RNA therapeutics inactivate PCSK9 by inducing a unique intracellular retention form von Rocha, Cristina S.J, Wiklander, Oscar P.B, Larsson, Lilian, Moreno, Pedro M.D, Parini, Paolo, Lundin, Karin E, Smith, C.I. Edvard

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CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression von Zaghloul, Eman M, Gissberg, Olof, Moreno, Pedro M D, Siggens, Lee, Hällbrink, Mattias, Jørgensen, Anna S, Ekwall, Karl, Zain, Rula, Wengel, Jesper, Lundin, Karin E, Smith, C I Edvard

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Delivery of Antisense Oligonucleotides Mediated by a Hydrogel System: In Vitro and In Vivo Application in the Context of Spinal Cord Injury von Moreno, Pedro M. D., Rodrigues, Teresa, Torrado, Marília, Amaral, Isabel F., Pêgo, Ana P.

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Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model von Bestas, Burcu, Moreno, Pedro M D, Blomberg, K Emelie M, Mohammad, Dara K, Saleh, Amer F, Sutlu, Tolga, Nordin, Joel Z, Guterstam, Peter, Gustafsson, Manuela O, Kharazi, Shabnam, Piątosa, Barbara, Roberts, Thomas C, Behlke, Mark A, Wood, Matthew J A, Gait, Michael J, Lundin, Karin E, El Andaloussi, Samir, Månsson, Robert, Berglöf, Anna, Wengel, Jesper, Smith, C I Edvard

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A high-throughput bioimaging study to assess the impact of chitosan-based nanoparticle degradation on DNA delivery performance von Gomes, Carla P., Varela-Moreira, Aida, Leiro, Victoria, Lopes, Cátia D.F., Moreno, Pedro M.D., Gomez-Lazaro, Maria, Pêgo, Ana P.

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Hydrogel-Assisted Antisense LNA Gapmer Delivery for In Situ Gene Silencing in Spinal Cord Injury von Moreno, Pedro M.D., Ferreira, Ana R., Salvador, Daniela, Rodrigues, Maria T., Torrado, Marília, Carvalho, Eva D., Tedebark, Ulf, Sousa, Mónica M., Amaral, Isabel F., Wengel, Jesper, Pêgo, Ana P.

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Optimizing anti-gene oligonucleotide 'Zorro-LNA' for improved strand invasion into duplex DNA von Zaghloul, Eman M, Madsen, Andreas S, Moreno, Pedro M.D, Oprea, Iulian I, El-Andaloussi, Samir, Bestas, Burcu, Gupta, Pankaj, Pedersen, Erik B, Lundin, Karin E, Wengel, Jesper, Smith, C.I. Edvard

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synthetic snRNA m₃G-CAP enhances nuclear delivery of exogenous proteins and nucleic acids von Moreno, Pedro M.D, Wenska, Malgorzata, Lundin, Karin E, Wrange, Örjan, Strömberg, Roger, Smith, C.I. Edvard

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Enhancing Neuronal Cell Uptake of Therapeutic Nucleic Acids with Tetrahedral DNA Nanostructures von Martins, Ana S. G., Reis, Sara D., Benson, Erik, Domingues, Marco M., Cortinhas, João, Vidal Silva, Joana A., Santos, Sofia D., Santos, Nuno C., Pêgo, Ana P., Moreno, Pedro M. D.

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Engineering a Novel Self-Assembled Multi-siRNA Nanocaged Architecture with Controlled Enzyme-Mediated siRNA Release von Moreno, Pedro M. D., Cortinhas, João, Martins, Ana S., Pêgo, Ana P.

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PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation von Ezzat, Kariem, EL Andaloussi, Samir, Zaghloul, Eman M., Lehto, Taavi, Lindberg, Staffan, Moreno, Pedro M. D., Viola, Joana R., Magdy, Tarek, Abdo, Rania, Guterstam, Peter, Sillard, Rannar, Hammond, Suzan M., Wood, Matthew J. A., Arzumanov, Andrey A., Gait, Michael J., Smith, C. I. Edvard, Hällbrink, Mattias, Langel, Ülo

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Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo von Andaloussi, Samir E L, Lehto, Taavi, Mäger, Imre, Rosenthal-Aizman, Katri, Oprea, Iulian I, Simonson, Oscar E, Sork, Helena, Ezzat, Kariem, Copolovici, Dana M, Kurrikoff, Kaido, Viola, Joana R, Zaghloul, Eman M, Sillard, Rannar, Johansson, Henrik J, Said Hassane, Fatouma, Guterstam, Peter, Suhorutšenko, Julia, Moreno, Pedro M D, Oskolkov, Nikita, Hälldin, Jonas, Tedebark, Ulf, Metspalu, Andres, Lebleu, Bernard, Lehtiö, Janne, Smith, C I Edvard, Langel, Ulo

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Therapeutic antisense oligonucleotides against cancer: hurdling to the clinic von Moreno, Pedro M D, Pêgo, Ana P

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A Peptide-based Vector for Efficient Gene Transfer In Vitro and In Vivo von Lehto, Taavi, Simonson, Oscar E, Mäger, Imre, Ezzat, Kariem, Sork, Helena, Copolovici, Dana-Maria, Viola, Joana R, Zaghloul, Eman M, Lundin, Per, Moreno, Pedro MD, Mäe, Maarja, Oskolkov, Nikita, Suhorutšenko, Julia, Smith, CI Edvard, Andaloussi, Samir EL

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Nuclease resistant oligonucleotides with cell penetrating properties von Milton, Stefan, Honcharenko, Dmytro, Rocha, Cristina S J, Moreno, Pedro M D, Smith, C I Edvard, Strömberg, Roger

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Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes von Geny, Sylvain, Moreno, Pedro M D, Krzywkowski, Tomasz, Gissberg, Olof, Andersen, Nicolai K, Isse, Abdirisaq J, El-Madani, Amro M, Lou, Chenguang, Pabon, Y Vladimir, Anderson, Brooke A, Zaghloul, Eman M, Zain, Rula, Hrdlicka, Patrick J, Jørgensen, Per T, Nilsson, Mats, Lundin, Karin E, Pedersen, Erik B, Wengel, Jesper, Smith, C I Edvard

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Functionalized chitosan derivatives as nonviral vectors: physicochemical properties of acylated N,N,N-trimethyl chitosan/oligonucleotide nanopolyplexes von Santos, Joyce C C, Moreno, Pedro M D, Mansur, Alexandra A P, Leiro, Victoria, Mansur, Herman S, Pêgo, Ana Paula

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Biodegradable PEG-dendritic block copolymers: synthesis and biofunctionality assessment as vectors of siRNA von Leiro, Victoria, Garcia, João Pedro, Moreno, Pedro M D, Spencer, Ana Patrícia, Fernandez-Villamarin, Marcos, Riguera, Ricardo, Fernandez-Megia, Eduardo, Paula Pêgo, Ana

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Delivery of Splice Switching Oligonucleotides by Amphiphilic Chitosan-Based Nanoparticles von Moreno, Pedro M. D, Santos, Joyce C, Gomes, Carla P, Varela-Moreira, Aida, Costa, Artur, Leiro, Victoria, Mansur, Herman, Pêgo, Ana P

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Antisense Oligonucleotides Modulating Activation of a Nonsense-Mediated RNA Decay Switch Exon in the ATM Gene von Kralovicova, Jana, Moreno, Pedro M.D., Cross, Nicholas C.P., Pêgo, Ana Paula, Vorechovsky, Igor

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