Discovery, Structure–Activity Relationship, and Biological Evaluation of Noninhibitory Small Molecule Chaperones of Glucocerebrosidase von Patnaik, Samarjit, Zheng, Wei, Choi, Jae H, Motabar, Omid, Southall, Noel, Westbroek, Wendy, Lea, Wendy A, Velayati, Arash, Goldin, Ehud, Sidransky, Ellen, Leister, William, Marugan, Juan J

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Disease models for the development of therapies for lysosomal storage diseases von Xu, Miao, Motabar, Omid, Ferrer, Marc, Marugan, Juan J., Zheng, Wei, Ottinger, Elizabeth A.

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Synergistic drug combination effectively blocks Ebola virus infection von Sun, Wei, He, Shihua, Martínez-Romero, Carles, Kouznetsova, Jennifer, Tawa, Gregory, Xu, Miao, Shinn, Paul, Fisher, Ethan G., Long, Yan, Motabar, Omid, Yang, Shu, Sanderson, Philip E., Williamson, Peter R., García-Sastre, Adolfo, Qiu, Xiangguo, Zheng, Wei

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High throughput screening for small molecule therapy for Gaucher disease using patient tissue as the source of mutant glucocerebrosidase von Goldin, Ehud, Zheng, Wei, Motabar, Omid, Southall, Noel, Choi, Jae Hyuk, Marugan, Juan, Austin, Christopher P, Sidransky, Ellen

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Synergistic drug combination effectively blocks Ebola virus infection (P2.321) von Motabar, Omid

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A high throughput glucocerebrosidase assay using the natural substrate glucosylceramide von Motabar, Omid, Goldin, Ehud, Leister, William, Liu, Ke, Southall, Noel, Huang, Wenwei, Marugan, Juan J., Sidransky, Ellen, Zheng, Wei

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Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease von Vu, Mylinh, Li, Rong, Baskfield, Amanda, Lu, Billy, Farkhondeh, Atena, Gorshkov, Kirill, Motabar, Omid, Beers, Jeanette, Chen, Guokai, Zou, Jizhong, Espejo-Mojica, Angela J, Rodríguez-López, Alexander, Alméciga-Díaz, Carlos J, Barrera, Luis A, Jiang, Xuntian, Ory, Daniel S, Marugan, Juan J, Zheng, Wei

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Evaluation of Quinazoline Analogues as Glucocerebrosidase Inhibitors with Chaperone Activity von Marugan, Juan J, Zheng, Wei, Motabar, Omid, Southall, Noel, Goldin, Ehud, Westbroek, Wendy, Stubblefield, Barbara K, Sidransky, Ellen, Aungst, Ronald A, Lea, Wendy A, Simeonov, Anton, Leister, William, Austin, Christopher P

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Discovery of a Novel Noniminosugar Acid α Glucosidase Chaperone Series von Xiao, Jingbo, Westbroek, Wendy, Motabar, Omid, Lea, Wendy A, Hu, Xin, Velayati, Arash, Zheng, Wei, Southall, Noel, Gustafson, Ann Marie, Goldin, Ehud, Sidransky, Ellen, Liu, Ke, Simeonov, Anton, Tamargo, Rafael J, Ribes, Antonia, Matalonga, Leslie, Ferrer, Marc, Marugan, Juan J

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Discovery, SAR, and Biological evaluation of Non-Inhibitory Small Molecule Chaperones of Glucocerebrosidase von Patnaik, Samarjit, Zheng, Wei, Choi, Jae H., Motabar, Omid, Southall, Noel, Westbroek, Wendy, Lea, Wendy A., Velayati, Arash, Goldin, Ehud, Sidransky, Ellen, Leister, William, Marugan, Juan J.

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A new resorufin-based α-glucosidase assay for high-throughput screening von Motabar, Omid, Shi, Zhen-Dan, Goldin, Ehud, Liu, Ke, Southall, Noel, Sidransky, Ellen, Austin, Christopher P., Griffiths, Gary L., Zheng, Wei

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Discovery of a novel non-iminosugar acid alpha glucosidase chaperone series von Xiao, Jingbo, Westbroek, Wendy, Motabar, Omid, Lea, Wendy A., Hu, Xin, Velayati, Arash, Zheng, Wei, Southall, Noel, Gustafson, Ann Marie, Goldin, Ehud, Sidransky, Ellen, Liu, Ke, Simeonov, Anton, Tamargo, Rafael J., Ribes, Antonia, Matalonga, Leslie, Ferrer, Marc, Marugan, Juan J.

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The use of saposin C and phosphatidylserine in functional studies of glucocerebrosidase von Choi, Jae, Motabar, Omid, Zheng, Wei, Marugan, Juan, Sidransky, Ellen, Goldin, Ehud

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Evaluation of 2-thioxo-2,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidin-4(1H)-one analogues as GAA activators von Marugan, Juan J., Zheng, Wei, Motabar, Omid, Southall, Noel, Goldin, Ehud, Sidransky, Ellen, Aungst, Ronald A., Liu, Ke, Sadhukhan, Subir Kumar, Austin, Christopher P.

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Non-iminosugar glucocerebrosidase small molecule chaperones von Marugan, Juan Jose, Huang, Wenwei, Motabar, Omid, Zheng, Wei, Xiao, Jingbo, Patnaik, Samarjit, Southall, Noel, Westbroek, Wendy, Lea, Wendy A, Simeonov, Anton, Goldin, Ehud, Debernardi, Maria A, Sidransky, Ellen

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12. Analysis of enzyme activities of different lysosomal enzymes in brain samples from subjects with Parkinson disease von Hermoni, Yotam Blech, Goldin, Ehud, Motabar, Omid, Sidransky, Ellen

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Synthesis and characterization of a new fluorogenic substrate for alpha-galactosidase von Shi, Zhen-Dan, Motabar, Omid, Goldin, Ehud, Liu, Ke, Southall, Noel, Sidransky, Ellen, Austin, Christopher P, Griffiths, Gary L, Zheng, Wei

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155. High Throughput screen for identifying small molecule modulators of alpha-glucosidase for the potential treatment of Pompe disease von Zheng, Wei, Motabar, Omid, Liu, Ke, Goldin, Ehud, Southall, Noel, Marugan, Juan, Austin, Christopher, Sidransky, Ellen

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Non-iminosugar glucocerebrosidase small molecule chaperonesElectronic supplementary information (ESI) available. See DOI: 10.1039/c1md00200g von Marugan, Juan Jose, Huang, Wenwei, Motabar, Omid, Zheng, Wei, Xiao, Jingbo, Patnaik, Samarjit, Southall, Noel, Westbroek, Wendy, Lea, Wendy A, Simeonov, Anton, Goldin, Ehud, DeBernardi, Maria A, Sidransky, Ellen

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Fabry disease - current treatment and new drug development von Motabar, Omid, Sidransky, Ellen, Goldin, Ehud, Zheng, Wei

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