BacPROTACs mediate targeted protein degradation in bacteria von Morreale, Francesca E., Kleine, Stefan, Leodolter, Julia, Junker, Sabryna, Hoi, David M., Ovchinnikov, Stepan, Okun, Anastasia, Kley, Juliane, Kurzbauer, Robert, Junk, Lukas, Guha, Somraj, Podlesainski, David, Kazmaier, Uli, Boehmelt, Guido, Weinstabl, Harald, Rumpel, Klaus, Schmiedel, Volker M., Hartl, Markus, Haselbach, David, Meinhart, Anton, Kaiser, Markus, Clausen, Tim

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Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements von Morreale, Francesca E, Testa, Andrea, Chaugule, Viduth K, Bortoluzzi, Alessio, Ciulli, Alessio, Walden, Helen

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Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening von Morreale, Francesca E, Bortoluzzi, Alessio, Chaugule, Viduth K, Arkinson, Connor, Walden, Helen, Ciulli, Alessio

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Types of Ubiquitin Ligases von Morreale, Francesca Ester, Walden, Helen

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Tagging for degradation — bacteria do it too von Morreale, Francesca Ester

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Inhibitory Control on a Stop Signal Task in Tourette Syndrome before and after Deep Brain Stimulation of the Internal Segment of the Globus Pallidus von Morreale, Francesca, Kefalopoulou, Zinovia, Zrinzo, Ludvic, Limousin, Patricia, Joyce, Eileen, Foltynie, Tom, Jahanshahi, Marjan

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Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria von Junk, Lukas, Schmiedel, Volker M., Guha, Somraj, Fischel, Katharina, Greb, Peter, Vill, Kristin, Krisilia, Violetta, van Geelen, Lasse, Rumpel, Klaus, Kaur, Parvinder, Krishnamurthy, Ramya V., Narayanan, Shridhar, Shandil, Radha Krishan, Singh, Mayas, Kofink, Christiane, Mantoulidis, Andreas, Biber, Philipp, Gmaschitz, Gerhard, Kazmaier, Uli, Meinhart, Anton, Leodolter, Julia, Hoi, David, Junker, Sabryna, Morreale, Francesca Ester, Clausen, Tim, Kalscheuer, Rainer, Weinstabl, Harald, Boehmelt, Guido

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Insight into the Fundamental Interactions between LEDGF Binding Site Inhibitors and Integrase Combining Docking and Molecular Dynamics Simulations von De Luca, Laura, Morreale, Francesca, Chimirri, Alba

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Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival von Hoi, David M., Junker, Sabryna, Junk, Lukas, Schwechel, Kristin, Fischel, Katharina, Podlesainski, David, Hawkins, Paige M.E., van Geelen, Lasse, Kaschani, Farnusch, Leodolter, Julia, Morreale, Francesca Ester, Kleine, Stefan, Guha, Somraj, Rumpel, Klaus, Schmiedel, Volker M., Weinstabl, Harald, Meinhart, Anton, Payne, Richard J., Kaiser, Markus, Hartl, Markus, Boehmelt, Guido, Kazmaier, Uli, Kalscheuer, Rainer, Clausen, Tim

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Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments von Tintori, Cristina, Esposito, Francesca, Morreale, Francesca, Martini, Riccardo, Tramontano, Enzo, Botta, Maurizio

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New scaffolds of natural origin as Integrase–LEDGF/p75 interaction inhibitors: Virtual screening and activity assays von De Luca, Laura, Morreale, Francesca, Christ, Frauke, Debyser, Zeger, Ferro, Stefania, Gitto, Rosaria

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Design and synthesis of N1-aryl-benzimidazoles 2-substituted as novel HIV-1 non-nucleoside reverse transcriptase inhibitors von Monforte, Anna-Maria, Ferro, Stefania, De Luca, Laura, Lo Surdo, Giuseppa, Morreale, Francesca, Pannecouque, Christophe, Balzarini, Jan, Chimirri, Alba

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A new potential approach to block HIV-1 replication via protein–protein interaction and strand-transfer inhibition von Ferro, Stefania, De Luca, Laura, Lo Surdo, Giuseppa, Morreale, Francesca, Christ, Frauke, Debyser, Zeger, Gitto, Rosaria, Chimirri, Alba

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4-[1-(4-Fluorobenzyl)-4-hydroxy-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoic acid as a prototype to develop dual inhibitors of HIV-1 integration process von De Luca, Laura, Gitto, Rosaria, Christ, Frauke, Ferro, Stefania, De Grazia, Sara, Morreale, Francesca, Debyser, Zeger, Chimirri, Alba

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Fragment hopping approach directed at design of HIV IN-LEDGF/p75 interaction inhibitors von De Luca, Laura, Ferro, Stefania, Morreale, Francesca, Christ, Frauke, Debyser, Zeger, Chimirri, Alba, Gitto, Rosaria

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Synthesis and biological evaluation of novel antiviral agents as protein-protein interaction inhibitors von Ferro, Stefania, De Luca, Laura, Morreale, Francesca, Christ, Frauke, Debyser, Zeger, Gitto, Rosaria, Chimirri, Alba

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New scaffolds of natural origin as Integrase LEDGF/p75 interaction inhibitors: Virtual screening and activity assays von De Luca, Laura, Morreale, Francesca, Christ, Frauke, Debyser, Zeger, Ferro, Stefania, Gitto, Rosaria

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Inhibitors of the Interactions between HIV-1 IN and the Cofactor LEDGF/p75 von De Luca, Laura, Ferro, Stefania, Morreale, Francesca, De Grazia, Sara, Chimirri, Alba

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Design and synthesis of N1-aryl-benzimidazoles 2-substituted as novel HIV-1 non-nucleoside reverse transcriptase inhibitors von Monforte, Anna-Maria, Ferro, Stefania, De Luca, Laura, Lo Surdo, Giuseppa, Morreale, Francesca, Pannecouque, Christophe, Balzarini, Jan, Chimirri, Alba

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A new potential approach to block HIV-1 replication via protein-protein interaction and strand-transfer inhibition von Ferro, Stefania, De Luca, Laura, Lo Surdo, Giuseppa, Morreale, Francesca, Christ, Frauke, Debyser, Zeger, Gitto, Rosaria, Chimirri, Alba

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