Platelet‐type von Willebrand disease: Local disorder of the platelet GPIbα β‐switch drives high‐affinity binding to von Willebrand factor von Tischer, Alexander, Machha, Venkata R., Moon‐Tasson, Laurie, Auton, Matthew

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Glycosylation sterically inhibits platelet adhesion to von Willebrand factor without altering intrinsic conformational dynamics von Tischer, Alexander, Machha, Venkata R., Moon‐Tasson, Laurie, Benson, Linda M., Auton, Matthew

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Reduction in C‐reactive protein indicates successful targeting of the IL‐1/IL‐6 axis resulting in improved survival in early stage multiple myeloma von Lust, John A., Lacy, Martha Q., Zeldenrust, Steven R., Witzig, Thomas E., Moon‐Tasson, Laurie L., Dinarello, Charles A., Donovan, Kathleen A.

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Induction of a Chronic Disease State in Patients With Smoldering or Indolent Multiple Myeloma by Targeting Interleukin 1β-Induced Interleukin 6 Production and the Myeloma Prolifera... von Lust, John A., MD, PhD, Lacy, Martha Q., MD, Zeldenrust, Steven R., MD, PhD, Dispenzieri, Angela, MD, Gertz, Morie A., MD, Witzig, Thomas E., MD, Kumar, Shaji, MD, Hayman, Suzanne R., MD, Russell, Stephen J., MD, PhD, Buadi, Francis K., MD, Geyer, Susan M., PhD, Campbell, Megan E., MS, Kyle, Robert A., MD, Rajkumar, S. Vincent, MD, Greipp, Philip R., MD, Kline, Michael P., PhD, Xiong, Yuning, MD, PhD, Moon-Tasson, Laurie L., BS, Donovan, Kathleen A., PhD

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The epitope of the antibody used in the REAADS VWF activity assay is quaternary von Tischer, Alexander, Moon-Tasson, Laurie, Auton, Matthew

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Quantification of von Willebrand factor and ADAMTS-13 after traumatic injury: a pilot study von MacArthur, Taleen A, Goswami, Julie, Moon Tasson, Laurie, Tischer, Alexander, Bailey, Kent R, Spears, Grant M, Dong, Jing-Fei, Auton, Matthew, Kozar, Rosemary, Park, Myung S

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Data on the purification and crystallization of the loss-of-function von Willebrand disease variant (p.Gly1324Ser) of the von Willebrand factor A1 domain von Campbell, James C., Tischer, Alexander, Machha, Venkata, Moon-Tasson, Laurie, Sankaran, Banumathi, Kim, Choel, Auton, Matthew

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Structure-resolved dynamics of type 2M von Willebrand disease von Tischer, Alexander, Moon-Tasson, Laurie, Auton, Matthew

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Removal of the vicinal disulfide enhances the platelet-capturing function of von Willebrand factor von Tischer, Alexander, Moon-Tasson, Laurie, Auton, Matthew

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Misfolding of vWF to Pathologically Disordered Conformations Impacts the Severity of von Willebrand Disease von Tischer, Alexander, Madde, Pranathi, Moon-Tasson, Laurie, Auton, Matthew

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Microsatellite Instability and 8p Allelic Imbalance in Stage B2 and C Colorectal Cancers von Halling, Kevin C., French, Amy J., McDonnell, Shannon K., Burgart, Lawrence J., Schaid, Daniel J., Peterson, Brett J., Moon-Tasson, Laurie, Mahoney, Michelle R., Sargent, Daniel J., O'Connell, Michael J., Witzig, Thomas E., Farr, Gist H., Goldberg, Richard M., Thibodeau, Stephen N.

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The Von Willebrand Factor A1–Collagen III Interaction Is Independent of Conformation and Type 2 Von Willebrand Disease Phenotype von Machha, Venkata R., Tischer, Alexander, Moon-Tasson, Laurie, Auton, Matthew

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Misfolding Induced By the Mutations V1314D and F1369I Affects the Function and the Structure of the Von Willebrand A1-Domain von Tischer, Alexander, Madde, Pranathi, Moon Tasson, Laurie, Auton, Matthew

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Mutational Constraints on Local Unfolding Inhibit the Rheological Adaptation of von Willebrand Factor von Tischer, Alexander, Campbell, James C., Machha, Venkata R., Moon-Tasson, Laurie, Benson, Linda M., Sankaran, Banumathi, Kim, Choel, Auton, Matthew

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Evidence for the Misfolding of the A1 Domain within Multimeric von Willebrand Factor in Type 2 von Willebrand Disease von Tischer, Alexander, Brehm, Maria A., Machha, Venkata R., Moon-Tasson, Laurie, Benson, Linda M., Nelton, Katelynn J., Leger, Rachel R., Obser, Tobias, Martinez-Vargas, Marina, Whitten, Steven T., Chen, Dong, Pruthi, Rajiv K., Bergen, H. Robert, Cruz, Miguel A., Schneppenheim, Reinhard, Auton, Matthew

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Conformation-specific RNA aptamers for phenotypic distinction between normal von Willebrand factor and type 2B von Willebrand disease von Machha, Venkata R, Tischer, Alexander, Moon-Tasson, Laurie, Tange, Julie, Santiago-Davis, Annyoceli, Pruthi, Rajiv K, Chen, Dong, Maher, 3rd, L James, Auton, Matthew

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A p.Arg127Gln variant in GPIbα LRR5 allosterically enhances affinity for VWF: a novel form of platelet-type VWD von Bury, Loredana, Falcinelli, Emanuela, Kuchi Bhotla, Haripriya, Mezzasoma, Anna Maria, Guglielmini, Giuseppe, Tischer, Alexander, Moon-Tasson, Laurie, Auton, Matthew, Gresele, Paolo

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Interplay Between IL-1, IL-6 and IL-17 in IL-1 Receptor Antagonist (IL-1Ra) Treated Multiple Myeloma Patients von Donovan, Kathleen A., Moon-Tasson, Laurie L., Lust, John A

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Abstract 2449: A novel humanized anti-IL-1beta antibody is highly effective at inhibiting IL-1 induced IL-6 production in myeloma patients in vitro von Lust, John, Moon-Tasson, Laurie, Solinger, Alan, Donovan, Kathleen

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Abstract 2582: P2X7 receptor is functional in myeloma cell lines and myeloma patient cells and can be modulated by P2X7 receptor antagonists: Implications for myeloma therapy von Donovan, Kathleen A., Moon-Tasson, Laurie, Hromockyj, Alexander E., Meyer, Debra M., Lust, John A.

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