Sphingosine-1-phosphate modulates PAR1-mediated human platelet activation in a concentration-dependent biphasic manner von Liu, Haonan, Jackson, Molly L., Goudswaard, Lucy J., Moore, Samantha F., Hutchinson, James L., Hers, Ingeborg

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NADPH Oxidase NOX2 Mediates Rapid Cellular Oxidation following ATP Stimulation of Endotoxin-Primed Macrophages von Moore, Samantha F, MacKenzie, Amanda B

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Opposing Roles of GSK3 alpha and GSK3 beta Phosphorylation in Platelet Function and Thrombosis von Moore, Samantha F., Agbani, Ejaife O., Wersall, Andreas, Poole, Alastair W., Williams, Chris M., Zhao, Xiaojuan, Li, Yong, Hutchinson, James L., Hunter, Roger W., Hers, Ingeborg

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A phenome-wide approach to identify causal risk factors for deep vein thrombosis von Constantinescu, Andrei-Emil, Bull, Caroline J, Goudswaard, Lucy J, Zheng, Jie, Elsworth, Benjamin, Timpson, Nicholas J, Moore, Samantha F, Hers, Ingeborg, Vincent, Emma E

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Phenotype description and response to thrombopoietin receptor agonist in DIAPH1-related disorder von Westbury, Sarah K., Downes, Kate, Burney, Claire, Lozano, Maria L., Obaji, Samya G., Toh, Cheng Hock, Sevivas, Teresa, Morgan, Neil V., Erber, Wendy N., Kempster, Carly, Moore, Samantha F., Thys, Chantal, Papadia, Sofia, Ouwehand, Willem H., Laffan, Michael A., Gomez, Keith, Freson, Kathleen, Rivera, Jose, Mumford, Andrew D.

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In-depth PtdIns(3,4,5)P3 signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function von Durrant, Tom N., Hutchinson, James L., Heesom, Kate J., Anderson, Karen E., Stephens, Len R., Hawkins, Phillip T., Marshall, Aaron J., Moore, Samantha F., Hers, Ingeborg

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Rapamycin restrains platelet procoagulant responses via FKBP-mediated protection of mitochondrial integrity von Śledź, Kamila M., Moore, Samantha F., Durrant, Tom N., Blair, Thomas A., Hunter, Roger W., Hers, Ingeborg

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Redundant role of ASK1-mediated p38MAPK activation in human platelet function von Sledz, Kamila M., Moore, Samantha F., Vijayaragavan, Vijayasameerah, Mallah, Shahida, Goudswaard, Lucy J., Williams, Christopher M., Hunter, Roger W., Hers, Ingeborg

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Phosphoinositide 3-Kinases p110α and p110β Have Differential Roles in Insulin-Like Growth Factor-1–Mediated Akt Phosphorylation and Platelet Priming von Blair, Thomas A, Moore, Samantha F, Williams, Christopher M, Poole, Alastair W, Vanhaesebroeck, Bart, Hers, Ingeborg

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Critical roles for the phosphatidylinositide 3-kinase isoforms p110β and p110γ in thrombopoietin-mediated priming of platelet function von Moore, Samantha F., Smith, Nina R., Blair, Thomas A., Durrant, Tom N., Hers, Ingeborg

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The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin αIIbβ3 Outside-in Signaling von Battram, Anthony M., Durrant, Tom N., Agbani, Ejaife O., Heesom, Kate J., Paul, David S., Piatt, Raymond, Poole, Alastair W., Cullen, Peter J., Bergmeier, Wolfgang, Moore, Samantha F., Hers, Ingeborg

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Identification of PtdIns(3,4)P2 effectors in human platelets using quantitative proteomics von Durrant, Tom N., Moore, Samantha F., Bayliss, Asha L., Jiang, Yiliang, Aitken, Elizabeth W., Wilson, Marieangela C., Heesom, Kate J., Hers, Ingeborg

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Identification of PtdIns(3,4)P-2 effectors in human platelets using quantitative proteomics von Durrant, Tom N., Moore, Samantha F., Bayliss, Asha L., Jiang, Yiliang, Aitken, Elizabeth W., Wilson, Marieangela C., Heesom, Kate J., Hers, Ingeborg

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A key role for redox signaling in rapid P2X7 receptor-induced IL-1 beta processing in human monocytes von Hewinson, James, Moore, Samantha F, Glover, Christian, Watts, Andrew G, MacKenzie, Amanda B

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Loss of the insulin receptor in murine megakaryocytes/platelets causes thrombocytosis and alterations in IGF signalling von Moore, Samantha F, Williams, Christopher M, Brown, Edward, Blair, Thomas A, Harper, Matthew T, Coward, Richard J, Poole, Alastair W, Hers, Ingeborg

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Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis von Agbani, Ejaife O., Williams, Christopher M., Li, Yong, van den Bosch, Marion T.J., Moore, Samantha F., Mauroux, Adele, Hodgson, Lorna, Verkman, Alan S., Hers, Ingeborg, Poole, Alastair W.

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Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function von Trory, Justin S., Munkacsi, Attila, Śledź, Kamila M., Vautrinot, Jordan, Goudswaard, Lucy J., Jackson, Molly L., Heesom, Kate J., Moore, Samantha F., Poole, Alastair W., Nabet, Behnam, Aggarwal, Varinder K., Hers, Ingeborg

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Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis von Agbani, Ejaife O, Williams, Christopher M, Li, Yong, van den Bosch, Marion Tj, Moore, Samantha F, Mauroux, Adele, Hodgson, Lorna, Verkman, Alan S, Hers, Ingeborg, Poole, Alastair W

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In-depth PtdIns(3,4,5)P 3 signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function von Durrant, Tom N, Hutchinson, James L, Heesom, Kate J, Anderson, Karen E, Stephens, Len R, Hawkins, Phillip T, Marshall, Aaron J, Moore, Samantha F, Hers, Ingeborg

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Murine macrophage P2X7 receptors support rapid prothrombotic responses von Moore, Samantha F, MacKenzie, Amanda B

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