Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites von Amambua-Ngwa, Alfred, Tetteh, Kevin K A, Manske, Magnus, Gomez-Escobar, Natalia, Stewart, Lindsay B, Deerhake, M Elizabeth, Cheeseman, Ian H, Newbold, Christopher I, Holder, Anthony A, Knuepfer, Ellen, Janha, Omar, Jallow, Muminatou, Campino, Susana, Macinnis, Bronwyn, Kwiatkowski, Dominic P, Conway, David J

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Imputation-based meta-analysis of severe malaria in three African populations von Band, Gavin, Le, Quang Si, Jostins, Luke, Pirinen, Matti, Kivinen, Katja, Jallow, Muminatou, Sisay-Joof, Fatoumatta, Bojang, Kalifa, Pinder, Margaret, Sirugo, Giorgio, Conway, David J, Nyirongo, Vysaul, Kachala, David, Molyneux, Malcolm, Taylor, Terrie, Ndila, Carolyne, Peshu, Norbert, Marsh, Kevin, Williams, Thomas N, Alcock, Daniel, Andrews, Robert, Edkins, Sarah, Gray, Emma, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Schuldt, Kathrin, Clark, Taane G, Small, Kerrin S, Teo, Yik Ying, Kwiatkowski, Dominic P, Rockett, Kirk A, Barrett, Jeffrey C, Spencer, Chris C A

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Discovery and Validation of Biomarkers to Guide Clinical Management of Pneumonia in African Children von Huang, Honglei, Ideh, Readon C., Gitau, Evelyn, Thézénas, Marie L., Jallow, Muminatou, Ebruke, Bernard, Chimah, Osaretin, Oluwalana, Claire, Karanja, Henri, Mackenzie, Grant, Adegbola, Richard A., Kwiatkowski, Dominic, Kessler, Benedikt M., Berkley, James A., Howie, Stephen R. C., Casals-Pascual, Climent

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Clinical features of severe malaria associated with death: a 13-year observational study in the Gambia von Jallow, Muminatou, Casals-Pascual, Climent, Ackerman, Hans, Walther, Brigitte, Walther, Michael, Pinder, Margaret, Sisay-Joof, Fatou, Usen, Stanley, Jallow, Mariatou, Abubakar, Ismaela, Olaosebikan, Rasaq, Jobarteh, Aminata, Conway, David J, Bojang, Kalifa, Kwiatkowski, Dominic

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Proteomic profiling of the plasma of Gambian children with cerebral malaria von Moussa, Ehab M, Huang, Honglei, Thézénas, Marie L, Fischer, Roman, Ramaprasad, Abhinay, Sisay-Joof, Fatou, Jallow, Muminatou, Pain, Arnab, Kwiatkowski, Dominic, Kessler, Benedikt M, Casals-Pascual, Climent

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Allelic heterogeneity of G6PD deficiency in West Africa and severe malaria susceptibility von Clark, Taane G, Fry, Andrew E, Auburn, Sarah, Campino, Susana, Diakite, Mahamadou, Green, Angela, Richardson, Anna, Teo, Yik Y, Small, Kerrin, Wilson, Jonathan, Jallow, Muminatou, Sisay-Joof, Fatou, Pinder, Margaret, Sabeti, Pardis, Kwiatkowski, Dominic P, Rockett, Kirk A

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Precision identification of high-risk phenotypes and progression pathways in severe malaria without requiring longitudinal data von Johnston, Iain G., Hoffmann, Till, Greenbury, Sam F., Cominetti, Ornella, Jallow, Muminatou, Kwiatkowski, Dominic, Barahona, Mauricio, Jones, Nick S., Casals-Pascual, Climent

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Prevention of the recurrence of anaemia in Gambian children following discharge from hospital von Bojang, Kalifa A, Milligan, Paul J M, Conway, David J, Sisay-Joof, Fatou, Jallow, Muminatou, Nwakanma, Davis C, Abubakr, Ismaela, Njie, Fanta, Greenwood, Brian

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A global reference for human genetic variation von Auton, Adam, Brooks, Lisa D, Durbin, Richard M, Garrison, Erik P, Kang, Hyun Min, Korbel, Jan O, Marchini, Jonathan L, McCarthy, Shane, McVean, Gil A, Abecasis, Gonçalo R

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Classical sickle beta-globin haplotypes exhibit a high degree of long-range haplotype similarity in African and Afro-Caribbean populations von Hanchard, Neil, Elzein, Abier, Trafford, Clare, Rockett, Kirk, Pinder, Margaret, Jallow, Muminatou, Harding, Rosalind, Kwiatkowski, Dominic, McKenzie, Colin

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Screening for Recently Selected Alleles by Analysis of Human Haplotype Similarity von Hanchard, Neil A., Rockett, Kirk A., Spencer, Chris, Coop, Graham, Pinder, Margaret, Jallow, Muminatou, Kimber, Martin, McVean, Gil, Mott, Richard, Kwiatkowski, Dominic P.

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Further evidence supporting a role for gs signal transduction in severe malaria pathogenesis von Auburn, Sarah, Fry, Andrew E, Clark, Taane G, Campino, Susana, Diakite, Mahamadou, Green, Angela, Richardson, Anna, Jallow, Muminatou, Sisay-Joof, Fatou, Pinder, Margaret, Molyneux, Malcolm E, Taylor, Terrie E, Haldar, Kasturi, Rockett, Kirk A, Kwiatkowski, Dominic P

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The variant call format and VCFtools von Danecek, Petr, Auton, Adam, Abecasis, Goncalo, Albers, Cornelis A., Banks, Eric, DePristo, Mark A., Handsaker, Robert E., Lunter, Gerton, Marth, Gabor T., Sherry, Stephen T., McVean, Gilean, Durbin, Richard

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The African Genome Variation Project shapes medical genetics in Africa von Gurdasani, Deepti, Carstensen, Tommy, Tekola-Ayele, Fasil, Pagani, Luca, Tachmazidou, Ioanna, Hatzikotoulas, Konstantinos, Karthikeyan, Savita, Iles, Louise, Pollard, Martin O., Choudhury, Ananyo, Ritchie, Graham R. S., Xue, Yali, Asimit, Jennifer, Nsubuga, Rebecca N., Young, Elizabeth H., Pomilla, Cristina, Kivinen, Katja, Rockett, Kirk, Kamali, Anatoli, Doumatey, Ayo P., Asiki, Gershim, Seeley, Janet, Sisay-Joof, Fatoumatta, Jallow, Muminatou, Tollman, Stephen, Mekonnen, Ephrem, Ekong, Rosemary, Oljira, Tamiru, Bradman, Neil, Bojang, Kalifa, Ramsay, Michele, Adeyemo, Adebowale, Bekele, Endashaw, Motala, Ayesha, Norris, Shane A., Pirie, Fraser, Kaleebu, Pontiano, Kwiatkowski, Dominic, Tyler-Smith, Chris, Rotimi, Charles, Zeggini, Eleftheria, Sandhu, Manjinder S.

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TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expression von Campino, Susana, Forton, Julian, Auburn, Sarah, Fry, Andrew, Diakite, Mahamadou, Richardson, Anna, Hull, Jeremy, Jallow, Muminatou, Sisay-Joof, Fatou, Pinder, Margaret, Molyneux, Malcolm E, Taylor, Terrie E, Rockett, Kirk, Clark, Taane G, Kwiatkowski, Dominic P

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Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania von Band, Gavin, Le, Quang Si, Clarke, Geraldine M., Kivinen, Katja, Hubbart, Christina, Jeffreys, Anna E., Rowlands, Kate, Leffler, Ellen M., Jallow, Muminatou, Conway, David J., Sisay-Joof, Fatoumatta, Sirugo, Giorgio, d’Alessandro, Umberto, Toure, Ousmane B., Thera, Mahamadou A., Konate, Salimata, Sissoko, Sibiri, Mangano, Valentina D., Bougouma, Edith C., Sirima, Sodiomon B., Amenga-Etego, Lucas N., Ghansah, Anita K., Hodgson, Abraham V. O., Wilson, Michael D., Enimil, Anthony, Ansong, Daniel, Evans, Jennifer, Ademola, Subulade A., Apinjoh, Tobias O., Ndila, Carolyne M., Manjurano, Alphaxard, Drakeley, Chris, Reyburn, Hugh, Phu, Nguyen Hoan, Quyen, Nguyen Thi Ngoc, Thai, Cao Quang, Hien, Tran Tinh, Teo, Yik Ying, Manning, Laurens, Laman, Moses, Michon, Pascal, Karunajeewa, Harin, Siba, Peter, Allen, Steve, Allen, Angela, Bahlo, Melanie, Davis, Timothy M. E., Simpson, Victoria, Shelton, Jennifer, Spencer, Chris C. A., Busby, George B. J., Kerasidou, Angeliki, Drury, Eleanor, Stalker, Jim, Dilthey, Alexander, Mentzer, Alexander J., McVean, Gil, Bojang, Kalifa A., Doumbo, Ogobara, Modiano, David, Koram, Kwadwo A., Agbenyega, Tsiri, Amodu, Olukemi K., Achidi, Eric, Williams, Thomas N., Marsh, Kevin, Riley, Eleanor M., Molyneux, Malcolm, Taylor, Terrie, Dunstan, Sarah J., Farrar, Jeremy, Mueller, Ivo, Rockett, Kirk A., Kwiatkowski, Dominic P.

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Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial von Dondorp, Arjen M, MD, Fanello, Caterina I, PhD, Hendriksen, Ilse CE, MD, Gomes, Ermelinda, MD, Seni, Amir, MD, Chhaganlal, Kajal D, MD, Bojang, Kalifa, FRCP, Olaosebikan, Rasaq, FWACP, Anunobi, Nkechinyere, FMCpaed, Maitland, Kathryn, Prof, Kivaya, Esther, MSc, Agbenyega, Tsiri, Prof, Nguah, Samuel Blay, FWACPCH, Evans, Jennifer, MRCPCH, Gesase, Samwel, MD, Kahabuka, Catherine, MD, Mtove, George, MD, Nadjm, Behzad, MD, Deen, Jacqueline, MD, Mwanga-Amumpaire, Juliet, MD, Nansumba, Margaret, MD, Karema, Corine, MD, Umulisa, Noella, MD, Uwimana, Aline, MD, Mokuolu, Olugbenga A, FWACP, Adedoyin, Olanrewaju T, FWACP, Johnson, Wahab BR, Prof, Tshefu, Antoinette K, Prof, Onyamboko, Marie A, MB, Sakulthaew, Tharisara, BNS, Ngum, Wirichada Pan, PhD, Silamut, Kamolrat, PhD, Stepniewska, Kasia, PhD, Woodrow, Charles J, MRCP, Bethell, Delia, MRCPCH, Wills, Bridget, FRCPCH, Oneko, Martina, MD, Peto, Tim E, Prof, von Seidlein, Lorenz, PhD, Day, Nicholas PJ, Prof, White, Nicholas J, Prof

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Nucleotide and haplotypic diversity of the NOS2A promoter region and its relationship to cerebral malaria von BURGNER, David, USEN, Stanley, ROCKETT, Kirk, JALLOW, Muminatou, ACKERMAN, Hans, CERVINO, Alessandra, PINDER, Margaret, KWIATKOWSKI, Dominic P

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Resistance to malaria through structural variation of red blood cell invasion receptors von Leffler, Ellen M., Band, Gavin, Busby, George B. J., Kivinen, Katja, Le, Quang Si, Clarke, Geraldine M., Bojang, Kalifa A., Conway, David J., Jallow, Muminatou, Sisay-Joof, Fatoumatta, Bougouma, Edith C., Mangano, Valentina D., Modiano, David, Sirima, Sodiomon B., Achidi, Eric, Apinjoh, Tobias O., Marsh, Kevin, Ndila, Carolyne M., Peshu, Norbert, Williams, Thomas N., Drakeley, Chris, Manjurano, Alphaxard, Reyburn, Hugh, Riley, Eleanor, Kachala, David, Molyneux, Malcolm, Nyirongo, Vysaul, Taylor, Terrie, Thornton, Nicole, Tilley, Louise, Grimsley, Shane, Drury, Eleanor, Stalker, Jim, Cornelius, Victoria, Hubbart, Christina, Jeffreys, Anna E., Rowlands, Kate, Rockett, Kirk A., Spencer, Chris C. A., Kwiatkowski, Dominic P.

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Malaria protection due to sickle haemoglobin depends on parasite genotype von Band, Gavin, Leffler, Ellen M., Jallow, Muminatou, Sisay-Joof, Fatoumatta, Ndila, Carolyne M., Macharia, Alexander W., Hubbart, Christina, Jeffreys, Anna E., Rowlands, Kate, Nguyen, Thuy, Gonçalves, Sónia, Ariani, Cristina V., Stalker, Jim, Pearson, Richard D., Amato, Roberto, Drury, Eleanor, Sirugo, Giorgio, d’Alessandro, Umberto, Bojang, Kalifa A., Marsh, Kevin, Peshu, Norbert, Saelens, Joseph W., Diakité, Mahamadou, Taylor, Steve M., Conway, David J., Williams, Thomas N., Rockett, Kirk A., Kwiatkowski, Dominic P.

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