Xenograft models for normal and malignant stem cells von Goyama, Susumu, Wunderlich, Mark, Mulloy, James C.

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Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia von Huang, Yue, Su, Rui, Sheng, Yue, Dong, Lei, Dong, Ze, Xu, Hongjiao, Ni, Tengfeng, Zhang, Zijie Scott, Zhang, Tao, Li, Chenying, Han, Li, Zhu, Zhenyun, Lian, Fulin, Wei, Jiangbo, Deng, Qiangqiang, Wang, Yungui, Wunderlich, Mark, Gao, Zhiwei, Pan, Guoyu, Zhong, Dafang, Zhou, Hu, Zhang, Naixia, Gan, Jianhua, Jiang, Hualiang, Mulloy, James C., Qian, Zhijian, Chen, Jianjun, Yang, Cai-Guang

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Improved multilineage human hematopoietic reconstitution and function in NSGS mice von Wunderlich, Mark, Chou, Fu-Sheng, Sexton, Christina, Presicce, Pietro, Chougnet, Claire A, Aliberti, Julio, Mulloy, James C

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Targeting IRAK1 as a Therapeutic Approach for Myelodysplastic Syndrome von Rhyasen, Garrett W., Bolanos, Lyndsey, Fang, Jing, Jerez, Andres, Wunderlich, Mark, Rigolino, Carmela, Mathews, Lesley, Ferrer, Marc, Southall, Noel, Guha, Rajarshi, Keller, Jonathan, Thomas, Craig, Beverly, Levi J., Cortelezzi, Agostino, Oliva, Esther N., Cuzzola, Maria, Maciejewski, Jaroslaw P., Mulloy, James C., Starczynowski, Daniel T.

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Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia von Kesarwani, Meenu, Kincaid, Zachary, Gomaa, Ahmed, Huber, Erika, Rohrabaugh, Sara, Siddiqui, Zain, Bouso, Muhammad F, Latif, Tahir, Xu, Ming, Komurov, Kakajan, Mulloy, James C, Cancelas, Jose A, Grimes, H Leighton, Azam, Mohammad

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Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic Leukemia von Lin, Shan, Luo, Roger T., Ptasinska, Anetta, Kerry, Jon, Assi, Salam A., Wunderlich, Mark, Imamura, Toshihiko, Kaberlein, Joseph J., Rayes, Ahmad, Althoff, Mark J., Anastasi, John, O’Brien, Maureen M., Meetei, Amom Ruhikanta, Milne, Thomas A., Bonifer, Constanze, Mulloy, James C., Thirman, Michael J.

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AML cells are differentially sensitive to chemotherapy treatment in a human xenograft model von Wunderlich, Mark, Mizukawa, Benjamin, Chou, Fu-Sheng, Sexton, Christina, Shrestha, Mahesh, Saunthararajah, Yogen, Mulloy, James C.

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Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells von Goyama, Susumu, Schibler, Janet, Cunningham, Lea, Zhang, Yue, Rao, Yalan, Nishimoto, Nahoko, Nakagawa, Masahiro, Olsson, Andre, Wunderlich, Mark, Link, Kevin A, Mizukawa, Benjamin, Grimes, H Leighton, Kurokawa, Mineo, Liu, P Paul, Huang, Gang, Mulloy, James C

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TET1 plays an essential oncogenic role in MLL-rearranged leukemia von Huang, Hao, Jiang, Xi, Li, Zejuan, Li, Yuanyuan, Song, Chun-Xiao, He, Chunjiang, Sun, Miao, Chen, Ping, Gurbuxani, Sandeep, Wang, Jiapeng, Hong, Gia-Ming, Elkahloun, Abdel G., Arnovitz, Stephen, Wang, Jinhua, Szulwach, Keith, Lin, Li, Street, Craig, Wunderlich, Mark, Dawlaty, Meelad, Neilly, Mary Beth, Jaenisch, Rudolf, Yang, Feng-Chun, Mulloy, James C., Jin, Peng, Liu, Paul P., Rowley, Janet D., Xu, Mingjiang, He, Chuan, Chen, Jianjun

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Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia von Ågerstam, Helena, Karlsson, Christine, Hansen, Nils, Sandén, Carl, Askmyr, Maria, von Palffy, Sofia, Högberg, Carl, Rissler, Marianne, Wunderlich, Mark, Juliusson, Gunnar, Richter, Johan, Sjöström, Kjell, Bhatia, Ravi, Mulloy, James C., Järås, Marcus, Fioretos, Thoas

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OKT3 prevents xenogeneic GVHD and allows reliable xenograft initiation from unfractionated human hematopoietic tissues von Wunderlich, Mark, Brooks, Ryan A., Panchal, Rushi, Rhyasen, Garrett W., Danet-Desnoyers, Gwenn, Mulloy, James C.

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Improved chemotherapy modeling with RAG-based immune deficient mice von Wunderlich, Mark, Manning, Nicole, Sexton, Christina, Sabulski, Anthony, Byerly, Luke, O'Brien, Eric, Perentesis, John P, Mizukawa, Benjamin, Mulloy, James C

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Molecular pathogenesis of core binding factor leukemia: current knowledge and future prospects von Goyama, Susumu, Mulloy, James C.

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Comparative utility of NRG and NRGS mice for the study of normal hematopoiesis, leukemogenesis, and therapeutic response von Barve, Aditya, Casson, Lavona, Krem, Maxwell, Wunderlich, Mark, Mulloy, James C., Beverly, Levi J.

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MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199 von Benito, Juliana M., Godfrey, Laura, Kojima, Kensuke, Hogdal, Leah, Wunderlich, Mark, Geng, Huimin, Marzo, Isabel, Harutyunyan, Karine G., Golfman, Leonard, North, Phillip, Kerry, Jon, Ballabio, Erica, Chonghaile, Triona Ní, Gonzalo, Oscar, Qiu, Yihua, Jeremias, Irmela, Debose, LaKiesha, O’Brien, Eric, Ma, Helen, Zhou, Ping, Jacamo, Rodrigo, Park, Eugene, Coombes, Kevin R., Zhang, Nianxiang, Thomas, Deborah A., O’Brien, Susan, Kantarjian, Hagop M., Leverson, Joel D., Kornblau, Steven M., Andreeff, Michael, Müschen, Markus, Zweidler-McKay, Patrick A., Mulloy, James C., Letai, Anthony, Milne, Thomas A., Konopleva, Marina

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Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia von Jiang, Xi, Hu, Chao, Ferchen, Kyle, Nie, Ji, Cui, Xiaolong, Chen, Chih-Hong, Cheng, Liting, Zuo, Zhixiang, Seibel, William, He, Chunjiang, Tang, Yixuan, Skibbe, Jennifer R., Wunderlich, Mark, Reinhold, William C., Dong, Lei, Shen, Chao, Arnovitz, Stephen, Ulrich, Bryan, Lu, Jiuwei, Weng, Hengyou, Su, Rui, Huang, Huilin, Wang, Yungui, Li, Chenying, Qin, Xi, Mulloy, James C., Zheng, Yi, Diao, Jiajie, Jin, Jie, Li, Chong, Liu, Paul P., He, Chuan, Chen, Yuan, Chen, Jianjun

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Functional Niche Competition Between Normal Hematopoietic Stem and Progenitor Cells and Myeloid Leukemia Cells von Glait‐Santar, Chen, Desmond, Ronan, Feng, Xingmin, Bat, Taha, Chen, Jichun, Heuston, Elisabeth, Mizukawa, Benjamin, Mulloy, James C., Bodine, David M., Larochelle, Andre, Dunbar, Cynthia E.

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Rho GTPases in hematopoiesis and hemopathies von Mulloy, James C., Cancelas, Jose A., Filippi, Marie-Dominique, Kalfa, Theodosia A., Guo, Fukun, Zheng, Yi

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CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium von Bertaux‐Skeirik, Nina, Wunderlich, Mark, Teal, Emma, Chakrabarti, Jayati, Biesiada, Jacek, Mahe, Maxime, Sundaram, Nambirajan, Gabre, Joel, Hawkins, Jennifer, Jian, Gao, Engevik, Amy C, Yang, Li, Wang, Jiang, Goldenring, James R, Qualls, Joseph E, Medvedovic, Mario, Helmrath, Michael A, Diwan, Tayyab, Mulloy, James C, Zavros, Yana

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miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia–rearranged leukemia von Chen, Ping, Price, Colles, Li, Zejuan, Li, Yuanyuan, Cao, Donglin, Wiley, Anissa, He, Chunjiang, Gurbuxani, Sandeep, Kunjamma, Rejani B., Huang, Hao, Jiang, Xi, Arnovitz, Stephen, Xu, Mengyi, Hong, Gia-Ming, Elkahloun, Abdel G., Neilly, Mary Beth, Wunderlich, Mark, Larson, Richard A., Le Beau, Michelle M., Mulloy, James C., Liu, Paul P., Rowley, Janet D., Chen, Jianjun

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