Uniting GDF15 and GFRAL: Therapeutic Opportunities in Obesity and Beyond von Mullican, Shannon E., Rangwala, Shamina M.

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GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates von Mullican, Shannon E, Lin-Schmidt, Xiefan, Chin, Chen-Ni, Chavez, Jose A, Furman, Jennifer L, Armstrong, Anthony A, Beck, Stephen C, South, Victoria J, Dinh, Thai Q, Cash-Mason, Tanesha D, Cavanaugh, Cassandre R, Nelson, Serena, Huang, Chichi, Hunter, Michael J, Rangwala, Shamina M

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Deacetylase-Independent Function of HDAC3 in Transcription and Metabolism Requires Nuclear Receptor Corepressor von Sun, Zheng, Feng, Dan, Fang, Bin, Mullican, Shannon E., You, Seo-Hee, Lim, Hee-Woong, Everett, Logan J., Nabel, Christopher S., Li, Yun, Selvakumaran, Vignesh, Won, Kyoung-Jae, Lazar, Mitchell A.

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Lipoatrophy and severe metabolic disturbance in mice with fat-specific deletion of PPARγ von Wang, Fenfen, Mullican, Shannon E., DiSpirito, Joanna R., Peed, Lindsey C., Lazar, Mitchell A.

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Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism von Feng, Dan, Liu, Tao, Sun, Zheng, Bugge, Anne, Mullican, Shannon E, Alenghat, Theresa, Liu, X. Shirley, Lazar, Mitchell A

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Rev-erbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function von Bugge, Anne, Feng, Dan, Everett, Logan J, Briggs, Erika R, Mullican, Shannon E, Wang, Fenfen, Jager, Jennifer, Lazar, Mitchell A

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Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation von Mullican, Shannon E, Gaddis, Christine A, Alenghat, Theresa, Nair, Meera G, Giacomin, Paul R, Everett, Logan J, Feng, Dan, Steger, David J, Schug, Jonathan, Artis, David, Lazar, Mitchell A

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HDAC3 is a critical negative regulator of long-term memory formation von McQuown, Susan C, Barrett, Ruth M, Matheos, Dina P, Post, Rebecca J, Rogge, George A, Alenghat, Theresa, Mullican, Shannon E, Jones, Steven, Rusche, James R, Lazar, Mitchell A, Wood, Marcelo A

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Abrogation of nuclear receptors Nr4a3 andNr4a1 leads to development of acute myeloid leukemia von Mullican, Shannon E, Zhang, Shuo, Konopleva, Marina, Ruvolo, Vivian, Andreeff, Michael, Milbrandt, Jeffrey, Conneely, Orla M

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Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology von Lazar, Mitchell A, Alenghat, Theresa, Meyers, Katherine, Mullican, Shannon E, Leitner, Kirstin, Adeniji-Adele, Adetoun, Avila, Jacqueline, Bu an, Maja, Ahima, Rexford S, Kaestner, Klaus H

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Cell-Specific Determinants of Peroxisome Proliferator-Activated Receptor γ Function in Adipocytes and Macrophages von Lefterova, Martina I., Steger, David J., Zhuo, David, Qatanani, Mohammed, Mullican, Shannon E., Tuteja, Geetu, Manduchi, Elisabetta, Grant, Gregory R., Lazar, Mitchell A.

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The orphan nuclear receptors at their 25-year reunion von Mullican, Shannon E, DiSpirito, Joanna R, Lazar, Mitchell A

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Reduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice von Ramirez-Herrick, Ashley M., Mullican, Shannon E., Sheehan, Andrea M., Conneely, Orla M.

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Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis von Alenghat, Theresa, Osborne, Lisa C., Saenz, Steven A., Kobuley, Dmytro, Ziegler, Carly G. K., Mullican, Shannon E., Choi, Inchan, Grunberg, Stephanie, Sinha, Rohini, Wynosky-Dolfi, Meghan, Snyder, Annelise, Giacomin, Paul R., Joyce, Karen L., Hoang, Tram B., Bewtra, Meenakshi, Brodsky, Igor E., Sonnenberg, Gregory F., Bushman, Frederic D., Won, Kyoung-Jae, Lazar, Mitchell A., Artis, David

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Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia von Mullican, Shannon E, Zhang, Shuo, Konopleva, Marina, Ruvolo, Vivian, Andreeff, Michael, Milbrandt, Jeffrey, Conneely, Orla M

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A Novel Adipose-Specific Gene Deletion Model Demonstrates Potential Pitfalls of Existing Methods von Mullican, Shannon E, Tomaru, Takuya, Gaddis, Christine A, Peed, Lindsey C, Sundaram, Anand, Lazar, Mitchell A

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Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions von Hoeksema, Marten A, Gijbels, Marion JJ, Van den Bossche, Jan, van der Velden, Saskia, Sijm, Ayestha, Neele, Annette E, Seijkens, Tom, Stöger, J Lauran, Meiler, Svenja, Boshuizen, Marieke CS, Dallinga‐Thie, Geesje M, Levels, Johannes HM, Boon, Louis, Mullican, Shannon E, Spann, Nathanael J, Cleutjens, Jack P, Glass, Chris K, Lazar, Mitchell A, de Vries, Carlie JM, Biessen, Erik AL, Daemen, Mat JAP, Lutgens, Esther, de Winther, Menno PJ

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Diet-induced Lethality Due to Deletion of the Hdac3 Gene in Heart and Skeletal Muscle von Sun, Zheng, Singh, Nikhil, Mullican, Shannon E., Everett, Logan J., Li, Li, Yuan, Lijun, Liu, Xi, Epstein, Jonathan A., Lazar, Mitchell A.

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Nuclear factor-κB binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome von Yan, Qin, Carmody, Ruaidhri J, Qu, Zhonghua, Ruan, Qingguo, Jager, Jennifer, Mullican, Shannon E, Lazar, Mitchell A, Chen, Youhai H

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Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice von Soccio, Raymond E, Li, Zhenghui, Chen, Eric R, Foong, Yee Hoon, Benson, Kiara K, Dispirito, Joanna R, Mullican, Shannon E, Emmett, Matthew J, Briggs, Erika R, Peed, Lindsey C, Dzeng, Richard K, Medina, Carlos J, Jolivert, Jennifer F, Kissig, Megan, Rajapurkar, Satyajit R, Damle, Manashree, Lim, Hee-Woong, Won, Kyoung-Jae, Seale, Patrick, Steger, David J, Lazar, Mitchell A

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