Decompensated MASH-Cirrhosis Model by Acute and Toxic Effects of Phenobarbital von Kraus, Nico, Uschner, Frank Erhard, Moeslein, Magnus, Schierwagen, Robert, Gu, Wenyi, Brol, Maximilian Joseph, Fürst, Eike, Grünewald, Inga, Lotersztajn, Sophie, Rautou, Pierre-Emmanuel, Duran-Güell, Marta, Flores Costa, Roger, Clària, Joan, Trebicka, Jonel, Klein, Sabine

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Development and characterization of novel rodent ACLF models von Uschner, Frank Erhard, Costa, Roger Flores, Kraus, Nico, Moeslein, Magnus, Schierwagen, Robert, Gu, Wenyi, Brol, Maximilian Joseph, Lotersztajn, Sophie, Rautou, Pierre-Emmanuel, Clària, Joan, Trebicka, Jonel

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THU-356 - Development and characterization of novel rodent ACLF models von Uschner, Frank Erhard, Costa, Roger Flores, Kraus, Nico, Moeslein, Magnus, Schierwagen, Robert, Gu, Wenyi, Brol, Maximilian Joseph, Lotersztajn, Sophie, Rautou, Pierre-Emmanuel, Clària, Joan, Trebicka, Jonel

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Risks of Less Common Cancers in Proven Mutation Carriers With Lynch Syndrome von ENGEL, Christoph, LOEFFLER, Markus, SCHMIEGEL, Wolff, BUETTNER, Reinhard, MOESLEIN, Gabriela, LETTEBOER, Tom G. W, GOMEZ GARCIA, Encarna, HES, Frederik J, HOOGERBRUGGE, Nicoline, MENKO, Fred H, VAN OS, Theo A. M, SIJMONS, Rolf H, STEINKE, Verena, WAGNER, Anja, KLUIJT, Irma, PROPPING, Peter, VASEN, Hans F. A, RAHNER, Nils, HOLINSKI-FEDER, Elke, DIETMAIER, Wolfgang, SCHACKERT, Hans K, GOERGENS, Heike, VON KNEBEL DOEBERITZ, Magnus, GOECKE, Timm O

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The “unnatural” history of colorectal cancer in Lynch syndrome: Lessons from colonoscopy surveillance von Ahadova, Aysel, Seppälä, Toni T., Engel, Christoph, Gallon, Richard, Burn, John, Holinski‐Feder, Elke, Steinke‐Lange, Verena, Möslein, Gabriela, Nielsen, Maartje, Broeke, Sanne W., Laghi, Luigi, Dominguez‐Valentin, Mev, Capella, Gabriel, Macrae, Finlay, Scott, Rodney, Hüneburg, Robert, Nattermann, Jacob, Hoffmeister, Michael, Brenner, Hermann, Bläker, Hendrik, Knebel Doeberitz, Magnus, Sampson, Julian R., Vasen, Hans, Mecklin, Jukka‐Pekka, Møller, Pål, Kloor, Matthias

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No Difference in Colorectal Cancer Incidence or Stage at Detection by Colonoscopy Among 3 Countries With Different Lynch Syndrome Surveillance Policies von Engel, Christoph, Vasen, Hans F., Seppälä, Toni, Aretz, Stefan, Bigirwamungu-Bargeman, Marloes, de Boer, Sybrand Y., Bucksch, Karolin, Büttner, Reinhard, Holinski-Feder, Elke, Holzapfel, Stefanie, Hüneburg, Robert, Jacobs, Maarten A.J.M., Järvinen, Heikki, Kloor, Matthias, von Knebel Doeberitz, Magnus, Koornstra, Jan J., van Kouwen, Mariette, Langers, Alexandra M., van de Meeberg, Paul C., Morak, Monika, Möslein, Gabriela, Nagengast, Fokko M., Pylvänäinen, Kirsi, Rahner, Nils, Renkonen-Sinisalo, Laura, Sanduleanu, Silvia, Schackert, Hans K., Schmiegel, Wolff, Schulmann, Karsten, Steinke-Lange, Verena, Strassburg, Christian P., Vecht, Juda, Verhulst, Marie-Louise, de Vos tot Nederveen Cappel, Wouter, Zachariae, Silke, Mecklin, Jukka-Pekka, Loeffler, Markus

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The Different Immune Profiles of Normal Colonic Mucosa in Cancer-Free Lynch Syndrome Carriers and Lynch Syndrome Colorectal Cancer Patients von Bohaumilitzky, Lena, Kluck, Klaus, Hüneburg, Robert, Gallon, Richard, Nattermann, Jacob, Kirchner, Martina, Kristiansen, Glen, Hommerding, Oliver, Pfuderer, Pauline L., Wagner, Lelia, Echterdiek, Fabian, Kösegi, Svenja, Müller, Nico, Fischer, Konstantin, Nelius, Nina, Hartog, Ben, Borthwick, Gillian, Busch, Elena, Haag, Georg Martin, Bläker, Hendrik, Möslein, Gabriela, von Knebel Doeberitz, Magnus, Seppälä, Toni T., Ahtiainen, Maarit, Mecklin, Jukka-Pekka, Bishop, D. Timothy, Burn, John, Stenzinger, Albrecht, Budczies, Jan, Kloor, Matthias, Ahadova, Aysel

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Lower Incidence of Colorectal Cancer and Later Age of Disease Onset in 27 Families With Pathogenic MSH6 Germline Mutations Compared With Families With MLH1 or MSH2 Mutations: The G... von PLASCHKE, Jens, ENGEL, Christoph, RÜSCHOFF, Jose, LOEFFLER, Markus, SCHACKERT, Hans K, KRÜGER, Stefan, HOLINSKI-FEDER, Elke, PAGENSTECHER, Constanze, MANGOLD, Elisabeth, MOESLEIN, Gabriela, SCHULMANN, Karsten, GEBERT, Johannes, VON KNEBEL DOEBERITZ, Magnus

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Is HLA type a possible cancer risk modifier in Lynch syndrome? von Ahadova, Aysel, Witt, Johannes, Haupt, Saskia, Gallon, Richard, Hüneburg, Robert, Nattermann, Jacob, Broeke, Sanne, Bohaumilitzky, Lena, Hernandez‐Sanchez, Alejandro, Santibanez‐Koref, Mauro, Jackson, Michael S., Ahtiainen, Maarit, Pylvänäinen, Kirsi, Andini, Katarina, Grolmusz, Vince Kornel, Möslein, Gabriela, Dominguez‐Valentin, Mev, Møller, Pål, Fürst, Daniel, Sijmons, Rolf, Borthwick, Gillian M., Burn, John, Mecklin, Jukka‐Pekka, Heuveline, Vincent, Knebel Doeberitz, Magnus, Seppälä, Toni, Kloor, Matthias

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Adenoma and colorectal cancer risks in Lynch syndrome, Lynch‐like syndrome and familial colorectal cancer type X von Bucksch, Karolin, Zachariae, Silke, Ahadova, Aysel, Aretz, Stefan, Büttner, Reinhard, Görgens, Heike, Holinski‐Feder, Elke, Hüneburg, Robert, Kloor, Matthias, Knebel Doeberitz, Magnus, Ladigan‐Badura, Swetlana, Moeslein, Gabriela, Morak, Monika, Nattermann, Jacob, Nguyen, Huu Phuc, Perne, Claudia, Redler, Silke, Schmetz, Ariane, Steinke‐Lange, Verena, Surowy, Harald, Vangala, Deepak B., Weitz, Jürgen, Loeffler, Markus, Engel, Christoph

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Cancer risks in Lynch syndrome, Lynch-like syndrome, and familial colorectal cancer type X: a prospective cohort study von Bucksch, Karolin, Zachariae, Silke, Aretz, Stefan, Büttner, Reinhard, Holinski-Feder, Elke, Holzapfel, Stefanie, Hüneburg, Robert, Kloor, Matthias, von Knebel Doeberitz, Magnus, Morak, Monika, Möslein, Gabriela, Nattermann, Jacob, Perne, Claudia, Rahner, Nils, Schmiegel, Wolff, Schulmann, Karsten, Steinke-Lange, Verena, Strassburg, Christian P, Vangala, Deepak B, Weitz, Jürgen, Loeffler, Markus, Engel, Christoph

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Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome von Engel, Christoph, Ahadova, Aysel, Seppälä, Toni T., Aretz, Stefan, Bigirwamungu-Bargeman, Marloes, Bläker, Hendrik, Bucksch, Karolin, Büttner, Reinhard, de Vos tot Nederveen Cappel, Wouter T., Endris, Volker, Holinski-Feder, Elke, Holzapfel, Stefanie, Hüneburg, Robert, Jacobs, Maarten A.J.M., Koornstra, Jan J., Langers, Alexandra M., Lepistö, Anna, Morak, Monika, Möslein, Gabriela, Peltomäki, Päivi, Pylvänäinen, Kirsi, Rahner, Nils, Renkonen-Sinisalo, Laura, Schulmann, Karsten, Steinke-Lange, Verena, Stenzinger, Albrecht, Strassburg, Christian P., van de Meeberg, Paul C., van Kouwen, Mariette, van Leerdam, Monique, Vangala, Deepak B., Vecht, Juda, Verhulst, Marie-Louise, von Knebel Doeberitz, Magnus, Weitz, Jürgen, Zachariae, Silke, Loeffler, Markus, Mecklin, Jukka-Pekka, Kloor, Matthias, Vasen, Hans F.

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HNPCC-associated small bowel cancer: Clinical and molecular characteristics von Schulmann, Karsten, Brasch, Frank E., Kunstmann, Erdmute, Engel, Christoph, Pagenstecher, Constanze, Vogelsang, Holger, Krüger, Stefan, Vogel, Tilman, Knaebel, Hanns-Peter, Rüschoff, Josef, Hahn, Stephan A., Knebel-Doeberitz, Magnus V., Moeslein, Gabriela, Meltzer, Stephen J., Schackert, Hans K., Tympner, Christiane, Mangold, Elisabeth, Schmiegel, Wolff

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Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report von Dominguez-Valentin, Mev, Seppälä, Toni T, Sampson, Julian R, Macrae, Finlay, Winship, Ingrid, Evans, D Gareth, Scott, Rodney J, Burn, John, Möslein, Gabriela, Bernstein, Inge, Pylvänäinen, Kirsi, Renkonen-Sinisalo, Laura, Lepistö, Anna, Lindblom, Annika, Plazzer, John-Paul, Tjandra, Douglas, Thomas, Huw, Green, Kate, Lalloo, Fiona, Crosbie, Emma J, Hill, James, Capella, Gabriel, Pineda, Marta, Navarro, Matilde, Vidal, Joan Brunet, Rønlund, Karina, Nielsen, Randi Thyregaard, Yilmaz, Mette, Elvang, Louise Laurberg, Katz, Lior, Nielsen, Maartje, Ten Broeke, Sanne W, Nakken, Sigve, Hovig, Eivind, Sunde, Lone, Kloor, Matthias, Knebel Doeberitz, Magnus V, Ahadova, Aysel, Lindor, Noralane, Steinke-Lange, Verena, Holinski-Feder, Elke, Mecklin, Jukka-Pekka, Møller, Pål

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Age‐dependent performance of BRAF mutation testing in Lynch syndrome diagnostics von Bläker, Hendrik, Haupt, Saskia, Morak, Monika, Holinski‐Feder, Elke, Arnold, Alexander, Horst, David, Sieber‐Frank, Julia, Seidler, Florian, Winterfeld, Moritz, Alwers, Elizabeth, Chang‐Claude, Jenny, Brenner, Hermann, Roth, Wilfried, Engel, Christoph, Löffler, Markus, Möslein, Gabriela, Schackert, Hans‐Konrad, Weitz, Jürgen, Perne, Claudia, Aretz, Stefan, Hüneburg, Robert, Schmiegel, Wolff, Vangala, Deepak, Rahner, Nils, Steinke‐Lange, Verena, Heuveline, Vincent, von Knebel Doeberitz, Magnus, Ahadova, Aysel, Hoffmeister, Michael, Kloor, Matthias

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Efficacy of Annual Colonoscopic Surveillance in Individuals With Hereditary Nonpolyposis Colorectal Cancer von Engel, Christoph, Rahner, Nils, Schulmann, Karsten, Holinski–Feder, Elke, Goecke, Timm O, Schackert, Hans K, Kloor, Matthias, Steinke, Verena, Vogelsang, Holger, Möslein, Gabriela, Görgens, Heike, Dechant, Stefan, von Knebel Doeberitz, Magnus, Rüschoff, Josef, Friedrichs, Nicolaus, Büttner, Reinhard, Loeffler, Markus, Propping, Peter, Schmiegel, Wolff

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On Assessing Trustworthy AI in Healthcare. Machine Learning as a Supportive Tool to Recognize Cardiac Arrest in Emergency Calls von Zicari, Roberto V., Brusseau, James, Blomberg, Stig Nikolaj, Christensen, Helle Collatz, Coffee, Megan, Ganapini, Marianna B., Gerke, Sara, Gilbert, Thomas Krendl, Hickman, Eleanore, Hildt, Elisabeth, Holm, Sune, Kühne, Ulrich, Madai, Vince I., Osika, Walter, Spezzatti, Andy, Schnebel, Eberhard, Tithi, Jesmin Jahan, Vetter, Dennis, Westerlund, Magnus, Wurth, Renee, Amann, Julia, Antun, Vegard, Beretta, Valentina, Bruneault, Frédérick, Campano, Erik, Düdder, Boris, Gallucci, Alessio, Goffi, Emmanuel, Haase, Christoffer Bjerre, Hagendorff, Thilo, Kringen, Pedro, Möslein, Florian, Ottenheimer, Davi, Ozols, Matiss, Palazzani, Laura, Petrin, Martin, Tafur, Karin, Tørresen, Jim, Volland, Holger, Kararigas, Georgios

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Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study von Krüger, Stefan, Silber, Ann-Sophie, Engel, Christoph, Görgens, Heike, Mangold, Elisabeth, Pagenstecher, Constanze, Holinski-Feder, Elke, von Knebel Doeberitz, Magnus, Moeslein, Gabriela, Dietmaier, Wolfgang, Stemmler, Susanne, Friedl, Waltraut, Rüschoff, Josef, Schackert, Hans K

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Absence of association between cyclin D1 ( CCND1) G870A polymorphism and age of onset in hereditary nonpolyposis colorectal cancer von Krüger, Stefan, Engel, Christoph, Bier, Andrea, Mangold, Elisabeth, Pagenstecher, Constanze, von Knebel Doeberitz, Magnus, Holinski-Feder, Elke, Moeslein, Gabriela, Keller, Gisela, Kunstmann, Erdmute, Friedl, Waltraut, Plaschke, Jens, Rüschoff, Josef, Schackert, Hans K., The German HNPCC-Consortium

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Microsatellite instability of selective target genes in HNPCC-associated colon adenomas von Woerner, Stefan M, Kloor, Matthias, Mueller, Annegret, Rueschoff, Josef, Friedrichs, Nicolaus, Buettner, Reinhard, Buzello, Moriz, Kienle, Peter, Knaebel, Hanns-Peter, Kunstmann, Erdmute, Pagenstecher, Constanze, Schackert, Hans K, Möslein, Gabriela, Vogelsang, Holger, von Knebel Doeberitz, Magnus, Gebert, Johannes F

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