PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP von Wang, Huibing, Meng, Huyan, Li, Xingyan, Zhu, Kezhou, Dong, Kangyun, Mookhtiar, Adnan K., Wei, Huiting, Li, Ying, Sun, Shao-Cong, Yuan, Junying

Volltext

PRMT5 Regulates DNA Repair by Controlling the Alternative Splicing of Histone-Modifying Enzymes von Hamard, Pierre-Jacques, Santiago, Gabriel E., Liu, Fan, Karl, Daniel L., Martinez, Concepcion, Man, Na, Mookhtiar, Adnan K., Duffort, Stephanie, Greenblatt, Sarah, Verdun, Ramiro E., Nimer, Stephen D.

Volltext

BRAF and AXL oncogenes drive RIPK3 expression loss in cancer von Najafov, Ayaz, Zervantonakis, Ioannis K, Mookhtiar, Adnan K, Greninger, Patricia, March, Ryan J, Egan, Regina K, Luu, Hoang Son, Stover, Daniel G, Matulonis, Ursula A, Benes, Cyril H, Yuan, Junying

Volltext

RIPK1 Promotes Energy Sensing by the mTORC1 Pathway von Najafov, Ayaz, Luu, Hoang Son, Mookhtiar, Adnan K., Mifflin, Lauren, Xia, Hong-guang, Amin, Palak P., Ordureau, Alban, Wang, Huibing, Yuan, Junying

Volltext

Drug Repositioning in Glioblastoma: A Pathway Perspective von Tan, Sze Kiat, Jermakowicz, Anna, Mookhtiar, Adnan K, Nemeroff, Charles B, Schürer, Stephan C, Ayad, Nagi G

Volltext

The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression von Mas, Gloria, Man, Na, Nakata, Yuichiro, Martinez-Caja, Concepcion, Karl, Daniel, Beckedorff, Felipe, Tamiro, Francesco, Chen, Chuan, Duffort, Stephanie, Itonaga, Hidehiro, Mookhtiar, Adnan K, Kunkalla, Kranthi, Valencia, Alfredo M, Collings, Clayton K, Kadoch, Cigall, Vega, Francisco, Kogan, Scott C, Shiekhattar, Ramin, Morey, Lluis, Bilbao, Daniel, Nimer, Stephen D

Volltext

Tyrosine phosphorylation of CARM1 promotes its enzymatic activity and alters its target specificity von Itonaga, Hidehiro, Mookhtiar, Adnan K., Greenblatt, Sarah M., Liu, Fan, Martinez, Concepcion, Bilbao, Daniel, Rains, Masai, Hamard, Pierre-Jacques, Sun, Jun, Umeano, Afoma C., Duffort, Stephanie, Chen, Chuan, Man, Na, Mas, Gloria, Tottone, Luca, Totiger, Tulasigeri, Bradley, Terrence, Taylor, Justin, Schürer, Stephan, Nimer, Stephen D.

Volltext

Long non‐coding RNA: a versatile regulator of the nuclear factor‐κB signalling circuit von Mao, Xiaohua, Su, Zhenyi, Mookhtiar, Adnan K.

Volltext

Long non-coding RNA: a versatile regulator of the nuclear factor-[kappa]B signalling circuit von Mao, Xiaohua, Su, Zhenyi, Mookhtiar, Adnan K

Volltext

TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL von Najafov, Ayaz, Mookhtiar, Adnan K., Luu, Hoang Son, Ordureau, Alban, Pan, Heling, Amin, Palak P., Li, Ying, Lu, Qingxian, Yuan, Junying

Volltext

ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC von Dziedzic, Slawomir A., Su, Zhenyi, Jean Barrett, Vica, Najafov, Ayaz, Mookhtiar, Adnan K., Amin, Palak, Pan, Heling, Sun, Li, Zhu, Hong, Ma, Averil, Abbott, Derek W., Yuan, Junying

Volltext

PRMT5-mediated histone arginine methylation antagonizes transcriptional repression by polycomb complex PRC2 von Liu, Fan, Xu, Ye, Lu, Xiaoqing, Hamard, Pierre-Jacques, Karl, Daniel L, Man, Na, Mookhtiar, Adnan K, Martinez, Concepcion, Lossos, Izidore S, Sun, Jun, Nimer, Stephen D

Volltext

Arginine Methylation of BRD4 By CARM1 Regulates Its Function in AML von Mookhtiar, Adnan K., Itonaga, Hidehiro, Greenblatt, Sarah, Martinez, Concepcion, Sun, Jun, Hossack, Krystal Lisa, Shiekhattar, Ramin, Bilbao, Daniel, Figueroa, Maria Ken E., Sidoli, Simone, Nimer, Stephen D.

Volltext

CARM1 Inhibition: Evaluation of Response and Efficacy in Acute Myeloid Leukemia von Mookhtiar, Adnan K, Greenblatt, Sarah, Man, Na, Karl, Daniel, Stathias, Vasileios, Schurer, Stephan, Nimer, Stephen D.

Volltext

Tyrosine Phosphorylation of CARM1 Promotes Its Enzymatic Activity and Alters Its Target Specificity in Myeloid Neoplasms with Hyperactivated JAK2 von Itonaga, Hidehiro, Mookhtiar, Adnan K, Greenblatt, Sarah, Liu, Fan, Martinez, Concepcion, Grozovsky, Renata, Bilbao, Daniel, Rains, Masai, Hamard, Pierre-Jacques, Sun, Jun, Umeano, Afoma, Duffort, Stephanie, Chen, Chuan, Man, Na, Mas Martin, Gloria, Schürer, Stephen, Nimer, Stephen D

Volltext

The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression von Mas, Gloria, Man, Na, Nakata, Yuichiro, Martinez-Caja, Concepcion, Karl, Daniel, Beckedorff, Felipe, Tamiro, Francesco, Chen, Chuan, Duffort, Stephanie, Itonaga, Hidehiro, Mookhtiar, Adnan K, Kunkalla, Kranthi, Valencia, Alfredo M, Collings, Clayton K, Kadoch, Cigall, Vega, Francisco, Kogan, Scott C, Morey, Lluis, Bilbao, Daniel, Nimer, Stephen D

Volltext

The Baf Subunit Dpf2 Regulates Resolution of Inflammation By Controlling Macrophage Differentiation Transcription Factor Networks von Mas Martin, Gloria, Man, Na, Karl, Daniel, Martinez, Concepcion, Duffort, Stephanie, Itonaga, Hidehiro, Mookhtiar, Adnan K, Bilbao, Daniel, Kunkalla, Kranthi, Valencia, Alfredo M, Collings, Clayton, Kadoch, Cigall, Vega, Francisco, Kogan, Scott C., Nimer, Stephen

Volltext

PRMT5 regulates DNA repair by controlling the alternative splicing of key histone-modifying enzymes von Hamard, Pierre-Jacques, Santiago, Gabriel E., Liu, Fan, Karl, Daniel L., Martinez, Concepcion, Man, Na, Mookhtiar, Adnan K., Duffort, Stephanie, Greenblatt, Sarah, Verdun, Ramiro E., Nimer, Stephen D.

Volltext