Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia von Roberts, Kathryn G, Li, Yongjin, Payne-Turner, Debbie, Harvey, Richard C, Yang, Yung-Li, Pei, Deqing, McCastlain, Kelly, Ding, Li, Lu, Charles, Song, Guangchun, Ma, Jing, Becksfort, Jared, Rusch, Michael, Chen, Shann-Ching, Easton, John, Cheng, Jinjun, Boggs, Kristy, Santiago-Morales, Natalia, Iacobucci, Ilaria, Fulton, Robert S, Wen, Ji, Valentine, Marcus, Cheng, Cheng, Paugh, Steven W, Devidas, Meenakshi, Chen, I-Ming, Reshmi, Shalini, Smith, Amy, Hedlund, Erin, Gupta, Pankaj, Nagahawatte, Panduka, Wu, Gang, Chen, Xiang, Yergeau, Donald, Vadodaria, Bhavin, Mulder, Heather, Winick, Naomi J, Larsen, Eric C, Carroll, William L, Heerema, Nyla A, Carroll, Andrew J, Grayson, Guy, Tasian, Sarah K, Moore, Andrew S, Keller, Frank, Frei-Jones, Melissa, Whitlock, James A, Raetz, Elizabeth A, White, Deborah L, Hughes, Timothy P, Guidry Auvil, Jaime M, Smith, Malcolm A, Marcucci, Guido, Bloomfield, Clara D, Mrózek, Krzysztof, Kohlschmidt, Jessica, Stock, Wendy, Kornblau, Steven M, Konopleva, Marina, Paietta, Elisabeth, Pui, Ching-Hon, Jeha, Sima, Relling, Mary V, Evans, William E, Gerhard, Daniela S, Gastier-Foster, Julie M, Mardis, Elaine, Wilson, Richard K, Loh, Mignon L, Downing, James R, Hunger, Stephen P, Willman, Cheryl L, Zhang, Jinghui, Mullighan, Charles G

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Genome-wide profiling of genetic alterations in acute lymphoblastic leukemia: recent insights and future directions von Mullighan, C G, Downing, J R

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Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia von Gang, E J, Hsieh, Y-T, Pham, J, Zhao, Y, Nguyen, C, Huantes, S, Park, E, Naing, K, Klemm, L, Swaminathan, S, Conway, E M, Pelus, L M, Crispino, J, Mullighan, C G, McMillan, M, Müschen, M, Kahn, M, Kim, Y-M

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PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia von Pang, S H M, Minnich, M, Gangatirkar, P, Zheng, Z, Ebert, A, Song, G, Dickins, R A, Corcoran, L M, Mullighan, C G, Busslinger, M, Huntington, N D, Nutt, S L, Carotta, S

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Genomic profiling of high-risk acute lymphoblastic leukemia von Collins-Underwood, J R, Mullighan, C G

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IDH1 and IDH2 mutations in pediatric acute leukemia von Andersson, A K, Miller, D W, Lynch, J A, Lemoff, A S, Cai, Z, Pounds, S B, Radtke, I, Yan, B, Schuetz, J D, Rubnitz, J E, Ribeiro, R C, Raimondi, S C, Zhang, J, Mullighan, C G, Shurtleff, S A, Schulman, B A, Downing, J R

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Relapse of BCR-ABL1-like ALL mediated by the ABL1 kinase domain mutation T315I following initial response to dasatinib treatment von Yeung, D T, Moulton, D J, Heatley, S L, Nievergall, E, Dang, P, Braley, J, Branford, S, Moore, S, Mullighan, C G, Hughes, T P, White, D L

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Dominant-negative Ikaros cooperates with BCR-ABL1 to induce human acute myeloid leukemia in xenografts von Theocharides, A P A, Dobson, S M, Laurenti, E, Notta, F, Voisin, V, Cheng, P-Y, Yuan, J S, Guidos, C J, Minden, M D, Mullighan, C G, Torlakovic, E, Dick, J E

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Shared acquired genomic changes in zebrafish and human T-ALL von Rudner, L A, Brown, K H, Dobrinski, K P, Bradley, D F, Garcia, M I, Smith, A C H, Downie, J M, Meeker, N D, Look, A T, Downing, J R, Gutierrez, A, Mullighan, C G, Schiffman, J D, Lee, C, Trede, N S, Frazer, J K

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VPREB1 deletions occur independent of lambda light chain rearrangement in childhood acute lymphoblastic leukemia von Mangum, D S, Downie, J, Mason, C C, Jahromi, M S, Joshi, D, Rodic, V, Müschen, M, Meeker, N, Trede, N, Frazer, J K, Zhou, Y, Cheng, C, Jeha, S, Pui, C-H, Willman, C L, Harvey, R C, Hunger, S P, Yang, J J, Barnette, P, Mullighan, C G, Miles, R R, Schiffman, J D

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PS940 COMBINATION BCL‐2 INHIBITOR THERAPY WITH VENETOCLAX AND NAVITOCLAX IN PATIENTS WITH RELAPSED/REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA AND LYMPHOBLASTIC LYMPHOMA von Pullarkat, V.A., Stock, W., Lacayo, N.J., Jabbour, E., Bajel, A., Rubnitz, J., Leonard, J., Mullighan, C.G., Khaw, S.L., Vear, S.I., Salem, A., Schmidt, M., Tong, B., Zhou, Y., Ross, J.A., Bensman, L., Jacobson, A., Alexander, T., Norris, R.

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Highly sensitive MRD tests for ALL based on the IKZF1 Δ3–6 microdeletion von Venn, N C, van der Velden, V H J, de Bie, M, Waanders, E, Giles, J E, Law, T, Kuiper, R P, de Haas, V, Mullighan, C G, Haber, M, Marshall, G M, MD, Norris, van Dongen, J J M, Sutton, R

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KIR Haplotype May Influence Clinical Outcome Following HLA-Matched Sibling Haemopoietic Stem Cell Transplantation von Heatley, S.L, Mullighan, C.G, Sullivan, L.C, Brooks, A.G, Szer, J, Bradstock, K, Schwarer, A.P, Bardy, P.G

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Outcomes of paediatric patients with B-cell acute lymphocytic leukaemia with ABL-class fusion in the pre-tyrosine-kinase inhibitor era: a multicentre, retrospective, cohort study von Boer, M.L. den, Cario, G., Moorman, A.V., Boer, J.M., Groot-Kruseman, H.A. de, Fiocco, M., Escherich, G., Imamura, T., Yeoh, A., Sutton, R., Dalla-Pozza, L., Kiyokawa, N., Schrappe, M., Roberts, K.G., Mullighan, C.G., Hunger, S.P., Vora, A., Attarbaschi, A., Zaliova, M., Elitzur, S., Cazzaniga, G., Biondi, A., Loh, M.L., Pieters, R.

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High-resolution HLA-DQB1 typing using the polymerase chain reaction and sequence-specific primers von Mullighan, C.G., Bunce, M., Welsh, K.I.

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Rapid haplotyping of mutations in the Duffy gene using the polymerase chain reaction and sequence-specific primers von Mullighan, C.G., Marshall, S.E., Fanning, G.C., Briggs, D.C., Welsh, K.I.

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