Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapies von Moilanen, Anu-Maarit, Riikonen, Reetta, Oksala, Riikka, Ravanti, Laura, Aho, Eija, Wohlfahrt, Gerd, Nykänen, Pirjo S., Törmäkangas, Olli P., Palvimo, Jorma J., Kallio, Pekka J.

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Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human α‐synuclein von Lakso, Merja, Vartiainen, Suvi, Moilanen, Anu‐Maarit, Sirviö, Jouni, Thomas, James H., Nass, Richard, Blakely, Randy D., Wong, Garry

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ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity von Holmström, Tim H, Moilanen, Anu-Maarit, Ikonen, Tarja, Björkman, Mari L, Linnanen, Tero, Wohlfahrt, Gerd, Karlsson, Stefan, Oksala, Riikka, Korjamo, Timo, Samajdar, Susanta, Rajagopalan, Srinivasan, Chelur, Shekar, Narayanan, Kishore, Ramachandra, Raghuveer K, Mani, Jiju, Nair, Rashmi, Gowda, Nagaraj, Anthony, Thomas, Dhodheri, Samiulla, Mukherjee, Subhendu, Ujjinamatada, Ravi K, Srinivas, Nanduri, Ramachandra, Murali, Kallio, Pekka J

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Identification of a Novel RING Finger Protein as a Coregulator in Steroid Receptor-Mediated Gene Transcription von Moilanen, Anu-Maarit, Poukka, Hetti, Karvonen, Ulla, Häkli, Marika, Jänne, Olli A., Palvimo, Jorma J.

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A Testis-specific Androgen Receptor Coregulator That Belongs to a Novel Family of Nuclear Proteins von Moilanen, Anu-Maarit, Karvonen, Ulla, Poukka, Hetti, Yan, Wei, Toppari, Jorma, Jänne, Olli A., Palvimo, Jorma J.

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Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors von Goswami, Rajeev, Mukherjee, Subhendu, Wohlfahrt, Gerd, Ghadiyaram, Chakshusmathi, Nagaraj, Jwala, Chandra, Beeram Ravi, Sistla, Ramesh K, Satyam, Leena K, Samiulla, Dodheri S, Moilanen, Anu, Subramanya, Hosahalli S, Ramachandra, Murali

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Faulty Epithelial Polarity Genes and Cancer von Tervonen, Topi A., Partanen, Johanna I., Saarikoski, Sirkku T., Myllynen, Mikko, Marques, Elsa, Paasonen, Katriina, Moilanen, Anu, Wohlfahrt, Gerd, Kovanen, Panu E., Klefstrom, Juha

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Activation of androgen receptor function by a novel nuclear protein kinase von Moilanen, A M, Karvonen, U, Poukka, H, Jänne, O A, Palvimo, J J

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Mutual Transcriptional Interference between RelA and Androgen Receptor von Palvimo, J J, Reinikainen, P, Ikonen, T, Kallio, P J, Moilanen, A, Jänne, O A

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Abstract 3827: Antitumor activity of ODM-207, a novel BET bromodomain inhibitor, in nonclinical models of ER+ breast cancer as single agent and as a combination treatment von Lindqvist, Julia, Björkman, Mari, Riikonen, Reetta, Nicorici, Daniel, Mattila, Elina, Jaleel, Mahaboobi, Abbineni, Chandrasekhar, Moilanen, Anu-Maarit

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Novel ATPase of SNF2-like protein family interacts with androgen receptor and modulates androgen-dependent transcription von Rouleau, Nathalie, Domans'kyi, Andrii, Reeben, Mati, Moilanen, Anu-Maarit, Havas, Kristina, Kang, Zhigang, Owen-Hughes, Tom, Palvimo, Jorma J, Jänne, Olli A

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Abstract 674: ODM-201 - New generation androgen receptor inhibitor targeting resistance mechanisms to androgen signalling-directed prostate cancer therapies von Moilanen, Anu-Maarit, Riikonen, Reetta, Kallio, Pekka J.

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Abstract 3970: Therapeutic targeting of estrogen receptor positive breast cancer with the BET bromodomain inhibitor ODM-207 von Lindqvist, Julia, Björkman, Mari, Riikonen, Reetta, Nicorici, Daniel, Mattila, Elina, Abbineni, Chandrasekhar, Jaleel, Mahaboobi, Eriksson, John, Kallio, Pekka, Moilanen, Anu-Maarit

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Discovery and development of ODM-204: A Novel nonsteroidal compound for the treatment of castration-resistant prostate cancer by blocking the androgen receptor and inhibiting CYP17... von Oksala, Riikka, Moilanen, Anu, Riikonen, Reetta, Rummakko, Petteri, Karjalainen, Arja, Passiniemi, Mikko, Wohlfahrt, Gerd, Taavitsainen, Päivi, Malmström, Chira, Ramela, Meri, Metsänkylä, Hanna-Maija, Huhtaniemi, Riikka, Kallio, Pekka J., Mustonen, Mika VJ

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Abstract LB-113: Immune-mediated anti-tumor activity with a clinical stage BET bromodomain inhibitor ODM-207 in pre-clinical models von Deshpande, Pratima, Babu, Ravi Krishna, Vadnal, Prashant Yallappa, Jaleel, Mahaboobi, Ramachandra, Murali, Abbineni, Chandrasekhar, Samajdar, Susanta, Moilanen, Anu-Maarit, Kallio, Pekka

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Abstract 1754: First in class orally bioavailable BETBRD degraders von Abbineni, Chandrasekhar, Jaleel, Mahaboobi, Mukherjee, Subhendu, Marappan, Sivapriya, Tiwari, Nirbhay Kumar, Samiulla, DS, Aravind, AB, Kumar, Naveen R, Bansal, Indu, Reddy, Raghurami B, Bandaru, NVM Rao, Srinivas, Akhila, Maben, Janith Mary, Tgore, Suraj, Kumar, Avainash, Nankar, Rakesh P., Naik, Chandranath D., Antony, Thomas, Nellore, Kavitha, Giri, Sanjeev, Daginakatte, Girish, Chelur, Shekar, Törmäkangas, Olli, Wohlfahrt, Gerd, Björkman, Mari, Mattila, Elina, Ravanti, Laura, Moilanen, Anu, Ramachandra, Murali, Samajdar, Susanta

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Abstract 1753: Targeting cancer with selective cbp/p300 bromodomain inhibitors von Jaleel, Mahaboobi, Senaiar, Ramesh S., Abbineni, Chandrasekhar, Renukappa, Girish A., Mukherjee, Subhendu, Marappan, Sivapriya, Samiulla, DS, Aravind, AB, Kumar, Naveen R., Reddy, Venkata Siva N., Babu, Asha, Srinivas, Akhila P., Yadlapalli, Prasad, Tgore, Suraj, NR, Raghavendra, Naik, Chandranath D., Giri, Sanjeev, Antony, Thomas, Nellore, Kavitha, Chelur, Shekar, Daginakatte, Girish, Ravanti, laura, Myllymäki, Mikko, Wohlfahrt, Gerd, Mattila, Elina, Karlsson, Stefan, Björkman, Mari, Riikonen, Reetta, Ikonen, Tarja, Leimu, Laura, Mälmström, Chira, Korjamo, Timo, Moilanen, Anu, Ramachandra, Murali, Samajdar, Susanta

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ODM-204: A novel dual inhibitor of CYP17A1 and androgen receptor for the treatment of castration-resistant prostate cancer—Preclinical data von Oksala, Riikka, Moilanen, Anu, Riikonen, Reetta, Rummakko, Petteri, Huhtaniemi, Riikka, Kallio, Pekka

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Abstract 6179: Comparative study of Polθ helicase and polymerase inhibitor biochemical and cellular potency von Ahlskog, Johanna K., Pohjakallio, Antti, Paul, Ralf, Augustin, Martin, Schneider, Elisabeth, Johri, Sakshi, Tervahauta, Tuomas, Beisel, Hans-Georg, Neumann, Lars, Lindqvist, Julia, Moilanen, Anu

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ODM-204, a novel dual inhibitor of CYP17A1 and androgen receptor for the treatment of castration-resistant prostate cancer von Kallio, Pekka, Oksala, Riikka, Moilanen, Anu, Riikonen, Reetta, Rummakko, Petteri, Malmström, Chira, Mustonen, Mika VJ

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