A caged E3 ligase ligand for PROTAC-mediated protein degradation with light von Kounde, C, Shchepinova, M, Saunders, C, Muelbaier, M, Rackham, M, Harling, J, Tate, E

Volltext

ELR510444, a novel microtubule disruptor with multiple mechanisms of action von Risinger, A L, Westbrook, C D, Encinas, A, Mülbaier, M, Schultes, C M, Wawro, S, Lewis, J D, Janssen, B, Giles, F J, Mooberry, S L

Volltext

A caged E3 ligase ligand for PROTAC-mediated protein degradation with light von Kounde, Cyrille S, Shchepinova, Maria M, Saunders, Charlie N, Muelbaier, Marcel, Rackham, Mark D, Harling, John D, Tate, Edward W

Volltext

Design of amidobenzimidazole STING receptor agonists with systemic activity von Ramanjulu, Joshi M., Pesiridis, G. Scott, Yang, Jingsong, Concha, Nestor, Singhaus, Robert, Zhang, Shu-Yun, Tran, Jean-Luc, Moore, Patrick, Lehmann, Stephanie, Eberl, H. Christian, Muelbaier, Marcel, Schneck, Jessica L., Clemens, Jim, Adam, Michael, Mehlmann, John, Romano, Joseph, Morales, Angel, Kang, James, Leister, Lara, Graybill, Todd L., Charnley, Adam K., Ye, Guosen, Nevins, Neysa, Behnia, Kamelia, Wolf, Amaya I., Kasparcova, Viera, Nurse, Kelvin, Wang, Liping, Puhl, Ana C., Li, Yue, Klein, Michael, Hopson, Christopher B., Guss, Jeffrey, Bantscheff, Marcus, Bergamini, Giovanna, Reilly, Michael A., Lian, Yiqian, Duffy, Kevin J., Adams, Jerry, Foley, Kevin P., Gough, Peter J., Marquis, Robert W., Smothers, James, Hoos, Axel, Bertin, John

Volltext

Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis von Savitski, Mikhail M., Zinn, Nico, Faelth-Savitski, Maria, Poeckel, Daniel, Gade, Stephan, Becher, Isabelle, Muelbaier, Marcel, Wagner, Anne J., Strohmer, Katrin, Werner, Thilo, Melchert, Stephanie, Petretich, Massimo, Rutkowska, Anna, Vappiani, Johanna, Franken, Holger, Steidel, Michael, Sweetman, Gavain M., Gilan, Omer, Lam, Enid Y.N., Dawson, Mark A., Prinjha, Rab K., Grandi, Paola, Bergamini, Giovanna, Bantscheff, Marcus

Volltext

Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat von Becher, Isabelle, Werner, Thilo, Doce, Carola, Zaal, Esther A, Tögel, Ina, Khan, Crystal A, Rueger, Anne, Muelbaier, Marcel, Salzer, Elsa, Berkers, Celia R, Fitzpatrick, Paul F, Bantscheff, Marcus, Savitski, Mikhail M

Volltext

Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor von Thomson, Douglas W, Poeckel, Daniel, Zinn, Nico, Rau, Christina, Strohmer, Katrin, Wagner, Anne J, Graves, Alan P, Perrin, Jessica, Bantscheff, Marcus, Duempelfeld, Birgit, Kasparcova, Viera, Ramanjulu, Joshi M, Pesiridis, G. Scott, Muelbaier, Marcel, Bergamini, Giovanna

Volltext

A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level von Rutkowska, Anna, Thomson, Douglas W, Vappiani, Johanna, Werner, Thilo, Mueller, Katrin M, Dittus, Lars, Krause, Jana, Muelbaier, Marcel, Bergamini, Giovanna, Bantscheff, Marcus

Volltext

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3‑Amino-4-pyridine Carboxylate Derivatives von Westaway, Susan M, Preston, Alex G. S, Barker, Michael D, Brown, Fiona, Brown, Jack A, Campbell, Matthew, Chung, Chun-wa, Diallo, Hawa, Douault, Clement, Drewes, Gerard, Eagle, Robert, Gordon, Laurie, Haslam, Carl, Hayhow, Thomas G, Humphreys, Philip G, Joberty, Gerard, Katso, Roy, Kruidenier, Laurens, Leveridge, Melanie, Liddle, John, Mosley, Julie, Muelbaier, Marcel, Randle, Rebecca, Rioja, Inma, Rueger, Anne, Seal, Gail A, Sheppard, Robert J, Singh, Onkar, Taylor, Joanna, Thomas, Pamela, Thomson, Douglas, Wilson, David M, Lee, Kevin, Prinjha, Rab K

Volltext

Interrogating the Druggability of the 2‑Oxoglutarate-Dependent Dioxygenase Target Class by Chemical Proteomics von Joberty, Gérard, Boesche, Markus, Brown, Jack A, Eberhard, Dirk, Garton, Neil S, Humphreys, Philip G, Mathieson, Toby, Muelbaier, Marcel, Ramsden, Nigel G, Reader, Valérie, Rueger, Anne, Sheppard, Robert J, Westaway, Susan M, Bantscheff, Marcus, Lee, Kevin, Wilson, David M, Prinjha, Rab K, Drewes, Gerard

Volltext

Author Correction: Design of amidobenzimidazole STING receptor agonists with systemic activity von Ramanjulu, Joshi M., Pesiridis, G. Scott, Yang, Jingsong, Concha, Nestor, Singhaus, Robert, Zhang, Shu-Yun, Tran, Jean-Luc, Moore, Patrick, Lehmann, Stephanie, Eberl, H. Christian, Muelbaier, Marcel, Schneck, Jessica L., Clemens, Jim, Adam, Michael, Mehlmann, John, Romano, Joseph, Morales, Angel, Kang, James, Leister, Lara, Graybill, Todd L., Charnley, Adam K., Ye, Guosen, Nevins, Neysa, Behnia, Kamelia, Wolf, Amaya I., Kasparcova, Viera, Nurse, Kelvin, Wang, Liping, Puhl, Ana C., Li, Yue, Klein, Michael, Hopson, Christopher B., Guss, Jeffrey, Bantscheff, Marcus, Bergamini, Giovanna, Reilly, Michael A., Lian, Yiqian, Duffy, Kevin J., Adams, Jerry, Foley, Kevin P., Gough, Peter J., Marquis, Robert W., Smothers, James, Hoos, Axel, Bertin, John

Volltext

Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat von Becher, Isabelle, Werner, Thilo, Doce, Carola, Zaal, Esther A, Tögel, Ina, Khan, Crystal A, Rueger, Anne, Muelbaier, Marcel, Salzer, Elsa, Berkers, Celia R, Fitzpatrick, Paul F, Bantscheff, Marcus, Savitski, Mikhail M

Volltext

ELR510444 inhibits tumor growth and angiogenesis by abrogating HIF activity and disrupting microtubules in renal cell carcinoma von Carew, Jennifer S, Esquivel, 2nd, Juan A, Espitia, Claudia M, Schultes, Christoph M, Mülbaier, Marcel, Lewis, Joe D, Janssen, Bernd, Giles, Francis J, Nawrocki, Steffan T

Volltext