New Genetically Engineered Derivatives of Antibacterial Darobactins Underpin Their Potential for Antibiotic Development von Seyfert, Carsten E., Müller, Alison V., Walsh, Danica J., Birkelbach, Joy, Kany, Andreas M., Porten, Christoph, Yuan, Biao, Krug, Daniel, Herrmann, Jennifer, Marlovits, Thomas C., Hirsch, Anna K. H., Müller, Rolf

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In Vivo Activity Profiling of Biosynthetic Darobactin D22 against Critical Gram-Negative Pathogens von Kany, Andreas M., Fries, Franziska, Seyfert, Carsten E., Porten, Christoph, Deckarm, Selina, Chacón Ortiz, María, Dubarry, Nelly, Vaddi, Swapna, Große, Miriam, Bernecker, Steffen, Sandargo, Birthe, Müller, Alison V., Bacqué, Eric, Stadler, Marc, Herrmann, Jennifer, Müller, Rolf

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Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment Hit von Gerstenberger, Brian S, Trzupek, John D, Tallant, Cynthia, Fedorov, Oleg, Filippakopoulos, Panagis, Brennan, Paul E, Fedele, Vita, Martin, Sarah, Picaud, Sarah, Rogers, Catherine, Parikh, Mihir, Taylor, Alexandria, Samas, Brian, O’Mahony, Alison, Berg, Ellen, Pallares, Gabriel, Torrey, Adam D, Treiber, Daniel K, Samardjiev, Ivan J, Nasipak, Brian T, Padilla-Benavides, Teresita, Wu, Qiong, Imbalzano, Anthony N, Nickerson, Jeffrey A, Bunnage, Mark E, Müller, Susanne, Knapp, Stefan, Owen, Dafydd R

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A whole blood–based perfusate provides superior preservation of myocardial function during ex vivo heart perfusion von White, Christopher W., MD, Hasanally, Devin, BS, Mundt, Paul, BS, Li, Yun, MD, Xiang, Bo, DMD, Klein, Julianne, MD, Müller, Alison, MS, Ambrose, Emma, BS, Ravandi, Amir, MD, PhD, Arora, Rakesh C., MD, PhD, Lee, Trevor W., MD, Hryshko, Larry V., PhD, Large, Stephen, MD, Tian, Ganghong, MD, PhD, Freed, Darren H., MD, PhD

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WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop von Agajanian, Megan J., Walker, Matthew P., Axtman, Alison D., Ruela-de-Sousa, Roberta R., Serafin, D. Stephen, Rabinowitz, Alex D., Graham, David M., Ryan, Meagan B., Tamir, Tigist, Nakamichi, Yuko, Gammons, Melissa V., Bennett, James M., Couñago, Rafael M., Drewry, David H., Elkins, Jonathan M., Gileadi, Carina, Gileadi, Opher, Godoi, Paulo H., Kapadia, Nirav, Müller, Susanne, Santiago, André S., Sorrell, Fiona J., Wells, Carrow I., Fedorov, Oleg, Willson, Timothy M., Zuercher, William J., Major, Michael B.

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Extracellular and intracellular proteases in cardiac dysfunction due to ischemia–reperfusion injury von Müller, Alison L, Hryshko, Larry V, Dhalla, Naranjan S

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Steroids Limit Myocardial Edema During Ex Vivo Perfusion of Hearts Donated After Circulatory Death von Sandha, Jaskiran K., White, Christopher W., Müller, Alison, Avery, Emma, Thliveris, James, Dixon, Ian M.C., Arora, Rakesh C., Tian, Ganghong, Hryshko, Larry V., Nagendran, Jayan, Freed, Darren H.

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Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease von Song, Ci, Burgess, Stephen, Eicher, John D, O'Donnell, Christopher J, Johnson, Andrew D

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Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use von Jiang, Yu, Hughey, Jordan M., Zhan, Xiaowei, Gong, Jian, Batini, Chiara, Liu, MengZhen, Surendran, Praveen, Young, Robin, Nielsen, Sune Fallgaard, Kontto, Jukka, Perola, Markus, Caslake, Muriel, Reily, Dermot F., Vogt, Thomas, Sattar, Naveed, Ford, Ian, Alam, Dewan S., Majumder, Abdulla al Shafi, Di Angelantonio, Emanuele, Chowdhury, Rajiv, Arveiler, Dominique, Blankenberg, Stefan, Veronesi, Giovanni, EPIC-CVD Consortium, Frossard, Philippe, Nordestgaard, Børge Grønne, Saleheen, Danish, Danesh, John, Butterworth, Adam S., Warren, Helen R., Tragante, Vinicius, Altmaier, Elisabeth, Luan, Jian’an, Scott, Robert A., Stirrups, Kathleen, Marouli, Eirini, Karpe, Fredrik, Poulter, Neil, Rolandsson, Olov, Chambers, John C., Kooner, Jaspal S., Wareham, Nicholas J., Renström, Frida, Hallmans, Göran, Marioni, Riccardo E., Corley, Janie, Starr, John M., van der Meer, Peter, Yavas, Ersin, Vaartjes, Ilonca, Asselbergs, Folkert W., Grabe, Hans J., Nauck, Matthias, Pharoah, Paul D.P., Dunning, Alison M., Dennis, Joe G., Tyrrell, Jessica, Mihailov, Evelin, Metspalu, Andres, Palmer, Colin N.A., Hall, Ian P., Strachan, David P., Understanding Society Scientific Group, Munroe, Patricia B., Jansson, Jan-Håkan, Franks, Paul W., Deloukas, Panos, Chou, Yi-Ling, Faul, Jessica D., Hammerschlag, Anke R., Hsu, Chris, Lai, Dongbing, Le, Nhung, Loukola, Anu, Mangino, Massimo, Melbourne, Carl A., Pistis, Giorgio, Qaiser, Beenish, Stringham, Heather, Wetherill, Leah, Bierut, Laura, Chen, Chu, Eaton, Charles B., Iacono, William G., Polderman, Tinca J., Schlessinger, David, Scholte, H. Steven, Smith, Jennifer A., Boehnke, Michael, Cucca, Francesco, David, Sean P., Foroud, Tatiana, Kardia, Sharon L.R., Madden, Pamela, McGue, Matt, Posthuma, Danielle, Spector, Timothy, Stram, Daniel, Kaprio, Jaakko, Vrieze, Scott

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Multinational evidence-based recommendations for the diagnosis and management of gout: integrating systematic literature review and expert opinion of a broad panel of rheumatologis... von Sivera, Francisca, Andrés, Mariano, Carmona, Loreto, Kydd, Alison S R, Moi, John, Seth, Rakhi, Sriranganathan, Melonie, van Durme, Caroline, van Echteld, Irene, Vinik, Ophir, Wechalekar, Mihir D, Aletaha, Daniel, Bombardier, Claire, Buchbinder, Rachelle, Edwards, Christopher J, Landewé, Robert B, Bijlsma, Johannes W, Branco, Jaime C, Burgos-Vargas, Rubén, Catrina, Anca I, Elewaut, Dirk, Ferrari, Antonio J L, Kiely, Patrick, Leeb, Burkhard F, Montecucco, Carlomaurizio, Müller-Ladner, Ulf, Østergaard, Mikkel, Zochling, Jane, Falzon, Louise, van der Heijde, Désirée M

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ALMA Observations of the Physical and Chemical Conditions in Centaurus A von McCoy, Mark, Ott, Jürgen, Meier, David S., Muller, Sébastien, Espada, Daniel, Martín, Sergio, Israel, Frank P., Henkel, Christian, Impellizzeri, Violette, Aalto, Susanne, Edwards, Philip G., Brunthaler, Andreas, Neumayer, Nadine, Peck, Alison B., van der Werf, Paul, Feain, Ilana

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Cost-effectiveness of Spironolactone for Adult Female Acne (SAFA): economic evaluation alongside a randomised controlled trial von Pyne, Sarah, Sach, Tracey H, Lawrence, Megan, Renz, Susanne, Eminton, Zina, Stuart, Beth, Thomas, Kim S, Francis, Nick, Soulsby, Irene, Thomas, Karen, Permyakova, Natalia V, Ridd, Matthew J, Little, Paul, Muller, Ingrid, Nuttall, Jacqui, Griffiths, Gareth, Layton, Alison M, Santer, Miriam

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Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer von von Minckwitz, Gunter, Huang, Chiun-Sheng, Mano, Max S, Loibl, Sibylle, Mamounas, Eleftherios P, Untch, Michael, Wolmark, Norman, Rastogi, Priya, Schneeweiss, Andreas, Redondo, Andres, Fischer, Hans H, Jacot, William, Conlin, Alison K, Arce-Salinas, Claudia, Wapnir, Irene L, Jackisch, Christian, DiGiovanna, Michael P, Fasching, Peter A, Crown, John P, Wülfing, Pia, Shao, Zhimin, Rota Caremoli, Elena, Wu, Haiyan, Lam, Lisa H, Tesarowski, David, Smitt, Melanie, Douthwaite, Hannah, Singel, Stina M, Geyer, Charles E

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The MIRI Medium Resolution Spectrometer calibration pipeline von Labiano, A., Azzollini, R., Bailey, J., Beard, S., Dicken, D., Garcia-Marin, M., Geers, V. C., Glasse, A., Glauser, A. M., Gordon, K., Justtanont, Kay, Klaassen, P., Lahuis, F., Law, D., Morrison, J. E., Müller, M., Rieke, G. H., Vandenbussche, B., Wright, G.

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HighVia—A Flexible Live-Cell High-Content Screening Pipeline to Assess Cellular Toxicity von Howarth, Alison, Schröder, Martin, Montenegro, Raquel C., Drewry, David H., Sailem, Heba, Millar, Val, Müller, Susanne, Ebner, Daniel V.

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Prognostic Importance of Promoter Hypermethylation of Multiple Genes in Esophageal Adenocarcinoma von Brock, Malcolm V, Gou, Mingzhou, Akiyama, Yoshimitsu, Muller, Alison, Wu, Tsung-Teh, Montgomery, Elizabeth, Deasel, Mari, Germonpré, Paul, Rubinson, Lewis, Heitmiller, Richard F, Yang, Stephen C, Forastiere, Arlene A, Baylin, Stephen B, Herman, James G

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An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis von Smith, Harvey W., Hirukawa, Alison, Sanguin-Gendreau, Virginie, Nandi, Ipshita, Dufour, Catherine R., Zuo, Dongmei, Tandoc, Kristofferson, Leibovitch, Matthew, Singh, Salendra, Rennhack, Jonathan P., Swiatnicki, Matthew, Lavoie, Cynthia, Papavasiliou, Vasilios, Temps, Carolin, Carragher, Neil O., Unciti-Broceta, Asier, Savage, Paul, Basik, Mark, van Hoef, Vincent, Larsson, Ola, Cooper, Caroline L., Vargas Calderon, Ana Cristina, Beith, Jane, Millar, Ewan, Selinger, Christina, Giguère, Vincent, Park, Morag, Harris, Lyndsay N., Varadan, Vinay, Andrechek, Eran R., O’Toole, Sandra A., Topisirovic, Ivan, Muller, William J.

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The Circumnuclear Molecular Gas in the Seyfert Galaxy NGC 4945 von Chou, Richard C. Y, Peck, A. B, Lim, J, Matsushita, S, Muller, S, Sawada-Satoh, S, Dinh-V-Trung, Boone, F, Henkel, C

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A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers von Coignard, Juliette, Dennis, Joe, Tyrer, Jonathan P., McGuffog, Lesley, Bolla, Manjeet K., Adank, Muriel A., Ahearn, Thomas, Aittomäki, Kristiina, Andrulis, Irene L., Anton-Culver, Hoda, Arndt, Volker, Arun, Banu K., Baynes, Caroline, Becher, Heiko, Bernstein, Leslie, Białkowska, Katarzyna, Blomqvist, Carl, Bojesen, Stig E., Brenner, Hermann, Buys, Saundra S., Caligo, Maria A., Castelao, Jose E., Chang-Claude, Jenny, Chanock, Stephen J., Chung, Wendy K., Collée, J. Margriet, Czene, Kamila, Devilee, Peter, Dwek, Miriam, Evans, D. Gareth, Flyger, Henrik, Fostira, Florentia, García-Closas, Montserrat, García-Sáenz, José A., Gaudet, Mia M., Gehrig, Andrea, Giles, Graham G., Goldgar, David E., Guénel, Pascal, Haeberle, Lothar, Haiman, Christopher A., Hall, Per, Hamann, Ute, Harrington, Patricia A., Hart, Steven N., He, Wei, Hogervorst, Frans B. L., Hollestelle, Antoinette, Hulick, Peter J., Hunter, David J., Jager, Agnes, Jones, Michael E., Kaaks, Rudolf, Kapoor, Pooja Middha, Karlan, Beth Y., Keeman, Renske, Kiiski, Johanna I., Kraft, Peter, Lambrechts, Diether, Lesueur, Fabienne, Lindstrom, Tricia, Mannermaa, Arto, Meindl, Alfons, Montagna, Marco, Nathanson, Katherine L., Neuhausen, Susan L., Nevanlinna, Heli, O’Brien, Katie M., Olsson, Håkan, Ottini, Laura, Park-Simon, Tjoung-Won, Pedersen, Inge Sokilde, Peterlongo, Paolo, Peto, Julian, Pharoah, Paul D. P., Polley, Eric C., Pujana, Miquel Angel, Punie, Kevin, Rashid, Muhammad U., Rennert, Gad, Saloustros, Emmanouil, Santella, Regina, Scheuner, Maren T., Schmidt, Gunnar, Scott, Christopher, Swerdlow, Anthony, Tamimi, Rulla M., Taylor, Jack A., Thull, Darcy L., Tung, Nadine, Vachon, Celine M., Vega, Ana, Wang, Qin, Wendt, Camilla, Yang, Xiaohong R., Ziogas, Argyrios, Park, Sue K., Thomassen, Mads, Simard, Jacques, Chenevix-Trench, Georgia

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Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk von Lin, Wei-Yu, Camp, Nicola J, Ghoussaini, Maya, Beesley, Jonathan, Michailidou, Kyriaki, Hopper, John L, Apicella, Carmel, Southey, Melissa C, Stone, Jennifer, Schmidt, Marjanka K, Broeks, Annegien, Van't Veer, Laura J, Th Rutgers, Emiel J, Muir, Kenneth, Lophatananon, Artitaya, Stewart-Brown, Sarah, Siriwanarangsan, Pornthep, Fasching, Peter A, Haeberle, Lothar, Ekici, Arif B, Beckmann, Matthias W, Peto, Julian, Dos-Santos-Silva, Isabel, Fletcher, Olivia, Johnson, Nichola, Bolla, Manjeet K, Wang, Qin, Dennis, Joe, Sawyer, Elinor J, Cheng, Timothy, Tomlinson, Ian, Kerin, Michael J, Miller, Nicola, Marmé, Frederik, Surowy, Harald M, Burwinkel, Barbara, Guénel, Pascal, Truong, Thérèse, Menegaux, Florence, Mulot, Claire, Bojesen, Stig E, Nordestgaard, Børge G, Nielsen, Sune F, Flyger, Henrik, Benitez, Javier, Zamora, M Pilar, Arias Perez, Jose Ignacio, Menéndez, Primitiva, González-Neira, Anna, Pita, Guillermo, Alonso, M Rosario, Alvarez, Nuria, Herrero, Daniel, Anton-Culver, Hoda, Brenner, Hermann, Dieffenbach, Aida Karina, Arndt, Volker, Stegmaier, Christa, Meindl, Alfons, Lichtner, Peter, Schmutzler, Rita K, Müller-Myhsok, Bertram, Brauch, Hiltrud, Brüning, Thomas, Ko, Yon-Dschun, Tessier, Daniel C, Vincent, Daniel, Bacot, Francois, Nevanlinna, Heli, Aittomäki, Kristiina, Blomqvist, Carl, Khan, Sofia, Matsuo, Keitaro, Ito, Hidemi, Iwata, Hiroji, Horio, Akiyo, Bogdanova, Natalia V, Antonenkova, Natalia N, Dörk, Thilo, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M, Wu, Anna H, Tseng, Chiu-Chen, Van Den Berg, David, Stram, Daniel O, Neven, Patrick, Wauters, Els, Wildiers, Hans, Lambrechts, Diether, Chang-Claude, Jenny, Rudolph, Anja, Seibold, Petra, Flesch-Janys, Dieter, Radice, Paolo, Peterlongo, Paolo, Manoukian, Siranoush

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