Mapping microglia states in the human brain through the integration of high-dimensional techniques von Sankowski, Roman, Böttcher, Chotima, Masuda, Takahiro, Geirsdottir, Laufey, Sagar, Sindram, Elena, Seredenina, Tamara, Muhs, Andreas, Scheiwe, Christian, Shah, Mukesch Johannes, Heiland, Dieter Henrik, Schnell, Oliver, Grün, Dominic, Priller, Josef, Prinz, Marco

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Discovery and preclinical characterization of [18F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer’s disease and other tauopathies von Kroth, Heiko, Oden, Felix, Molette, Jerome, Schieferstein, Hanno, Capotosti, Francesca, Mueller, Andre, Berndt, Mathias, Schmitt-Willich, Heribert, Darmency, Vincent, Gabellieri, Emanuele, Boudou, Cédric, Juergens, Tanja, Varisco, Yvan, Vokali, Efthymia, Hickman, David T., Tamagnan, Gilles, Pfeifer, Andrea, Dinkelborg, Ludger, Muhs, Andreas, Stephens, Andrew

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Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau.P301L mice that model tauopathy von Theunis, Clara, Crespo-Biel, Natalia, Gafner, Valérie, Pihlgren, Maria, López-Deber, María Pilar, Reis, Pedro, Hickman, David T, Adolfsson, Oskar, Chuard, Nathalie, Ndao, Dorin Mlaki, Borghgraef, Peter, Devijver, Herman, Van Leuven, Fred, Pfeifer, Andrea, Muhs, Andreas

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Aβ42 Neurotoxicity Is Mediated by Ongoing Nucleated Polymerization Process Rather than by Discrete Aβ42 Species von Jan, Asad, Adolfsson, Oskar, Allaman, Igor, Buccarello, Anna-Lucia, Magistretti, Pierre J., Pfeifer, Andrea, Muhs, Andreas, Lashuel, Hilal A.

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Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement von Lee, Seung-Hye, Le Pichon, Claire E., Adolfsson, Oskar, Gafner, Valérie, Pihlgren, Maria, Lin, Han, Solanoy, Hilda, Brendza, Robert, Ngu, Hai, Foreman, Oded, Chan, Ruby, Ernst, James A., DiCara, Danielle, Hotzel, Isidro, Srinivasan, Karpagam, Hansen, David V., Atwal, Jasvinder, Lu, Yanmei, Bumbaca, Daniela, Pfeifer, Andrea, Watts, Ryan J., Muhs, Andreas, Scearce-Levie, Kimberly, Ayalon, Gai

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Calpain-mediated tau fragmentation is altered in Alzheimer’s disease progression von Chen, Hsu-Hsin, Liu, Peter, Auger, Paul, Lee, Seung-Hye, Adolfsson, Oskar, Rey-Bellet, Lorianne, Lafrance-Vanasse, Julien, Friedman, Brad A., Pihlgren, Maria, Muhs, Andreas, Pfeifer, Andrea, Ernst, James, Ayalon, Gai, Wildsmith, Kristin R., Beach, Thomas G., van der Brug, Marcel P.

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An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome von Belichenko, Pavel V, Madani, Rime, Rey-Bellet, Lorianne, Pihlgren, Maria, Becker, Ann, Plassard, Adeline, Vuillermot, Stephanie, Giriens, Valérie, Nosheny, Rachel L, Kleschevnikov, Alexander M, Valletta, Janice S, Bengtsson, Sara K S, Linke, Gordon R, Maloney, Michael T, Hickman, David T, Reis, Pedro, Granet, Anne, Mlaki, Dorin, Lopez-Deber, Maria Pilar, Do, Long, Singhal, Nishant, Masliah, Eliezer, Pearn, Matthew L, Pfeifer, Andrea, Muhs, Andreas, Mobley, William C

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Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice von Muhs, Andreas, Hickman, David T, Pihlgren, Maria, Chuard, Nathalie, Giriens, Valérie, Meerschman, Carine, van der Auwera, Ingrid, van Leuven, Fred, Sugawara, Masae, Weingertner, Marie-Catherine, Bechinger, Burkhard, Greferath, Ruth, Kolonko, Nadine, Nagel-Steger, Luitgard, Riesner, Detlev, Brady, Roscoe O, Pfeifer, Andrea, Nicolau, Claude

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Human genome–guided identification of memory-modulating drugs von Papassotiropoulos, Andreas, Gerhards, Christiane, Heck, Angela, Ackermann, Sandra, Aerni, Amanda, Schicktanz, Nathalie, Auschra, Bianca, Demougin, Philippe, Mumme, Eva, Elbert, Thomas, Ertl, Verena, Gschwind, Leo, Hanser, Edveena, Huynh, Kim-Dung, Jessen, Frank, Kolassa, Iris-Tatjana, Milnik, Annette, Paganetti, Paolo, Spalek, Klara, Vogler, Christian, Muhs, Andreas, Pfeifer, Andrea, de Quervain, Dominique J-F

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Engineering amyloid-like assemblies from unstructured peptides via site-specific lipid conjugation von López Deber, María Pilar, Hickman, David T, Nand, Deepak, Baldus, Marc, Pfeifer, Andrea, Muhs, Andreas

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Development of a small D-enantiomeric Alzheimer's amyloid-β binding peptide ligand for future in vivo imaging applications von Funke, Susanne Aileen, Bartnik, Dirk, Glück, Julian Marius, Piorkowska, Kasia, Wiesehan, Katja, Weber, Urs, Gulyas, Balazs, Halldin, Christer, Pfeifer, Andrea, Spenger, Christian, Muhs, Andreas, Willbold, Dieter

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PRECLINICAL CHARACTERIZATION OF PI-2620, A NOVEL TAU PET TRACER FOR DETECTION OF TAU IN AD AND OTHER TAUOPATHIES von Mueller, Andre, Kroth, Heiko, Schieferstein, Hanno, Berndt, Mathias, Oden, Felix, Capotosti, Francesca, Molette, Jerome, Juergens, Tanja, Darmency, Vincent, Schmitt-Willich, Heribert, Hickman, David, Tamagnan, Gilles, Pfeifer, Andrea, Dinkelborg, Ludger, Muhs, Andreas, Stephens, Andrew

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A beta 42 Neurotoxicity Is Mediated by Ongoing Nucleated Polymerization Process Rather than by Discrete A beta 42 Species von Jan, Asad, Adolfsson, Oskar, Allaman, Igor, Buccarello, Anna-Lucia, Magistretti, Pierre J, Pfeifer, Andrea, Muhs, Andreas, Lashuel, Hilal A

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An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ von Adolfsson, Oskar, Pihlgren, Maria, Toni, Nicolas, Varisco, Yvan, Buccarello, Anna Lucia, Antoniello, Katia, Lohmann, Sophie, Piorkowska, Kasia, Gafner, Valerie, Atwal, Jasvinder K, Maloney, Janice, Chen, Mark, Gogineni, Alvin, Weimer, Robby M, Mortensen, Deborah L, Friesenhahn, Michel, Ho, Carole, Paul, Robert, Pfeifer, Andrea, Muhs, Andreas, Watts, Ryan J

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Binding Affinity Measurement of Antibodies from Crude Hybridoma Samples by SPR von Ndao, Dorin, Hickman, David, López-Deber, María, Davranche, Aurélien, Pfeifer, Andrea, Muhs, Andreas

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Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin von Ultsch, Mark, Li, Bing, Maurer, Till, Mathieu, Mary, Adolfsson, Oskar, Muhs, Andreas, Pfeifer, Andrea, Pihlgren, Maria, Bainbridge, Travis W., Reichelt, Mike, Ernst, James A., Eigenbrot, Charles, Fuh, Germaine, Atwal, Jasvinder K., Watts, Ryan J., Wang, Weiru

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A Short Synthesis of the 2‑Bromo‑N,9-dimethyl-6,7,8,9-tetrahydro‑5H‑pyrido[2,3‑b]indol-6-amine Building Block von Sreenivasachary, Nampally, Kroth, Heiko, Benderitter, Pascal, Barth, Wolfgang, Pfeifer, Andrea, Muhs, Andreas

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A Short Synthesis of the 2-Bromo- N ,9-dimethyl-6,7,8,9-tetrahydro-5 H -pyrido[2,3- b ]indol-6-amine Building Block von Sreenivasachary, Nampally, Kroth, Heiko, Benderitter, Pascal, Barth, Wolfgang, Pfeifer, Andrea, Muhs, Andreas

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BACE-1 is expressed in the blood–brain barrier endothelium and is upregulated in a murine model of Alzheimer’s disease von Devraj, Kavi, Poznanovic, Slobodan, Spahn, Christoph, Schwall, Gerhard, Harter, Patrick N, Mittelbronn, Michel, Antoniello, Katia, Paganetti, Paolo, Muhs, Andreas, Heilemann, Mike, Hawkins, Richard A, Schrattenholz, André, Liebner, Stefan

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Author Correction: Mapping microglia states in the human brain through the integration of high-dimensional techniques von Sankowski, Roman, Böttcher, Chotima, Masuda, Takahiro, Geirsdottir, Laufey, Sagar, Sindram, Elena, Seredenina, Tamara, Muhs, Andreas, Scheiwe, Christian, Shah, Mukesch Johannes, Heiland, Dieter Henrik, Schnell, Oliver, Grün, Dominic, Priller, Josef, Prinz, Marco

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