IN VIVO ACTIVATION OF ANTIGEN-SPECIFIC CD4 T CELLS von Jenkins, Marc K, Khoruts, Alexander, Ingulli, Elizabeth, Mueller, Daniel L, McSorley, Stephen J, Reinhardt, R. Lee, Itano, Andrea, Pape, Kathryn A

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E3 ubiquitin ligases as T cell anergy factors von Mueller, Daniel L

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Recognition of Amino Acid Motifs, Rather Than Specific Proteins, by Human Plasma Cell–Derived Monoclonal Antibodies to Posttranslationally Modified Proteins in Rheumatoid Arthritis... von Steen, Johanna, Forsström, Björn, Sahlström, Peter, Odowd, Victoria, Israelsson, Lena, Krishnamurthy, Akilan, Badreh, Sara, Mathsson Alm, Linda, Compson, Joanne, Ramsköld, Daniel, Ndlovu, Welcome, Rapecki, Stephen, Hansson, Monika, Titcombe, Philip J., Bang, Holger, Mueller, Daniel L., Catrina, Anca I., Grönwall, Caroline, Skriner, Karl, Nilsson, Peter, Lightwood, Daniel, Klareskog, Lars, Malmström, Vivianne

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Different Hierarchies of Anti–Modified Protein Autoantibody Reactivities in Rheumatoid Arthritis von Sahlström, Peter, Hansson, Monika, Steen, Johanna, Amara, Khaled, Titcombe, Philip J., Forsström, Björn, Stålesen, Ragnhild, Israelsson, Lena, Piccoli, Luca, Lundberg, Karin, Klareskog, Lars, Mueller, Daniel L., Catrina, Anca I., Skriner, Karl, Malmström, Vivianne, Grönwall, Caroline

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Pathogenic Citrulline‐Multispecific B Cell Receptor Clades in Rheumatoid Arthritis von Titcombe, Philip J., Wigerblad, Gustaf, Sippl, Natalie, Zhang, Na, Shmagel, Anna K., Sahlström, Peter, Zhang, Yue, Barsness, Laura O., Ghodke‐Puranik, Yogita, Baharpoor, Azar, Hansson, Monika, Israelsson, Lena, Skriner, Karl, Niewold, Timothy B., Klareskog, Lars, Svensson, Camilla I., Amara, Khaled, Malmström, Vivianne, Mueller, Daniel L.

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Variable domain N‐linked glycosylation and negative surface charge are key features of monoclonal ACPA: Implications for B‐cell selection von Lloyd, Katy A., Steen, Johanna, Amara, Khaled, Titcombe, Philip J., Israelsson, Lena, Lundström, Susanna L., Zhou, Diana, Zubarev, Roman A., Reed, Evan, Piccoli, Luca, Gabay, Cem, Lanzavecchia, Antonio, Baeten, Dominique, Lundberg, Karin, Mueller, Daniel L., Klareskog, Lars, Malmström, Vivianne, Grönwall, Caroline

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Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis von Lloyd, Katy A, Wigerblad, Gustaf, Sahlström, Peter, Garimella, Manasa G, Chemin, Karine, Steen, Johanna, Titcombe, Philip J, Marklein, Bianka, Zhou, Diana, Stålesen, Ragnhild, Ossipova, Elena, Lundqvist, Christina, Ekwall, Olov, Rönnelid, Johan, Mueller, Daniel L, Karlsson, Mikael C I, Kaplan, Mariana J, Skriner, Karl, Klareskog, Lars, Wermeling, Fredrik, Malmström, Vivianne, Grönwall, Caroline

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Alum adjuvant is more effective than MF59 in promoting early germinal center formation in response to peptide-protein conjugates and enhancing efficacy of candidate vaccines agains... von Pravetoni, Marco, Robinson, Christine, Schmiel, Shirdi E., Mueller, Daniel L.

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Visualizing the First 50 Hr of the Primary Immune Response to a Soluble Antigen von Catron, Drew M., Itano, Andrea A., Pape, Kathryn A., Mueller, Daniel L., Jenkins, Marc K.

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PAD4-Independent Interaction of ACPA with Nuclear Antigens in Apoptotic Cells and Neutrophil Extracellular Traps (NETs) Defines a Subset of Autoantibodies von Wigerblad, Gustaf, Lloyd, Katy A., Sahlström, Peter, Chemin, Karine, Steen, Johanna, Titcombe, Philip J., Zhou, Diana, Stalesen, Ragnhild, Marklein, Bianka, Ossipova, Elena, Rönnelid, Johan, Piccoli, Luca, Lanzavecchia, Antonio, Mueller, Daniel L., Skriner, Karl, Klareskog, Lars, Wermeling, Fredrik, Malmström, Vivianne, Grönwall, Caroline

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Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4$^+$ T Cells von Li, Wei, Whaley, Carmella D., Mondino, Anna, Mueller, Daniel L.

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A2.33 Citrullinated self antigen-specific blood B cells carry cross-reactive immunoglobulins with effector potential von Titcombe, PJ, Amara, K, Barsness, LO, Zhang, N, Krishnamurthy, A, Shmagel, A, Hansson, M, Israelsson, L, Sahlström, P, Giacobbe, L, Catrina, AI, Gillespie, EC, Klareskog, L, Peterson, EJ, Malmström, V, Mueller, DL

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Citrulline-Multispecific B Cell Receptor Clades in Rheumatoid Arthritis von Titcombe, PJ, Sippl, N, Hansson, M, Israelsson, L, Amara, K, Niewold, TB, Klareskog, L, Malmstrom, V, Mueller, DL

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Antagonistic Roles for CTLA-4 and the Mammalian Target of Rapamycin in the Regulation of Clonal Anergy: Enhanced Cell Cycle Progression Promotes Recall Antigen Responsiveness von Vanasek, Tracy L, Khoruts, Alexander, Zell, Traci, Mueller, Daniel L

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T cells: A proliferation of costimulatory molecules von Mueller, Daniel L

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Cutting Edge: B7/CD28 Interactions Regulate Cell Cycle Progression Independent of the Strength of TCR Signaling von Bonnevier, Jody L, Mueller, Daniel L

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Individual RA-Derived Monoclonal Anti-Citrullinated Protein Autoantibodies (ACPA) Have Extensive Citrulline Multi-Reactivity Demonstrated By a Large-Scale Protein Array Platform von Sahlstrom, P, Steen, J, Jenning, M, Titcombe, PJ, Nonhoff, U, Stalesen, R, Marklein, B, Mueller, DL, Konthur, Z, Lundberg, K, Catrina, AI, Klareskog, L, Malmstrom, V, Skriner, K, Gronwall, C

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Clonal Expansion Versus Functional Clonal Inactivation: A Costimulatory Signalling Pathway Determines the Outcome of T Cell Antigen Receptor Occupancy von Mueller, D L, Jenkins, M K, Schwartz, R H

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Tuning the immune system: competing positive and negative feedback loops von Mueller, Daniel L

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Single-Cell Analysis of Signal Transduction in CD4 T Cells Stimulated by Antigen in vivo von Zell, Traci, Khoruts, Alexander, Ingulli, Elizabeth, Bonnevier, Jody L., Mueller, Daniel L., Jenkins, Marc K.

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