The extracellular matrix modulates the hallmarks of cancer von Pickup, Michael W, Mouw, Janna K, Weaver, Valerie M

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Feeling Stress: The Mechanics of Cancer Progression and Aggression von Northcott, Josette M, Dean, Ivory S, Mouw, Janna K, Weaver, Valerie M

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Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair von Haradhvala, N. J., Kim, J., Maruvka, Y. E., Polak, P., Rosebrock, D., Livitz, D., Hess, J. M., Leshchiner, I., Kamburov, A., Mouw, K. W., Lawrence, M. S., Getz, G.

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The cancer glycocalyx mechanically primes integrin-mediated growth and survival von Paszek, Matthew J., DuFort, Christopher C., Rossier, Olivier, Bainer, Russell, Mouw, Janna K., Godula, Kamil, Hudak, Jason E., Lakins, Jonathon N., Wijekoon, Amanda C., Cassereau, Luke, Rubashkin, Matthew G., Magbanua, Mark J., Thorn, Kurt S., Davidson, Michael W., Rugo, Hope S., Park, John W., Hammer, Daniel A., Giannone, Grégory, Bertozzi, Carolyn R., Weaver, Valerie M.

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Subpopulation targeting of pyruvate dehydrogenase and GLUT1 decouples metabolic heterogeneity during collective cancer cell invasion von Commander, R., Wei, C., Sharma, A., Mouw, J. K., Burton, L. J., Summerbell, E., Mahboubi, D., Peterson, R. J., Konen, J., Zhou, W., Du, Y., Fu, H., Shanmugam, M., Marcus, A. I.

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Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217 von Northey, Jason J., Barrett, Alexander S., Acerbi, Irene, Hayward, Mary-Kate, Talamantes, Stephanie, Dean, Ivory S., Mouw, Janna K., Ponik, Suzanne M., Lakins, Jonathon N., Huang, Po-Jui, Wu, Junmin, Shi, Quanming, Samson, Susan, Keely, Patricia J., Mukhtar, Rita A., Liphardt, Jan T., Shepherd, John A., Hwang, E. Shelley, Chen, Yunn-Yi, Hansen, Kirk C., Littlepage, Laurie E., Weaver, Valerie M.

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Extracellular matrix assembly: a multiscale deconstruction von Mouw, Janna K., Ou, Guanqing, Weaver, Valerie M.

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A live-cell platform to isolate phenotypically defined subpopulations for spatial multi-omic profiling von Khatib, Tala O, Amanso, Angelica M, Knippler, Christina M, Pedro, Brian, Summerbell, Emily R, Zohbi, Najdat M, Konen, Jessica M, Mouw, Janna K, Marcus, Adam I

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α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site von Miroshnikova, Y A, Rozenberg, G I, Cassereau, L, Pickup, M, Mouw, J K, Ou, G, Templeman, K L, Hannachi, E-I, Gooch, K J, Sarang-Sieminski, A L, García, A J, Weaver, V M

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Retraction Note: Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin von Damiano, L., Stewart, K. M., Cohet, N., Mouw, J. K., Lakins, J. N., Debnath, J., Reisman, D., Nickerson, J. A., Imbalzano, A. N., Weaver, V. M.

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Biomechanical regulation of cell orientation and fate von Lopez, J I, Mouw, J K, Weaver, V M

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Dynamic compression regulates the expression and synthesis of chondrocyte-specific matrix molecules in bone marrow stromal cells von Mouw, Janna K, Connelly, John T, Wilson, Christopher G, Michael, Kristin E, Levenston, Marc E

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Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning von Summerbell, Emily R., Mouw, Janna K., Bell, Joshua S. K., Knippler, Christina M., Pedro, Brian, Arnst, Jamie L., Khatib, Tala O., Commander, Rachel, Barwick, Benjamin G., Konen, Jessica, Dwivedi, Bhakti, Seby, Sandra, Kowalski, Jeanne, Vertino, Paula M., Marcus, Adam

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Dynamic compression of chondrocyte-seeded fibrin gels: effects on matrix accumulation and mechanical stiffness von Hunter, Christopher J., Mouw, Janna K., Levenston, Marc E.

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Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion von Knippler, Christina M., Arnst, Jamie L., Robinson, Isaac E., Matsuk, Veronika, Khatib, Tala O., Harvey, R. Donald, Shanmugam, Mala, Mouw, Janna K., Fu, Haian, Ganesh, Thota, Marcus, Adam I.

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Intra-tumoral YAP and TAZ heterogeneity drives collective NSCLC invasion that is targeted by SUMOylation inhibitor TAK-981 von Sharma, Richa, Sharma, Shagun, Shriwas, Pratik, Mehta, Labdhi, Vu, An H., Mouw, Janna K., Koo, Junghui, Huang, Chunzi, Matsuk, Veronika Y., Tucker-Burden, Carol, Joseph, Gregory, Behera, Madhusmita, Sun, Shi-Yong, Roy, Melissa A., Gilbert-Ross, Melissa, Leal, Ticiana, Marcus, Adam I., Shanmugam, Mala

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Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression von Laklai, Hanane, Miroshnikova, Yekaterina A, Pickup, Michael W, Collisson, Eric A, Kim, Grace E, Barrett, Alex S, Hill, Ryan C, Lakins, Johnathon N, Schlaepfer, David D, Mouw, Janna K, LeBleu, Valerie S, Roy, Nilotpal, Novitskiy, Sergey V, Johansen, Julia S, Poli, Valeria, Kalluri, Raghu, Iacobuzio-Donahue, Christine A, Wood, Laura D, Hebrok, Matthias, Hansen, Kirk, Moses, Harold L, Weaver, Valerie M

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Somatic ERCC2 Mutations Are Associated With a Distinct Mutational Signature in Muscle-Invasive Bladder Cancer von Mouw, K, Braunstein, L.Z, Kim, J, Polak, P, Getz, G, D'Andrea, A.D

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Tissue mechanics promote IDH1-dependent HIF1α–tenascin C feedback to regulate glioblastoma aggression von Miroshnikova, Yekaterina A., Mouw, Janna K., Barnes, J. Matthew, Pickup, Michael W., Lakins, Johnathan N., Kim, Youngmi, Lobo, Khadjia, Persson, Anders I., Reis, Gerald F., McKnight, Tracy R., Holland, Eric C., Phillips, Joanna J., Weaver, Valerie M.

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Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression von Mouw, Janna K, Yui, Yoshihiro, Damiano, Laura, Bainer, Russell O, Lakins, Johnathon N, Acerbi, Irene, Ou, Guanqing, Wijekoon, Amanda C, Levental, Kandice R, Gilbert, Penney M, Hwang, E Shelley, Chen, Yunn-Yi, Weaver, Valerie M

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