Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings von Lee, Hyun, Mittal, Anuradha, Patel, Kavankumar, Gatuz, Joseph L., Truong, Lena, Torres, Jaime, Mulhearn, Debbie C., Johnson, Michael E.

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Severe Acute Respiratory Syndrome Coronavirus Papain-like Novel Protease Inhibitors: Design, Synthesis, Protein−Ligand X-ray Structure and Biological Evaluation von Ghosh, Arun K, Takayama, Jun, Rao, Kalapala Venkateswara, Ratia, Kiira, Chaudhuri, Rima, Mulhearn, Debbie C, Lee, Hyun, Nichols, Daniel B, Baliji, Surendranath, Baker, Susan C, Johnson, Michael E, Mesecar, Andrew D

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Structure-Based Design, Synthesis, and Biological Evaluation of a Series of Novel and Reversible Inhibitors for the Severe Acute Respiratory Syndrome−Coronavirus Papain-Like Protea... von Ghosh, Arun K, Takayama, Jun, Aubin, Yoann, Ratia, Kiira, Chaudhuri, Rima, Baez, Yahira, Sleeman, Katrina, Coughlin, Melissa, Nichols, Daniel B, Mulhearn, Debbie C, Prabhakar, Bellur S, Baker, Susan C, Johnson, Michael E, Mesecar, Andrew D

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Role of antibiotic ligand in nascent peptide-dependent ribosome stalling von Vázquez-Laslop, Nora, Klepacki, Dorota, Mulhearn, Debbie C, Ramu, Haripriya, Krasnykh, Olga, Franzblau, Scott, Mankin, Alexander S

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Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors von Ghosh, Arun K., Gong, Gangli, Grum-Tokars, Valerie, Mulhearn, Debbie C., Baker, Susan C., Coughlin, Melissa, Prabhakar, Bellur S., Sleeman, Katrina, Johnson, Michael E., Mesecar, Andrew D.

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Inhibition of MptpB phosphatase from Mycobacterium tuberculosis impairs mycobacterial survival in macrophages von Beresford, Nicola J., Mulhearn, Debbie, Szczepankiewicz, Bruce, Liu, Gang, Johnson, Michael E., Fordham-Skelton, Anthony, Abad-Zapatero, Cele, Cavet, Jennifer S., Tabernero, Lydia

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Structural and Functional Analysis of Two Glutamate Racemase Isozymes from Bacillus anthracis and Implications for Inhibitor Design von May, Melissa, Mehboob, Shahila, Mulhearn, Debbie C., Wang, Zhiqiang, Yu, Huidong, Thatcher, Gregory R.J., Santarsiero, Bernard D., Johnson, Michael E., Mesecar, Andrew D.

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Effect of Ring Strain on the Thiolate−Disulfide Exchange. A Computational Study von Bachrach, Steven M, Woody, Joshua T, Mulhearn, Debbie C

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Design and synthesis of 2-pyridones as novel inhibitors of the Bacillus anthracis enoyl-ACP reductase von Tipparaju, Suresh K., Joyasawal, Sipak, Forrester, Sara, Mulhearn, Debbie C., Pegan, Scott, Johnson, Michael E., Mesecar, Andrew D., Kozikowski, Alan P.

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Design and Synthesis of Aryl Ether Inhibitors of the Bacillus Anthracis Enoyl-ACP Reductase von Tipparaju, Suresh K., Mulhearn, Debbie C., Klein, Gary M., Chen, Yufeng, Tapadar, Subhasish, Bishop, Molly H., Yang, Shuo, Chen, Juan, Ghassemi, Mahmood, Santarsiero, Bernard D., Cook, James L., Johlfs, Mary, Mesecar, Andrew D., Johnson, Michael E., Kozikowski, Alan P.

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Structure of dihydroorotase from Bacillus anthracis at 2.6 Å resolution von Mehboob, Shahila, Mulhearn, Debbie C., Truong, Kent, Johnson, Michael E., Santarsiero, Bernard D.

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Regioselective Covalent Modification of Hemoglobin in Search of Antisickling Agents von Park, Soobong, Hayes, Brittany L, Marankan, Fatima, Mulhearn, Debbie C, Wanna, Linda, Mesecar, Andrew D, Santarsiero, Bernard D, Johnson, Michael E, Venton, Duane L

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Selective Nucleophilic Attack of Trisulfides. An ab Initio Study von Mulhearn, Debbie C, Bachrach, Steven M

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Design, synthesis, and evaluation of oxyanion-hole selective inhibitor substituents for the S1 subsite of factor Xa von Rumthao, Sochanchingwung, Lee, Oukseub, Sheng, Qi, Fu, WenTao, Mulhearn, Debbie C., Crich, David, Mesecar, Andrew D., Johnson, Michael E.

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Structural model of a complex between the heterotrimeric G protein, Gsα, and tubulin von Layden, Brian T., Saengsawang, Witchuda, Donati, Robert J., Yang, Shuo, Mulhearn, Debbie C., Johnson, Michael E., Rasenick, Mark M.

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Hydrogen Shifts in Formyl- and Diformylphosphine von Mulhearn, Debbie C, Bachrach, Steven M

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Nucleophilic Substitution at Sulfur:  SN2 or Addition−Elimination? von Bachrach, Steven M, Mulhearn, Debbie C

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α-Effect in Menschutkin alkylations von Fountain, K. R, Hutchinson, Linda K, Mulhearn, Debbie C, Xu, Yu Bo

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Ab initio investigation of the diels-alder reaction between 2H-phosphole and phosphaethene: A model for phosphole dimerization von Salzner, Ulrike, Bachrach, Steven M., Mulhearn, Debbie C.

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Structure of dihydroorotase from Bacillus anthracis at 2.6Å resolution von Mehboob, Shahila, Mulhearn, Debbie C, Truong, Kent, Johnson, Michael E, Santarsiero, Bernard D

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