Polyamines and eIF5A hypusination facilitate SREBP2 synthesis and cholesterol production leading to enhanced enterovirus attachment and infection von Firpo, Mason R, LoMascolo, Natalie J, Petit, Marine J, Shah, Priya S, Mounce, Bryan C

Volltext

Diverse Functions of Polyamines in Virus Infection von Firpo, Mason R., Mounce, Bryan C.

Volltext

Whole-Genome Sequencing Analysis from the Chikungunya Virus Caribbean Outbreak Reveals Novel Evolutionary Genomic Elements von Stapleford, Kenneth A, Moratorio, Gonzalo, Henningsson, Rasmus, Chen, Rubing, Matheus, Séverine, Enfissi, Antoine, Weissglas-Volkov, Daphna, Isakov, Ofer, Blanc, Hervé, Mounce, Bryan C, Dupont-Rouzeyrol, Myrielle, Shomron, Noam, Weaver, Scott, Fontes, Magnus, Rousset, Dominique, Vignuzzi, Marco

Volltext

Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses von Mounce, Bryan C., Poirier, Enzo Z., Passoni, Gabriella, Simon-Loriere, Etienne, Cesaro, Teresa, Prot, Matthieu, Stapleford, Kenneth A., Moratorio, Gonzalo, Sakuntabhai, Anavaj, Levraud, Jean-Pierre, Vignuzzi, Marco

Volltext

Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication von Tate, Patrick M., Mastrodomenico, Vincent, Mounce, Bryan C.

Volltext

Polyamine Analog Diethylnorspermidine Restricts Coxsackievirus B3 and Is Overcome by 2A Protease Mutation In Vitro von Hulsebosch, Bridget M., Mounce, Bryan C.

Volltext

Novel Ionophores Active against La Crosse Virus Identified through Rapid Antiviral Screening von Sandler, Zachary J., Firpo, Mason R., Omoba, Oreoluwa S., Vu, Michelle N., Menachery, Vineet D., Mounce, Bryan C.

Volltext

Low-Fidelity Polymerases of Alphaviruses Recombine at Higher Rates To Overproduce Defective Interfering Particles von Poirier, Enzo Z, Mounce, Bryan C, Rozen-Gagnon, Kathryn, Hooikaas, Peter Jan, Stapleford, Kenneth A, Moratorio, Gonzalo, Vignuzzi, Marco

Volltext

Chikungunya Virus Overcomes Polyamine Depletion by Mutation of nsP1 and the Opal Stop Codon To Confer Enhanced Replication and Fitness von Mounce, Bryan C, Cesaro, Teresa, Vlajnić, Lea, Vidiņa, Anna, Vallet, Thomas, Weger-Lucarelli, James, Passoni, Gabriella, Stapleford, Kenneth A, Levraud, Jean-Pierre, Vignuzzi, Marco

Volltext

ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53 von Ghouzzi, Vincent El, Bianchi, Federico T, Molineris, Ivan, Mounce, Bryan C, Berto, Gaia E, Rak, Malgorzata, Lebon, Sophie, Aubry, Laetitia, Tocco, Chiara, Gai, Marta, Chiotto, Alessandra MA, Sgrò, Francesco, Pallavicini, Gianmarco, Simon-Loriere, Etienne, Passemard, Sandrine, Vignuzzi, Marco, Gressens, Pierre, Di Cunto, Ferdinando

Volltext

Curcumin inhibits Zika and chikungunya virus infection by inhibiting cell binding von Mounce, Bryan C., Cesaro, Teresa, Carrau, Lucia, Vallet, Thomas, Vignuzzi, Marco

Volltext

Interferon regulatory factor 1 restricts gammaherpesvirus replication in primary immune cells von Mboko, Wadzanai P, Mounce, Bryan C, Emmer, Joseph, Darrah, Eric, Patel, Shailendra B, Tarakanova, Vera L

Volltext

Coxsackievirus B3 Responds to Polyamine Depletion via Enhancement of 2A and 3C Protease Activity von Dial, Courtney N, Tate, Patrick M, Kicmal, Thomas M, Mounce, Bryan C

Volltext

Uptake and metabolism of arginine impact Plasmodium development in the liver von Meireles, Patrícia, Mendes, António M., Aroeira, Rita I., Mounce, Bryan C., Vignuzzi, Marco, Staines, Henry M., Prudêncio, Miguel

Volltext

Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes von Passoni, Gabriella, Langevin, Christelle, Palha, Nuno, Mounce, Bryan C, Briolat, Valérie, Affaticati, Pierre, De Job, Elodie, Joly, Jean-Stéphane, Vignuzzi, Marco, Saleh, Maria-Carla, Herbomel, Philippe, Boudinot, Pierre, Levraud, Jean-Pierre

Volltext

Persistent Coxsackievirus B3 Infection in Pancreatic Ductal Cells In Vitro Downregulates Cellular Polyamine Metabolism von Mastrodomenico, Vincent, LoMascolo, Natalie J, Firpo, Mason R, Villanueva Guzman, Maria Del Mar, Zaporowski, Adam, Mounce, Bryan C

Volltext

Polyamines and Their Role in Virus Infection von Mounce, Bryan C, Olsen, Michelle E, Vignuzzi, Marco, Connor, John H

Volltext

Primary Macrophages Rely on Histone Deacetylase 1 and 2 Expression To Induce Type I Interferon in Response to Gammaherpesvirus Infection von Mounce, Bryan C, Mboko, Wadzanai P, Kanack, Adam J, Tarakanova, Vera L

Volltext

A non-canonical sensing pathway mediates Plasmodium adaptation to amino acid deficiency von Marreiros, Inês M., Marques, Sofia, Parreira, Ana, Mastrodomenico, Vincent, Mounce, Bryan C., Harris, Chantal T., Kafsack, Björn F., Billker, Oliver, Zuzarte-Luís, Vanessa, Mota, Maria M.

Volltext

Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 von Drayman, Nir, DeMarco, Jennifer K., Jones, Krysten A., Azizi, Saara-Anne, Froggatt, Heather M., Tan, Kemin, Maltseva, Natalia Ivanovna, Chen, Siquan, Nicolaescu, Vlad, Dvorkin, Steve, Furlong, Kevin, Kathayat, Rahul S., Firpo, Mason R., Mastrodomenico, Vincent, Bruce, Emily A., Schmidt, Madaline M., Jedrzejczak, Robert, Munoz-Alia, Miguel A., Schuster, Brooke, Nair, Vishnu, Han, Kyu-yeon, O'Brien, Amornrat, Tomatsidou, Anastasia, Meyer, Bjoern, Vignuzzi, Marco, Missiakas, Dominique, Botten, Jason W., Brooke, Christopher B., Lee, Hyun, Baker, Susan C., Mounce, Bryan C., Heaton, Nicholas S., Severson, William E., Palmer, Kenneth E., Dickinson, Bryan C., Joachimiak, Andrzej, Randall, Glenn, Tay, Savas

Volltext