huhtinen, K., Hynninen, J., Hautaniemi, S.

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Comparison of media for the enumeration ofklebsiella from aquatic samples contaminated with domestic and industrial waste waters von Muranen, P. J. J., Niemi, R. M., Niemel, S. I., Niinioja, R.

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Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores von Leslie, Goska, Dennis, Joe, Yang, Xin, Adlard, Julian, Agnarsson, Bjarni A, Ahmed, Munaza, Aittomäki, Kristiina, Arnold, Norbert, Azzollini, Jacopo, Balmaña, Judith, Barkardottir, Rosa B, Barwell, Julian, Belotti, Muriel, Berthet, Pascaline, Boonen, Susanne E, Borg, Åke, Brennan, Paul, Brewer, Carole, Bucalo, Agostino, Buys, Saundra S, Campbell, Ian, Cassingham, Hayley, Christensen, Lise Lotte, Claes, Kathleen B M, Coppa, Anna, Damante, Giuseppe, Davidson, Rosemarie, De Leeneer, Kim, de Putter, Robin, Del Valle, Jesús, Ding, Yuan Chun, Domchek, Susan M, Donaldson, Alan, Eason, Jacqueline, Eeles, Ros, Evans, D Gareth, Feliubadaló, Lidia, Gehrig, Andrea, Giraud, Sophie, Godwin, Andrew K, Gregory, Helen, Hahnen, Eric, Hamann, Ute, Hansen, Thomas V O, Hentschel, Julia, Horvath, Judit, Izquierdo, Angel, Jensen, Uffe Birk, John, Esther M, Kruse, Torben A, Lautrup, Charlotte, Lesueur, Fabienne, Manoukian, Siranoush, Meindl, Alfons, Monteiro, Alvaro N, Morrison, Patrick J, Muranen, Taru A, Nathanson, Katherine L, Neuhausen, Susan L, Nevanlinna, Heli, Niederacher, Dieter, Olah, Edith, Olopade, Olufunmilayo I, Palli, Domenico, Parsons, Michael T, Pedersen, Inge Sokilde, Perez-Segura, Pedro, Petersen, Annabeth H, Pinto, Pedro, Pottinger, Caroline, Ramser, Juliane, Rantala, Johanna, Robson, Mark, Rogers, Mark T, Sánchez de Abajo, Ana María, Shah, Payal D, Sharif, Saba, Side, Lucy E, Steele, Linda, Stoppa-Lyonnet, Dominique, Sutter, Christian, Tan, Yen Yen, Teulé, Alex, Thull, Darcy L, Tischkowitz, Marc, Toland, Amanda E, Tommasi, Stefania, Toss, Angela, Trainer, Alison H, van Asperen, Christi J, Venturelli, Marta, Vijai, Joseph, Walker, Lisa, Wang-Gohrke, Shan, Whaite, Anna, Offit, Kenneth, Simard, Jacques, Easton, Douglas F, Chenevix-Trench, Georgia, Ottini, Laura

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CHEK21100delC Heterozygosity in Women With Breast Cancer Associated With Early Death, Breast Cancer–Specific Death, and Increased Risk of a Second Breast Cancer von WEISCHER, Maren, NORDESTGAARD, Børge G, DEVILEE, Peter, FASCHING, Peter A, ANTON-CULVER, Hoda, LAMBRECHTS, Diether, HOONING, Maartje, COX, Angela, GILES, Graham G, BURWINKEL, Barbara, LINDBLOM, Annika, COUCH, Fergus J, PHAROAH, Paul, MANNERMAA, Arto, GRENAKER ALNOES, Grethe, JOHN, Esther M, DÖRK, Thilo, FLYGER, Henrik, DUNNING, Alison M, QIN WANG, MURANEN, Taru A, VAN HIEN, Richard, FIGUEROA, Jonine, BOLLA, Manjeet K, SOUTHEY, Melissa C, CZENE, Kamila, KNIGHT, Julia A, TOLLENAAR, Rob A. E. M, BECKMANN, Matthias W, ZIOGAS, Argyrios, CHRISTIAENS, Marie-Rose, MARGRIET COLLEE, Johanna, REED, Malcolm W. R, SEVERI, Gianluca, NEVANLINNA, Heli, MARME, Frederik, MARGOLIN, Sara, OLSON, Janet E, KOSMA, Veli-Matti, KRISTENSEN, Vessela N, MIRON, Alexander, BOGDANOVA, Natalia, SHAH, Mitul, BLOMQVIST, Carl, BROEKS, Annegien, VAN'T VEER, Laura J, SHERMAN, Mark, PHILLIPS, Kelly-Anne, JINGMEI LI, JIANJUN LIU, GLENDON, Gord, SEYNAEVE, Caroline, EKICI, Arif B, LEUNEN, Karin, KRIEGE, Mieke, CROSS, Simon S, GARCIA-CLOSAS, Montserrat, HOPPER, John L, HALL, Per, ANDRULIS, Irene L

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Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes von Mavaddat, N, Dorling, L, Carvalho, S, Allen, J, Gonzalez-Neira, A, Keeman, R, Bolla, MK, Dennis, J, Wang, Q, Ahearn, TU, Andrulis, IL, Beckmann, MW, Behrens, S, Benitez, J, Bermisheva, M, Blomqvist, C, Bogdanova, NV, Bojesen, SE, Briceno, I, Bruning, T, Camp, NJ, Campbell, A, Castelao, JE, Chang-Claude, J, Chanock, SJ, Chenevix-Trench, G, Christiansen, H, Czene, K, Dork, T, Eriksson, M, Evans, DG, Fasching, PA, Figueroa, JD, Flyger, H, Gabrielson, M, Gago-Dominguez, M, Geisler, J, Giles, GG, Guenel, P, Hadjisavvas, A, Hahnen, E, Hall, P, Hamann, U, Hartikainen, JM, Hartman, M, Hoppe, R, Howell, A, Jakubowska, A, Jung, A, Khusnutdinova, EK, Kristensen, VN, Li, JM, Lim, SH, Lindblom, A, Loizidou, MA, Lophatananon, A, Lubinski, J, Madsen, MJ, Mannermaa, A, Manoochehri, M, Margolin, S, Mavroudis, D, Milne, RL, Taib, NAM, Morra, A, Muir, K, Obi, N, Osorio, A, Park-Simon, TW, Peterlongo, P, Radice, P, Saloustros, E, Sawyer, EJ, Schmutzler, RK, Shah, M, Sim, X, Southey, MC, Thorne, H, Tomlinson, I, Torres, D, Truong, T, Yip, CH, Spurdle, AB, Vreeswijk, MPG, Dunning, AM, Garcia-Closas, M, Pharoah, PDP, Kvist, A, Muranen, TA, Nevanlinna, H, Teo, SH, Devilee, P, Schmidt, MK, Easton, DF

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Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium von Morra, Anna, Jung, Audrey Y, Behrens, Sabine, Keeman, Renske, Ahearn, Thomas U, Anton-Culver, Hoda, Arndt, Volker, Augustinsson, Annelie, Auvinen, Päivi K, Beane Freeman, Laura E, Becher, Heiko, Beckmann, Matthias W, Blomqvist, Carl, Bojesen, Stig E, Bolla, Manjeet K, Brenner, Hermann, Briceno, Ignacio, Brucker, Sara Y, Camp, Nicola J, Campa, Daniele, Canzian, Federico, Castelao, Jose E, Chanock, Stephen J, Choi, Ji-Yeob, Clarke, Christine L, Couch, Fergus J, Cox, Angela, Cross, Simon S, Czene, Kamila, Dörk, Thilo, Dunning, Alison M, Dwek, Miriam, Easton, Douglas F, Eccles, Diana M, Egan, Kathleen M, Evans, D Gareth, Fasching, Peter A, Flyger, Henrik, Gago-Dominguez, Manuela, Gapstur, Susan M, García-Sáenz, José A, Gaudet, Mia M, Giles, Graham G, Grip, Mervi, Guénel, Pascal, Haiman, Christopher A, Håkansson, Niclas, Hall, Per, Hamann, Ute, Han, Sileny N, Hart, Steven N, Hartman, Mikael, Heyworth, Jane S, Hoppe, Reiner, Hopper, John L, Hunter, David J, Ito, Hidemi, Jager, Agnes, Jakimovska, Milena, Jakubowska, Anna, Janni, Wolfgang, Kaaks, Rudolf, Kang, Daehee, Kapoor, Pooja Middha, Kitahara, Cari M, Koutros, Stella, Kraft, Peter, Kristensen, Vessela N, Lacey, James V, Lambrechts, Diether, Le Marchand, Loic, Li, Jingmei, Lindblom, Annika, Lubiński, Jan, Lush, Michael, Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Mariapun, Shivaani, Matsuo, Keitaro, Mavroudis, Dimitrios, Milne, Roger L, Muranen, Taru A, Newman, William G, Noh, Dong-Young, Nordestgaard, Børge G, Obi, Nadia, Olshan, Andrew F, Olsson, Håkan, Park-Simon, Tjoung-Won, Petridis, Christos, Pharoah, Paul D P, Plaseska-Karanfilska, Dijana, Presneau, Nadege, Rashid, Muhammad U, Rennert, Gad, Rennert, Hedy S, Rhenius, Valerie, Romero, Atocha, Saloustros, Emmanouil

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Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses von Khankari, Nikhil K, Shu, Xiao-Ou, Wen, Wanqing, Kraft, Peter, Lindström, Sara, Peters, Ulrike, Schildkraut, Joellen, Schumacher, Fredrick, Bofetta, Paolo, Risch, Angela, Bickeböller, Heike, Amos, Christopher I, Easton, Douglas, Eeles, Rosalind A, Gruber, Stephen B, Haiman, Christopher A, Hunter, David J, Chanock, Stephen J, Pierce, Brandon L, Zheng, Wei

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