PhysiCell: An open source physics-based cell simulator for 3-D multicellular systems von Ghaffarizadeh, Ahmadreza, Heiland, Randy, Friedman, Samuel H, Mumenthaler, Shannon M, Macklin, Paul

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MALDI Mass Spectrometry Imaging for Evaluation of Therapeutics in Colorectal Tumor Organoids von Liu, Xin, Flinders, Colin, Mumenthaler, Shannon M., Hummon, Amanda B.

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3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration von Wang, Hongbing, Brown, Paul C., Chow, Edwin C.Y., Ewart, Lorna, Ferguson, Stephen S., Fitzpatrick, Suzanne, Freedman, Benjamin S., Guo, Grace L., Hedrich, William, Heyward, Scott, Hickman, James, Isoherranen, Nina, Li, Albert P., Liu, Qi, Mumenthaler, Shannon M., Polli, James, Proctor, William R., Ribeiro, Alexandre, Wang, Jian‐Ying, Wange, Ronald L., Huang, Shiew‐Mei

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Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer von Ghate, Nikhil B., Kim, Sungmin, Shin, Yonghwan, Kim, Jinman, Doche, Michael, Valena, Scott, Situ, Alan, Kim, Sangnam, Rhie, Suhn K., Lenz, Heinz-Josef, Ulmer, Tobias S., Mumenthaler, Shannon M., An, Woojin

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Impact of tumor-parenchyma biomechanics on liver metastatic progression: a multi-model approach von Wang, Yafei, Brodin, Erik, Nishii, Kenichiro, Frieboes, Hermann B., Mumenthaler, Shannon M., Sparks, Jessica L., Macklin, Paul

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A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice von Quach, Christine, Song, Ying, Guo, Hongrui, Li, Shun, Maazi, Hadi, Fung, Marshall, Sands, Nathaniel, O’Connell, Douglas, Restrepo-Vassalli, Sara, Chai, Billy, Nemecio, Dali, Punj, Vasu, Akbari, Omid, Idos, Gregory E., Mumenthaler, Shannon M., Wu, Nancy, Martin, Sue Ellen, Hagiya, Ashley, Hicks, James, Cui, Hengmin, Liang, Chengyu

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A high-content image-based method for quantitatively studying context-dependent cell population dynamics von Garvey, Colleen M., Spiller, Erin, Lindsay, Danika, Chiang, Chun-Te, Choi, Nathan C., Agus, David B., Mallick, Parag, Foo, Jasmine, Mumenthaler, Shannon M.

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VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer von Ghate, Nikhil Baban, Kim, Sangnam, Spiller, Erin, Kim, Sungmin, Shin, Yonghwan, Rhie, Suhn K., Smbatyan, Goar, Lenz, Heinz‐Josef, Mumenthaler, Shannon M., An, Woojin

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Leveraging Hypoxia-Activated Prodrugs to Prevent Drug Resistance in Solid Tumors von Lindsay, Danika, Garvey, Colleen M, Mumenthaler, Shannon M, Foo, Jasmine

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Human colorectal cancer-on-chip model to study the microenvironmental influence on early metastatic spread von Strelez, Carly, Chilakala, Sujatha, Ghaffarian, Kimya, Lau, Roy, Spiller, Erin, Ung, Nolan, Hixon, Danielle, Yoon, Ah Young, Sun, Ren X., Lenz, Heinz-Josef, Katz, Jonathan E., Mumenthaler, Shannon M.

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Imaging-Based Machine Learning Analysis of Patient-Derived Tumor Organoid Drug Response von Spiller, Erin R., Ung, Nolan, Kim, Seungil, Patsch, Katherin, Lau, Roy, Strelez, Carly, Doshi, Chirag, Choung, Sarah, Choi, Brandon, Juarez Rosales, Edwin Francisco, Lenz, Heinz-Josef, Matasci, Naim, Mumenthaler, Shannon M.

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Multiplexed imaging and effluent analysis to monitor cancer cell intravasation using a colorectal cancer-on-chip von Strelez, Carly, Ghaffarian, Kimya, Mumenthaler, Shannon M.

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Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes von Mumenthaler, Shannon M, Ng, Patricia Y B, Hodge, Amanda, Bearss, David, Berk, Gregory, Kanekal, Sarath, Redkar, Sanjeev, Taverna, Pietro, Agus, David B, Jain, Anjali

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Targeting stress induction of GRP78 by cardiac glycoside oleandrin dually suppresses cancer and COVID-19 von Ha, Dat P, Shin, Woo-Jin, Liu, Ze, Doche, Michael E, Lau, Roy, Leli, Nektaria Maria, Conn, Crystal S, Russo, Mariangela, Lorenzato, Annalisa, Koumenis, Constantinos, Yu, Min, Mumenthaler, Shannon M, Lee, Amy S

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A novel thin plate spline methodology to model tissue surfaces and quantify tumor cell invasion in organ-on-chip models von Elton, Elizabeth, Strelez, Carly, Ung, Nolan, Perez, Rachel, Ghaffarian, Kimya, Hixon, Danielle, Matasci, Naim, Mumenthaler, Shannon M.

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Predictive Modeling of Drug Response in Non-Hodgkin's Lymphoma von Frieboes, Hermann B, Smith, Bryan R, Wang, Zhihui, Kotsuma, Masakatsu, Ito, Ken, Day, Armin, Cahill, Benjamin, Flinders, Colin, Mumenthaler, Shannon M, Mallick, Parag, Simbawa, Eman, Al-Fhaid, A S, Mahmoud, S R, Gambhir, Sanjiv S, Cristini, Vittorio

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Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer von Arai, Hiroyuki, Xiao, Yi, Loupakis, Fotios, Kawanishi, Natsuko, Wang, Jingyuan, Battaglin, Francesca, Soni, Shivani, Zhang, Wu, Mancao, Christoph, Salhia, Bodour, Mumenthaler, Shannon M, Weisenberger, Daniel J, Liang, Gangning, Cremolini, Chiara, Falcone, Alfredo, Millstein, Joshua, Lenz, Heinz-Josef

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Organs-on-chips: a decade of innovation von Strelez, Carly, Jiang, Hannah Y., Mumenthaler, Shannon M.

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The Impact of Microenvironmental Heterogeneity on the Evolution of Drug Resistance in Cancer Cells von Mumenthaler, Shannon M., Foo, Jasmine, Choi, Nathan C., Heise, Nicholas, Leder, Kevin, Agus, David B., Pao, William, Michor, Franziska, Mallick, Parag

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CCR5 and CCL5 gene expression in colorectal cancer: comprehensive profiling and clinical value von Battaglin, Francesca, Baca, Yasmine, Millstein, Joshua, Yang, Yan, Xiu, Joanne, Arai, Hiroyuki, Wang, Jingyuan, Ou, Fang-Shu, Innocenti, Federico, Mumenthaler, Shannon M, Jayachandran, Priya, Kawanishi, Natsuko, Lenz, Annika, Soni, Shivani, Algaze, Sandra, Zhang, Wu, Khoukaz, Taline, Roussos Torres, Evanthia, Seeber, Andreas, Abraham, Jim P, Lou, Emil, Philip, Philip A, Weinberg, Benjamin A, Shields, Anthony F, Goldberg, Richard M, Marshall, John L, Venook, Alan P, Korn, W Michael, Lenz, Heinz-Josef

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