PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation von Ezzat, Kariem, EL Andaloussi, Samir, Zaghloul, Eman M., Lehto, Taavi, Lindberg, Staffan, Moreno, Pedro M. D., Viola, Joana R., Magdy, Tarek, Abdo, Rania, Guterstam, Peter, Sillard, Rannar, Hammond, Suzan M., Wood, Matthew J. A., Arzumanov, Andrey A., Gait, Michael J., Smith, C. I. Edvard, Hällbrink, Mattias, Langel, Ülo

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Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo von Andaloussi, Samir E L, Lehto, Taavi, Mäger, Imre, Rosenthal-Aizman, Katri, Oprea, Iulian I, Simonson, Oscar E, Sork, Helena, Ezzat, Kariem, Copolovici, Dana M, Kurrikoff, Kaido, Viola, Joana R, Zaghloul, Eman M, Sillard, Rannar, Johansson, Henrik J, Said Hassane, Fatouma, Guterstam, Peter, Suhorutšenko, Julia, Moreno, Pedro M D, Oskolkov, Nikita, Hälldin, Jonas, Tedebark, Ulf, Metspalu, Andres, Lebleu, Bernard, Lehtiö, Janne, Smith, C I Edvard, Langel, Ulo

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CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression von Zaghloul, Eman M, Gissberg, Olof, Moreno, Pedro M D, Siggens, Lee, Hällbrink, Mattias, Jørgensen, Anna S, Ekwall, Karl, Zain, Rula, Wengel, Jesper, Lundin, Karin E, Smith, C I Edvard

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A Peptide-based Vector for Efficient Gene Transfer In Vitro and In Vivo von Lehto, Taavi, Simonson, Oscar E, Mäger, Imre, Ezzat, Kariem, Sork, Helena, Copolovici, Dana-Maria, Viola, Joana R, Zaghloul, Eman M, Lundin, Per, Moreno, Pedro MD, Mäe, Maarja, Oskolkov, Nikita, Suhorutšenko, Julia, Smith, CI Edvard, Andaloussi, Samir EL

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Nuclease resistant oligonucleotides with cell penetrating properties von Milton, Stefan, Honcharenko, Dmytro, Rocha, Cristina S J, Moreno, Pedro M D, Smith, C I Edvard, Strömberg, Roger

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Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model von Bestas, Burcu, Moreno, Pedro M D, Blomberg, K Emelie M, Mohammad, Dara K, Saleh, Amer F, Sutlu, Tolga, Nordin, Joel Z, Guterstam, Peter, Gustafsson, Manuela O, Kharazi, Shabnam, Piątosa, Barbara, Roberts, Thomas C, Behlke, Mark A, Wood, Matthew J A, Gait, Michael J, Lundin, Karin E, El Andaloussi, Samir, Månsson, Robert, Berglöf, Anna, Wengel, Jesper, Smith, C I Edvard

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Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes von Geny, Sylvain, Moreno, Pedro M D, Krzywkowski, Tomasz, Gissberg, Olof, Andersen, Nicolai K, Isse, Abdirisaq J, El-Madani, Amro M, Lou, Chenguang, Pabon, Y Vladimir, Anderson, Brooke A, Zaghloul, Eman M, Zain, Rula, Hrdlicka, Patrick J, Jørgensen, Per T, Nilsson, Mats, Lundin, Karin E, Pedersen, Erik B, Wengel, Jesper, Smith, C I Edvard

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RNA therapeutics inactivate PCSK9 by inducing a unique intracellular retention form von Rocha, Cristina S.J, Wiklander, Oscar P.B, Larsson, Lilian, Moreno, Pedro M.D, Parini, Paolo, Lundin, Karin E, Smith, C.I. Edvard

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Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA von Moreno, Pedro M D, Geny, Sylvain, Pabon, Y Vladimir, Bergquist, Helen, Zaghloul, Eman M, Rocha, Cristina S J, Oprea, Iulian I, Bestas, Burcu, Andaloussi, Samir El, Jørgensen, Per T, Pedersen, Erik B, Lundin, Karin E, Zain, Rula, Wengel, Jesper, Smith, C I Edvard

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Optimizing anti-gene oligonucleotide 'Zorro-LNA' for improved strand invasion into duplex DNA von Zaghloul, Eman M, Madsen, Andreas S, Moreno, Pedro M.D, Oprea, Iulian I, El-Andaloussi, Samir, Bestas, Burcu, Gupta, Pankaj, Pedersen, Erik B, Lundin, Karin E, Wengel, Jesper, Smith, C.I. Edvard

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synthetic snRNA m₃G-CAP enhances nuclear delivery of exogenous proteins and nucleic acids von Moreno, Pedro M.D, Wenska, Malgorzata, Lundin, Karin E, Wrange, Örjan, Strömberg, Roger, Smith, C.I. Edvard

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Synthetic m 3 G-CAP attachment necessitates a minimum trinucleotide constituent to be recognised as a nuclear import signal von Honcharenko, M., Bestas, B., Jezowska, M., Wojtczak, B. A., Moreno, P. M. D., Romanowska, J., Bächle, S. M., Darzynkiewicz, E., Jemielity, J., Smith, C. I. E., Strömberg, R.

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Design and Application of Bispecific Splice-Switching Oligonucleotides von Bestas, Burcu, McClorey, Graham, Tedebark, Ulf, Moreno, Pedro M.D., Roberts, Thomas C., Hammond, Suzan M., Smith, C.I. Edvard, Wood, Matthew J.A., Andaloussi, Samir EL

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Fatty acid–spermine conjugates as DNA carriers for nonviral in vivo gene delivery von Viola, J R, Leijonmarck, H, Simonson, O E, Oprea, I I, Frithiof, R, Purhonen, P, Moreno, P M D, Lundin, K E, Strömberg, R, Smith, C I E

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A synthetic snRNA m 3 G-CAP enhances nuclear delivery of exogenous proteins and nucleic acids von Moreno, PMD, Wenska, M, Lundin, KE, Wrange, O, Stromberg, R, Smith, CIE

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Nanotechnology approaches for gene transfer von Lundin, Karin E, Simonson, Oscar E, Moreno, Pedro M. D, Zaghloul, Eman M, Oprea, Iulian I, Svahn, Mathias G, Smith, C. I. Edvard

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Synthetic m sub(3)G-CAP attachment necessitates a minimum trinucleotide constituent to be recognised as a nuclear import signal von Honcharenko, M, Bestas, B, Jezowska, M, Wojtczak, BA, Moreno, PMD, Romanowska, J, Baechle, S M, Darzynkiewicz, E, Jemielity, J, Smith, CIE, Stromberg, R

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Repeatable, Inducible Micro-RNA-Based Technology Tightly Controls Liver Transgene Expression von Oprea, Iulian I, Viola, Joana R, Moreno, Pedro M D, Simonson, Oscar E, Rodin, Sergey, Teller, Nathalie, Tryggvason, Karl, Lundin, Karin E, Girnita, Leonard, Smith, Carl Inge Edvard

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Splice-Correction of X-Linked Agammaglobulinemia in a Human BAC-Transgenic Mouse Model Using Oligonucleotides von Bestas, B, Moreno, PMD, Blomberg, EKM, Mohammad, DK, Lundin, KE, Mansson, R, Berglof, A, Wengel, J, Smith, ECI

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Temperature-Assisted Cyclic Hybridization (TACH): An Improved Method for Supercoiled DNA Hybridization von Oprea, Iulian I, Simonson, Oscar E, Moreno, Pedro M. D, Viola, Joana R, Lundin, Karin E, Smith, C. I. Edvard

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