Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset von Harly, Christelle, Guillaume, Yves, Nedellec, Steven, Peigné, Cassie-Marie, Mönkkönen, Hannu, Mönkkönen, Jukka, Li, Jianqiang, Kuball, Jürgen, Adams, Erin J., Netzer, Sonia, Déchanet-Merville, Julie, Léger, Alexandra, Herrmann, Thomas, Breathnach, Richard, Olive, Daniel, Bonneville, Marc, Scotet, Emmanuel

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Zoledronic acid repolarizes tumour‐associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway von Coscia, Marta, Quaglino, Elena, Iezzi, Manuela, Curcio, Claudia, Pantaleoni, Francesca, Riganti, Chiara, Holen, Ingunn, Mönkkönen, Hannu, Boccadoro, Mario, Forni, Guido, Musiani, Piero, Bosia, Amalia, Cavallo, Federica, Massaia, Massimo

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Antitumor Effects of Doxorubicin Followed by Zoledronic Acid in a Mouse Model of Breast Cancer von Ottewell, Penelope D., Mönkkönen, Hannu, Jones, Mark, Lefley, Diane V., Coleman, Robert E., Holen, Ingunn

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Zoledronic acid induces formation of a pro‐apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF‐7 cells in vitro von Räikkönen, Johanna, Crockett, Julie C, Rogers, Michael J, Mönkkönen, Hannu, Auriola, Seppo, Mönkkönen, Jukka

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Zoledronic acid-induced IPP/ApppI production in vivo von Mönkkönen, Hannu, Ottewell, Penelope D., Kuokkanen, Johanna, Mönkkönen, Jukka, Auriola, Seppo, Holen, Ingunn

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Bisphosphonate-induced ATP analog formation and its effect on inhibition of cancer cell growth von Mönkkönen, Hannu, Kuokkanen, Johanna, Holen, Ingunn, Evans, Alyson, Lefley, Diane V, Jauhiainen, Marjo, Auriola, Seppo, Mönkkönen, Jukka

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Correlation between time-dependent inhibition of human farnesyl pyrophosphate synthase and blockade of mevalonate pathway by nitrogen-containing bisphosphonates in cultured cells von Räikkönen, Johanna, Taskinen, Markku, Dunford, James E., Mönkkönen, Hannu, Auriola, Seppo, Mönkkönen, Jukka

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A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen‐containing bisphosphona... von Mönkkönen, Hannu, Auriola, Seppo, Lehenkari, Petri, Kellinsalmi, Maarit, Hassinen, Ilmo E, Vepsäläinen, Jouko, Mönkkönen, Jukka

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Differential Effect of Doxorubicin and Zoledronic Acid on Intraosseous versus Extraosseous Breast Tumor Growth In vivo von Ottewell, Penelope D, Deux, Blandine, Mönkkönen, Hannu, Cross, Simon, Coleman, Robert E, Clezardin, Philippe, Holen, Ingunn

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Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells von Räikkönen, Johanna, Mönkkönen, Hannu, Auriola, Seppo, Mönkkönen, Jukka

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Nitrogen-containing bisphosphonates can inhibit angiogenesis in vivo without the involvement of farnesyl pyrophosphate synthase von Stresing, Verena, Fournier, Pierrick G, Bellahcène, Akeila, Benzaïd, Ismahène, Mönkkönen, Hannu, Colombel, Marc, Ebetino, F. Hal, Castronovo, Vincent, Clézardin, Philippe

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Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography–electrospray ionization mass spectrometry von Jauhiainen, Marjo, Mönkkönen, Hannu, Räikkönen, Johanna, Mönkkönen, Jukka, Auriola, Seppo

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The cellular uptake and metabolism of clodronate in RAW 264 macrophages von MÖNKKÖNEN, Hannu, ROGERS, Michael J, MAKKONEN, Niina, NIVA, Sanna, AURIOLA, Seppo, MÖNKKÖNEN, Jukka

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In vitro Comparison of Clodronate, Pamidronate and Zoledronic Acid Effects on Rat Osteoclasts and Human Stem Cell‐Derived Osteoblasts von Kellinsalmi, Maarit, Mönkkönen, Hannu, Mönkkönen, Jukka, Leskelä, Hannu‐Ville, Parikka, Vilhelmiina, Hämäläinen, Martti, Lehenkari, Petri

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In Vivo Phosphoantigen Levels in Bisphosphonate-Treated Human Breast Tumors Trigger V gamma 9V delta 2 T-cell Antitumor Cytotoxicity through ICAM-1 Engagement von Benzaid, Ismahene, Monkkonen, Hannu, Bonnelye, Edith, Monkkonen, Jukka, Clezardin, Philippe

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Peripheral blood monocytes are responsible for γδ T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP von Roelofs, Anke J., Jauhiainen, Marjo, Mönkkönen, Hannu, Rogers, Michael J., Mönkkönen, Jukka, Thompson, Keith

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In Vivo Phosphoantigen Levels in Bisphosphonate-Treated Human Breast Tumors Trigger Vγ9Vδ2 T-cell Antitumor Cytotoxicity through ICAM-1 Engagement von BENZAÏD, Ismahène, MÖNKKÖNEN, Hannu, BONNELYE, Edith, MÖNKKÖNEN, Jukka, CLEZARDIN, Philippe

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High Phosphoantigen Levels in Bisphosphonate-Treated Human Breast Tumors Promote Vγ9Vδ2 T-Cell Chemotaxis and Cytotoxicity In Vivo von BENZAID, Ismahène, MÖNKKÖNEN, Hannu, STRESING, Verena, BONNELYE, Edith, GREEN, Jonathan, MÖNKKÖNEN, Jukka, TOURAINE, Jean-Louis, CLEZARDIN, Philippe

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Nitrogen-containing bisphosphonates and alkylamines activate Vγ9Vδ2 T cells through a common mechanism involving inhibition of the mevalonate pathway von Thompson, Keith, Mönkkönen ⁎, Hannu, Mönkkönen ⁎, Jukka, Rogers, MichaelJ

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Bisphosphonates in cancer therapy von Stresing, Verena, Daubiné, Florence, Benzaid, Ismahène, Mönkkönen, Hannu, Clézardin, Philippe

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