The Role of the Helper Lipid on the DNA Transfection Efficiency of Lipopolyplex Formulations von Du, Zixiu, Munye, Mustafa M., Tagalakis, Aristides D., Manunta, Maria D. I., Hart, Stephen L.

Volltext

COLEC10 is mutated in 3MC patients and regulates early craniofacial development von Munye, Mustafa M, Diaz-Font, Anna, Ocaka, Louise, Henriksen, Maiken L, Lees, Melissa, Brady, Angela, Jenkins, Dagan, Morton, Jenny, Hansen, Soren W, Bacchelli, Chiara, Beales, Philip L, Hernandez-Hernandez, Victor

Volltext

Delivery of ENaC siRNA to epithelial cells mediated by a targeted nanocomplex: a therapeutic strategy for cystic fibrosis von Manunta, Maria D. I., Tagalakis, Aristides D., Attwood, Martin, Aldossary, Ahmad M., Barnes, Josephine L., Munye, Mustafa M., Weng, Alexander, McAnulty, Robin J, Hart, Stephen L.

Volltext

PEGylation improves the receptor-mediated transfection efficiency of peptide-targeted, self-assembling, anionic nanocomplexes von Tagalakis, Aristides D., Kenny, Gavin D., Bienemann, Alison S., McCarthy, David, Munye, Mustafa M., Taylor, Hannah, Wyatt, Marcella J., Lythgoe, Mark F., White, Edward A., Hart, Stephen L.

Volltext

X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3 von Olcese, Chiara, Patel, Mitali P., Shoemark, Amelia, Kiviluoto, Santeri, Legendre, Marie, Williams, Hywel J., Vaughan, Cara K., Hayward, Jane, Goldenberg, Alice, Emes, Richard D., Munye, Mustafa M., Dyer, Laura, Cahill, Thomas, Bevillard, Jeremy, Gehrig, Corinne, Guipponi, Michel, Chantot, Sandra, Duquesnoy, Philippe, Thomas, Lucie, Jeanson, Ludovic, Copin, Bruno, Tamalet, Aline, Thauvin-Robinet, Christel, Papon, Jean- François, Garin, Antoine, Pin, Isabelle, Vera, Gabriella, Aurora, Paul, Fassad, Mahmoud R., Jenkins, Lucy, Boustred, Christopher, Cullup, Thomas, Dixon, Mellisa, Onoufriadis, Alexandros, Bush, Andrew, Chung, Eddie M. K., Antonarakis, Stylianos E., Loebinger, Michael R., Wilson, Robert, Armengot, Miguel, Escudier, Estelle, Hogg, Claire, Amselem, Serge, Sun, Zhaoxia, Bartoloni, Lucia, Blouin, Jean-Louis, Mitchison, Hannah M.

Volltext

A method for concentrating lipid peptide DNA and siRNA nanocomplexes that retains their structure and transfection efficiency von Tagalakis, Aristides D, Castellaro, Sara, Zhou, Haiyan, Bienemann, Alison, Munye, Mustafa M, McCarthy, David, White, Edward A, Hart, Stephen L

Volltext

Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung von Tagalakis, Aristides D, Munye, Mustafa M, Ivanova, Rositsa, Chen, Hanpeng, Smith, Claire M, Aldossary, Ahmad M, Rosa, Luca Z, Moulding, Dale, Barnes, Josephine L, Kafetzis, Konstantinos N, Jones, Stuart A, Baines, Deborah L, Moss, Guy W J, O’Callaghan, Christopher, McAnulty, Robin J, Hart, Stephen L

Volltext

Integrin‐Targeted, Short Interfering RNA Nanocomplexes for Neuroblastoma Tumor‐Specific Delivery Achieve MYCN Silencing with Improved Survival von Tagalakis, Aristides D., Jayarajan, Vignesh, Maeshima, Ruhina, Ho, Kin H., Syed, Farhatullah, Wu, Lin‐Ping, Aldossary, Ahmad M., Munye, Mustafa M., Mistry, Talisa, Ogunbiyi, Olumide Kayode, Sala, Arturo, Standing, Joseph F., Moghimi, Seyed M., Stoker, Andrew W., Hart, Stephen L.

Volltext

Multifunctional, self-assembling anionic peptide-lipid nanocomplexes for targeted siRNA delivery von Tagalakis, Aristides D, Lee, Do Hyang D, Bienemann, Alison S, Zhou, Haiyan, Munye, Mustafa M, Saraiva, Luisa, McCarthy, David, Du, Zixiu, Vink, Conrad A, Maeshima, Ruhina, White, Edward A, Gustafsson, Kenth, Hart, Stephen L

Volltext

Role of liposome and peptide in the synergistic enhancement of transfection with a lipopolyplex vector von Munye, Mustafa M., Ravi, Jascindra, Tagalakis, Aristides D., McCarthy, David, Ryadnov, Maxim G., Hart, Stephen L.

Volltext

BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity von Munye, Mustafa M, Shoemark, Amelia, Hirst, Robert A, Delhove, Juliette M, Sharp, Tyson V, McKay, Tristan R, O'Callaghan, Christopher, Baines, Deborah L, Howe, Steven J, Hart, Stephen L

Volltext

Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer von Munye, Mustafa M., Tagalakis, Aristides D., Barnes, Josephine L., Brown, Rachel E., McAnulty, Robin J., Howe, Steven J., Hart, Stephen L.

Volltext

Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm von Onoufriadis, Alexandros, Shoemark, Amelia, Munye, Mustafa M, James, Chela T, Schmidts, Miriam, Patel, Mitali, Rosser, Elisabeth M, Bacchelli, Chiara, Beales, Philip L, Scambler, Peter J, Hart, Stephen L, Danke-Roelse, Jeannette E, Sloper, John J, Hull, Sarah, Hogg, Claire, Emes, Richard D, Pals, Gerard, Moore, Anthony T, Chung, Eddie M K, Mitchison, Hannah M

Volltext

Improved intracellular delivery of peptide- and lipid-nanoplexes by natural glycosides von Weng, Alexander, Manunta, Maria D.I., Thakur, Mayank, Gilabert-Oriol, Roger, Tagalakis, Aristides D., Eddaoudi, Ayad, Munye, Mustafa M., Vink, Conrad A., Wiesner, Burkhard, Eichhorst, Jenny, Melzig, Matthias F., Hart, Stephen L.

Volltext

A Nanosensor Toolbox for Rapid, Label-Free Measurement of Airway Surface Liquid and Epithelial Cell Function von Ivanova, Rositsa, Benton, David C. H, Munye, Mustafa M, Rangseesorranan, Sarinda, Hart, Stephen L, Moss, Guy W. J

Volltext

Development of process analytical technology to monitor the cell secretome during differentiation of pluripotent stem cells von Ricardo, C. Pinto, Evie, I., Henry, M., Sanchez-Nieto, J.M., Jayawardena, M., Soula, A., Daldoul, K., Arya, M., O'Grady, C., Dewhirst, O., Smart, M., Munye, M., Hasan, J.

Volltext

Development of an end-to-end platform for the controlled, closed, scalable and cost-effective manufacture of allogeneic therapies derived from pluripotent stem cells in aggregate-b... von Agabalyan, N., Mata, M.F., Guenat, J., Valero, I.A., Galali, H., Chikunova, E., Jayawardena, M., Smart, M., Hasan, J., Francois, M., Popova, D., Macown, R., Baptista, R.P., Munye, M.

Volltext

Towards gene therapy for primary ciliary dyskinesia von Munye, M, Hirst, RA, O'Callaghan, C, Howe, SJ, Hart, SL

Volltext

X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3 von Olcese, C, Patel, MP, Shoemark, A, Kiviluoto, S, Legendre, M, Williams, HJ, Vaughan, CK, Hayward, J, Goldenberg, A, Emes, RD, Munye, MM, Dyer, L, Cahill, T, Bevillard, J, Gehrig, C, Guipponi, M, Chantot, S, Duquesnoy, P, Thomas, L, Jeanson, L, Copin, B, Tamalet, A, Thauvin-Robinet, C, Papon, J-F, Garin, A, Pin, I, Vera, G, Aurora, P, Fassad, MR, Jenkins, L, Boustred, C, Cullup, T, Dixon, M, Onoufriadis, A, Bush, A, Chung, EMK, Antonarakis, SE, Loebinger, MR, Wilson, R, Armengot, M, Escudier, E, Hogg, C, Amselem, S, Sun, Z, Bartoloni, L, Blouin, J-L, Mitchison, HM

Volltext

Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm von Onoufriadis, A, Shoemark, A, Munye, MM, James, CT, Schmidts, M, Patel, M, Rosser, EM, Bacchelli, C, Beales, PL, Scambler, PJ, Hart, SL, Danke-Roelse, JE, Sloper, JJ, Hull, S, Hogg, C, Emes, RD, Pals, G, Moore, AT, Chung, EMK, Mitchison, HM

Volltext