Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork von Choe, Katherine N., Moldovan, George-Lucian

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Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly von Thakar, Tanay, Leung, Wendy, Nicolae, Claudia M., Clements, Kristen E., Shen, Binghui, Bielinsky, Anja-Katrin, Moldovan, George-Lucian

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CRISPR screens guide the way for PARP and ATR inhibitor biomarker discovery von Schleicher, Emily M., Moldovan, George‐Lucian

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How the fanconi anemia pathway guards the genome von Moldovan, George-Lucian, D'Andrea, Alan D

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The KU-PARP14 axis differentially regulates DNA resection at stalled replication forks by MRE11 and EXO1 von Dhoonmoon, Ashna, Nicolae, Claudia M., Moldovan, George-Lucian

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Activation of Wnt signaling promotes olaparib resistant ovarian cancer von Yamamoto, Tomomi M., McMellen, Alexandra, Watson, Zachary L., Aguilera, Jennifer, Ferguson, Rebecca, Nurmemmedov, Elmar, Thakar, Tanay, Moldovan, George‐Lucian, Kim, Hyunmin, Cittelly, Diana M., Joglar, Annette M., Brennecke, Elyse P., Wilson, Heidi, Behbakht, Kian, Sikora, Matthew J., Bitler, Benjamin G.

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PARP14 regulates cyclin D1 expression to promote cell-cycle progression von O’Connor, Michael J., Thakar, Tanay, Nicolae, Claudia M., Moldovan, George-Lucian

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WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells von Datta, Arindam, Biswas, Kajal, Sommers, Joshua A., Thompson, Haley, Awate, Sanket, Nicolae, Claudia M., Thakar, Tanay, Moldovan, George-Lucian, Shoemaker, Robert H., Sharan, Shyam K., Brosh, Robert M.

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Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens von Clements, Kristen E., Schleicher, Emily M., Thakar, Tanay, Hale, Anastasia, Dhoonmoon, Ashna, Tolman, Nathanial J., Sharma, Anchal, Liang, Xinwen, Imamura Kawasawa, Yuka, Nicolae, Claudia M., Wang, Hong-Gang, De, Subhajyoti, Moldovan, George-Lucian

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Multi-step processing of replication stress-derived nascent strand DNA gaps by MRE11 and EXO1 nucleases von Hale, Anastasia, Dhoonmoon, Ashna, Straka, Joshua, Nicolae, Claudia M., Moldovan, George-Lucian

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Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly through PCNA-dependent CAF-1 recycling von Thakar, Tanay, Dhoonmoon, Ashna, Straka, Joshua, Schleicher, Emily M., Nicolae, Claudia M., Moldovan, George-Lucian

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STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability von Ranoa, Diana Rose E, Widau, Ryan C, Mallon, Stephen, Parekh, Akash D, Nicolae, Claudia M, Huang, Xiaona, Bolt, Michael J, Arina, Ainhoa, Parry, Renate, Kron, Stephen J, Moldovan, George-Lucian, Khodarev, Nikolai N, Weichselbaum, Ralph R

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Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells von Clements, Kristen E, Thakar, Tanay, Nicolae, Claudia M, Liang, Xinwen, Wang, Hong-Gang, Moldovan, George-Lucian

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RAD6 -dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO von Jentsch, Stefan, Hoege, Carsten, Pfander, Boris, Moldovan, George-Lucian, Pyrowolakis, George

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SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase von Sacher, Meik, Pfander, Boris, Jentsch, Stefan, Moldovan, George-Lucian, Hoege, Carsten

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The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1 von Hirschler-Laszkiewicz, Iwona, Festa, Fernanda, Huang, Suming, Moldovan, George-Lucian, Nicolae, Claudia, Dhoonmoon, Ashna, Bao, Lei, Keefer, Kerry, Chen, Shu-jen, Wang, Hong-Gang, Cheung, Joseph Y., Miller, Barbara A.

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Inhibition of Homologous Recombination by the PCNA-Interacting Protein PARI von Moldovan, George-Lucian, Dejsuphong, Donniphat, Petalcorin, Mark I.R., Hofmann, Kay, Takeda, Shunichi, Boulton, Simon J., D'Andrea, Alan D.

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NFκB regulates p21 expression and controls DNA damage-induced leukemic differentiation von Nicolae, Claudia M., O’Connor, Michael J., Constantin, Daniel, Moldovan, George-Lucian

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Mechanisms of DNA Damage Tolerance: Post-Translational Regulation of PCNA von Leung, Wendy, Baxley, Ryan M, Moldovan, George-Lucian, Bielinsky, Anja-Katrin

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Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors von Schleicher, Emily M., Dhoonmoon, Ashna, Jackson, Lindsey M., Clements, Kristen E., Stump, Coryn L., Nicolae, Claudia M., Moldovan, George-Lucian

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