Characterization of CD4+CD25+ Regulatory T Cells in Patients Treated With High-Dose Interleukin-2 for Metastatic Melanoma or Renal Cell Carcinoma von CESANA, Giovanni C, DERAFFELE, Gail, COHEN, Seth, MOROZIEWICZ, Dorota, MITCHAM, Josephine, STOUTENBURG, John, CHEUNG, Ken, HESDORFFER, Charles, KIM-SCHULZE, Seunghee, KAUFMAN, Howard L

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Isogenic human trophectoderm cells demonstrate the role of NDUFA4 and associated variants in ZIKV infection von Yang, Liuliu, Han, Yuling, Zhou, Ting, Lacko, Lauretta A., Saeed, Mohsan, Tan, Christina, Danziger, Ron, Zhu, Jiajun, Zhao, Zeping, Cahir, Clare, Giani, Alice Maria, Li, Yang, Dong, Xue, Moroziewicz, Dorota, Paull, Daniel, Chen, Zhengming, Zhong, Aaron, Noggle, Scott A., Rice, Charles M., Qi, Qibin, Evans, Todd, Chen, Shuibing

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P238 von Kim-Schulze, S, Moroziewicz, D, Wainstein, A, Elliott, B, Kaufman, H.L

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Reevaluation of Neuronal Ceroid Lipofuscinoses: Atypical Juvenile Onset May Be the Result of CLN2 Mutations von Wisniewski, K.E., Kaczmarski, A., Kida, E., Connell, F., Kaczmarski, W., Michalewski, M.P., Moroziewicz, D.N., Zhong, N.

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Identification of novel CLN2 mutations shows Canadian specific NCL2 alleles von Ju, W, Zhong, R, Moore, S, Moroziewicz, D, Currie, J R, Parfrey, P, Brown, W T, Zhong, N

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Targeting the local tumor microenvironment with vaccinia virus expressing B7.1 for the treatment of melanoma von Kaufman, Howard L, Deraffele, Gail, Mitcham, Josephine, Moroziewicz, Dorota, Cohen, Seth M, Hurst-Wicker, Karl S, Cheung, Ken, Lee, David S, Divito, Joseph, Voulo, Magalese, Donovan, Julie, Dolan, Kate, Manson, Kelledy, Panicali, Dennis, Wang, Ena, Hörig, Heidi, Marincola, Francesco M

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The lymphoid chemokine CCL21 costimulates naïve T cell expansion and Th1 polarization of non-regulatory CD4 + T cells von Flanagan, Kenneth, Moroziewicz, Dorota, Kwak, Heesun, Hörig, Heidi, Kaufman, Howard L.

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Two common mutations in the CLN2 gene underlie late infantile neuronal ceroid lipofuscinosis von NAN ZHONG, WISNIEWSKI, K. E, HARTIKAINEN, J, WEINA JU, MOROZIEWICZ, D. N, MCLENDON, L, BROOKS, S. S, BROWN, W. T

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Heterogeneity of late-infantile neuronal ceroid lipofuscinosis von Zhong, N, Moroziewicz, D N, Ju, W, Jurkiewicz, A, Johnston, L, Wisniewski, K E, Brown, W T

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CLN-encoded proteins do not interact with each other von ZHONG, Nanbert A, MOROZIEWICZ, Dorota N, WEINA JU, WISNIEWSKI, Krystyna E, JURKIEWICZ, Anna, BROWN, W. Ted

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New mutations in the neuronal ceroid lipofuscinosis genes von Mole, S E, Zhong, N A, Sarpong, A, Logan, W P, Hofmann, S, Yi, W, Franken, P F, van Diggelen, O P, Breuning, M H, Moroziewicz, D, Ju, W, Salonen, T, Holmberg, V, Järvelä, I, Taschner, P E

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Late Infantile Neuronal Ceroid Lipofuscinosis Is Due to Splicing Mutations in the CLN2 Gene von Hartikainen, Jaana M., Ju, Weina, Wisniewski, Krystyna E., Moroziewicz, Dorota N., Kaczmarski, Alexandra L., McLendon, Lucille, Zhong, David, Suarez, Carolin T., Brown, W.Ted, Zhong, Nan

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Correlation of effector and regulatory T cell responses with clinical outcome in metastatic renal cell carcinoma patients treated with MVA-5T4 vaccine and high-dose interleukin-2 von Kaufman, H. L., Kim-Schulze, S., Kim, D., Moroziewicz, D., DeRaffele, G., Mitcham, J., Shingler, W. H., Harrop, R., Naylor, S.

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A phase I clinical trial of MVA expressing 5T4 and high-dose interleukin-2 (IL-2) for metastatic renal cell carcinoma von Kaufman, H. L., Deraffele, G., Mitcham, J., Moroziewicz, D., Kim-Schulze, S., Petrulio, C. A., Harrop, R., Naylor, S.

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P238: Mucosal vaccination prevents spontaneous colorectal carcinoma and induces long-term immunity in mice von Kim-Schulze, S., Moroziewicz, D., Wainstein, A., Elliott, B., Kaufman, H.L.

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Manipulating the local tumor microenvironment with vaccinia virus expressing costimulatory molecules for the treatment of melanoma von Hesdorffer, C. S., Hoerig, H., Deraffele, G., Mitcham, J., Moroziewicz, D., Hurst-Wicker, K., Di Vito, J., Vuolo, M., Schuetz, T., Kaufman, H. L.

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Manipulating the local tumor microenvironment with vaccinia virus expressing costimulatory molecules for the treatment of melanoma von Hesdorffer, C. S., Hoerig, H., Deraffele, G., Mitcham, J., Moroziewicz, D., Hurst-Wicker, K., Di Vito, J., Vuolo, M., Schuetz, T., Kaufman, H. L.

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Molecular diagnosis of and carrier screening for the neuronal ceroid lipofuscinoses von Zhong, N A, Wisniewski, K E, Ju, W, Moroziewicz, D N, Jurkiewicz, A, McLendon, L, Jenkins, E C, Brown, W T

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Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression von Seah, Carina, Breen, Michael S., Rusielewicz, Tom, Bader, Heather N., Xu, Changxin, Hunter, Christopher J., McCarthy, Barry, Deans, P. J. Michael, Chattopadhyay, Mitali, Goldberg, Jordan, Dobariya, Saunil, Desarnaud, Frank, Makotkine, Iouri, Flory, Janine D., Bierer, Linda M., Staniskyte, Migle, Noggle, Scott A., Huckins, Laura M., Paull, Daniel, Brennand, Kristen J., Yehuda, Rachel

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Reactive Astrocytes Derived From Human Induced Pluripotent Stem Cells Suppress Oligodendrocyte Precursor Cell Differentiation von Smith, Matthew D, Chamling, Xitiz, Gill, Alexander J, Martinez, Hector, Li, Weifeng, Fitzgerald, Kathryn C, Sotirchos, Elias S, Moroziewicz, Dorota, Bauer, Lauren, Paull, Daniel, Gharagozloo, Marjan, Bhargava, Pavan, Zack, Donald J, Fossati, Valentina, Calabresi, Peter A

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