A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity von Compte, Marta, Harwood, Seandean Lykke, Muñoz, Ines G., Navarro, Rocio, Zonca, Manuela, Perez-Chacon, Gema, Erce-Llamazares, Ainhoa, Merino, Nekane, Tapia-Galisteo, Antonio, Cuesta, Angel M., Mikkelsen, Kasper, Caleiras, Eduardo, Nuñez-Prado, Natalia, Aznar, M. Angela, Lykkemark, Simon, Martínez-Torrecuadrada, Jorge, Melero, Ignacio, Blanco, Francisco J., Bernardino de la Serna, Jorge, Zapata, Juan M., Sanz, Laura, Alvarez-Vallina, Luis

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An Fc-free EGFR-specific 4-1BB-agonistic Trimerbody Displays Broad Antitumor Activity in Humanized Murine Cancer Models without Toxicity von Compte, Marta, Harwood, Seandean L, Erce-Llamazares, Ainhoa, Tapia-Galisteo, Antonio, Romero, Eduardo, Ferrer, Irene, Garrido-Martin, Eva M, Enguita, Ana B, Ochoa, Maria C, Blanco, Belén, Oteo, Marta, Merino, Nekane, Nehme-Álvarez, Daniel, Hangiu, Oana, Domínguez-Alonso, Carmen, Zonca, Manuela, Ramírez-Fernández, Angel, Blanco, Francisco J, Morcillo, Miguel A, Muñoz, Ines G, Melero, Ignacio, Rodriguez-Peralto, José L, Paz-Ares, Luis, Sanz, Laura, Alvarez-Vallina, Luis

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An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function von Cuesta-Hernández, Hipólito Nicolás, Contreras, Julia, Soriano-Maldonado, Pablo, Sánchez-Wandelmer, Jana, Yeung, Wayland, Martín-Hurtado, Ana, Muñoz, Inés G., Kannan, Natarajan, Llimargas, Marta, Muñoz, Javier, Plaza-Menacho, Iván

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Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases von Blanco, Francisco J, Prieto, Jesús, Arnould, Sylvain, Daboussi, Fayza, Redondo, Pilar, Perez, Christophe, Muñoz, Inés G, Duchateau, Philippe, Pâques, Frédéric, Alibés, Andreu, Montoya, Guillermo, Stricher, Francois, Serrano, Luis, Cabaniols, Jean-Pierre

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Chaperonins: two rings for folding von Yébenes, Hugo, Mesa, Pablo, Muñoz, Inés G., Montoya, Guillermo, Valpuesta, José M.

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Recommendations for the classification of germline variants in the exonuclease domain of POLE and POLD1 von Mur, Pilar, Viana-Errasti, Julen, García-Mulero, Sandra, Magraner-Pardo, Lorena, Muéoz, Inés G, Pons, Tirso, Capellá, Gabriel, Pineda, Marta, Feliubadaló, Lidia, Valle, Laura

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Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin von Valpuesta, José M, Montoya, Guillermo, Muñoz, Inés G, Yébenes, Hugo, Zhou, Min, Mesa, Pablo, Serna, Marina, Park, Ah Young, Bragado-Nilsson, Elisabeth, Beloso, Ana, de Cárcer, Guillermo, Malumbres, Marcos, Robinson, Carol V

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Molecular basis of the final step of cell division in Streptococcus pneumoniae von Martínez-Caballero, Siseth, Freton, Céline, Molina, Rafael, Bartual, Sergio G., Gueguen-Chaignon, Virginie, Mercy, Chryslène, Gago, Federico, Mahasenan, Kiran V., Muñoz, Inés G., Lee, Mijoon, Hesek, Dusan, Mobashery, Shahriar, Hermoso, Juan A., Grangeasse, Christophe

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A mechanism for cancer‐associated inactivation of NQO1 due to P187S and its reactivation by the consensus mutation H80R von Muñoz, Inés G., Morel, Bertrand, Medina‐Carmona, Encarnación, Pey, Angel L.

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Molecular basis of Tousled-Like Kinase 2 activation von Mortuza, Gulnahar B., Hermida, Dario, Pedersen, Anna-Kathrine, Segura-Bayona, Sandra, López-Méndez, Blanca, Redondo, Pilar, Rüther, Patrick, Pozdnyakova, Irina, Garrote, Ana M., Muñoz, Inés G., Villamor-Payà, Marina, Jauset, Cristina, Olsen, Jesper V., Stracker, Travis H., Montoya, Guillermo

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Structural basis of PcsB-mediated cell separation in Streptococcus pneumoniae von Bartual, Sergio G., Straume, Daniel, Stamsås, Gro Anita, Muñoz, Inés G., Alfonso, Carlos, Martínez-Ripoll, Martín, Håvarstein, Leiv Sigve, Hermoso, Juan A.

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Structural and biochemical insights into an engineered high-redox potential laccase overproduced in Aspergillus von de Salas, Felipe, Cañadas, Rubén, Santiago, Gerard, Virseda-Jerez, Alicia, Vind, Jesper, Gentili, Patrizia, Martínez, Angel T., Guallar, Víctor, Muñoz, Inés G., Camarero, Susana

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Homing endonucleases: from basics to therapeutic applications von Marcaida, Maria J, Muñoz, Inés G, Blanco, Francisco J, Prieto, Jesús, Montoya, Guillermo

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Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus von Muñoz, Inés G, Prieto, Jesús, Subramanian, Sunita, Coloma, Javier, Redondo, Pilar, Villate, Maider, Merino, Nekane, Marenchino, Marco, D'Abramo, Marco, Gervasio, Francesco L, Grizot, Sylvestre, Daboussi, Fayza, Smith, Julianne, Chion-Sotinel, Isabelle, Pâques, Frédéric, Duchateau, Philippe, Alibés, Andreu, Stricher, François, Serrano, Luis, Blanco, Francisco J, Montoya, Guillermo

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Small molecule MMRi62 targets MDM4 for degradation and induces leukemic cell apoptosis regardless of p53 status von Lama, Rati, Xu, Chao, Galster, Samuel L, Querol-García, Javier, Portwood, Scott, Mavis, Cory K, Ruiz, Federico M, Martin, Diana, Wu, Jin, Giorgi, Marianna C, Bargonetti, Jill, Wang, Eunice S, Hernandez-Ilizaliturri, Francisco J, Koudelka, Gerald B, Chemler, Sherry R, Muñoz, Inés G, Wang, Xinjiang

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Experimental and computational evidence on conformational fluctuations as a source of catalytic defects in genetic diseases von Fuchs, Julian E, Muñoz, Inés G, Timson, David J, Pey, Angel L

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Molecular Basis of Histone H3K4me3 Recognition by ING4 von Palacios, Alicia, Muñoz, Inés G., Pantoja-Uceda, David, Marcaida, María J., Torres, Daniel, Martín-García, José M., Luque, Irene, Montoya, Guillermo, Blanco, Francisco J.

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Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus, an essential component of the divisome machinery von Martínez-Caballero, Siseth, Mahasenan, Kiran V., Kim, Choon, Molina, Rafael, Feltzer, Rhona, Lee, Mijoon, Bouley, Renee, Hesek, Dusan, Fisher, Jed F., Muñoz, Inés G., Chang, Mayland, Mobashery, Shahriar, Hermoso, Juan A.

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Crystal Structure of Inhibitor of Growth 4 (ING4) Dimerization Domain Reveals Functional Organization of ING Family of Chromatin-binding Proteins von Culurgioni, Simone, Muñoz, Inés G., Moreno, Alberto, Palacios, Alicia, Villate, Maider, Palmero, Ignacio, Montoya, Guillermo, Blanco, Francisco J.

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Activation of Nucleoplasmin, an Oligomeric Histone Chaperone, Challenges Its Stability von Taneva, Stefka G, Muñoz, Inés G, Franco, Guillermo, Falces, Jorge, Arregi, Igor, Muga, Arturo, Montoya, Guillermo, Urbaneja, María A, Bañuelos, Sonia

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