Global Nav1.7 knockout mice recapitulate the phenotype of human congenital indifference to pain von Gingras, Jacinthe, Smith, Sarah, Matson, David J, Johnson, Danielle, Nye, Kim, Couture, Lauren, Feric, Elma, Yin, Ruoyuan, Moyer, Bryan D, Peterson, Matthew L, Rottman, James B, Beiler, Rudolph J, Malmberg, Annika B, McDonough, Stefan I

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Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V von Moyer, Bryan D, Murray, Justin K, Ligutti, Joseph, Andrews, Kristin, Favreau, Philippe, Jordan, John B, Lee, Josie H, Liu, Dong, Long, Jason, Sham, Kelvin, Shi, Licheng, Stöcklin, Reto, Wu, Bin, Yin, Ruoyuan, Yu, Violeta, Zou, Anruo, Biswas, Kaustav, Miranda, Les P

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Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors von DiMauro, Erin F, Altmann, Stephen, Berry, Loren M, Bregman, Howard, Chakka, Nagasree, Chu-Moyer, Margaret, Bojic, Elma Feric, Foti, Robert S, Fremeau, Robert, Gao, Hua, Gunaydin, Hakan, Guzman-Perez, Angel, Hall, Brian E, Huang, Hongbing, Jarosh, Michael, Kornecook, Thomas, Lee, Josie, Ligutti, Joseph, Liu, Dong, Moyer, Bryan D, Ortuno, Daniel, Rose, Paul E, Schenkel, Laurie B, Taborn, Kristin, Wang, Jean, Wang, Yan, Yu, Violeta, Weiss, Matthew M

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Genome-wide analysis of gene expression in primate taste buds reveals links to diverse processes von Hevezi, Peter, Moyer, Bryan D, Lu, Min, Gao, Na, White, Evan, Echeverri, Fernando, Kalabat, Dalia, Soto, Hortensia, Laita, Bianca, Li, Cherry, Yeh, Shaoyang Anthony, Zoller, Mark, Zlotnik, Albert

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Voltage-gated sodium channels in taste bud cells von Gao, Na, Lu, Min, Echeverri, Fernando, Laita, Bianca, Kalabat, Dalia, Williams, Mark E, Hevezi, Peter, Zlotnik, Albert, Moyer, Bryan D

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Expression of genes encoding multi-transmembrane proteins in specific primate taste cell populations von Moyer, Bryan D, Hevezi, Peter, Gao, Na, Lu, Min, Kalabat, Dalia, Soto, Hortensia, Echeverri, Fernando, Laita, Bianca, Yeh, Shaoyang Anthony, Zoller, Mark, Zlotnik, Albert

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Endoplasmic Reticulum Retention, Degradation, and Aggregation of Olfactory G‐Protein Coupled Receptors von Lu, Min, Echeverri, Fernando, Moyer, Bryan D.

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Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats von Lehto, Sonya G, Weyer, Andy D, Youngblood, Beth D, Zhang, Maosheng, Yin, Ruoyuan, Wang, Weiya, Teffera, Yohannes, Cooke, Melanie, Stucky, Cheryl L, Schenkel, Laurie, Geuns-Meyer, Stephanie, Moyer, Bryan D, Wild, Kenneth D, Gavva, Narender R

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Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement von Marx, Isaac E, Dineen, Thomas A, Able, Jessica, Bode, Christiane, Bregman, Howard, Chu-Moyer, Margaret, DiMauro, Erin F, Du, Bingfan, Foti, Robert S, Fremeau, Robert T, Gao, Hua, Gunaydin, Hakan, Hall, Brian E, Huang, Liyue, Kornecook, Thomas, Kreiman, Charles R, La, Daniel S, Ligutti, Joseph, Lin, Min-Hwa Jasmine, Liu, Dong, McDermott, Jeff S, Moyer, Bryan D, Peterson, Emily A, Roberts, Jonathan T, Rose, Paul, Wang, Jean, Youngblood, Beth D, Yu, Violeta, Weiss, Matthew M

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Discovery of a biarylamide series of potent, state-dependent NaV1.7 inhibitors von Schenkel, Laurie B., DiMauro, Erin F., Nguyen, Hanh N., Chakka, Nagasree, Du, Bingfan, Foti, Robert S., Guzman-Perez, Angel, Jarosh, Michael, La, Daniel S., Ligutti, Joseph, Milgram, Benjamin C., Moyer, Bryan D., Peterson, Emily A., Roberts, John, Yu, Violeta L., Weiss, Matthew M.

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A Golgi-associated PDZ Domain Protein Modulates Cystic Fibrosis Transmembrane Regulator Plasma Membrane Expression von Cheng, Jie, Moyer, Bryan D., Milewski, Michal, Loffing, Johannes, Ikeda, Masahiro, Mickle, John E., Cutting, Garry R., Li, Min, Stanton, Bruce A., Guggino, William B.

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Non-conventional Trafficking of the Cystic Fibrosis Transmembrane Conductance Regulator through the Early Secretory Pathway von Yoo, Jin-San, Moyer, Bryan D., Bannykh, Sergei, Yoo, Hyeon-Mi, Riordan, John R., Balch, William E.

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Small Molecule Activator of the Human Epithelial Sodium Channel von Lu, Min, Echeverri, Fernando, Kalabat, Dalia, Laita, Bianca, Dahan, David S., Smith, Raymond D., Xu, Hong, Staszewski, Lena, Yamamoto, Jeff, Ling, Jing, Hwang, Nancy, Kimmich, Rachel, Li, Peter, Patron, Erika, Keung, Walter, Patron, Andrew, Moyer, Bryan D.

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Engineering Potent and Selective Analogues of GpTx-1, a Tarantula Venom Peptide Antagonist of the NaV1.7 Sodium Channel von Murray, Justin K, Ligutti, Joseph, Liu, Dong, Zou, Anruo, Poppe, Leszek, Li, Hongyan, Andrews, Kristin L, Moyer, Bryan D, McDonough, Stefan I, Favreau, Philippe, Stöcklin, Reto, Miranda, Les P

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Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel von Murray, Justin K, Ligutti, Joseph, Liu, Dong, Zou, Anruo, Poppe, Leszek, Li, Hongyan, Andrews, Kristin L, Moyer, Bryan D, McDonough, Stefan I, Favreau, Philippe, Stöcklin, Reto, Miranda, Les P

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Single Residue Substitutions That Confer Voltage-Gated Sodium Ion Channel Subtype Selectivity in the NaV1.7 Inhibitory Peptide GpTx‑1 von Murray, Justin K, Long, Jason, Zou, Anruo, Ligutti, Joseph, Andrews, Kristin L, Poppe, Leszek, Biswas, Kaustav, Moyer, Bryan D, McDonough, Stefan I, Miranda, Les P

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Discovery of pyridyl urea sulfonamide inhibitors of NaV1.7 von Butler, John R., Rescourio, Gwenaella, Milgram, Benjamin C., Foti, Robert S., Kornecook, Thomas, Ligutti, Joseph, Moyer, Bryan D., Taborn, Kristin, Youngblood, Beth D., Yu, Violeta, Shimanovich, Roman, Boezio, Alessandro, Weiss, Matthew

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Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics While Mitigating Metabolic Liabilities von Weiss, Matthew M, Dineen, Thomas A, Marx, Isaac E, Altmann, Steven, Boezio, Alessandro, Bregman, Howard, Chu-Moyer, Margaret, DiMauro, Erin F, Feric Bojic, Elma, Foti, Robert S, Gao, Hua, Graceffa, Russell, Gunaydin, Hakan, Guzman-Perez, Angel, Huang, Hongbing, Huang, Liyue, Jarosh, Michael, Kornecook, Thomas, Kreiman, Charles R, Ligutti, Joseph, La, Daniel S, Lin, Min-Hwa Jasmine, Liu, Dong, Moyer, Bryan D, Nguyen, Hanh N, Peterson, Emily A, Rose, Paul E, Taborn, Kristin, Youngblood, Beth D, Yu, Violeta, Fremeau, Robert T

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Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Viv... von Graceffa, Russell F, Boezio, Alessandro A, Able, Jessica, Altmann, Steven, Berry, Loren M, Boezio, Christiane, Butler, John R, Chu-Moyer, Margaret, Cooke, Melanie, DiMauro, Erin F, Dineen, Thomas A, Feric Bojic, Elma, Foti, Robert S, Fremeau, Robert T, Guzman-Perez, Angel, Gao, Hua, Gunaydin, Hakan, Huang, Hongbing, Huang, Liyue, Ilch, Christopher, Jarosh, Michael, Kornecook, Thomas, Kreiman, Charles R, La, Daniel S, Ligutti, Joseph, Milgram, Benjamin C, Lin, Min-Hwa Jasmine, Marx, Isaac E, Nguyen, Hanh N, Peterson, Emily A, Rescourio, Gwen, Roberts, John, Schenkel, Laurie, Shimanovich, Roman, Sparling, Brian A, Stellwagen, John, Taborn, Kristin, Vaida, Karina R, Wang, Jean, Yeoman, John, Yu, Violeta, Zhu, Dawn, Moyer, Bryan D, Weiss, Matthew M

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PAC1 receptor blockade reduces central nociceptive activity: new approach for primary headache? von Hoffmann, Jan, Miller, Silke, Martins-Oliveira, Margarida, Akerman, Simon, Supronsinchai, Weera, Sun, Hong, Shi, Licheng, Wang, Judy, Zhu, Dawn, Lehto, Sonya, Liu, Hantao, Yin, Ruoyuan, Moyer, Bryan D., Xu, Cen, Goadsby, Peter J.

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