Enteroviral infections in the pathogenesis of type 1 diabetes: new insights for therapeutic intervention von Richardson, Sarah J, Morgan, Noel G

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Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease von Flanagan, Sarah E, Haapaniemi, Emma, Russell, Mark A, Caswell, Richard, Allen, Hana Lango, De Franco, Elisa, McDonald, Timothy J, Rajala, Hanna, Ramelius, Anita, Barton, John, Heiskanen, Kaarina, Heiskanen-Kosma, Tarja, Kajosaari, Merja, Murphy, Nuala P, Milenkovic, Tatjana, Seppänen, Mikko, Lernmark, Åke, Mustjoki, Satu, Otonkoski, Timo, Kere, Juha, Morgan, Noel G, Ellard, Sian, Hattersley, Andrew T

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An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells von Colli, Maikel L., Ramos-Rodríguez, Mireia, Nakayasu, Ernesto S., Alvelos, Maria I., Lopes, Miguel, Hill, Jessica L. E., Turatsinze, Jean-Valery, Coomans de Brachène, Alexandra, Russell, Mark A., Raurell-Vila, Helena, Castela, Angela, Juan-Mateu, Jonàs, Webb-Robertson, Bobbie-Jo M., Krogvold, Lars, Dahl-Jorgensen, Knut, Marselli, Lorella, Marchetti, Piero, Richardson, Sarah J., Morgan, Noel G., Metz, Thomas O., Pasquali, Lorenzo, Eizirik, Décio L.

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C-Peptide Decline in Type 1 Diabetes Has Two Phases: An Initial Exponential Fall and a Subsequent Stable Phase von Shields, Beverley M, McDonald, Timothy J, Oram, Richard, Hill, Anita, Hudson, Michelle, Leete, Pia, Pearson, Ewan R, Richardson, Sarah J, Morgan, Noel G, Hattersley, Andrew T

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Footprints of Immune Cells in the Pancreas in Type 1 Diabetes; to "B" or Not to "B": Is That Still the Question? von Leete, Pia, Morgan, Noel G.

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GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans von Stone, Virginia M., Dhayal, Shalinee, Brocklehurst, Katy J., Lenaghan, Carol, Sörhede Winzell, Maria, Hammar, Mårten, Xu, Xiufeng, Smith, David M., Morgan, Noel G.

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Abnormal islet sphingolipid metabolism in type 1 diabetes von Holm, Laurits J., Krogvold, Lars, Hasselby, Jane P., Kaur, Simranjeet, Claessens, Laura A., Russell, Mark A., Mathews, Clayton E., Hanssen, Kristian F., Morgan, Noel G., Koeleman, Bobby P. C., Roep, Bart O., Gerling, Ivan C., Pociot, Flemming, Dahl-Jørgensen, Knut, Buschard, Karsten

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The role of the interferon/JAK-STAT axis in driving islet HLA-I hyperexpression in type 1 diabetes von Russell, Mark A, Richardson, Sarah J, Morgan, Noel G

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An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation von Saarimäki-Vire, Jonna, Balboa, Diego, Russell, Mark A., Saarikettu, Juha, Kinnunen, Matias, Keskitalo, Salla, Malhi, Amrinder, Valensisi, Cristina, Andrus, Colin, Eurola, Solja, Grym, Heli, Ustinov, Jarkko, Wartiovaara, Kirmo, Hawkins, R. David, Silvennoinen, Olli, Varjosalo, Markku, Morgan, Noel G., Otonkoski, Timo

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Developmentally dynamic changes in DNA methylation in the human pancreas von MacCalman, Ailsa, De Franco, Elisa, Franklin, Alice, Flaxman, Christine S, Richardson, Sarah J, Murrall, Kathryn, Burrage, Joe, Walker, Emma M, Morgan, Noel G, Hattersley, Andrew T, Dempster, Emma L, Hannon, Eilis, Jeffries, Aaron R, Owens, Nick D L, Mill, Jonathan

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The beneficial effects of n-3 polyunsaturated fatty acids on diet induced obesity and impaired glucose control do not require Gpr120 von Bjursell, Mikael, Xu, Xiufeng, Admyre, Therése, Böttcher, Gerhard, Lundin, Sofia, Nilsson, Ralf, Stone, Virginia M, Morgan, Noel G, Lam, Yan Y, Storlien, Leonard H, Lindén, Daniel, Smith, David M, Bohlooly-Y, Mohammad, Oscarsson, Jan

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Pancreatic Pathology in Type 1 Diabetes Mellitus von Richardson, Sarah J., Morgan, Noel G., Foulis, Alan K.

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Long-chain saturated fatty acid species are not toxic to human pancreatic beta-cells and may offer protection against pro-inflammatory cytokine induced beta-cell death von Thomas, Patricia, Leslie, Kaiyven A., Welters, Hannah J., Morgan, Noel G.

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Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion von Viloria, Katrina, Nasteska, Daniela, Briant, Linford J.B., Heising, Silke, Larner, Dean P., Fine, Nicholas H.F., Ashford, Fiona B., da Silva Xavier, Gabriela, Ramos, Maria Jiménez, Hasib, Annie, Cuozzo, Federica, Manning Fox, Jocelyn E., MacDonald, Patrick E., Akerman, Ildem, Lavery, Gareth G., Flaxman, Christine, Morgan, Noel G., Richardson, Sarah J., Hewison, Martin, Hodson, David J.

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Differential regulation of the endoplasmic reticulum stress response in pancreatic β-cells exposed to long-chain saturated and monounsaturated fatty acids von Diakogiannaki, Eleftheria, Welters, Hannah J, Morgan, Noel G

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Investigation of the utility of the 1.1B4 cell as a model human beta cell line for study of persistent enteroviral infection von Chaffey, Jessica R., Young, Jay, Leslie, Kaiyven A., Partridge, Katie, Akhbari, Pouria, Dhayal, Shalinee, Hill, Jessica L., Wedgwood, Kyle C. A., Burnett, Edward, Russell, Mark A., Richardson, Sarah J., Morgan, Noel G.

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Type 1 Diabetes: Interferons and the Aftermath of Pancreatic Beta-Cell Enteroviral Infection von Akhbari, Pouria, Richardson, Sarah J., Morgan, Noel G.

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Offspring of Mice Exposed to a Low-Protein Diet in Utero Demonstrate Changes in mTOR Signaling in Pancreatic Islets of Langerhans, Associated with Altered Glucagon and Insulin Expr... von King, Renee, Hill, Jessica L, Saha, Bibek, Tong, Yuzhen, Strutt, Brenda J, Russell, Mark A, Morgan, Noel G, Richardson, Sarah J, Hill, David J

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Detection of Antiviral Tissue Responses and Increased Cell Stress in the Pancreatic Islets of Newly Diagnosed Type 1 Diabetes Patients: Results From the DiViD Study von Krogvold, Lars, Leete, Pia, Mynarek, Ida M, Russell, Mark A, Gerling, Ivan C, Lenchik, Nataliya I, Mathews, Clayton, Richardson, Sarah J, Morgan, Noel G, Dahl-Jørgensen, Knut

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Heterogeneity and endotypes in type 1 diabetes mellitus von Redondo, Maria J., Morgan, Noel G.

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