Wild-Type KRAS Allele Effects on Druggable Targets in KRAS Mutant Lung Adenocarcinomas von Baldelli, Elisa, El Gazzah, Emna, Moran, John Conor, Hodge, Kimberley A, Manojlovic, Zarko, Bassiouni, Rania, Carpten, John D, Ludovini, Vienna, Baglivo, Sara, Crinò, Lucio, Bianconi, Fortunato, Dong, Ting, Loffredo, Jeremy, Petricoin, Emanuel F, Pierobon, Mariaelena

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Protein network mapping of retinoblastomas for the identification of therapeutic targets von Baldelli, Elisa, Moran, John Conor, Masalu, Nestory, Hassan, Said, Rambau, Peter Fabian, Kahima, Jackson, Ludovini, Vienna, Pistola, Lorenza, Tofanetti, Francesca Romana, Siggillino, Annamaria, Petricoin, Emanuel, Pierobon, Mariaelena, Crino, Lucio

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The benefits and limitations of animal models for translational research in cartilage repair von Moran, Conor J., Ramesh, Ashwanth, Brama, Pieter A. J., O’Byrne, John M., O’Brien, Fergal J., Levingstone, Tanya J.

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Monogenic causes of chronic kidney disease in adults von Connaughton, Dervla M., Kennedy, Claire, Shril, Shirlee, Mann, Nina, Murray, Susan L., Williams, Patrick A., Conlon, Eoin, Nakayama, Makiko, van der Ven, Amelie T., Ityel, Hadas, Kause, Franziska, Kolvenbach, Caroline M., Dai, Rufeng, Vivante, Asaf, Braun, Daniela A., Schneider, Ronen, Kitzler, Thomas M., Moloney, Brona, Moran, Conor P., Smyth, John S., Kennedy, Alan, Benson, Katherine, Stapleton, Caragh, Denton, Mark, Magee, Colm, O’Seaghdha, Conall M., Plant, William D., Griffin, Matthew D., Awan, Atif, Sweeney, Clodagh, Mane, Shrikant M., Lifton, Richard P., Griffin, Brenda, Leavey, Sean, Casserly, Liam, de Freitas, Declan G., Holian, John, Dorman, Anthony, Doyle, Brendan, Lavin, Peter J., Little, Mark A., Conlon, Peter J., Hildebrandt, Friedhelm

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Adverse Biology in Adenocarcinoma of the Esophagus and Esophagogastric Junction Impacts Survival and Response to Neoadjuvant Therapy Independent of Anatomic Subtype von Donlon, Noel E., Elliott, Jessie A., Donohoe, Claire L., Murphy, Conor F., Nugent, Tim, Moran, Brendan, King, Sinead, Ravi, Narayanasamy, Reynolds, John V.

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The Clinical Application of Urine Soluble CD163 in ANCA-Associated Vasculitis von Moran, Sarah M, Scott, Jennifer, Clarkson, Michael R, Conlon, Niall, Dunne, Jean, Griffin, Matthew D, Griffin, Tomas P, Groarke, Elizabeth, Holian, John, Judge, Conor, Wyse, Jason, McLoughlin, Kirsty, O'Hara, Paul V, Kretzler, Matthias, Little, Mark A

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A pilot feasibility study comparing large language models in extracting key information from ICU patient text records from an Irish population von Urquhart, Emma, Ryan, John, Hartigan, Sean, Nita, Ciprian, Hanley, Ciara, Moran, Peter, Bates, John, Jooste, Rachel, Judge, Conor, Laffey, John G., Madden, Michael G., McNicholas, Bairbre A.

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Evaluation of a co-culture of rapidly isolated chondrocytes and stem cells seeded on tri-layered collagen-based scaffolds in a caprine osteochondral defect model von Levingstone, Tanya J., Sheehy, Eamon J., Moran, Conor J., Cunniffe, Gráinne M., Diaz Payno, Pedro J., Brady, Robert T., Almeida, Henrique V., Carroll, Simon F., O’Byrne, John M., Kelly, Daniel J., Brama, Pieter AJ, O’ Brien, Fergal J.

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A Pilot Study of Gut-Brain Signaling After Octreotide Therapy for Unintentional Weight Loss After Esophagectomy von Murphy, Conor F, Stratford, Nicholas, Docherty, Neil G, Moran, Brendan, Elliott, Jessie A, Healy, Marie-Louise, McMorrow, Jason P, Ravi, Narayanasamy, Goldstone, Anthony P, Reynolds, John V, le Roux, Carel W

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Consensus statement on the multidisciplinary management of patients with recurrent and primary rectal cancer beyond total mesorectal excision planes von Ali, S. Mohammed, Antoniou, Anthony, Beynon, John, Bhangu, Aneel, Bose, Pradeep, Boyle, Kirsten, Branagan, Graham, Brown, Gina, Burling, David, Chang, George J., Clark, Susan K., Colquhoun, Patrick, Crane, Christopher H., Darzi, Ara, Das, Prajnan, de Wilt, Johannes H. W., Delaney, Conor P., Desai, Anant, Davies, Mark, Dietz, David, Dozois, Eric J., Duff, Michael, Dziki, Adam, Fitzgerald, J. Edward, Frizelle, Frank A., George, Bruce, George, Mark L., Georgiou, Panagiotis, Glynne‐Jones, Rob, Goldin, Robert D., Gupta, Arun, Harji, Deena, Harris, Dean A., Hawkins, Maria, Heriot, Alexander G., Holm, Torbjörn, Hompes, Roel, Jeys, Lee, Jenkins, John T., Kiran, Ravi P., Koh, Cherry E., Laurberg, Soren, Law, Wai L., Liberman, A. Sender, Marshall, Michele, McArthur, David R., Mirnezami, Alex H., Moran, Brendan, Mortenson, Neil, Myers, Eddie, Nicholls, R. John, O'Connell, P. Ronan, O'Dwyer, Sarah T., Oliver, Alex, Pallan, Arvind, Patel, Prashant, Patel, Uday B., Radley, Simon, Ramsey, Kelvin W. D., Rasmussen, Peter C., Richard, Carole, Rutten, Harm J. T., Sagar, Peter, Sebag‐Montefiore, David, Solomon, Michael J., Stocchi, Luca, Swallow, Carol J., Tait, Diana, Tan, Emile, Tekkis, Paris P., van As, Nicholas, Vuong, Te, Wiggers, Theo, Wilson, Malcolm, Winter, Desmond, Woodhouse, Christopher

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4553 REAL WORLD DATA-DRIVEN IDENTIFICATION OF ANCA VASCULITIS RELAPSE von Scott, Jennifer, White, Arthur, Walsh, Cathal, Aslett, Louis, Rutherford, Matthew, Ng, James, Judge, Conor, Sebastian, Kuruvilla, Kelleher, John, Power, Julie, Conlon, Niall, Moran, Sarah, Luqmani, Raashid, Merkel, Peter, Tesar, Vladimir, Hruskova, Zdenka, Little, Mark

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Computable phenotype for real-world, data-driven retrospective identification of relapse in ANCA-associated vasculitis von Scott, Jennifer, White, Arthur, Walsh, Cathal, Aslett, Louis, Rutherford, Matthew A, Ng, James, Judge, Conor, Sebastian, Kuruvilla, O’Brien, Sorcha, Kelleher, John, Power, Julie, Conlon, Niall, Moran, Sarah M, Luqmani, Raashid Ahmed, Merkel, Peter A, Tesar, Vladimir, Hruskova, Zdenka, Little, Mark A

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IBD BioResource: an open-access platform of 25 000 patients to accelerate research in Crohn’s and Colitis von Parkes, Miles, Abdelmalek, Ehab, Appleby, Richard, Baburajan, Bijay, Baker-moffat, Michelle, Banim, Paul, Barbour, Jamie, Bloom, Stuart, Bose, Monica, Brookes, Matthew, Butterworth, Jeff, Anderson, Carl, Carter, Martyn, Chatzinikolaou, Stamatia, Clark, Katie, Cole, Andrew, Dallal, Helen Jane, Davies, Albert, Decaestecker, John, Dhar, Anjan, Edwards, Cathryn, Elamin, Khalid, Foley, Stephen, Gavin, Daniel, Gordon, John, Grellier, Leonie, Gunasekera, Anton, Hamill, Grace, Hancock, Laura, Hanna, Mina, Hart, Ailsa, Irving, Peter, Javaid, Babur, Johnson, Matthew, Keld, Richard, Kennedy, Nick, Kok, Klaartje Bel, Lahiff, Conor, Landy, Jonathan, Lees, Charlie, Lewis, Stephen, Li, Andi, Limdi, Jimmy, Lindsay, James, Lobo, Alan, Macdonald, Chris, Macfaul, George, Mansfield, John, Mclaughlin, Simon, Mclaughlin, John, Muddu, Ajay, Nair, Sunny, Nwokolo, Chuka, O’donohoe, Lynn, Oglesby, Arabis, Oza, Chirag, Panter, Simon, Parkes, Gareth, Patani, Timi, Patel, Vinod, Penn, Ruth, Phillips, Anne, Phillis, Kath, Pollock, Richard, Preston, Cathryn, Rahman, Monira, Ramakrishnan, Subramaniam, Rees, Colin, Roberts, Phil, Samuel, Sunil, Sebastian, Shaji, Selinger, Christian, Shenderey, Richard, Shenoy, Achuth, Shmueli, Udi, Simmons, Alison, Singh, Salil, Sinha, Leena, Smith, Katherine, Smith, Paul, Smith, Melissa, Sprakes, Michael, Subramanian, Sreedhar, Theron, Byron, Tindall, Theresa, Tremelling, Mark, Vani, Deven, Verma, Ajay, Wilkins, Joy, Woods, Annette, Simpkins, Rachel, Thorbinson, Catherine, Francis, Deepthy, Shawky, Rasha, Pele, Laetitia, Satsangi, Jack, Jostins, Luke, Lamb, Christopher, Mathew, Christopher, Lee, James

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Radical surgery versus organ preservation via short-course radiotherapy followed by transanal endoscopic microsurgery for early-stage rectal cancer (TREC): a randomised, open-label... von Bach, Simon P, Gilbert, Alexandra, Korsgen, Stephan, Geh, Ian, Hill, James, Gill, Talvinder, Tutton, Matthew G, Khan, Jim, Robinson, Jonathan, Steward, Mark, Cunningham, Christopher, Beveridge, Alan, Handley, Kelly, Vince, Alex, Hilken, Nick, Sidile, Chakanaka, Wilcockson, Adrian, Peto, Richard, Crosby, Tom, Olliff, Julie, Ashok, Katti, Slawik, Simone, Smethurst, Andrew, Sripadam, Rajaram, Tagore, Veena, Terlizzo, Monica, Nisar, Pasha, Stewart, Alexandra, Trickett, Jonathan, Ashish, Bansal, Billings, Peter, Chandran, Palanichamy, Corr, Conor, Favill, Edward, Gollins, Simon, Marsh, Peter, Rajagopal, Ramesh, Cooper, Rachel, Hatfield, Paul, Lowe, Andy, Ostrowski, Julian, Robinson, Jonathan, Simpson, Rhian, Adams, Richard, Bleehen, Robert, Morgan, Meleri, Boone, Darren, Lacey, Nicola, Stunell, Helen, Wu, Shaobin, Hadaki, Maher, Blunt, Dominic, Cleator, Susan, Darzi, Ara, Goldin, Robert, Dobson, Mike, Pitt, Mark, Susnerwala, Shabbir, Williamson, Deborah, Howarth, Georgina, Horgan, Alan, McDonald, Fiona, Scott, John, Simmons, Timothy, Biswas, Debashis, Hernon, James, Kapur, Sandeep, Sington, James, Speakman, Christopher, Williams, Stuart, Garg, Dharmendra, Gill, Talvinder, Hegab, Mohammed, Hobday, Catherine, Shrimankar, Jyotsna, Jones, Oliver, Mortensen, Neil, Slater, Andrew, Wang, Lai, Warren, Bryan, Weaver, Andrew, Flubacher, Maxine, Tarver, David, Beable, Richard, Cowlishaw, David, Vogiatzis, Prokopios, Saunders, Mark, Teo, Mark, Geh, Ian, Glaholm, John, Goldstein, Mark, Langman, Gerald, Morton, Dion, Falk, Stephen, Thomas, Michael, Haba, Yasser, Harris, Guy, Hookway, Max, Skull, Angela, Umar, Tijani

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Consensus statement on the multidisciplinary management of patients with recurrent and primary rectal cancer beyond total mesorectal excision planes von Ali, S. Mohammed, Antoniou, Anthony, Beynon, John, Bhangu, Aneel, Bose, Pradeep, Boyle, Kirsten, Branagan, Graham, Brown, Gina, Burling, David, Chang, George J., Clark, Susan K., Colquhoun, Patrick, Crane, Christopher H., Darzi, Ara, Das, Prajnan, de Wilt, Johannes H. W., Delaney, Conor P., Desai, Anant, Davies, Mark, Dietz, David, Dozois, Eric J., Duff, Michael, Dziki, Adam, Fitzgerald, J. Edward, Frizelle, Frank A., George, Bruce, George, Mark L., Georgiou, Panagiotis, Glynne‐Jones, Rob, Goldin, Robert D., Gupta, Arun, Harji, Deena, Harris, Dean A., Hawkins, Maria, Heriot, Alexander G., Holm, Torbjörn, Hompes, Roel, Jeys, Lee, Jenkins, John T., Kiran, Ravi P., Koh, Cherry E., Laurberg, Soren, Law, Wai L., Liberman, A. Sender, Marshall, Michele, McArthur, David R., Mirnezami, Alex H., Moran, Brendan, Mortenson, Neil, Myers, Eddie, Nicholls, R. John, O'Connell, P. Ronan, O'Dwyer, Sarah T., Oliver, Alex, Pallan, Arvind, Patel, Prashant, Patel, Uday B., Radley, Simon, Ramsey, Kelvin W. D., Rasmussen, Peter C., Richard, Carole, Rutten, Harm J. T., Sagar, Peter, Sebag‐Montefiore, David, Solomon, Michael J., Stocchi, Luca, Swallow, Carol J., Tait, Diana, Tan, Emile, Tekkis, Paris P., van As, Nicholas, Vuong, Te, Wiggers, Theo, Wilson, Malcolm, Winter, Desmond, Woodhouse, Christopher

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Short-term outcomes in older patients with peritoneal malignancy treated with cytoreductive surgery and HIPEC: Experience with 245 patients from a national centre von Keyes, Alan Martin, Kelly, Michael Eamon, McInerney, Niall, Khan, Mohammad Faraz, Bolger, Jarlath Christopher, McCormack, Emilie, Grundy, Josh, McCormack, Orla, MacHale, John, Conneely, John, Brennan, Donal, Cahill, Ronan, Shields, Conor, Moran, Brendan, Mulsow, Jürgen

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Correlation between PSOGI pathological classification and survival outcomes of patients with pseudomyxoma peritonei treated using cytoreductive surgery and HIPEC: national referral... von Martín-Román, Lorena, Hannan, Enda, Faraz Khan, Mohammad, Müller, Anna Sophia, Shields, Conor, Aird, John, Moran, Brendan, Mulsow, Jurgen

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Tu1790 COMBINATION BIOLOGIC OR SMALL MOLECULE THERAPY IN INFLAMMATORY BOWEL DISEASE von Mcshane, Catherine, Varley, Rachel, Fennessy, Anne, Campion, John R., Hazel, Karl, Ring, Eabha, Marrinan, Alan, Palmer, Conor, Keogh, Aine, Byron, Clodagh, O'Sullivan, Aoife M., Boland, Karen, Buckley, Martin, Dunne, Cara, Farrell, Richard J., Hall, Barry, Hartery, Karen, Kelly, Orlaith, Leyden, Jan, Mckiernan, Susan, Moran, Carthage P., Mulcahy, Hugh, O'Toole, Aoibhlinn, Patchett, Stephen, Sheehan, Donal, Sheridan, Juliette, Slattery, Eoin, Smyth, Claire M., Ghosh, Subrata, Mcnamara, Deirdre, Egan, Laurence, Doherty, Glen, McCarthy, Jane, Kevans, David

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029An Audit of Dementia Care in an Irish University Hospital von Small, Cliona, Moran, Conor, Elsiddig, Mohamed, McAteer, Claire, Killeen, Emily, Beaumont, Cliodhna, Ferguson, Elizabeth, Sheridan, Sheighle, Coimin, Diarmuid O, Connolly, Warren, McCabe, John, Kyne, Lorraine

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Quality-of-life outcomes in older patients with early-stage rectal cancer receiving organ-preserving treatment with hypofractionated short-course radiotherapy followed by transanal... von Gilbert, Alexandra, Homer, Victoria, Korsgen, Stephan, Geh, Ian, Hill, James, Gill, Talvinder, Tutton, Matthew, Khan, Jim, Robinson, Jonathan, Steward, Mark, Cunningham, Christopher, Kaur, Manjinder, Magill, Laura, Sebag-Montefiore, David, Bach, Simon P, Vince, Alex, Hilken, Nick, Sidile, Chakanaka, Wilcockson, Adrian, Peto, Richard, Crosby, Tom, Olliff, Julie, Ashok, Katti, Slawik, Simone, Smethurst, Andrew, Sripadam, Rajaram, Tagore, Veena, Terlizzo, Monica, Nisar, Pasha, Stewart, Alexandra, Trickett, Jonathan, Ashish, Bansal, Billings, Peter, Chandran, Palanichamy, Corr, Conor, Favill, Edward, Gollins, Simon, Marsh, Peter, Rajagopal, Ramesh, Cooper, Rachel, Hatfield, Paul, Lowe, Andy, Ostrowski, Julian, Simpson, Rhian, Adams, Richard, Bleehen, Robert, Morgan, Meleri, Boone, Darren, Lacey, Nicola, Stunell, Helen, Wu, Shaobin, Hadaki, Maher, Blunt, Dominic, Cleator, Susan, Darzi, Ara, Goldin, Robert, Dobson, Mike, Pitt, Mark, Susnerwala, Shabbir, Williamson, Deborah, Howarth, Georgina, Horgan, Alan, McDonald, Fiona, Scott, John, Simmons, Timothy, Biswas, Debashis, Hernon, James, Kapur, Sandeep, Sington, James, Speakman, Christopher, Williams, Stuart, Garg, Dharmendra, Gill, Talvinder, Hegab, Mohammed, Hobday, Catherine, Shrimankar, Jyotsna, Jones, Oliver, Mortensen, Neil, Slater, Andrew, Warren, Bryan, Weaver, Andrew, Flubacher, Maxine, Tarver, David, Beable, Richard, Cowlishaw, David, Vogiatzis, Prokopios, Saunders, Mark, Teo, Mark, Geh, Ian, Glaholm, John, Goldstein, Mark, Langman, Gerald, Morton, Dion, Falk, Stephen, Thomas, Michael, Haba, Yasser, Harris, Guy, Hookway, Max, Skull, Angela, Umar, Tijani

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