Mechanisms of RET signaling in cancer: Current and future implications for targeted therapy von Plaza-Menacho, I., Mologni, L., McDonald, N.Q.

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Treatment Efficacy and Resistance Mechanisms Using the Second-Generation ALK Inhibitor AP26113 in Human NPM-ALK-Positive Anaplastic Large Cell Lymphoma von Ceccon, M, Mologni, L, Giudici, G, Piazza, R, Pirola, A, Fontana, D, Gambacorti-Passerini, C

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α- Triazolylboronic acids: a novel scaffold to target FLT3 in AML von Introvigne, Maria Luisa, Destro, Lorenza, Mologni, Luca, Crippa, Valentina, Zardi, Paolo, Fini, Francesco, Prati, Fabio, Caselli, Emilia, Zambon, Alfonso

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Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency von Ceccon, M, Merlo, M E Boggio, Mologni, L, Poggio, T, Varesio, L M, Menotti, M, Bombelli, S, Rigolio, R, Manazza, A D, Di Giacomo, F, Ambrogio, C, Giudici, G, Casati, C, Mastini, C, Compagno, M, Turner, S D, Gambacorti-Passerini, C, Chiarle, R, Voena, C

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Targeting drug resistance mutations: Discovery of EUD-GK-91 chemical series von Zuccotto, F, Angiolini, M, Bernardi, A, Airaghi, F, Mologni, L, McDonald, N, Epemolu, O, Read, K

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Integrative multi-omics analysis enables a comprehensive characterization of prostate cancer and unveils metastasis-associated candidate biomarkers von Villa, M., Cazzaniga, G., Bolognesi, M., Crippa, V., Malighetti, F., Aroldi, A., Perri, D., Mazzoleni, F., Bozzini, G., Pagni, F., Piazza, R., Mologni, L., Ramazzotti, D.

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A0543 - Integrative multi-omics analysis enables a comprehensive characterization of prostate cancer and unveils metastasis-associated candidate biomarkers von Villa, M., Cazzaniga, G., Bolognesi, M., Crippa, V., Malighetti, F., Aroldi, A., Perri, D., Mazzoleni, F., Bozzini, G., Pagni, F., Piazza, R., Mologni, L., Ramazzotti, D.

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Retinoid-dependent growth inhibition, differentiation and apoptosis in acute promyelocytic leukemia cells. Expression and activation of caspases von Gianni, M, Ponzanelli, I, Mologni, L, Reichert, U, Rambaldi, A, Terao, M, Garattini, E

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P-027 Recurrent SETBP1 mutations in atypical chronic myeloid leukemia von Piazza, R, Valletta, S, Winkelmann, N, Redaelli, S, Spinelli, R, Pirola, A, Antolini, L, Mologni, L, Donadoni, C, Papaemmanuil, E, Schnittger, S, Kim, D.W, Boultwood, J, Rossi, F, Gaipa, G, De Martini, G.P, Di Celle, P.F, Jang, H.G, Fantin, V, Bignell, G.R, Magistroni, V, Haferlach, T, Pogliani, E.M, Campbell, P.J, Chase, A.J, Tapper, W.J, Cross, N.C, Gambacorti-Passerini, C

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194 - Targeting drug resistance mutations: Discovery of EUD-GK-91 chemical series von Zuccotto, F., Angiolini, M., Bernardi, A., Airaghi, F., Mologni, L., McDonald, N., Epemolu, O., Read, K.

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Induction of resistance to the Abelson inhibitor STI571 in human leukemic cells through gene amplification von le Coutre, Philipp, Tassi, Elena, Varella-Garcia, Marileila, Barni, Rossella, Mologni, Luca, Cabrita, Gonçalo, Marchesi, Edoardo, Supino, Rosanna, Gambacorti-Passerini, Carlo

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OP32 The gut virome-colonizing Orthohepadnavirus genus is associated with ulcerative colitis pathogenesis and induces intestinal inflammation in vivo von Facoetti, A, Massimino, L, Palmieri, O, Fuggetta, D, Spanò, S, D'Alessio, S, Furfaro, F, D'Amico, F, Zilli, A, Fiorino, G, Noviello, D, Latiano, A, Bossa, F, Pirola, A, Mologni, L, Piazza, R, Abbati, D, Perri, F, Bonini, C, Peyrin-Biroulet, L, Malesci, A, Danese, S, Ungaro, F

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Efficacy of a Cancer Vaccine against ALK-Rearranged Lung Tumors von Voena, Claudia, Menotti, Matteo, Mastini, Cristina, Di Giacomo, Filomena, Longo, Dario Livio, Castella, Barbara, Merlo, Maria Elena Boggio, Ambrogio, Chiara, Wang, Qi, Minero, Valerio Giacomo, Poggio, Teresa, Martinengo, Cinzia, D'Amico, Lucia, Panizza, Elena, Mologni, Luca, Cavallo, Federica, Altruda, Fiorella, Butaney, Mohit, Capelletti, Marzia, Inghirami, Giorgio, Jänne, Pasi A, Chiarle, Roberto

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Synthesis and biological evaluation of benzo[4,5]imidazo[1,2-c]pyrimidine and benzo[4,5]imidazo[1,2-a]pyrazine derivatives as anaplastic lymphoma kinase inhibitors von Tardy, Sébastien, Orsato, Alexandre, Mologni, Luca, Bisson, William H., Donadoni, Carla, Gambacorti-Passerini, Carlo, Scapozza, Leonardo, Gueyrard, David, Goekjian, Peter G.

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In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor von LE COUTRE, P, MOLOGNI, L, CLERIS, L, MARCHESI, E, BUCHDUNGER, E, GIARDINI, R, FORMELLI, F, GAMBACORTI-PASSERINI, C

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Unique Substrate Specificity of Anaplastic Lymphoma Kinase (ALK):  Development of Phosphoacceptor Peptides for the Assay of ALK Activity von Donella-Deana, Arianna, Marin, Oriano, Cesaro, Luca, Gunby, Rosalind H, Ferrarese, Anna, Coluccia, Addolorata M. L, Tartari, Carmen J, Mologni, Luca, Scapozza, Leonardo, Gambacorti-Passerini, Carlo, Pinna, Lorenzo A

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Inhibition of the ABL Kinase Activity Blocks the Proliferation of BCR/ABL+Leukemic Cells and Induces Apoptosis von Gambacorti-Passerini, Carlo, le Coutre, Philipp, Mologni, Luca, Fanelli, Mirco, Bertazzoli, Carla, Marchesi, Edoardo, Di Nicola, Massimo, Biondi, Andrea, Corneo, Gian Marco, Belotti, Daniela, Pogliani, Enrico, Lydon, Nicholas B.

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Inhibition of promyelocytic leukemia (PML)/retinoic acid receptor-α and PML expression in acute promyelocytic leukemia cells by anti-PML peptide nucleic acid von MOLOGNI, Luca, MARCHESI, Edoardo, NIELSEN, Peter E, GAMBACORTI-PASSERINI, Carlo

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Characterization of compound 584, an Abl kinase inhibitor with lasting effects von Puttini, Miriam, Redaelli, Sara, Moretti, Loris, Brussolo, Stefania, Gunby, Rosalind H, Mologni, Luca, Marchesi, Edoardo, Cleris, Loredana, Donella-Deana, Arianna, Drueckes, Peter, Sala, Elisa, Lucchini, Vittorio, Kubbutat, Michael, Formelli, Franca, Zambon, Alfonso, Scapozza, Leonardo, Gambacorti-Passerini, Carlo

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Characterization of mouse myotilin and its promoter von Mologni, Luca, Moza, Monica, Lalowski, Maciej M., Carpén, Olli

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