Enolase inhibitors as therapeutic leads for Naegleria fowleri infection von Milanes, Jillian E, Yan, Victoria C, Pham, Cong-Dat, Muller, Florian, Kwain, Samuel, Rees, Kerrick C, Dominy, Brian N, Whitehead, Daniel C, Millward, Steven W, Bolejack, Madison, Shek, Roger, Tillery, Logan, Phan, Isabelle Q, Staker, Bart, Moseman, E Ashley, Zhang, Xiang, Ma, Xipeng, Jebet, Audriy, Yin, Xinmin, Morris, James C

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A multiplexed high throughput screening assay using flow cytometry identifies glycolytic molecular probes in bloodstream form Trypanosoma brucei von Call, Daniel H., Adjei, John Asafo, Pilgrim, Ryan, Jeong, James W., Willis, E. Vance, Zegarra, Ronald A., Tapia, Nicholas L., Osterhaus, Madalyn, Vance, Jacob A., Voyton, Charles M., Call, James A., Pizarro, Sabrina S., Morris, James C., Christensen, Kenneth A.

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The transcriptome of Balamuthia mandrillaris trophozoites for structure-guided drug design von Phan, Isabelle Q., Rice, Christopher A., Craig, Justin, Noorai, Rooksana E., McDonald, Jacquelyn R., Subramanian, Sandhya, Tillery, Logan, Barrett, Lynn K., Shankar, Vijay, Morris, James C., Van Voorhis, Wesley C., Kyle, Dennis E., Myler, Peter J.

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Environmentally Regulated Glycosome Protein Composition in the African Trypanosome von Bauer, Sarah, Morris, James C, Morris, Meredith T

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A FRET flow cytometry method for monitoring cytosolic and glycosomal glucose in living kinetoplastid parasites von Voyton, Charles M, Qiu, Yijian, Morris, Meredith T, Ackroyd, P Christine, Suryadi, Jimmy, Crowe, Logan, Morris, James C, Christensen, Kenneth A

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Plasmodium vivax and human hexokinases share similar active sites but display distinct quaternary architectures von Srivastava, Shanti Swaroop, Darling, Joseph E, Suryadi, Jimmy, Morris, James C, Drew, Mark E, Subramaniam, Sriram

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Interrogating a Hexokinase-Selected Small-Molecule Library for Inhibitors of Plasmodium falciparum Hexokinase von HARRIS, Michael T, WALKER, Dawn M, DREW, Mark E, MITCHELL, William G, KEVIN DAO, SCHROEDER, Chad E, FLAHERTY, Daniel P, WEINER, Warren S, GOLDEN, Jennifer E, MORRIS, James C

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Enolase Inhibitors as Early Lead Therapeutics against Trypanosoma brucei von Roster, Colm P., LaVigne, Danielle, Milanes, Jillian E., Knight, Emily, Anderson, Heidi D., Pizarro, Sabrina, Harding, Elijah M., Morris, Meredith T., Yan, Victoria C., Pham, Cong-Dat, Muller, Florian, Kwain, Samuel, Rees, Kerrick C., Dominy, Brian, Whitehead, Daniel C., Uddin, Md Nasir, Millward, Steven W., Morris, James C.

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Glucose Signaling Is Important for Nutrient Adaptation during Differentiation of Pleomorphic African Trypanosomes von Qiu, Yijian, Milanes, Jillian E, Jones, Jessica A, Noorai, Rooksana E, Shankar, Vijay, Morris, James C

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A target-based high throughput screen yields Trypanosoma brucei hexokinase small molecule inhibitors with antiparasitic activity von Sharlow, Elizabeth R, Lyda, Todd A, Dodson, Heidi C, Mustata, Gabriela, Morris, Meredith T, Leimgruber, Stephanie S, Lee, Kuo-Hsiung, Kashiwada, Yoshiki, Close, David, Lazo, John S, Morris, James C

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Assembly of Heterohexameric Trypanosome Hexokinases Reveals That Hexokinase 2 Is a Regulable Enzyme von Chambers, Jeremy W., Kearns, Margaret T., Morris, Meredith T., Morris, James C.

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Mannich‐Type Condensation and Domino Quinazolinone‐Amidine Rearrangement Affords Ring‐Fused Mackinazolinones with Anti‐Amoebic Activity von Lish, Matthew S., Milanes, Jillian E., Sanders, Kyana M., Guzei, Ilia A., Morris, James C., Golden, Jennifer E.

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Pharmacophore Establishment and Optimization of Saturated 1,6-Naphthyridine-Fused Quinazolinones that Inhibit Meningoencephalitis-Causing Naegleria fowleri von Lish, Matthew S., McKeon, Jillian E. M., Palmentiero, Caroline M., Pomeroy, Julia M., Roster, Colm P., Guzei, Ilia A., Morris, James C., Golden, Jennifer E.

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Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba von Tillery, Logan, Barrett, Kayleigh, Goldstein, Jenna, Lassner, Jared W, Osterhout, Bram, Tran, Nathan L, Xu, Lily, Young, Ryan M, Craig, Justin, Chun, Ian, Dranow, David M, Abendroth, Jan, Delker, Silvia L, Davies, Douglas R, Mayclin, Stephen J, Calhoun, Brandy, Bolejack, Madison J, Staker, Bart, Subramanian, Sandhya, Phan, Isabelle, Lorimer, Donald D, Myler, Peter J, Edwards, Thomas E, Kyle, Dennis E, Rice, Christopher A, Morris, James C, Leahy, James W, Manetsch, Roman, Barrett, Lynn K, Smith, Craig L, Van Voorhis, Wesley C

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Enzymatic and Structural Characterization of the Naegleria fowleri Glucokinase von Milanes, Jillian E, Suryadi, Jimmy, Abendroth, Jan, Van Voorhis, Wesley C, Barrett, Kayleigh F, Dranow, David M, Phan, Isabelle Q, Patrick, Stephen L, Rozema, Soren D, Khalifa, Muhammad M, Golden, Jennifer E, Morris, James C

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Characterization of Glucokinases from Pathogenic Free-Living Amoebae von Milanes, Jillian E, Suryadi, Jimmy, Monaghan, Neil P, Harding, Elijah M, Morris, Corbin S, Rozema, Soren D, Khalifa, Muhammad M, Golden, Jennifer E, Phan, Isabelle Q, Zigweid, Rachael, Abendroth, Jan, Rice, Christopher A, McCord, Hayden T, Wilson, Stevin, Fenwick, Michael K, Morris, James C

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Synthesis and Evaluation of Benzylamine Inhibitors of Neuropathogenic Naegleria fowleri “Brain-Eating” Amoeba von Pomeroy, Julia M., Khalifa, Muhammad M., Milanes, Jillian E., Palmentiero, Caroline M., Morris, James C., Golden, Jennifer E.

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Exploring the mode of action of ebselen in Trypanosoma brucei hexokinase inhibition von Joice, April C., Harris, Michael T., Kahney, Elizabeth W., Dodson, Heidi C., Maselli, Andrew G., Whitehead, Daniel C., Morris, James C.

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A Microfluidic-Based Microscopy Platform for Continuous Interrogation of Trypanosoma brucei during Environmental Perturbation von Voyton, Charles M, Choi, Jongsu, Qiu, Yijian, Morris, Meredith T, Ackroyd, P. Christine, Morris, James C, Christensen, Kenneth A

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Measuring Dynamic Glycosomal pH Changes in Living Trypanosoma brucei von Call, Daniel, Pizarro, Sabrina S, Tovey, Erica, Knight, Emily, Baumgardner, Carrie, Christensen, Kenneth A, Morris, James C

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