Alzheimer Disease Pathogenesis: Insights From Molecular and Cellular Biology Studies of Oligomeric Aβ and Tau Species von Chen, Xu-Qiao, Mobley, William C

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Exploring the Pathogenesis of Alzheimer Disease in Basal Forebrain Cholinergic Neurons: Converging Insights From Alternative Hypotheses von Chen, Xu-Qiao, Mobley, William C

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Implications for treatment: GABAA receptors in aging, Down syndrome and Alzheimer’s disease von Rissman, Robert A., Mobley, William C.

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Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration von Xu, Wei, Weissmiller, April M, White, 2nd, Joseph A, Fang, Fang, Wang, Xinyi, Wu, Yiwen, Pearn, Matthew L, Zhao, Xiaobei, Sawa, Mariko, Chen, Shengdi, Gunawardena, Shermali, Ding, Jianqing, Mobley, William C, Wu, Chengbiao

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BDNF/TrkB signaling endosomes in axons coordinate CREB/mTOR activation and protein synthesis in the cell body to induce dendritic growth in cortical neurons von Moya-Alvarado, Guillermo, Tiburcio-Felix, Reynaldo, Ibáñez, María Raquel, Aguirre-Soto, Alejandro A, Guerra, Miguel V, Wu, Chengbiao, Mobley, William C, Perlson, Eran, Bronfman, Francisca C

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TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease von Zhao, Xiaobei, Chen, Xu-Qiao, Han, Eugene, Hu, Yue, Paik, Paul, Ding, Zhiyong, Overman, Julia, Lau, Alice L., Shahmoradian, Sarah H., Chiu, Wah, Thompson, Leslie M., Wu, Chengbiao, Mobley, William C.

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Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis von Zhao, Yingjun, Tseng, I-Chu, Heyser, Charles J., Rockenstein, Edward, Mante, Michael, Adame, Anthony, Zheng, Qiuyang, Huang, Timothy, Wang, Xin, Arslan, Pharhad E., Chakrabarty, Paramita, Wu, Chengbiao, Bu, Guojun, Mobley, William C., Zhang, Yun-wu, St. George-Hyslop, Peter, Masliah, Eliezer, Fraser, Paul, Xu, Huaxi

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Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome von Wang, Xin, Zhao, Yingjun, Zhang, Xiaofei, Badie, Hedieh, Zhou, Ying, Mu, Yangling, Loo, Li Shen, Cai, Lei, Thompson, Robert C, Yang, Bo, Chen, Yaomin, Johnson, Peter F, Wu, Chengbiao, Bu, Guojun, Mobley, William C, Zhang, Dongxian, Gage, Fred H, Ranscht, Barbara, Zhang, Yun-wu, Lipton, Stuart A, Hong, Wanjin, Xu, Huaxi

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One at a time, live tracking of NGF axonal transport using quantum dots von Cui, Bianxiao, Wu, Chengbiao, Chen, Liang, Ramirez, Alfredo, Bearer, Elaine L, Li, Wei-Ping, Mobley, William C, Chu, Steven

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BDNF and TRiC-inspired reagent rescue cortical synaptic deficits in a mouse model of Huntington's disease von Gu, Yingli, Pope, Alexander, Smith, Charlene, Carmona, Christopher, Johnstone, Aaron, Shi, Linda, Chen, Xuqiao, Santos, Sarai, Bacon-Brenes, Claire Cecile, Shoff, Thomas, Kleczko, Korbin M., Frydman, Judith, Thompson, Leslie M., Mobley, William C., Wu, Chengbiao

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Widespread changes in dendritic and axonal morphology in Mecp2-mutant mouse models of rett syndrome: Evidence for disruption of neuronal networks von Belichenko, Pavel V., Wright, Elena E., Belichenko, Nadia P., Masliah, Eliezer, Li, Hong Hua, Mobley, William C., Francke, Uta

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Down Syndrome Cognitive Phenotypes Modeled in Mice Trisomic for All HSA 21 Homologues von Belichenko, Pavel V, Kleschevnikov, Alexander M, Becker, Ann, Wagner, Grant E, Lysenko, Larisa V, Yu, Y Eugene, Mobley, William C

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Genetic dissection of the Down syndrome critical region von Jiang, Xiaoling, Liu, Chunhong, Yu, Tao, Zhang, Li, Meng, Kai, Xing, Zhuo, Belichenko, Pavel V, Kleschevnikov, Alexander M, Pao, Annie, Peresie, Jennifer, Wie, Sarah, Mobley, William C, Yu, Y Eugene

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Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome von Kleschevnikov, Alexander M, Yu, Jessica, Kim, Jeesun, Lysenko, Larisa V, Zhen, Zheng, Eugene Yu, Y, Mobley, William C

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Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down Syndrome: Activation of β1 -adrenergic receptor by xamoterol as a potential cognitive enhancer von Faizi, Mehrdad, Bader, Patrick L, Tun, Christine, Encarnacion, Angelo, Kleschevnikov, Alexander, Belichenko, Pavel, Saw, Nay, Priestley, Matthew, Tsien, Richard W, Mobley, William C, Shamloo, Mehrdad

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The "Down Syndrome Critical Region" Is Sufficient in the Mouse Model to Confer Behavioral, Neurophysiological, and Synaptic Phenotypes Characteristic of Down Syndrome von Belichenko, Nadia P, Belichenko, Pavel V, Kleschevnikov, Alexander M, Salehi, Ahmad, Reeves, Roger H, Mobley, William C

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Detailed evaluation of the upper airway in the Dp(16)1Yey mouse model of Down syndrome von Takahashi, Tatsunori, Sakai, Noriaki, Iwasaki, Tomonori, Doyle, Timothy C., Mobley, William C., Nishino, Seiji

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Illicium Sesquiterpenes: Divergent Synthetic Strategy and Neurotrophic Activity Studies von Trzoss, Lynnie, Xu, Jing, Lacoske, Michelle H., Mobley, William C., Theodorakis, Emmanuel A.

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Synaptic and cognitive abnormalities in mouse models of down syndrome: Exploring genotype-phenotype relationships von Belichenko, Pavel V., Kleschevnikov, Alexander M., Salehi, Ahmad, Epstein, Charles J., Mobley, William C.

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The 50th anniversary of the discovery of trisomy 21: The past, present, and future of research and treatment of Down syndrome von Mégarbané, André, Ravel, Aimé, Mircher, Clotilde, Sturtz, Franck, Grattau, Yann, Rethoré, Marie-Odile, Delabar, Jean-Maurice, Mobley, William C

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