Matrix metalloproteinase proteomics: substrates, targets, and therapy von Morrison, Charlotte J, Butler, Georgina S, Rodríguez, David, Overall, Christopher M

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Degradomic and yeast 2-hybrid inactive catalytic domain substrate trapping identifies new membrane-type 1 matrix metalloproteinase (MMP14) substrates: CCN3 (Nov) and CCN5 (WISP2) von Butler, Georgina S., Connor, Andrea R., Sounni, Nor Eddine, Eckhard, Ulrich, Morrison, Charlotte J., Noël, Agnès, Overall, Christopher M.

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Membrane Protease Proteomics: Isotope-Coded Affinity Tag MS Identification of Undescribed MT1-Matrix Metalloproteinase Substrates von Tam, Eric M., Morrison, Charlotte J., Wu, Yi I., Stack, M. Sharon, Overall, Christopher M., Gross, Jerome

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Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics von Rodríguez, David, Morrison, Charlotte J., Overall, Christopher M.

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TIMP Independence of Matrix Metalloproteinase (MMP)-2 Activation by Membrane Type 2 (MT2)-MMP Is Determined by Contributions of Both the MT2-MMP Catalytic and Hemopexin C Domains von Morrison, Charlotte J., Overall, Christopher M.

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Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptid... von Eckhard, Ulrich, Huesgen, Pitter F., Schilling, Oliver, Bellac, Caroline L., Butler, Georgina S., Cox, Jennifer H., Dufour, Antoine, Goebeler, Verena, Kappelhoff, Reinhild, Keller, Ulrich auf dem, Klein, Theo, Lange, Philipp F., Marino, Giada, Morrison, Charlotte J., Prudova, Anna, Rodriguez, David, Starr, Amanda E., Wang, Yili, Overall, Christopher M.

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Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14 von Eckhard, Ulrich, Huesgen, Pitter F., Schilling, Oliver, Bellac, Caroline L., Butler, Georgina S., Cox, Jennifer H., Dufour, Antoine, Goebeler, Verena, Kappelhoff, Reinhild, auf dem Keller, Ulrich, Klein, Theo, Lange, Philipp F., Marino, Giada, Morrison, Charlotte J., Prudova, Anna, Rodriguez, David, Starr, Amanda E., Wang, Yili, Overall, Christopher M.

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Membrane-type Matrix Metalloproteinase-3 Regulates Neuronal Responsiveness to Myelin through Nogo-66 Receptor 1 Cleavage von Ferraro, Gino B., Morrison, Charlotte J., Overall, Christopher M., Strittmatter, Stephen M., Fournier, Alyson E.

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Epigenetics: A New Model for Intracellular Parasite–Host Cell Regulation von Robert McMaster, W, Morrison, Charlotte J, Kobor, Michael S

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Stromal regulation of vessel stability by MMP14 and TGFβ von Sounni, Nor E., Dehne, Kerstin, van Kempen, Leon, Egeblad, Mikala, Affara, Nesrine I., Cuevas, Ileana, Wiesen, Jane, Junankar, Simon, Korets, Lidiya, Lee, Jake, Shen, Jennifer, Morrison, Charlotte J., Overall, Christopher M., Krane, Stephen M., Werb, Zena, Boudreau, Nancy, Coussens, Lisa M.

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The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases von Nour, Nadia, Mayer, Gaétan, Mort, John S, Salvas, Alexandre, Mbikay, Majambu, Morrison, Charlotte J, Overall, Christopher M, Seidah, Nabil G

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Cellular Activation of MMP-2 (Gelatinase A) by MT2-MMP Occurs via a TIMP-2-independent Pathway von Morrison, Charlotte J., Butler, Georgina S., Bigg, Heather F., Roberts, Clive R., Soloway, Paul D., Overall, Christopher M.

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Identification of Cellular MMP Substrates Using Quantitative Proteomics: Isotope-Coded Affinity Tags (ICAT) and Isobaric Tags for Relative and Absolute Quantification (iTRAQ) von Butler, Georgina S., Dean, Richard A., Morrison, Charlotte J., Overall, Christopher M.

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Protease degradomics: mass spectrometry discovery of protease substrates and the CLIP-CHIP, a dedicated DNA microarray of all human proteases and inhibitors von Overall, C.M., Tam, E.M., Kappelhoff, R., Connor, A., Ewart, T., Morrison, C.J., Puente, X., López-Otín, C., Seth, A.

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Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase von BIGG, Heather F, MORRISON, Charlotte J, BUTLER, Georgina S, BOGOYEVITCH, Marie A, ZHIPING WANG, SOLOWAY, Paul D, OVERALL, Christopher M

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Utilization of a novel recombinant myoglobin fusion protein expression system to characterize the tissue inhibitor of metalloproteinase (TIMP)-4 and TIMP-2 C-terminal domain and ta... von Kai, Heidi S-T, Butler, Georgina S, Morrison, Charlotte J, King, Angela E, Pelman, Gayle R, Overall, Christopher M

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Humanization of a mouse monoclonal antibody by CDR–grafting: the importance of framework residues on loop conformation von Kettleborough, Catherine A., Saldanha, José, Heath, Victoria J., Morrison, Charlotte J., Bendig, Mary M.

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Utilization of a Novel Recombinant Myoglobin Fusion Protein Expression System to Characterize the Tissue Inhibitor of Metalloproteinase (TIMP)-4 and TIMP-2 C-terminal Domain and Ta... von Kai, Heidi S.-T., Butler, Georgina S., Morrison, Charlotte J., King, Angela E., Pelman, Gayle R., Overall, Christopher M.

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Modification of a recombinant GPI-anchored metalloproteinase for secretion alters the protein glycosylation von Morrison, Charlotte J., Easton, Richard L., Morris, Howard R., McMaster, W. Robert, Piret, James M., Dell, Anne

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Differential stability of proteolytically active and inactive recombinant metalloproteinase in Chinese hamster ovary cells von Morrison, Charlotte J., McMaster, W. Robert, Piret, James M.

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