Genome-scale CRISPR-Cas9 knockout studies to characterize the mechanisms of myeloma cell treatment resistance von Hu, Y, Sheffer, M, Matthews, G.M, Hengeveld, P, Shalem, O, Zhang, F, Dhimolea, E, Sarkar, S, Bariteau, M, Aftab, B, Groen, R, Mitsiades, C.S

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Functional mapping of multiple myeloma kinome with library of small molecule inhibitors von Dhimolea, E, King, E, Rogulin, V, Awate, P.P, Sheffer, M, Hu, Y, Sarkar, S, Murnane, M, Bariteau, M.A, Aftab, B, Mitsiades, C.S

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The use of novel agents in the treatment of relapsed and refractory multiple myeloma von Laubach, J P, Mahindra, A, Mitsiades, C S, Schlossman, R L, Munshi, N C, Ghobrial, I M, Carreau, N, Hideshima, T, Anderson, K C, Richardson, P G

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PF567 CHROMATIN ACTIVATION AS A UNIFYING PRINCIPLE UNDERLYING PATHOGENIC MECHANISMS IN MULTIPLE MYELOMA von Ordoñez, R., Kulis, M., Russiñol, N., Chapaprieta, V., Beekman, R., Meydan, C., Duran‐Ferrer, M., Verdaguer‐Dot, N., Clot, G., Vilarrasa‐Blasi, R., Garate, L., Miranda, E., Carrasco, A., Ezponda, T., Martens, J.H.A., El‐Omri, H., Taha, R.Y., Calasanz, M.J., Paiva, B., Miguel, J. San, Flicek, P., Gut, I., Melnick, A., Mitsiades, C.S., Licht, J.D., Campo, E., Stunnenberg, H.G., Agirre, X., Martin‐Subero, J.I., Prósper, F.

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The research mission in myeloma von Richardson, P G, San-Miguel, J, Lonial, S, Reece, D, Jakubowiak, A, Hussein, M, Jagannath, S, Mitsiades, C S, Raje, N, Kaufman, J, Avigan, D, Ghobrial, I, Schlossman, R L, Munshi, N, Dalton, W, Anderson, K C

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Lenalidomide Plus Bortezomib (Rev-Vel) in Relapsed and/or Refractory Multiple Myeloma (MM): Final Results of a Multicenter Phase 1 Trial von Richardson, Paul G., Jagannath, S., Avigan, D.E., Alsina, M., Schlossman, R.L., Mazumder, A., Munshi, N.C., Ghobrial, I., Doss, D., McKenney, M.L., Farrell, M.G., Warren, D.L., Lunde, L.E., Gourley, B., Vaccaro, S., Delaney, C., Pountney, S., Mitsiades, C.S., Hideshima, T., Byrne, C., Knight, R., Birner, A., Myers, T., Weller, E., Anderson, K.C.

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O-20 Noninvasive detection ofmyelodysplastic syndromes using serum proteome profiling von Aivado, M., Spentzos, D., Germing, U., Grall, F., Giagounidis, A.A.N., Otu, H.H., Gattermann, N., Haas, R., Mitsiades, C.S., Fungi, E.T., Libermann, T.A.

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An inhibitor of proteasome beta 2 sites sensitizes myeloma cells to immunoproteasome inhibitors von Downey-Kopyscinski, S., Daily, E.W., Gautier, M., Bhatt, A., Florea, B.I., Mitsiades, C.S., Richardson, P.G., Driessen, C., Overkleeft, H.S., Kisselev, A.F.

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